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Reconstruction of Tibial Defects in Lower Extremity With Various Versions of Vascularized Fibula Transfer (다양한 형태의 생 비골 이식술을 이용한 경골의 재건)

  • Nam, Sang-Hyun;Kim, Bom-Jin;Koh, Sung-Hoon;Chung, Yoon-Kyu
    • Archives of Reconstructive Microsurgery
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    • v.15 no.1
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    • pp.17-25
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    • 2006
  • Twelve cases in eleven patients with segmental bone defects were treated with contralateral fibula free flap and ipsilateral island fibula flap in an antegrade, retrograde or bidirectional flow fashion. Five cases were managed with free flaps and seven were with ipsilateral fibula island transfer. Among seven cases, antegrade fashion was three, retrograde was three, and bidirectional was one. All patients were related with open tibial fractures and its sequelae except one who had open foot bone fracture. According to Gustilo's classification, ten patients were type IIIb and one was type IIIc. Basically, antegrade-flow flaps based on the peroneal vessels as in the conventional free flap were used for the proximal or middle one-third tibial defects. On the contrary, retrograde-flow flaps based on the communicating branch between the peroneal and posterior tibial vessels were used for the middle or distal one-third of the tibia. Bidirection-flow flap based on intact peroneal vessels were used for the middle portion of the tibia. The patients who have undergone ipsilateral fibula island flap had one of the following problems: a previously failed free flap, below-knee amputation of the opposite leg because of open tibial fracture, refusal to use the contralateral sound leg, or poor general condition to stand a lengthy operation. Six of the patients who have got ipsilateral fibula island flap also had an associated fibula fracture on the same leg, which was ultimately used as one of the osteotomy sites. The follow-up period was from 1 to 10 years. Two cases of free flap were failed: one patient had below-knee amputation and the other patient had ipsilateral fibula transfer. Other cases were successful and excellent hypertophy of the transferred fibula was achieved. Time to bone union ranged from 4 to 11 months. Time to full weight bearing was from 5 to 13 months after surgery. All of the transferred fibulas showed hypertrophy after weight bearing. In one case, stress fracture was developed during ambulation, which was healed conservatively. Nonunion occurred in two cases, which were treated with a long leg cast and cancellous bone graft, respectively. Length discrepancy of the legs was noted. The limb was shorter by an average 0.5 cm in three cases, longer by 1.1 cm in one case. In the case of island fibula transfer, limited arc of rotation was not a problem. Other disabling complications were not seen. We believe that these diverse modalities using a vascularized fibula will make us more comfortable to handle major bone defects.

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Thermodynamics of Hydrogen-Induced Phase Separation on Pd-Co Alloys (수소유기에 따른 Pd-Co합금들의 상 분리 현상에 대한 열역학적 고찰)

  • Song, D.M.;Park, C.N.;Choi, J.
    • Transactions of the Korean hydrogen and new energy society
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    • v.16 no.3
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    • pp.244-252
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    • 2005
  • It is very interesting and important in the academic point of view and in practical use the hydrogen-induced phase separation(HIPS) which appears during hydrogen heat treatment. Since hydrogen can be removed very fast by pumping it out the hydrogen-induced new lattice phase which can not be obtained without hydrogen can be preserved as meta-stable state. In this study it has been investigated whether the HIPS appear in Pd-Al, Pd-Co, Pd-Cr, Pd-Ti, Pd-V and Pd-Zr alloys and discussed thermodynamic representation of the HIPS. The Pd alloys were arc-melted under argon atmosphere and remelted 4 or 5 times for homogenization. The alloys were annealed at 600$^{\circ}C$ under vacuum for 24 hrs and then subjected to pressure-composition isotherm measurements at 100$^{\circ}C$. The hydrogen heat treatment(HHT) of samples was carried out at 600$^{\circ}C$ under hydrogen pressure of 70 bar for 6 days and PC isotherms at 100$^{\circ}C$ were measured. By comparing the PC isotherms measured before and after HHT, occurrence of phase separation was determined. The experimental results showed that the HIPS appeared only in Pd-0.05Co alloy. For Pd-Co alloys with various composition the PC isotherms were measured. By adopting Park-Flanagan model for ternary thermodynamics the Gibbs free energy change for Pd-Co-H solid solution was calculated and subsequently with this the HIPS in Pd-Co alloy was explained fairly.

