• Bioinformatics and Biosystems
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• v.2 no.2
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• pp.71-74
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• 2007

Cell phenotypes are determined by groups of functionally related genes. Microarray profiling of gene expression provides us response of cellular state to its perturbation. Several methods for uncovering a cellular network show reliable network reconstruction. In this study, we present reconstruction of genetic regulatory network of inflammation bowel disease in human peripheral blood mononuclear cell. The microarray based on Affymetrix Gene Chip Human Genome U133 Array Set HG-U133A is processed and applied network reconstruction algorithm, ARACNe. As a result, we will show that inferred network composed of 450 nodes and 2017 edges is roughly scale-free network and hierarchical organization. The major hub, CCNL2 (cyclin A2), in inferred network is shown to be associated with inflammatory function as well as apoptotic function.

• Journal of Welding and Joining
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• v.19 no.3
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• pp.267-273
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• 2001

In this study, welding phenomena involved in formation of penetrators during high frequency electric resistance welding were investigated. High speed cinematography of the process revealer that a molten bridge between neighboring skelp edges forms at apex point and travels along narrow gap toward to welding point at a speed ranging from 100 to 400 m/min. The bridge while moving along the narrow gap swept away oxide containing molten metal from the gap, providing oxide-free surface for a forge-welding at upsetting stand frequency of the budge formation, travel distance and speed of the bridge were affected by the heat input rate into strip. The travel distance and its standard deviation were found to have a strong relationship with the weld defect density. Based on the observation, a new mechanism of the penetrator formation during HF ERW process is proposed.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.11 no.9
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• pp.439-453
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• 2001

This study deals with the free vibration of two identical circular plates coupled with a bounded fluid. An analytical method based on the finite Fourier-Bessel series expansion and Rayleigh-Ritz method is suggested. In the theory, it is assumed that the ideal fluid in a rigid cylindrical container and the two plates are clamped along the plate edges. The proposed method is verified by the finite element analysis using commercial program with a good accuracy. Two transverse vibration modes, namely in-phase and out-of-phase, are observed alternately in the fluid-coupled system when the number of nodal circles increases for the fixed nodal diameter. The effect of gap between the plates on the fluid-coupled natural frequencies sis also investigated.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.7
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• pp.1677-1684
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• 1996

The theory of optimal stack filtering has been used in difference of estimates(DoE) approach to the detection of intensity edges in noisy image. In this approach, stack filters are applied to a noisy image to obtain local estimates of the dilated and eroded versions of the noise-free image. Thresholding the difference between these two estimates produces the estimated edge map. In this paper, the DoE approach is modified by imposing a symmetry condition of the data used to train the two stack filers. Under this condition, the stack filters obtained are duals of each other. Only one filter must therefore be trained;the other is simply its dual. They also produce statistially unbiased estimates. This new technique is called the symmetric Difference of Estimates (SDoE) approach.

• Structural Engineering and Mechanics
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• v.33 no.6
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• pp.657-674
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• 2009

In this paper a 3-D continuum damage mechanics formulation for composite laminates and its implementation into a finite element model that is based on the layer-wise laminate plate theory are described. In the damage formulation, each composite ply is treated as a homogeneous orthotropic material exhibiting orthotropic damage in the form of distributed microscopic cracks that are normal to the three principal material directions. The progressive damage of different angle ply composite laminates under quasi-static loading that exhibit the free edge effects are investigated. The effects of various numerical modeling parameters on the progressive damage response are investigated. It will be shown that the dominant damage mechanism in the lay-ups of [+30/-30]s and [+45/-45]s is matrix cracking. However, the lay-up of [+15/-15] may be delaminated in the vicinity of the edges and at $+{\theta}/-{\theta}$ layers interfaces.

