• 제목/요약/키워드: free-year system

검색결과 199건 처리시간 0.028초

Adjuvant Chemotherapy with or without Concurrent Radiotherapy for Patients with Stage IB Gastric Cancer: a Subgroup Analysis of the Adjuvant Chemoradiotherapy in Stomach Tumors (ARTIST) Phase III Trial

  • Kim, Youjin;Kim, Kyoung-Mee;Choi, Min Gew;Lee, Jun Ho;Sohn, Tae Sung;Bae, Jae Moon;Kim, Sung;Lee, Su Jin;Kim, Seung Tae;Lee, Jeeyun;Park, Joon Oh;Park, Young Suk;Lim, Ho Yeong;Kang, Won Ki;Park, Se Hoon
    • Journal of Gastric Cancer
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    • 제18권4호
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    • pp.348-355
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    • 2018
  • Purpose: We aimed to discuss the roles of radiation and chemotherapy as adjuvant treatment in patients with staged IB GC who were enrolled in the adjuvant chemoradiotherapy in stomach tumors (ARTIST) trial. Materials and Methods: Among the 458 patients who were enrolled in the ARTIST trial, 99 had stage IB disease. The patients were randomly assigned to receive either adjuvant chemoradiotherapy with capecitabine plus cisplatin (XP, n=50) or chemoradiotherapy (XPRT, n=49). Survival analyses were performed in accordance with the AJCC 2010 staging system. Results: According to the AJCC 2010 system, stage migration from IB to II occurred in 71% of the patients; 98% of the T2 N0 cases were reclassified as T3 N0, and 42% of the T1 N1 cases were reclassified as T1 N2. When comparing survival outcomes between the XPRT and XP arms for stage IB cancer (AJCC 2002), no significant difference in 5-year disease-free survival (DFS) between the 2 arms was found. (median 5-year DFS, not reached, P=0.256). The patients classified as having stage IB cancer (AJCC 2002) and reclassified as having stage II cancer (AJCC 2010) exhibited worse prognoses than those who remained in stage IB, although the difference was not statistically significant (5-year DFS rate, 83% vs. 93%). When we compared 5-year DFS in 70 patients with stage II (AJCC 2010), the addition of radiotherapy to XP chemotherapy did not show better outcome than XP alone (P=0.137). Conclusions: The role of adjuvant chemoradiotherapy in the treatment of stage IB GC (AJCC 2002) warrants further investigation.

뇌기반 교육원리를 적용한 가정과 공감교육 프로그램 개발 (Development of Empathy Education Program Using Brain-Based Education Principles in Home Economics)

  • 이은진;최새은
    • 한국가정과교육학회지
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    • 제33권2호
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    • pp.153-172
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    • 2021
  • 본 연구는 가정과교육에서의 뇌기반 교육원리를 적용한 공감교육 프로그램 개발을 목적으로 한다. 이를 위하여 ADDE(Analysis, Design, Development, Evaluation)의 절차에 따라 공감 및 뇌과학에 관련된 문헌 분석과 2015 개정 기술·가정 교육과정 및 교과서 3종을 분석하여 중학생 대상 가정과 공감교육 프로그램을 개발하고 전문가 평가를 실시하였다. 연구 결과 가정과교육에서의 공감교육을 위한 뇌기반 교육원리는 '모방을 통한 이해', '상상을 통한 추론', '경험을 통한 상호작용', '실천을 통한 내면화'라는 네 가지로 도출된다. 2015 개정 기술·가정 교육과정 및 교과서 분석 결과, 공감은 가정과의 교과역량인 관계형성능력을 기르는 요소로서 '자신', '타인', '공동체'에서의 관계 차원에서 공감 관련 내용요소들이 다루어졌다. 개발된 프로그램의 전문가 타당도 평가를 분석한 결과 전체 항목의 타당도 평균이 4.88, 타당도 지수(CVI)는 0.98로 프로그램이 타당한 것으로 나타났다. 본 연구를 통해 가정과교육에서의 공감교육의 가능성을 확인할 수 있었고, 현재 가정과교육에서는 뇌과학을 고려한 연구는 미흡한 실정인데 본 연구는 가정과교육에서의 공감교육을 '뇌과학'과 접목하여 새롭게 제시하였다는 점에서 의의가 있다.

