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A study on post-formula instruction of Kyejitang(桂枝湯) (계지탕(桂枝湯) 방후주문(方後註文)에 관한 연구(硏究))

  • Kim, Kang;Meang, Woongjae
    • The Journal of Korean Medical History
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    • v.23 no.1
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    • pp.23-41
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    • 2010
  • Greater yang disease(太陽病) is a syndrome induced by peripheral obstruction. One of them is "wind stroke(中風)" with the obstruction in lymphatic system. The other obstruction appearing on circulatory system is called "cold damage(傷寒)." Kyejitang(桂枝湯) is the formula prescribed for greater yang wind stroke pattern(太陽中風證) which is caused by peripheral lymphatic duct obstruction. Ramulus Cinamoni acts as a vasodilator and Radix Paeoniae relieves the abdominal tension. They make blood move to the internal organ and this can remove the retention of peripheral lymphatic system. Covering the patient with a blanket and getting him/her to have hot and thin rice gruel causes slight Diaphoresis, contributing to relieving the retention of lymphatic system. Disharmony between nutrient and defense(營衛不和) means that pressure becomes different between lymphatic system and vascular system. Kyejitang(桂枝湯) is called releasing muscles formula(解肌劑) because it can resolve such pressure difference. Diaphoresis is not a means to eliminate pathogenic qi(邪氣) from the body. That is the syndrome proving that the body fluid has moved around when disordered fluid distribution is corrected. Therefore, diaphoresis should be induced weakly all the time. If diaphoresis is induced excessively, body fluid will move more than desired and then illness cannot be cured. In Sanghanlun(傷寒論), dispersing drugs aim at addressing the retention in the exterior field, but it actually applies to the entire exterior and interior to make body fluid move. Therefore, diaphoresis does not just act on exterior field, and freeing the stool does not only apply to interior field. Distribution of body fluid changed by pathogenic qi(邪氣) influences the whole body because the human body has a closed circulatory system. Sanghanlun(傷寒論) has included treatments for pathogenic disease. However, its value should not be limited to pathogenic disease. It is because controlling blood flow by sending body fluid to the place a doctor wants is certainly worth using for treatment of non-exogenous disease or chronic illnesses.

Study on the experimental single lung transplantation in the mongrel dogs(I) (한국산 잡견에서의 단일 폐 이식술에 관한 실험적 연구 (I))

  • 김주현
    • Journal of Chest Surgery
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    • v.24 no.6
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    • pp.533-540
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    • 1991
  • We have performed 14 single lung transplantation in mongrel dogs transplanting the left lung exclusively from December 1989 to January 1991, in the department of thoracic surgery of Seoul National University Hospital. In the donor dogs, the main pulmonary artery was divided proximal to its bifurcation, and the left atrium was incised freeing the left veins with a generous atrial cuff. We used cold saline in the first 7 transplantation[group I ] and a Euro Collins solution in the remaining 7 transplantations[group II ] as a lung preservatives. The bronchus was divided at two cartilage rings proximal to the upper lobe bronchus take off. In the recipient procedure, we used a Fogarty catheter as a bronchus block. Left atrial anastomosis was performed first using 5 - 0 prolene and the pulmonary artery was anastomosed using 6 - 0 prolene. The bronchus was anastomosed next with 4 - 0 Vicryl interruptly and covered with a greater omentum which had been prepared previously. In group I the three dogs died at eleven hours, 5 days, and 14 days, postoperatively and the remaining four doings were killed at 5 days, 5 days, 6 days, and 12 days, respectively. In group II the two dogs died during the operation, one dog died at 6 hours, two dogs died at 6 days postoperatively. Two dogs were killed at 5 days, and 7 days. No significant difference was noted between the two groups in survival time, lung infiltration of transplanted lungs, and perfusion defects in perfusion lung scans. Of the 8 dogs which died naturally, the causes of death were as follows: 2 cases of sepsis, 2 cases of ventricular fibrillations, 2 cases of malnutrition, and 2 cases of respiratory failures.

