• 한국식품영양과학회지
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• 제31권1호
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• pp.109-116
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• 2002

본 연구는 김치와 노화 억제에 미치는 영향을 살펴보기 위하여 AIN-76 마우스 식이에 배추, 갓김치, 갓배추김치를 각동결건조 김치를 5%씩 첨가하여 만든 후 김치식이를 노화촉진쥐인 SAMP8에게 1년간 섭취시키면서 간의 노화관련 특성인 유리기 농도와 항산화효소계의 효소활성 변화를 살펴보았다. 노화촉진쥐 간의 총유리기, OH radical, $H_2O$$_2$그리고 TBARS 모두 가려에 따라 증가되었으며, 간에서 생성된 유리기 농도와 TBARS 농도는 대조군에 비해 김치섭취시 유의적으로 감소되었다(p<0.05). 그러나 생성된 유리기를 제거하기 위한 SOD 활성은 오히려 김치섭취군에서 유의적으로 증가되었으며(P<0.05), catalase와 GSH-px, GSH/GSSG의 비율도 김치섭취군에서 유의적으로 증가하였다(p<0.05). 따라서 김치섭취는 노화에 따라 발생되는 간의 유리기 및 TB-ARS 생성은 억제시키면서, 이를 제거하는 항산화계 효소는 활성화시켜 노화를 억제한 것으로 생각된다. 김치종류 중에서는 배추김치보다 배추갓김치와 갓김치가 유리기 생성 억제 및 항상화 효소 활성을 더욱 증진시킨 것으로 관찰되어 이는 첨가된 갓의 항산화물질 때문인 것으로 생각된다.

• Journal of Nutrition and Health
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• 제30권10호
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• pp.1132-1139
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• 1997

The effect of dietary taurine supplementation on plasma and hepatic lipid concentrations were evaluated in rats fed one of the following two cholesterol-free diets for 5 weeks ; a control diet(CD : cholesterol -free and taurine -fee diet) and a taurine supplemented diet(TSD : CD + 1.5% taurine). There were no significant differences in liver weight and cummulative body weight gains between the groups at the end of the experimental period .However, the liver weight to body weight ratio was significantly decreased (p<0.05) by dietary taurine supplementation. Plasma concentrations of total cholesterol , LDL-cholesterol and triglyceride were significantly reduced(37%, 26% and 53% respectively) in rats fed TSD compared to those fed CD. There were no significant differences in plasma free fatty acid and total phospolipid levels between the two groups. Feeding TSD to the rats significantly reduced their hepatic triglyceride concentration(43% decrease , p<0.001) but elevated their hepatic free fatty acid level(77% increase, p<0.001) as compared to the control rats. Liver cholesterol concentration was not significantly influenced by the dietary taurine supplementation. Dietary taurine supplementation significantly reduced the percentage of phosphatidylcholine and phosp-atidylethanolamine, but elevated the prospholipids in the liver homogenates as compared to the values for the CD rats. These results suggest the possible roles of taurine as a hypochlesterolmic and hypotriglyceride agent in rats fed a cholesterol-free diets.

• 한국식품영양과학회지
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• 제1권1호
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• pp.37-50
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• 1972

An analysis of the free amino acid contained in the plasma and erythrocytes of the six groups of Wistar Strain male adult rats(body weight 200-300g) having fasted for sixteen hours was made by means of the HITACHI Amino Acid Autoanalyzer and the result of which was corrected with RC-24 B TOMY Micro Hematocrit Centrifuge. There was a depression of the plasma and erythrocytes free amino acid level on the noprotein diet with ad libitum feeding. But on the 20% casein diet there was an elevation in the levels of free amino acid and consequently alanine, glysine, lysine, serine and arginine level in the erythrocytes and threonine glutamic acid and taurine level in the plasma increased on the high protein diet. There was more plasma and erythrocytes free amino acid level on the 5% casein-30% fat diet than on the 5% casein-no fat diet with pair-feeding. In comparison, on the low calorie diet more free amino acids were found in plasma than in erythrocytes, but on the higher calorie diet more free amino acids were found in the erythrocytes than in the plasma. On the 20% casein-30% fat diet with pair-feeding the erythrocytes free amino acids level increased but in plasma free amino acids level decreased. Such as an opposite result was given in plasma and erythrocytes free amino acids level. In the pair-fed four groups, erythrocytes per plasma generally increased in the rate of less than 10.0 as the calorie increased. The essential amino acid per non essential amino acid generally increased in the ratio as protein level and calorie increased, and that ratio range was from 0.2 to 0.7. And essential amino acid per non essential amino acid of plasma was higher than that of erythrocytes.