유아교육 (The Early Childhood Education in Korea)

  • 최석란;김영숙
    • 아동학회지
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    • 제30권6호
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    • pp.209-221
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    • 2009
  • The early childhood education in Korea has made a great progress during the last thirty years. However, understanding the early childhood education is a challenging task because of the diversity of the fields. Currently 38% of 3-5 year old children are enrolled in kindergarten. And several efforts to develop and distribute the standard curricula on a national level were underwent successfully. Researches are rapidly expanding in volume and the topics are becoming diverse. Focuses of researches moved from the area of cognitive development, science and mathematics in 80s, social and emotional aspects in 90s to language, curriculum and teacher education in 2000s. One of the emerging issues is the inclusion of kindergarten to public education system and free kindergarten education for young children. The second issues is more interdisciplinary policies are in need related to the low-birth rate in nation. The third one is about teacher training policy. The fourth one is related to the health, nutrition and safety of young children. And the fifth issue is moving educational system and policies that provide better future of young children while focusing on the children in low income families and children with absolute poverty.

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SF6 분해 및 무해화 시스템의 개념 설계 및 운영 결과 (Conceptual Design and Operation Results for SF6 Decomposition and Pollution Control System )

  • 이중원;김미영;안지호;변영환
    • KEPCO Journal on Electric Power and Energy
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    • 제8권2호
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    • pp.111-118
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    • 2022
  • SF6 is used as an insulating gas because of its excellent electrical insulation properties, non-toxicity, and non-inflammability. On the other hand, the global warming potential of SF6 is 23,900 times higher than that of CO2. The Korea electric power cooperation (KEPCO) is responsible for 80% of the domestic SF6 usage, and approximately 6,000 tons are currently charged in electrical and power facilities. KEPCO will gradually replace the insulating gas with SF6-free gas from 2023. SF6 decomposition facilities are required because more than 60 tons of SF6 will need to be disposed of annually from existing equipment. This study developed a novel decomposition and pollution control system that can process 60 tons of SF6 per year. This facility can decompose more than 97.7% of SF6, with the emissions of hazardous and toxic materials below the legal limit.

KISTI-ACOMS를 기반으로 한 한국작물학회 온라인논문투고관리시스템 개발 및 개선 방안 (Development and Improvement of the Online Article Contribution Management System Based on KISTI-ACOMS for the Korean Society of Crop Science)

  • 박재원;강무영;윤화묵
    • 한국작물학회지
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    • 제49권6호
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    • pp.552-562
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    • 2004
  • KISTI는 학회업무 및 학술정보 관리를 학회가 어려움 없이 처리하도록 지원하고자, 학회 학술정보 유통체제 전 과정을 온라인 화하고 쉽게 관리할 수 있도록 한 ${\ulcorner}$KITTI­ACOMS (KISTI-Article COntribution Management System: KISTI-학회논문투고관리시스템)${\lrcorner}$을 개발하여 2001년부터 학회에 무상으로 보급하여 왔다. 최근 KISTI-ACOMS를 이용하고자 하는 학회의 요청이 더욱 확대되고 있어, KISTI는 많은 학회의 특성들을 의견수렴 하여, KISTI-ACOMS의 표준화를 목표로 보완해 나가고 있다. 본 연구논문의 구성은 다음과 같다. 1. KISTI-ACOMS 개요 설명. 2. KISTI-ACOMS를 기반으로 구축한 한국작물학회의 학회 논문투고관리시스템의 모듈별 기능 및 사용자 접근 권한에 따른 논문투고 심사 단계별 처리 방법 기술. 3. 향후 시스템에 필요한 기능 및 명세를 기술함으로써 한국작물학회 뿐만 아니라 KISTI-ACOMS를 기반으로 한 개선 된 온라인논문투고관리시스템을 제시.

KISTI-ACOMS를 기반으로 한 한국환경생태학회 온라인논문투고관리시스템 개발 및 개선방안 (A Study on the Development and Improvement of the Online Article Contribution Management System Based on KISTI-ACOMS for Korean Society of Environment and Ecology)

  • 박재원;최선희;강무영
    • 한국환경생태학회지
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    • 제18권4호
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    • pp.456-464
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    • 2004
  • KISTI(한국과학기술정보연구원)는 학회 업무 관리, 학술정보 관리를 학회가 어려움 없이 처리하도록 지원하고자, 학회 정보화 사업의 일환으로 학회 학술정보 유통체제 전 과정을 온라인화하고 쉽게 관리할 수 있도록 한 $\boxDr$KISTI-ACOMS(KISTI-Article COntribution Management System: KISTI-학회논문투고관리시스템)$\boxUl$을 개발하여 2001년부터 학회에 무상으로 보급하여 왔다. 최근 KISTI-ACOMS를 이용하고자 하는 학회의 요청이 더욱 확대되고 있어, KISTI는 많은 학회의 특성들을 의견수렴하여, KISTI-ACOMS의 표준화를 목표로 보완해 나가고 있다. 본 연구는 KISTI-ACOMS를 기반으로 구축한 한국환경생태학회의 학회논문투고관리시스템의 기능에 대해 살펴보고, 향후 시스템에 필요한 기능 및 명세를 기술함으로써 한국환경생태학회의 개선된 온라인논문투고관리시스템을 제시한다.