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Histologic Investigation on Canine Single Lung Transplantation (한국산 잡견에서의 단일 폐이식술후 조직학적 고찰)

  • 이정상
    • Journal of Chest Surgery
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    • v.25 no.3
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    • pp.220-231
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    • 1992
  • We have performed 28 single lung transplantation in mongrel dogs transplanting the left lung exclusively from November 1989 to September 1991, in the department of thoracic surgery of Seoul National University Hospital. In the donor dogs, the main pulmonary artery was divided proximal to its bifurcation, and the left atrium was incised freeing the left veins with a generous atrial cuff. We used cold saline in the first 7 transplantations and Euro-Collins or modified Euro-Collins solution in the remaining 17 transplantations as a lung preservatives. The bronchus was divided at two cartilage rings proximal to the upper lobe bronchus take off. In the recipient procedure, we used a Fogarty catheter as a bronchus block. Left atrial anastomosis was performed first using 5-O prolene and the pulmonary artery was anastomosed using 6-O prolene. The bronchus was anastomosed next with 4-O vicryl interruptedly and covered with a greater omentum which had been prepared previously. All dogs received cyclosporin A and azathioprine as immunosuppressants and were divided into two group. In the 10 Group I dogs, they survived within 6 days, mean survival time was 66.8$\pm$53.4 hours. In remainder 14 Group lI dogs, they survived above 6 days, mean survival time was 9. 5$\pm$5.6 days. The cause of death were as follows: 2 cases of sacrifice, 2 cases of respiratory insufficiency during operation, 2 cases of arrhythmia immediate postoperatively, 2 cases of bleeding, others in Group I, and 6 cases of sacrifice, 4 cases of sepsis, 3 cases of bleeding, others in Group lI. Results of bronchoscopic findings were obstruction above 50% in 12 cases of 16 performance cases within 5th day. Early chest radiologic haziness were showed, and total lung perfusion defect was frequently showed in both group within 7th day. Main autopsy findings were left atrial and pulmonary arterial thrombi and bronchial obstruction The major histologic findings of Group I were pleural exudate, hemorrhagic infarct, pulmonary congestion, and interesting histologic findings of Group II were 3 cases of perivascular or peribronchial lymphocyte infiltration, 3 cases of hemorrhage infarct, 2 cases of interstitial pneumonitis. The structual change of bronchioles, suggesting bronchiolitis obliterans was not observed due to improper preparation of proximal pulmonary tissue and short term survival times.

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A Study of Applied Digital Media in Street Environmental Design (가로환경디자인에 있어서 디지털미디어의 활용에 관한 연구)

  • Lee, Hyuk-Soo;Hong, Kwan-Seon
    • Archives of design research
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    • v.18 no.1 s.59
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    • pp.115-124
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    • 2005
  • Fast developing digital technology is Having an enormous societal influence, creating a porous new world without boundaries. This phenomenon applies to a whole range of fields, including culture, politics and even our daily lives. Urban Street cannot be excluded from this world-transforming change. Digital technology is changing the physical structure, growing patterns, function and role of the Urban Street. As a result, Urban Street should now be freeing themselves from the old-world functionalism, which has been pursued uniformly under the names of rationality and efficiency. We have, then, to think about the culture of the Digital Urban Street,'that is, the digital life style, which is tangibly generated in the concrete city space, and which must be prepared for further digitalization. This paper argues that the street must be understood as a communications centre, because digital technology has created a new communications style. Also, this paper focuses on how the physical environment of Urban Street will evolve with regard to both function and appearance. In conclusion, studying the ubiquitous space, it also looks at how existing urban planning and space design should lead to the further development of Urban Street using digital technology, as well as to the role this technology will have in the future.

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Correction of Persistent Enophthalmos after Surgical Repair of Blow Out Fracture Using Orbital Decompression Technique of Contralateral Eye (안와골파열골절 정복술 후 지속되는 안구함몰 환자에서 정상측 안구의 안구 감압술의 치험례)

  • Lee, Jun-Ho;Park, Won-Yong;Nam, Hyun-Jae;Kim, Yong-Ha
    • Archives of Craniofacial Surgery
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    • v.9 no.2
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    • pp.101-104
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    • 2008
  • Purpose: Diplopia and cosmetically unacceptable enophthalmos are the major complications of blow out fracture. Prolapse of orbital tissue into the sinuses, enlarged orbital volume, atrophy of orbital fat and loss of support of orbital walls play a role in the pathogenesis of enophthalmos. To correct post-traumatic enophthalmos, freeing of incarcerated orbital contents combined with reduction of bony orbital volume and reconstruction of suspensory support of globe is necessary. But remained enophthalmos after surgical treatment is difficult to correct completely. In this case, the authors performed implant insertion for affected orbit and endoscopic orbital decompression for unaffected orbit for correction of late enophthalmos. Method: We reviewed a girl patient with right inferomedial orbital wall blow out fracture, right zygoma fracture treated at our hospital for correction of enophthalmos. An 18-year-old female had sustained posttraumatic enopthalmos. Two surgical management was performed for correction blow out fracture at the other hospital. But residual diplopia, enophthalmos, cheek drooping were found. And then she transferred to our hospital. She had severe enophthalmos(5 mm) also had diplopia and extraocular muscle limitation. We performed operation for correction of enophthalmos. After operation, she showed minimal improvement of diplopia and enophthalmos(3 mm). The authors make plan for operation for correction enophthalmos due to cosmetical improvement. Implant insertion was performed for affected orbit. For unaffected orbit, nasoendoscopic medial orbital wall decompression was proceeded. Result: Correction of enophthalmos was found after operation and was maintained for nine years follow-up. Patient expressed satisfaction for the result. Conclusion: To correct persistant enophthalmos, we could have satisfactory result with orbital wall reconstruction on affected eye and decompression on unaffected eye.

