• Journal of the Institute of Convergence Signal Processing
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• v.9 no.1
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• pp.62-74
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• 2008

In this paper, we would like to propose the design of symmetric digital filter core in order to use in the radio astronomy. The function of FIR filter core would be designed by VHDL code required at the Data Acquisition System (DAS) of Korean VLBI Network (KVN) based on the FPGA chip of Vertex-4 SX55 model of Xilinx company. The designed digital filter has the symmetric structure to increase the effectiveness of system by sharing the digital filter coefficient. The SFFU(Symmetric FIR Filter Unit) use the parallel processing method to perform the data processing efficiently by using the constrained system clock. In this paper, therefore, for the effective design of SFFU, the Unified Synthesis software ISE Foundation and Core Generator which has excellent GUI environment were used to overall IP core synthesis and experiments. Through the synthesis results of digital filter core, we verified the resource usage is less than 40% such as Slice LUT and achieved the maximum operation frequency is more than 260MHz. We also confirmed the SFFU would be well operated without error according to the SFFU simulation result using the Modelsim 6.1a of Mentor Graphics Company. To verify the function of SFFU, we carried out the additional simulation experiments using the pseudo signal to the Matlab software. From the comparison experimental results of simulation and the designed digital FIR filter, we confirmed the FIR filter was well performed with filter's basic function. So we verified the effectiveness of the designed FIR digital filter with symmetric structure using FPGA and VHDL.

• The Journal of the Acoustical Society of Korea
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• v.28 no.3
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• pp.229-238
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• 2009

This paper describes a sound engine of Korean traditional instruments, which are the Gayageum and Taepyeongso, by using a TMS320F2812. The Gayageum and Taepyeongso models based on commuted waveguide synthesis (CWS) are required to synthesize each sound. There is an instrument selection button to choose one of instruments in the proposed sound engine, and thus a corresponding sound is produced by the relative model at every certain time. Every synthesized sound sample is transmitted to a DAC (TLV5638) using SPI communication, and it is played through a speaker via an audio interface. The length of the delay line determines a fundamental frequency of a desired sound. In order to determine the length of the delay line, it is needed that the time for synthesizing a sound sample should be checked by using a GPIO. It takes $28.6{\mu}s$ for the Gayageum and $21{\mu}s$ for the Taepyeongso, respectively. It happens that each sound sample is synthesized and transferred to the DAC in an interrupt service routine (ISR) of the proposed sound engine. A timer of the TMS320F2812 has four events for generating interrupts. In this paper, the interrupt is happened by using the period matching event of it, and the ISR is called whenever the interrupt happens, $60{\mu}s$. Compared to original sounds with their spectra, the results are good enough to represent timbres of instruments except 'Mu, Hwang, Tae, Joong' of the Taepyeongso. Moreover, only one sound is produced when playing the Taepyeongso and it takes $21{\mu}s$ for the real-time playing. In the case of the Gayageum, players usually use their two fingers (thumb and middle finger or thumb and index finger), so it takes $57.2{\mu}s$ for the real-time playing.

• The Proceedings of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.7 no.3
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• pp.27-33
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• 1993

This paper presents the &tal controller for driving high frequency voltage fed PWM inverter that carrier frequency is over 2OkHz.We analyzed the conventional PWM to select a proper PWM pattern. as the result, obtained PWM pattern of the controller in which asynchronus staircase sinusoidal waveform is used as reference signal, and variable carrier ratio method was used for PWM control. The PWM controller is designed by fully digital method. Especially, Thk proposed controller is consisted of 8 bit one-chip microprocessor and digital logic. the former is for arithmetic and data processing, and the latter is for PWM pattern synthesis. Therefore, The responsibility and controllability is improved. Also, Data processing capability is improved using proper program to output modulation index with 9 bits. Circuits configuration of digital controller are made up of one chip 8051 and EPLD, and its controllability is tested by operating voltage fed inverter. Harmonics and current waveform is evaluated and analyzed for the voltage fed inverter system.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.39 no.12
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• pp.513-519
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• 2002