Proposal of a New TNM Classification for Gastric Cancer: Focusing on pN3b and Cytology-Positive (CY1) Disease

  • Kim, Sa-Hong;Lee, Hyuk-Joon;Park, Ji-Hyeon;Choi, Jong-Ho;Park, Shin-Hoo;Choe, Hwi-Nyeong;Oh, Seung-Young;Suh, Yun-Suhk;Kong, Seong-Ho;Park, Do-Joong;Yang, Han-Kwang
    • Journal of Gastric Cancer
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    • 제19권3호
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    • pp.329-343
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    • 2019
  • Purpose: Gastric cancer with lymph node metastasis (LNM) more than 15 (N3b) was defined as stage IV until the 6th AJCC system. However, it has been reclassified as a localized disease (stage IIb or III) since the 7th system. The aim of this study is to demonstrate that the survival of N3b is comparable to cytology-only positive (CY1-only) stage IV and to propose a new TNM system interpreting N3b as an eligibility criterion for receiving more intensive chemotherapy regimens. Materials and Methods: 1,430 patients who underwent gastric cancer surgery at Seoul National University Hospital from 2007 to 2012 were retrospectively analyzed. The 5-year survival rate (5YSR) and 3-year recurrence-free survival (RFS) were evaluated according to the 7th and 8th systems, as well as a new categorization based on N-classification; N0-2 (LNM<7), N3a (LNM 7-15), or N3b (LNM>15). Results: The survival of N3b is comparable to that of CY1-only stage IV (log rank test, P=0.671) and is distinct from that of grossly stage IV (log rank test, P<0.001). The survival of the remaining stage IIIc (T4bN3a) was comparable to those of N3b and CY1-only stage IV. Most N3b patients had significantly shorter 3-year RFS and mean RFS than those with IIb-IIIc, as if N3b itself was a higher TNM stage. Conclusions: In terms of survival, T4bN3a, N3b, and CY1-only stage IV were unified as stage IVa, while grossly stage IV was defined as stage IVb. N3b can be regarded as an eligibility criterion for undergoing more intensive chemotherapy regimens.

출산조절정책의 현황과 전망 (Current Status and Future Prospects of the Population Control Policy in Korea)

  • 조남훈
    • 한국인구학
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    • 제11권1호
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    • pp.14-31
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    • 1988
  • The national family planning program in Korea, which was instituted as an integral part of the nation's economic development plans since 1962, has contributed greatly to a reduction in the fertility and population growth rate. The total fertility rate dipped from 6.0 births per women in 1960 to 2.0 in 1985, and the population growth rate rom 2.84 percent per year to 1.25 percent during the same period, while the contraceptive practice rate for the 15-44 married women increased from 9 percent in 1965 to 70 percent in 1985. Study findings indicate that the fertility reduction in the past 26 years is largely attributed to the virgorous implementation of the national family planning program, rising age at marriage, wide-spread use of induced abortion, and the changes in attitude regarding the value of children that came into being in the wake of the rapid socio-economic development over the period. Among the strengths of the national family planning program are the following : 1) a pluralistic system of program manageent with active participation of various government and voluntary organizations, 2) utilization of a large corps of family planning field workers to conduct face-to-face communication and motivation activities, 3) use of private physicians with government support to provide contraceptive services, 4) a systematic program management system including program planning of traget allocation, evaluation, and supervision with a broad MIS and award system, 5) numerous incentive and disincentive schemes for stimulating the small family norm and contraceptive use, and 6) strong commitments to the family planning program by political leaders. The new demographic targets during the Sixth Five-Year Economic and Social Development plan period(1987-91) have been set for a further reduction in the population growth rate to 1.0 percent by 1993, assuming that the TFR will decline to 1.75 level in 1995. This target is, however, not easy to achieve due to anticipated unfavorable factors like the strong boy preference, high discontinuation rates of reversible contraceptive methods, fertility termination-oriented contraceptive use, a plateau level of contraceptive practice rate that has mostly accounted for a sterilization, shortened length of birth intervals, and the changing patterns of contraceptive mix. The recent changes in contraceptive and fertility behaviors clearly indicate that the past quantity-oriented management system of the national program should be redirected toward a quality-oriented approach. Particularly, program efforts should be expanded to recruit new contraceptive users in the 20s of younger age groups, both for birth spacing and controlling their fertility since the women aged 20 to 29 account for more than 80 percent of the total annual births in recent years. In addition, the current contraceptive fee system of the national family planning program should be gradually shifted from free contraceptive services to a acceptor's charge system, and the provision of contraceptive services through the medical insurance system, which will cover the entire population by 1989, should be accelerated as a means of integration of family planning program with other health programs.