The Effect of Ghrelin on $Ca^{2+}$ Concentration in Thyroid FRTL-5 Cells

  • Kim, Byung-Joo;Park, Young-Joo;Park, Do-Joon;So, In-Suk;Kim, Ki-Whan
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.4
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    • pp.195-200
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    • 2004
  • Ghrelin is a newly discovered peptide, which is released from the stomach and neurons in the hypothalamic arcuate nucleus (ARC), and potently stimulates growth hormone release and food intake. In the present study, we investigated the effect of ghrelin on $[Ca^{2+}]_i$ in thyroid FRTL-5 cells. Ghrelin (5 nM) increased $[Ca^{2+}]_i$ and TSH (1 unit/l) had an additive effect on $[Ca^{2+}]_i$ when extracellular normal solution was 1.1mM $Ca^{2+}$ containing Coon's modified Ham's F12 medium. When $Ca^{2+}-free$ medium containing 2 mM EGTA replaced the above normal solution, ghrelin also induced a similar rise in $[Ca^{2+}]_i$. In the middle of $[Ca^{2+}]_i$ increment by ghrelin, nifedipine $(1\;{\mu}M)$, nickel $(100\;{\mu}M)$ and $La^{3+}\;(100\;{\mu}M)$ had no effect on $[Ca^{2+}]_i$. After endoplasmic reticulum was depleted by cyclopiazonic acid $(CPA;10\;{\mu}M)$, ghrelin caused no visible change on $[Ca^{2+}]_i$ in $Ca^{2+}-free$/2 mM EGTA solution. These results suggest that ghrelin can increase $[Ca^{2+}]_i$ through endoplasmic reticulum in thyroid FRTL-5 cells.

An Analysis of the Reinforced Concrete Circular Ring Sector Plates with Arbitrary Boundary Conditions (任意의 境界條件을 갖는 鐵筋콘크리트 扇形板의 解析(II) - 第 2報 鐵筋比 및 邊長比의 影響 -)

  • Jo, Jin-Gu
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.34 no.1
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    • pp.78-86
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    • 1992
  • This paper aims at investigating the effect of steel ratio and the magnitude of edge-ratio on the mechanical characteristics of reinforced concrete ring sector plate. The influence of steel bars was taken into account by coupling stiffness matrix of the steel bar element with that of the concrete plate element without dealing with separate element of steel bar and by establishing the composite stiffness matrix, which leads to the desirable result which does not increase th number of element could be obtained. Through case studies with 6 cases various steel ratios in ring sector plate supported at four edges and 4 cases with different open angles, the influence of the steel ratio was examined. A numerical analysis to find out the effect of the steel ratio d ue to above mentioned cases was carried out by 4 boundary conditions ; all edges clamped (B.C-1), all edges simply supported (B.C-2), curvilinear two edges clamped and other edges free (B.C-3) and curvilinear two edges simply supported and other edges free(B.C-4). The main results obtained are summarized as follows : 1. The effect of steel ratio on the magnitude of lateral deflection and x-directional bending moment at the center of sector plate and the midpoint of outer and inner curvilinear edges is almost the same up to $30^{\circ}$ of open angle. Beyond $30^{\circ}$ of the angle, the larger the angle, the greater the effect of ratio. 2. In design works using balanced steel ratio, the effect of steel bar can be ignored. But for larger open angles, especially greater than $90^{\circ}$, it proves desirable to consider the effect of steel bar. 3. The effect of the arc length of center circle/straight edge on lateral deflection and bending moment is remarkable in B.C-2. For larger open angle, the effect is also noted except for B.C-3 which turn out hardly affected. 4. The effect of the radius of curvature/straight side length on lateral deflection and x-directional bending moment is noted in B.C-2. As open angle increases, B.C-1 and B.C-3 almost agree and B.C-2 approaches B.C-4.