• 대한화학회지
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• 제15권2호
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• pp.69-84
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• 1971

An analysis of the free amino acid contained in the plasma and erythrocytes of the six groups of Wistar Strain male adult rats (body weight 200-300g) having fasted for sixteen hours was made by means of the HITACHI Amino Acid Autoanalyzer and the result of which was corrected with RC-24B TOMY Micro Hematocrit Centrifuge. There was a depression of the plasma and erythrocytes free amino acid level on the no-protein diet with ad libitum feeding. But on the 20% casein diet there was an elevation in the levels of free amino acid and consequently alanine, glysine, lysine, serine and arginine level in the erythrocytes and threonine, glutamic acid and taurine level in the plasma increased on the high protein diet. There was more plasma and erythrocytes free amino acid level on the 5% casein- 30% fat diet than on the 5% casein-no fat diet with pair-feeding. In comparison, on the low calorie diet more free amino acids were found in plasma than in erythrocytes, but on the higher calorie diet more free amino acids were found in the erythrocytes than in the plasma. On the 20% casein-30% fat diet with pair-feeding the erythrocytes free amino acids level increased but in plasma free amino acids level decreased. Such as an opposite result was given in plasma and erythrocytes free amino acids level. In the pair-fed four groups, erythrocytes per plasma generally increased in the rate of less than 10.0 as the calorie increased. The essential amino acid per non essential amino acid generally increased in the ratio as protein level and calorie increased, and that ratio range was from 0.2 to 0.7. And essential amino acid per non essential amino acid of plasma was higher than that of erythrocytes.

• 대한수학회지
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• 제41권5호
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• pp.913-920
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• 2004

We give a characterization for fundamental groups of graphs of groups amalgamating cyclic edge subgroups to be cyclic subgroup separable if each pair of edge subgroups has a non-trivial intersection. We show that fundamental groups of graphs of abelian groups amalgamating cyclic edge subgroups are cyclic subgroup separable, hence residually finite, if each edge subgroup is isolated in its containing vertex group.

• 한국수정란이식학회지
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• 제29권3호
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• pp.229-234
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• 2014

The aim of the present study was to compare two different serum-free media, modified synthetic oviduct fluid (mSOF) and modified potassium simplex optimization medium (mKSOM) containing 20% RD (RPMI1640 + DMEM, 1:1 v/v) (RD-mKSOM), for in vitro culture (IVC) of bovine embryos. After in vitro maturation and fertilization, the presumptive zygotes were cultured in two different serum-free conditions for 7 days and 9 days to evaluate blastocyst formation and hatching, respectively. Serum supplemented conventional CR2 medium was used as control. After 7 day of culture, there was no significant difference in cleavage and blastocyst formation rates among three groups (mSOF, 59.3 and 30.1%; RD-mKSOM, 65.0 and 41.5%; control, 51.6 and 38.0%, respectively). Hatching rate was significantly higher in control (69.0%) than other experimental groups (mSOF, 22.0%; RD-mKSOM, 39.5%) (P<0.0001 and P<0.001, respectively). Although both serum-free conditions showed lower hatching rates than serum-added control, in serum-free groups, RD-mKSOM showed significantly higher hatching rate than mSOF (P<0.001). In addition, one-step using RD-mKSOM may facilitate IVC procedure than two-step culture system. In conclusion, the results indicate that one-step RD-mKSOM is more suitable defined culture system for IVC of bovine embryos than two-step mSOF.