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Vertebral compression fractures after spine irradiation using conventional fractionation in patients with metastatic colorectal cancer

  • Rhee, Woo Joong;Kim, Kyung Hwan;Chang, Jee Suk;Kim, Hyun Ju;Choi, Seohee;Koom, Woong Sub
    • Radiation Oncology Journal
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    • 제32권4호
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    • pp.221-230
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    • 2014
  • Purpose: To evaluate the risk of vertebral compression fracture (VCF) after conventional radiotherapy (RT) for colorectal cancer (CRC) with spine metastasis and to identify risk factors for VCF in metastatic and non-metastatic irradiated spines. Materials and Methods: We retrospectively reviewed 68 spinal segments in 16 patients who received conventional RT between 2009 and 2012. Fracture was defined as a newly developed VCF or progression of an existing fracture. The target volume included all metastatic spinal segments and one additional non-metastatic vertebra adjacent to the tumor-involved spines. Results: The median follow-up was 7.8 months. Among all 68 spinal segments, there were six fracture events (8.8%) including three new VCFs and three fracture progressions. Observed VCF rates in vertebral segments with prior irradiation or pre-existing compression fracture were 30.0% and 75.0% respectively, compared with 5.2% and 4.7% for segments without prior irradiation or pre-existing compression fracture, respectively (both p < 0.05). The 1-year fracture-free probability was 87.8% (95% CI, 78.2-97.4). On multivariate analysis, prior irradiation (HR, 7.30; 95% CI, 1.31-40.86) and pre-existing compression fracture (HR, 18.45; 95% CI, 3.42-99.52) were independent risk factors for VCF. Conclusion: The incidence of VCF following conventional RT to the spine is not particularly high, regardless of metastatic tumor involvement. Spines that received irradiation and/or have pre-existing compression fracture before RT have an increased risk of VCF and require close observation.

구주연합의 항공기 배출 규제 조치의 국제법적 고찰 (Legal Review on the Regulatory Measures of the European Union on Aircraft Emission)

  • 박원화
    • 항공우주정책ㆍ법학회지
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    • 제25권1호
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    • pp.3-26
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    • 2010
  • 환경 문제에 있어서 세계의 리더로서 앞 서 가는 구주연합(EU)은 2012년 1월 1일부터 EU 역.내외 항공기를 막론하고 EU 회원국 영토를 출발하고 도착하는 모든 항공기 운항자에 대하여 이들 항공기 엔진에서 배출되는 이산화탄소의 배출량을 규제하는 법 Directive 2008/101/EC를 2008년 제정, 공포하였다. 이에 따라 대한항공과 아시아나를 포함하여 EU를 운항하는 많은 EU 역외 항공사들은 지난 2004-2006년 3년간 연 평균 배출량의 97%만을 2012년 배출하고 2013년부터는 95%만을 배출 허용 받으며 부족한 배출량은 배출권 거래 시장에서 구입하여 충당하여야 한다. 상기 EU 조치는 다음과 같은 법적 문제를 야기한다. 첫째, EU의 법은 범 세계적 환경조약인 교토의정서가 선진국 그룹인 기후변화협약의 Annex I 국가에게만 이산화탄소 등 지구온난화가스 배출을 감축토록 한 것에 반한다. 교토의정서 제2조 2항은 지구온난화가스 감축에 있어서 항공기 배출에 관련한 체제를 ICAO를 통하여 해결하도록 위임하였는데 지역 기구인 EU가 이를 자체 지역에만 적용하기 위하여 작성한 것도 문제이다. 둘째, 역외 항공사들이 EU로 운항하는 데에 있어서 공해와 제3국의 상공을 비행하는데 EU 역내 비행에서 이루어지지 않는 여사한 비행 중 발생하는 배출을 어떤 근거로 EU가 규제할 수 있는가이다. 셋째, EU 회원국들이 Annex I 국가로서 교토의정서 상 항공기의 국내운항 배출에 대하여서는 2012년까지 이미 배출 감축의무를 지고 있음을 감안할 때, 2012년부터 시행되는 항공기 배출 감축 조치에 non-Annex I 국가의 항공 운항자를 끌어들이면서 EU 항공사들이 적어도 2012년에는 예상치 않은 이득을 얻는다는 문제도 발생한다. 과거 유사한 EU 주도의 환경관련 국제 분쟁을 살펴본 후, 상기 EU 조치를 국제법적으로 조명하고 결론에서 EU의 조치에 대한 국내적 대처를 간략기술하였다.

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