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Surface-Tension Effects on the Flow Caused by a Two-Dimensional Pulsating Source Moving with a Constant Speed beneath the Free Surface (전진하며 동요하는 2차원 특이점에 의하여 발생되는 자유표면파에 미치는 표면장력의 영향)

  • Hang-S.,Choi;Jae-S.,Choi
    • Bulletin of the Society of Naval Architects of Korea
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    • v.27 no.1
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    • pp.57-62
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    • 1990
  • This paper deals with the flow caused by a two-dimensional pulsating source, which moves with a constant horizontal speed beneath the free surface. The analysis is based on lincar potential theory including surface tension effects. In the case of subcritical reduced frequencies $\tau<1/4(\tau=U_{\omega}/g$, U=constant speed, $\omega$=circular frequency, g=gravitational acceleration), six wave components arc found. Two of them are largely affected by surface tension, which propagate ahead of the source in the direction of and opposite to the steady translation, respectively. The rest are almost identical with those found by Haskind(1954), i.e. for which the surface tension effect is negligible. For low oscillation frequencies, the resonant frequency still exists at $\tau$ only slightly greater than 1/4. For oscillation frequencies greater than $\nu(={\omega}^2/g)>20$, the surface tension effect is so significant that it disperses generated waves and consequently the singular phenomenon is removed. However, in addition to the gravity breaking, capillary breakings occur when the translation speed coincides with the minimum capillary celerity.

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A CLINICAL STUDY ON SUPERIORLY BASED PLATYSMA MYOCUTANEOUS CERVICAL FLAP FOR RECONSTRUCTION FOLLOWING INTRAORAL SOFT TISSUE CANCER SURGERY (구강내 연조직 암 절제후 상부기조 광경근 근피부 경부 피판을 이용한 구강내 재건에 관한 임상적 연구)

  • Park, Bong-Wook;Byun, June-Ho;Shin, Hee-Suk;Kim, Jong-Ryoul
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.30 no.1
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    • pp.83-91
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    • 2008
  • The goal of reconstruction following ablative therapy for intraoral cancer is the restoration of form and function to permit a return to activities of daily life. Traditional reconstruction includes split thickness skin grafts, myocutaneous flaps and, more recently, various free flaps. Free flaps provide higher level of functional recovery relative to that seen with other techniques but require the complexity of the technique and microvascular anastomosis and thus, extended surgical time and occasionally a second team for harvesting. The platysma myocutaneous cervical flap is a possible alternative for intraoral reconstruction. It is thin and pliable like the tissue provided by the radial forearm free flap. It can be harvested with enough tissue to close most head and neck ablative defects. There is virtually no donor site morbidity involved. This study evaluated 7 patients affected by intraoral squamous cell carcinoma (SCC). All patients underwent the resection of intraoral SCC with neck dissection and subsequent intraoral reconstruction with the superiorly based platysma myocutaneous cervical flap. Flap-related complications occurred in 3 patients. Adjuvant radiation therapy was performed in 3 patients. Average follow-up was 24.1 months after surgery, with a range of 8 to 42 months. All patients presented self assessment of discomfort associated with intraoral recipient sites and cervical donor sites. However, the neck function measured by two-inclinometer technique was within the normal range during relatively long term follow-up period. Our study concluded that superiorly based platysma myocutaneous cervical flap is good alternative to free flaps, especially for relatively smaller defects and for the defects appropriate for the rotation arc of the flap.

Electrochemical Behaviors of Binary Ti-Zr Alloys

  • Oh, M.Y.;Kim, W.G.;Choe, H.C.;Ko, Y.M.
    • Corrosion Science and Technology
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    • v.8 no.2
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    • pp.89-92
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    • 2009
  • Pure Ti as well as Ti-6Al-4V alloy exhibit excellent properties for dental implant applications. However, for a better biocompatibility it seems important to avoid in the composition the presence of V due to the toxic effects of V ion release. Thus Al and V free and composed of non-toxic element such as Nb, Zr alloys as biomaterials have been developed. Especially, Zr contains to same family in periodic table as Ti. The addition of Zr to Ti alloy has an excellent mechanical properties, good corrosion resistance, and biocompatibility. In this study, the electrochemical characteristics of Ti-Zr alloys for biomaterials have been investigated using by electrochemical methods. Methods: Ti-Zr(10, 20, 30 and 40 wt%) alloys were prepared by arc melting and homogenized for 24 hr at $1000^{\circ}C$ in argon atmosphere. Phase constitutions and microstructure of the specimens were characterized by XRD, OM and SEM. The corrosion properties of the specimens were examined through potentiodynamic test (potential range of -1500 ~ 2000 mV), potentiostatic test (const. potential of 300 mV) in artificial saliva solution by potentiostat (EG&G Co, PARSTAT 2273. USA).