• Journal of Nutrition and Health
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• 제34권7호
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• pp.734-740
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• 2001

The purpose of this study was to investigate the effect of green tea catechins on the antioxidative defense enzyme activity of kidney in diabetic rats. Sprague-Dawley male rats weighting 100$\pm$10g were randomly assigned to one normal and three STZ-induced diabetic groups; catechin free diet(DM-0C group), 0.25% catechin diet(DM-0.25C group) and 0.5% catechin diet(DM-0.5C group). Diabetes was induced by intravenous of 55mg/Kg body weight of STZ in sodium citrate buffer(pH 4.3) after 4 weeks feeding of experimental diets. Rats were sacrified at the 6th day of diabetic states. Superoxide dismutase(SOD) activity in kidney was decreased by 25% and 20% in DM-0C and DM-0.25C groups compared with normal group, DM-0.5C group was not significantly different when compared with normal group. Glutathione peroxidase(GSHpx) activity in kidney was were no significant differences the diabetic groups compared to normal group. Xanthin oxidase(XOD) activity was increased by 110% and 63% in DM-0C and DM-0.25C groups compared with normal group, DM-0.5C group was not significantly different when compared with normal group. The contents of superoxide radical(O$_2$)in kindney were 116% and 33%, respectively, higher in DM-0C and DM-0.25C groups than normal group. DM-0.5C group and normal groups were similar levels in their superoxide radical contents of kidneys. Levels of TBARS(thiobarbituric acid reactive substance) in kidney were increased by 62% in DM-0C group, when compared with normal group, but those of DM-0.5C group were similar to that of normal groups. These results indicate that free radical generation system was weakened and free radical scavenger system was enhance in kidney of STZ-induced diabetics rats by dietary catechin. Thereby it may reduce renal disorders such as oxidative damage and aging of tissue.

• 대한통합의학회지
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• 제12권2호
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• pp.141-153
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• 2024

Purpose : This study aimed to determine the effects of a 12-week program of beta-glucan intake and muscle strengthening exercises on the body composition, physical fitness, blood lipids, insulin and insulin resistance of adult women. Methods : For this study, 45 adult women were selected and divided into two groups : the experimental group (n= 25), which received a combination of beta-glucan and strength exercise, and the control group (n= 20), which received only strength exercise. The program was conducted for 50 minutes three times a week for 12 weeks. Results : Several significant differences were found in both groups pre-to post program. First, in both groups, there were significant differences in hip circumferences (p<.05). Second, the results showed significant improvements in left grip strength and sit-ups achieved (p<.05), right grip strength (p<.001). Third although the results show no significant post-program differences in either group, there was a significant pre-to post-program difference in free fatty acids in both groups (p<.05). Fourth, the results show no significant differences in insulin or insulin resistance in either group, nor do they show any significant differences between the groups. Conclusion : The above results indicate that both groups exhibited decreased hip circumference and increased muscle strength (left grip strength) and muscle endurance. Furthermore, they indicate that when the beta-glucan intake and exercises were combined, the effects were more pronounced. Finally, because both groups exhibited significant increases in fat-free mass, muscle mass, skeletal muscle mass, muscle strength (right grip strength), and coordination as well as decreases in free fatty acids, it can be concluded that both the combined program of beta-glucan intake and exercise and a program of exercise alone can positively affect these outcomes.

• Kyungpook Mathematical Journal
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• 제56권3호
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• pp.927-938
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• 2016

In this note, we study a monodromy map of a fibered 2-bridge knot. We show the monodromy map of a fibered 2-bridge knot as an element in the automorphism group of a free group.

• 대한수학회논문집
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• 제22권2호
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• pp.157-161
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• 2007

Let G be a p-mixed abelian group with semi-complete torsion subgroup $G_t$ such that G is splitting or is of torsion-free rank one, and let R be a commutative unitary ring of prime characteristic p. It is proved that the group algebras RG and RH are R-isomorphic for any group H if and only if G and H are isomorphic. This isomorphism relationship extends our earlier results in (Southeast Asian Bull. Math., 2002), (Proc. Amer. Math. Soc., 2002) and (Bull. Korean Math. Soc., 2005) as well as completely settles a problem posed by W. May in (Proc. Amer. Math. Soc., 1979).