• The Korean Journal of Physiology and Pharmacology
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• v.2 no.3
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• pp.297-305
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• 1998

This study used in vivo intracellular recording in rat hippocampus to evaluate the effect of lidocaine and MK-801 on the membrane properties and the synaptic responses of individual neurons to electrical stimulation of the commissural pathway. Cells in control group typically fired in a tonic discharge mode with an average firing frequency of $2.4{\pm}0.9$ Hz. Neuron in MK-801 treated group (0.2 mg/kg, i.p.) had an average input resistance of $3.28{\pm}5.7\;M{\Omega}$ and a membrane time constant of $7.4{\pm}1.8$ ms. These neurons exhibited $2.4{\pm}0.2$ ms spike durations, which were similar to the average spike duration recorded in the neurons of the control group. Slightly less than half of these neurons were firing spontaneously with an average discharge rate of $2.4{\pm}1.1$ Hz. The average peak amplitude of the AHP following the spikes in these groups was $7.4{\pm}0.6$ mV with respect to the resting membrane potential. Cells in MK-801 and lidocaine treated group (5 mg/kg, i.c.v.) had an average input resistance of $3.45{\pm}6.0\;M{\Omega}$ and an average time constant of $8.0{\pm}1.4$ ms. The cells were firing spontaneously at an average discharge rate of $0.6{\pm}0.4$ Hz. Upon depolarization of the membrane by 0.8 nA for 400 ms, all of the tested cells exhibited accommodation of spike discharge. The most common synaptic response contained an EPSP followed by early-IPSP and late-IPSP. Analysis of the voltage dependence revealed that the early-IPSP and late-IPSP were putative $Cl^--and\;K^+-dependent$, respectively. Systemic injection of the NMDA receptor blocker, MK-801, did not block synaptic responses to the stimulation of the commissural pathway. No significant modifications of EPSP, early-IPSP, or late-IPSP components were detected in the MK-801 and/or lidocaine treated group. These results suggest that MK-801 and lidocaine manifest their CNS effects through firing pattern of hippocampal pyramidal cells and neural network pattern by changing the synaptic efficacy and cellular membrane properties.

• 대한공업교육학회지
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• v.33 no.1
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• pp.191-212
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• 2008

The purpose of this study was to show how to organize small groups on the project method class in technical high school. The subjects of this study were two classes including 40 second-year students (20 students in each class) of architecture design course in D technical high school located in Taejeon metropolitan city. The method of this study was to investigate the ego-state by the ego-gram practicing Transactional Analysis. Total 10 small groups were organized. Each group had 4 members. And the same quality of egostate small group was organized by the 4 students who have high score on NP and AC. The different in kind small group was organized by the 4 students, each of whom has NP leading, A leading, FC leading and AC leading score. After the target small group was video- taped, students' verbal interaction was written into transcripts. Their individual states were analysed by the frame of verbal interaction. The result of this study was that the same quality of TAOK small group had more active interaction(110 times) than different in kind small group(87 times). The frequency of complementary transaction was also higher plenty in the same quality of TAOK small group.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.5
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• pp.67-73
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• 2016

Recently, wireless power transmission has attracted much interest and is the subject of much research in industry and academia. As its name implies, it is a technology which involves transferring power without wires. This paper presents the design of an ICT-based wireless power transmission system. The proposed system consists of a wireless transceiver unit and high-efficiency coil unit, which can increase both the transmission efficiency and the effective power distance. In particular, the wireless transceiver unit was designed to work with the ICT technique to enable real-time remote monitoring. Also, studies were done relating to the effect of reducing the standby power. The optimal frequency of IGBT devices used in industrial wireless power systems of 20[KHz] was utilized. The values of $23.9[{\mu}H]$ and $2.64[{\mu}F]$ were selected for L and C, respectively, through many field experiments designed to optimize the system design. In addition, an output current controlling algorithm was developed for the purpose of reducing the standby power. The results presented in this paper represent a 75[%] to 85[%] higher power transmission efficiency with a 10[%] increase in the effective power transmission distance compared with the existing systems. As a result, the proposed system exhibits a lower standby power and maintenance costs. Also, the designed wireless transceiver unit facilitates fault detection by means of user acquired data with the development of the ICT applied program.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.10
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• pp.6126-6133
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• 2014

This study examined the effects of a simulation-based core skill program regarding emergency care on the knowledge, problem solving process and self-esteem of health related department students. A quasi-experimental non-equivalent control group pre-post test design was used. A total of 46 students, 23 students for the experimental group and 23 students for the control group, were enrolled in this study. The simulation-based core skill program included lectures, skill training, team-based practice, simulation and debriefing. This was implemented in the experimental group for 3 weeks in May, 2013. The data was analyzed using the frequency, ratio, Chi-square, and t-test by the SPSS/Win 18.0. The experimental group, who had a simulation-based core skill program, showed significantly higher clinical knowledge, problem solving process and self-esteem compared to the control group who had a traditional education. A clinical simulation-based core skill program was verified to be an effective teaching method to improve on the clinical knowledge, problem solving process and self-esteem of health-related department students.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.2
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• pp.1109-1117
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• 2014