• Journal of the Korea institute for structural maintenance and inspection
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• v.2 no.4
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• pp.217-223
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• 1998

본 논문에서는 원형연단이 단순지지 되어 있을 때 단순과 자유의 방사연단 조건을 갖는 부채꼴형 평판의 휨진동에 대한 엄밀한 해석방법을 제시한다. Ritz방법을 이용하여 수직진동변위를 두가지 적합 함수식으로 가정하였다. 이러한 두가지의 적합 함수식은 (1) 수학적으로 완전한 대수삼각다항함수와, (2) 둔각 모서리에서의 휨모멘트 특이도를 고려하는 모서리함수로 구성되어있다. 본 연구에서는 방사연단의 둔각 모서리를 이루는 부채꼴형 각도의 범위에 따른 엄밀한 진동수 및 수직진동 변위의 전형적인 등고선을 제시하였다.

• Journal of Power System Engineering
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• v.9 no.3
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• pp.58-65
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• 2005

This paper deals with the free vibrations of truncated conical shell with uniform thickness by the transfer influence coefficient method. The classical thin shell theory based upon the $Fl\ddot{u}gge$ theory is assumed and the governing equations of a conical shell are written as a coupled set of first order differential equations using the transfer matrix. The Runge-Kutta-Gill integration and bisection method are used to solve the governing differential equations and to compute the eigenvalues respectively. The natural frequencies and corresponding mode shapes are calculated numerically for the truncated conical shell with any combination of boundary conditions at the edges. And all boundary conditions and the intermediate supports between conical shell and foundation could be treated only by adequately varying the values of the spring constants. Numerical results are compared with existing exact and numerical solutions of other methods.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2001.11b
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• pp.603-608
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• 2001

This paper deals with the free vibration of two identical circular plates coupled with a bounded fluid. An analytical method based on the finite Fourier-Bessel series expansion and Rayleigh-Ritz method is suggested. In the theory, it is assumed that the ideal fluid is filled between the two plates and the plates are simply supported along the plate edges. The proposed method is verified by the finite element analysis using commercial software with an excellent accuracy. The effect of the plate boundary conditions on the fluid-coupled natural frequency is investigated.

• Advances in nano research
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• v.5 no.2
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• pp.113-126
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• 2017

This paper proposes a new nonlocal higher-order hyperbolic shear deformation beam theory (HSBT) for the static bending and vibration of nanoscale-beams. Eringen's nonlocal elasticity theory is incorporated, in order to capture small size effects. In the present model, the transverse shear stresses account for a hyperbolic distribution and satisfy the free-traction boundary conditions on the upper and bottom surfaces of the nanobeams without using shear correction factor. Employing Hamilton's principle, the nonlocal equations of motion are derived. The governing equations are solved analytically for the edges of the beam are simply supported, and the obtained results are compared, as possible, with the available solutions found in the literature. Furthermore, the influences of nonlocal coefficient, slenderness ratio on the static bending and dynamic responses of the nanobeam are examined.

• Steel and Composite Structures
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• v.35 no.1
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• pp.111-127
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• 2020

The goal of this study is to fill this apparent gap in the area about investigating the effect of porosity distributions on vibrational behavior of FG sectorial plates resting on a two-parameter elastic foundation. The response of the elastic medium is formulated by the Winkler/Pasternak model. The internal pores and graphene platelets (GPLs) are distributed in the matrix either uniformly or non-uniformly according to three different patterns. The model is proposed with material parameters varying in the thickness of plate to achieve graded distributions in both porosity and nanofillers. The elastic modulus of the nanocomposite is obtained by using Halpin-Tsai micromechanics model. The annular sector plate is assumed to be simply supported in the radial edges while any arbitrary boundary conditions are applied to the other two circular edges including simply supported, clamped and free. The 2-D differential quadrature method as an efficient and accurate numerical approach is used to discretize the governing equations and to implement the boundary conditions. The convergence of the method is demonstrated and to validate the results, comparisons are made between the present results and those reported by well-known references for special cases treated before, have confirmed accuracy and efficiency of the present approach. It is observed that the maximum vibration frequency obtained in the case of symmetric porosity and GPL distribution, while the minimum vibration frequency is obtained using uniform porosity distribution. Results show that for better understanding of mechanical behavior of nanocomposite plates, it is crucial to consider porosities inside the material structure.