Teaching Architectural Design in Post-War America - Gyorgy Kepes' Basic Course at MIT's Department of Architecture - (20세기 후반 MIT의 건축설계 교육과 기요르기 케피쉬의 기초디자인 프로그램의 특성과 변화에 관한 연구)

  • Pai, Hyung-Min
    • Journal of architectural history
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    • v.15 no.2
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    • pp.39-54
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    • 2006
  • Focusing on the emergence of the basic course in American schools of architecture, in particular Gyorgy Kepes' courses at MIT, this paper studies the transformation of architectural pedagogy during the years after World War II. Kepes centered his architectural pedagogy on the picture plane, which was to function as the primary media for applying the principles of Gestalt psychology, that is the identification of the whole and its parts and the reciprocity between the internal human organism and the outside world. Kepes hence introduced a set of unconventional visual practices that were not readily assimilated to architectural conventions. Paralleling the establishment of the basic course, MIT also formulated a functionalist and spatial pedagogy with its two initial design studios, courses 4.721 and 4.722. These studios shared the notion that architectural design evolved from the inside toward the outside, an idea that took hold not just in the pragmatic environment of MIT's studios but also in conservative academic programs as well as in popular magazines, picture books, and exhibitions for the consumer public. The architectural surface became inseparable from the objects of art, furniture, and design, all of which were to be the generators of space. Hence, during the 1950s, the architectural surface provided a specific locus of intersection between the visual fundamentals of the basic course and the working principles of architectural design. Kepes, however, had by this time become disillusioned with architecture's potential as the medium of unity. Though he maintained the Gestalt logic of identity, he expanded it toward the goal of grander synthesis of society and consciousness freeing himself from the constraints of disciplinary instruction. In the case of Kepes, the mediating role of the picture plane was foregone in a regressive turn toward a primal, innocent, and direct experience.

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STUDY ON FEMINITY AND THE IDEAL BEAUTY OF BODY IMPLIED IN THE FASHION AND THE ANTI-FASHION MOVEMENT IN THE VICTORIAN PERIOD (II) (빅토리아시대 유행복식과 반유행복식 운동에 나타난 여성성과 인체미에 관한 연구 (II))

  • 김정선;김민자
    • Journal of the Korean Society of Costume
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    • v.51 no.6
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    • pp.5-24
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    • 2001
  • This paper is intended to explore femininity the ideal beauty of body and the features in fashion pursued in the Fashion system and the Anti-Fashion Movement in the Victorian period, on which the modern fashion is based. For the informative facts needed in this paper, books on history, fashion history, feminism, art history of aestheticism and the ideal beauty of body are referred to. On the part Ⅱ of this paper, the femininity and the ideal beauty of body implied in the Aesthetic Movement and Rational Dress Movement as the anti-fashion movement in the Victorian period will be reviewed. Following are the conclusion : First, the works in Aesthetic Movement mainly include the image of sensual female. The essence of femininity is categorized by cultural value, poetic spirit. appetite for sex and self-expression. The ideal beauty of body pursued in this movement is the beauty of immatured body, which means rejection of maternity as well as appetite for sex in the form of metaphor of the power and enthusiasm of female. The features of Aesthetic Movement emphasize the image of sensual and characteristic woman. These features are expressed in the natural waist line and the vertical H silhouette of high waist, natural exposure of body by means of drapery, simplicity and decency by design without fixed forms and seemingly faded colors. Second, Rational Dress Movement attempted to evaluate the femininity in a different way and ultimately pursued masculinity. Therefore, morality, liberty, intelligence, spirituality, self-control, willingness, which had been believed to exclusively belong to male, are added to the categories of femininity. The ideal beauty of body is expressed in the form of Venus Coelestic which is refined and strong. This symbolizes woman's freeing from the fate of reproduction and subordinate relationship with male, morality, decision of one's own and willingness. The features of Rational Dress Movement represent the image of strong-willed and moral woman in its internal meaning. The features of its fashions represent the concealment of the body, emphasis on activeness in pants without decoration and simplicity in its external form. All these features resulted from the pursuit of masculinity.