We study free vibration analysis of sigmoid functionally graded materials(S-FGM) nano-scale plates, using a nonlocal elasticity theory of Eringen in this paper. This theory has ability to capture the both small scale effects and sigmoid function in terms of the volume fraction of the constituents for material properties through the plate thickness. Numerical solutions of S-FGM nano-scale plate are presented using this theory to illustrate the effect of nonlocal theory on natural frequency of the S-FGM nano-scale plates. The relations between nonlocal and local theories are discussed by numerical results. Further, effects of (i) power law index (ii) nonlocal parameters, (iii) elastic modulus ratio and (iv) thickness and aspect ratios on nondimensional frequencies are investigated. In order to validate the present solutions, the reference solutions are compared and discussed. The results of S-FGM nano-scale plates using the nonlocal theory may be the benchmark test for the free vibration analysis.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.5
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• pp.601-611
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• 2016

The research, development and use of seismic isolation systems have been increasing with the gradual development of structure safety assurance methods for earthquakes. The High Damping Rubber Bearing (HDRB), one type of seismic isolation system, is a Laminated Rubber Bearing using special High Damping Rubber. However, as its damping function is slightly lower than that of the Lead Rubber Bearing, a similar seismic isolation system, its utilization has not been high. However, the HDRB has a superior damping force to the Natural Rubber Bearing, which has similar materials and shapes, and the existing Lead Rubber Bearing has a maleficence problem in that it contains lead. Thus, studies on HDRBs that do not use lead have increased. In this study, a test targeting the HDRB was done to examine its various dependence properties, such as its compressive stress, frequency and repeated loading. To evaluate the HDRB's seismic performance in response to several earthquake waves, the shaking table test was performed and the results analyzed. The test used the downscaled bridge model and the HDRB was divided into seismic and non-seismic isolation. Consequently, when the HDRB was applied, the damping effect was higher in the non-seismic case. However, its responses on weak foundations, such as in Mexico City, represented increased shapes. Thus, its seismic isolator.

• Korean Security Journal
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• no.29
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• pp.59-86
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• 2011

The purpose of this study is to investigate the relationship between organizational culture, organizational trust and organizational performance of special guard organization. This study had selected special guards from 4 different private guard companies which are in Seoul area on March 2011. Using Judgement Sampling, 161 samples were drawn for the use of final analysis. Questionnaire used in this study was consisted of the total 42 question, and executed frequency analysis, factor analysis, reliability analysis, correlation analysis, multiple regression analysis, path analysis by SPSSWIN 18.0. The Cronbach's ${\alpha}$ value which represents the reliability of the survey came out to be over .592. The results are following: First, the organizational culture of special guard organization affects organizational trust. That is, when a developmental, reasonable, consensual and hierarchical culture is activated, cognitive emotional and behavioral trust is increased. Second, organizational culture of special guard organization affects organizational performance. That is, when a reasonable and consensual culture is activated, job-satisfaction becomes higher. On the other hand, when a developmental, reasonable and hierarchical culture is activated, organizational flow becomes higher. Third, organizational trust of special guard organization affects organizational performance. That is, when a cognitive emotional and behavioral trust works highly, job-satisfaction and organizational flow is increased. Fourth, Special security organization's organizational culture affects as a result in organization result. As well as organizational culture exerts direct influence on organization outcome, I exert effect that is indirect in organization outcome through action trust which is low rank factor of organization trust.

• Informatization Policy
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• v.20 no.1
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• pp.42-60
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• 2013

In the information age, it is common to use the computer for company's business. Even though there are lots of investment to prevent the abuse of computer, the frequency and amount is increasing. Therefore, the purpose of this study is how individuals misusing computers in the company, and identifying factors of it separated by group and personal characteristics. Code of ethics and discipline has a significant impact on attitude and intention from the view of organizational characteristics. This proofs that code of ethics is clearly codified and reflect the management policy. So, it imprints employee's commitment to protect themselves, and this could be conjunction with the company's policy. Moreover, reflecting on performance assesment and discipline also has a effect. Organizational loyalty appeared significantly in attitude, but was not important in intentions. This means that the intensity of organizational loyalty is not always connected to the abuse of computer. It can be depending on individual's tendency, psychological state and organization mood. The action for misusing the computer has a significant impact on attitude and intention. Those people might have a strong tendency to judge that it is totally fine to use the company's computer as long as it does not harm others and using during non-business hours, instead of thinking that it is inappropriate to use the company's computer not for business intention.