This paper proposes a high-speed FFT processor for orthogonal frequency-division multiplexing(OFDM) systems. The Proposed architecture uses a single-memory architecture and uses a radix-4 algorithm for high speed. The proposed memory is partitioned into four banks for high-speed computation. It uses an in-place memory strategy that stores butterfly outputs in the same memory location used by butterfly inputs. Therefore, the memory size can be reduced. The SQNR of about 80dB is achieved with 20-bit input and 20-bit twiddle factors. The architecture has been modeled by VHDL and logic synthesis has been performed using the SamsungTM 0.5㎛ SOG cell library (KG80). The implemented FFT processor consists of 98,326 gates excluding memory. It has smaller hardware than existing pipeline FFT processors for more than 1024-point FFTs. The processor can operate at 42MHz and calculate a 256-point complex FFT in 6us. It satisfies tile required processing speed of 8.4㎲ in the HomePlug standard.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.16 no.7 s.98
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• pp.720-731
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• 2005

In this paper, radiation patterns of electrically small inverted-F antennas(IFAs) on an electrically large cylindrical conducting body like a satellite launcher are experimentally studied. First, radiation patterns are obtained by using method of moment and a commercial software tool, HFSS(High Frequency Structure Simulator) and the results are compared and analyzed with experimental ones. Especially, when the size of a cylindrical conducting body is electrically large, the effects of the size of a cylindrical conducting body on radiation patterns are studied by considering only the partial ground in vicinity of antennas. And then, when one and two inverted-F antennas are on the cylindrical conducting body, radiation patterns are simulated and investigated by using method of moment and HFSS. Good agreements are observed among the results by method of moment, HFSS, and experiments.

• The Korean Journal of Physiology and Pharmacology
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• v.1 no.6
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• pp.809-816
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• 1997

The present study was designed to investigate whether endogenous nitric oxide(EDNO) is involved in submandibular vasodilation and salivation induced by parasympathetic nerve stimulation. Effects of $N^w$-nitro-L-arginine-methyl ester (L-NAME) which blocks the synthesis of EDNO from L-arginine on the submandibular vasodilation and salivation induced by chords stimulation or administration of various vasodilators were examined in anesthetized cats. Effect of L-NAME on $K^+$ efflux induced by carbachol was also examined using the excised submandibular slice in vitro. In the submandibular slices, acetylcholine$(10^{-5}\;mol/L)$ or vasoactive intestinal polypeptide$(VIP,\;10^{-5}\;mol/L)$ increased $NO_2$ contents, which was Prevented by pretreatment with L-NAME. Salivary secretion in response to the chords stimulation$(3\;V,\;1\;msec,\;10{\sim}20\;Hz)$ was completely blocked by treatment with atropine(1 mg/kg). Increased blood flow response to the low frequency(1, 2, 5 Hz) stimulation was significantly reduced, whereas the blood flow induced by the higher frequency(10,20 Hz) stimulation was not affected. Lingual-arterial infusion of L-NAME(100 mg/kg) significantly diminished the vasodilatory and salivary responses to the chorda stimulation at all stimuli frequencies used. Intra-arterial infusion of L-NAME(100 mg/kg markedly diminished the vasodilatory responses to acetylcholine$(5\;{\mu}g/kg)$, VIP$(5\;{\mu}g/kg)$ or bradykinin$(5\;{\mu}g/kg)$. In the excised submandibular slice, $K^+$ efflux in response to carbachol$(10^{-5}\;mol/L)$ was significantly decrease by pretreatment with L-NAME$(10^{-5}\;mol/L)$. In the isolated submandibular artery precontracted with phenylephrine$(10^{-5}\;mol/L)$, the vasorelaxation induced by ACh$(10^{-7}\;mol/L)$ was reversed into a contraction by methylene blue$(10^{-4}\;mol/L)$. These results suggest that EDNO may play an important role in vasodilation and secretion of the submandibular gland.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.41 no.5
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• pp.153-160
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• 2004

In this paper, we propose an efficient bit loading algorithm for IEEE 802.11a wireless LAN systems. While a conventional bit loading algorithm uses the SNR value of each subcarrier, it is very difficult to estimate the exact SNR value in wireless LAN systems due to randomness of AWGN. Therefore, in order to solve this problem our proposed algorithm uses the channel frequency response instead of the SNR of each subcarrier. Through simulation results, we can obtain the performance gain of 3.5∼8㏈ at PER of 10-2 with the proposed bit loading algorithm while the conventional one obtains the performance gain of 0.5∼5㏈ at the same conditions. Also, the increased data rate can be confirmed 63Mbps. After the logic synthesis using 0.3${\mu}{\textrm}{m}$ CMOS technology, the logic gate count for the processor with proposed algorithm can be reduced by 34% in comparison with the conventional one.

• THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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• v.3 no.1
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• pp.67-84
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• 1997

Bujeonghangamtang(扶正抗癌湯) has been used for cure of tumor as a traditional medicine without any experimental evidence to support the rational basis for its clinical use. This study was carried out to evaluate the possible therapeutic or antitumoral effects of Bujeonghangamtang extract against tumor, and to carry out some mechanisms responsible for its effect. Some kinds of tumor were induced by the typical application of 3-methylcholanthrene. (MCA) or by the implantation(s.c) of malignant tumor cells such as leukemia cells(3LL cells) or sarcoma cells(Sl80 cells). Treatment of the Bujeonghangamtang water-extract (dailly 1mg／mouse, i. p.) was continued for 7 days prior to tumor induction and after that the treatment was lasted for 20 days. Against squamous cell carcinoma induced by MCA, Bujeonghangamtang decreased not only the frequency of tumor production but also the number and the weight of tumors per tumor bearing mice (TBM). Bujeonghangamtang also significantly suppressed the development of 3LL cell and S180 cell-implanted tumors in occurrence-frequency and their size, and some developed tumors were regressed by the continuous treatment of Bujeonghangamtang extract into TBM. In vitro, treatment of Bujeonghangamtang extract had no effect on the growth of some kinds of cell line such as FsaII, A431 strain but significantly inhibited the proliferation of 3LL, S180 cells and augmented the DNA synthesis of mitogen-activated lymphocytes. Bujeonghangamtang also stimulated the migrative ability of leukocyte, the MIF and IL-2 production of T lymphocytes, but not IL 6 production of B cells. Bujeonghangamtang-administration to mice enhanced NK cells activities. These results demonstrated that Bujeonghangamtang extract exhibited a significant prophylactic benefits against tumors and its antitumor activity was manifested depending on the type of tumor cells. And these results also suggested that effect of Bujeonghangamtang might be chiefly due to nonspecific enhancement of NK cell activities and cell-mediated immune responses.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.13 no.4
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• pp.145-149
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• 1980

Various methods have been so far proposed to find out the directions and spectra of sound waves from the sources for provisions of noise controls. The conventional methods are generally classified into three systems such as, single microphone system, moving microphone system and multi-microphone system, which composes a resultant super directivity by giving a appropriate delay and a weighting coefficient in the output of each microphone. In case of using a single microphone there is a difficulty in providing it with desirable super directivity in the low frequency range, while in case of using multi-microphone system there has been a disadvantage that the measurement of directivity could not separately be done with the spectrum analysing. And in case of the use of a moving microphone system it needs a condition that the sound source to be detected should be stationary state and in rest. However here we introduce a method that the spectral analysing and the directivity of synthesis can be separately carried out by using a linear array of many microphones, in which each output of the microphone is multiplied by appropriate weighting coefficient and all of those products are summed after passing through adequate filters. The resultant signal is then sampled with an adequate sampling frequency and taken average for processing.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10433-10438
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• 2015

Background: Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children and represents approximately 25% of cancer diagnoses among those younger than 15 years of age. Aim and Objectives: This study investigated substitutions in the ATP synthase subunit 6 gene of mitochondrial DNA (mtDNA) as a potential diagnostic biomarker for early detection and diagnosis of acute lymphoblastic leukemia. Based on mtDNA from 23 subjects diagnosed with acute lymphoblastic leukemia, approximately 465 bp of the ATP synthase subunit 6 gene were amplified and sequenced. Results: The sequencing revealed thirty-one mutations at 14 locations in ATP synthase subunit 6 of mtDNA in the ALL subjects. All were identified as single nucleotide polymorphisms (SNPs) with a homoplasmic pattern. The mutations were distributed between males and females. Novel haplotypes were identified in this investigation: haplotype (G) was recorded in 34% in diagnosed subjects; the second haplotype was (C) with frequency of 13% in ALL subjects. Neither of these were observed in control samples. Conclusions: These haplotypes were identified for the first time in acute lymphoblastic leukemia patients. Five mutations able to change amino acid synthesis for the ATP synthase subunit 6 were associated with acute lymphoblastic leukemia. This investigation could be used to provide an overview of incidence frequency of acute lyphoblastic leukemia (ALL) in Saudi patients based on molecular events.