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A Study on Tunnel Cleaning Automation Equipment & Introducing Advanced Tunnel Cleaning Automation Equipment (터널 청소장비의 고찰 및 개선된 모델에 관한 연구)

  • Lee, Tai-Sik;Jang, Kyung-Soo;Koo, Ja-Kyung;Park, Kyung-Soon
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2006.11a
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    • pp.669-673
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    • 2006
  • Field works are decreasing gradually since advancement of industrial robots. Tunnel cleaning is a dangerous field work which can be solved only by introducingadvanced tunnel cleaning automation equipment. Industrial robots work tirelessly night and day without a loss in performance. Consequently, greatly reduce the costs of manufactured goods.So far only 200 construction robots are invented. Robots used for tunnel cleaning are not of high standard they always need additional workers for job to be done. Robots offer specific benefits to workers, industries and countries. If introduced correctly for tunnel cleaning, industrial robots can improve the quality of life by freeing workers from dirty, boring, dangerous and heavy labor. Development of advanced tunnel cleaning automation equipment is a must to overcome above issues. The benefits of robots to industry include improved management control, productivity and consistently high quality products. This research is a study on tunnel cleaning automation equipment and introducing advanced tunnel cleaning automation equipment.

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Digital Culture and the Utility of Poetry in a Convergence Age (융복합시대에 디지털문화와 시의 효용성 연구)

  • Seo, Hae Ryen;Kim, Kyoung Soon
    • Journal of Digital Convergence
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    • v.16 no.1
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    • pp.343-350
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    • 2018
  • The purpose of this paper is to explore the characteristics of a digital culture, its negative effects, especially automatism of perception, a poetic strategy against automatism of perception and the utility of poetry including the therapeutic function of poetry. The new technologies offer us various experience, great opportunities and rosy future by freeing us from boring and laborious tasks, and difficult decisions. Through the excessive and habitual use of new technologies, we may become too dependent on machines, losing our thinking abilities, sensibility, perception and creativity. Therefore, we need poetry to recover the sensation of life and make us feel things. Reading poetry allows us to look into someone else's soul and cultivate the ability to empathize. As a healing fountain, poetry leads us to a way for a change of heart, a recovery of psychic health and universal love through perfect communion in ourselves and in society. Furthermore we need a systematic and in-depth study of digital poetry as well as traditional poetry.

Regulations of Reversal of Senescence by PKC Isozymes in Response to 12-O-Tetradecanoylphorbol-13-Acetate via Nuclear Translocation of pErk1/2

  • Lee, Yun Yeong;Ryu, Min Sook;Kim, Hong Seok;Suganuma, Masami;Song, Kye Yong;Lim, In Kyoung
    • Molecules and Cells
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    • v.39 no.3
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    • pp.266-279
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    • 2016
  • The mechanism by which 12-O-tetradecanoylphorbol-13-acetate (TPA) bypasses cellular senescence was investigated using human diploid fibroblast (HDF) cell replicative senescence as a model. Upon TPA treatment, protein kinase C (PKC) ${\alpha}$ and $PKC{\beta}1$ exerted differential effects on the nuclear translocation of cytoplasmic pErk1/2, a protein which maintains senescence. $PKC{\alpha}$ accompanied pErk1/2 to the nucleus after freeing it from $PEA-15pS^{104}$ via $PKC{\beta}1$ and then was rapidly ubiquitinated and degraded within the nucleus. Mitogen-activated protein kinase docking motif and kinase activity of $PKC{\alpha}$ were both required for pErk1/2 transport to the nucleus. Repetitive exposure of mouse skin to TPA downregulated $PKC{\alpha}$ expression and increased epidermal and hair follicle cell proliferation. Thus, $PKC{\alpha}$ downregulation is accompanied by in vivo cell proliferation, as evidenced in 7, 12-dimethylbenz(a)anthracene (DMBA)-TPA-mediated carcinogenesis. The ability of TPA to reverse senescence was further demonstrated in old HDF cells using RNA-sequencing analyses in which TPA-induced nuclear $PKC{\alpha}$ degradation freed nuclear pErk1/2 to induce cell proliferation and facilitated the recovery of mitochondrial energy metabolism. Our data indicate that TPA-induced senescence reversal and carcinogenesis promotion share the same molecular pathway. Loss of $PKC{\alpha}$ expression following TPA treatment reduces pErk1/2-activated SP1 biding to the $p21^{WAF1}$ gene promoter, thus preventing senescence onset and overcoming G1/S cell cycle arrest in senescent cells.