• Journal of Trauma and Injury
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• v.21 no.2
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• pp.115-119
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• 2008

Purpose: Abrupt abstinence from alcohol in cause of chronic alcohol addiction can trigger alcohol withdrawal syndrome. The authors studied the effect of post-operative alcohol withdrawal syndrome in patients who require intensive care due to trauma. Methods: For the study group, we selected 70 patients who had undergone emergency surgery from May 2003 to March 2007 due to trauma and who had been treated with prophylactic thiamine. Data was collected retrospectively. We excluded those who extended their hospital stay for other than traumatic causes, those who died within 3 days of surgery after trauma, those who transferred to other institutions, and those who received a psychiatric diagnosis. Patient groups were determined by the existence or the non-existence of withdrawal syndrome. Age, sex, injury mechanism, mortality, complications, durations of hospital stay and intensive care, use of mechanical ventilator, and sedative use were investigated. A Chi-square test and The Mann-Whitney method were used for statistical analysis in this study. Results: Twenty-four (24) patients from the 58 who had an ISS of 16 or more showed alcohol withdrawal syndrome, and men were shown to be affected with the syndrome significantly more than women. Although ISS was higher in the group with alcohol withdrawal syndrome, statistically, the difference was not significant (P<0.08). The total hospital stay in the patient group with alcohol withdrawal syndrome was on average 10 days longer. However, the difference was not significant (P<0.054). The duration of intensive care in the patient group with alcohol withdrawal syndrome was significantly longer (P<0.029). The patients with alcohol withdrawal syndrome showed no significant difference in the duration of mechanical ventilator use (P<0.783), or in the duration of sedative use (P<0.284). Respiratory distress, pneumonia, upper airway infection, sepsis, acute renal failure, and mortality in the alcohol withdrawal syndrome group were investigated, but no statistically significant difference were noted. Conclusion: We found that the duration of intensive care in chronic alcohol abusers was longer due to the development of alcohol withdrawal syndrome. We also discovered that, when the patients overcame the symptoms of alcohol withdrawal syndrome after intensive care, no difference was found in the frequency of developing complications, the morbidity, and the mortality. Therefore, we conclude that intensive care in trauma patients who are chronic alcohol abusers decreases the incidence of complications found in patients with post-operative alcohol withdrawal syndrome and does not adversely impact the prognoses for those patients.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.44-45
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• 2010

We are currently conducting studies on culturing and biocompatibility assessment of various cells such as neural stem cells and induced pluripotent stem cells(IPS cells) on carbon nanotube (CNT), on nerve regeneration electrodes, and on silicon wafers with a focus on developing nerve integrated CNT based bio devices for interfacing with living organisms, in order to develop brain-machine interfaces (BMI). In addition, we are carried out the chemical modification of carbon nanotube (mainly SWCNTs)-based bio-nanosensors by the plasma ion irradiation (plasma activation) method, and provide a characteristic evaluation of a bio-nanosensor using bovine serum albumin (BSA)/anti-BSA binding and oligonucleotide hybridization. On the other hand, the researches in the case of "novel plasma" have been widely conducted in the fields of chemistry, solid physics, and nanomaterial science. From the above-mentioned background, we are conducting basic experiments on direct irradiation of body tissues and cells using a micro-spot atmospheric pressure plasma source. The device is a coaxial structure having a tungsten wire installed inside a glass capillary, and a grounded ring electrode wrapped on the outside. The conditions of plasma generation are as follows: applied voltage: 5-9 kV, frequency: 1-3 kHz, helium (He) gas flow: 1-1.5 L/min, and plasma irradiation time: 1-300 sec. The experiment was conducted by preparing a culture medium containing mouse fibroblasts (NIH3T3) on a culture dish. A culture dish irradiated with plasma was introduced into a $CO_2$-incubator. The small animals used in the experiment involving plasma irradiation into living tissue were rat, rabbit, and pick and are deeply anesthetized with the gas anesthesia. According to the dependency of cell numbers against the plasma irradiation time, when only He gas was flowed, the growth of cells was inhibited as the floatation of cells caused by gas agitation inside the culture was promoted. On the other hand, there was no floatation of cells and healthy growth was observed when plasma was irradiated. Furthermore, in an experiment testing the effects of plasma irradiation on rats that were artificially given burn wounds, no evidence of electric shock injuries was found in the irradiated areas. In fact, the observed evidence of healing and improvements of the burn wounds suggested the presence of healing effects due to the growth factors in the tissues. Therefore, it appears that the interaction due to ion/radicalcollisions causes a substantial effect on the proliferation of growth factors such as epidermal growth factor (EGF), nerve growth factor (NGF), and transforming growth factor (TGF) that are present in the cells.