Development of Rapid Tooling using Investment Casting & R/P Master Model (R/P 마스터 모델을 활용한 정밀주조 부품 및 쾌속금형 제작 공정기술의 개발)

  • Jeong, Hae-Do;Kim, Hwa-Young
    • Journal of Korea Foundry Society
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    • v.20 no.5
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    • pp.330-335
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    • 2000
  • Functional metal prototypes are often required in numerous industrial applications. These components are typically needed in the early stage of a project to determine form, fit and function. Recent R/P(Rapid Prototyping) part are made of soft materials such as plastics, wax, paper, these master models cannot be employed durable test in real harsh working environment. Parts by direct metal rapid tooling method, such as laser sintering, by now are hard to get net shape, pores of the green parts of powder casting method must be infiltrated to get proper strength as tool, and new type of 3D direct tooling system combining fabrication welding arc and cutting process is reported. But a system which can build directly 3D parts of high performance functional material as metal park would get long period of system development, massive investment and other serious obstacles, such as patent. In this paper, through the rapid tooling process as silicon rubber molding using R/P master model, and fabricate wax pattern in that silicon rubber mold using vacuum casting method, then we translated the wax patterns to numerous metal tool prototypes by new investment casting process combined conventional investment casting with rapid prototyping & rapid tooling process. With this wax-injection-mold-free investment casting, we developed new investment casting process of fabricating numerous functional metal prototypes from one master model, combined 3-D CAD, R/P and conventional investment casting and tried to expect net shape measuring total dimension shrinkage from R/P pare to metal part.

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Sound Characteristics and Hand of Fabrics for Blouse (블라우스용 직물의 소리 특성과 태)

  • 이은주;조길수
    • Journal of the Korean Society of Clothing and Textiles
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    • v.24 no.4
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    • pp.605-615
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    • 2000
  • This study was carried out to investigate sound characteristics including sound parameters and subjective sensation, and primary hand values related with sound of fabrics for blouse, and furthermore to predict subjective sound sensation with mechanical properties and sound parameters. Sound of specimens was analyzed by FFT. Level pressure of total sound(LPT), loudness(Z), coefficients of autoregressive(AR) functions for fitting the spectra, and sound color factors(ΔL and Δf) were obtained as sound parameters. Primary hand values for women's thin dress were calculated by using KES-FB. Subjective sensation for sound including softness, loudness, sharpness, clearness, roughness, highness, and pleasantness was evaluated by free modulus magnitude estimation. The results were as follows; 1. Fabrics for blouse showed similar spectral shapes to one another in that amplitude values were lower in most ranges of frequencies than fabrics for other uses. 2. It was found that fabrics for blouse were less louder because LPT, loudness(Z), and ARC values were lower than other fabrics. 3. Primary hand values indicated that specimens were soft-touched, flexible, and less crisp. Among primary hands related with sound, Shari values were higher for silk fabrics than for synthetic ones, while the values for Kishimi were similar, 4. Fabrics for blouse were rated more highly for softness, clearness, and pleasantness than for loudness, sharpness. roughness, and highness. Silk fabrics were evaluated more pleasant than synthetic fabrics. 5. Subjective sensation for sound of blouse fabrics were predicted with mechanical properties and physical sound parameters.

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A Shortest Path Planning Algorithm for Mobile Robots Using a Modified Visibility Graph Method

  • Lee, Duk-Young;Koh, Kyung-Chul;Cho, Hyung-Suck
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.1939-1944
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    • 2003
  • This paper presents a global path planning algorithm based on a visibility graph method, and applies additionally various constraints for constructing the reduced visibility graph. The modification algorithm for generating the rounded path is applied to the globally shortest path of the visibility graph using the robot size constraint in order to avoid the obstacle. In order to check the visibility in given 3D map data, 3D CAD data with VRML format is projected to the 2D plane of the mobile robot, and the projected map is converted into an image for easy map analysis. The image processing are applied to this grid map for extracting the obstacles and the free space. Generally, the tree size of visibility graph is proportional to the factorial of the number of the corner points. In order to reduce the tree size and search the shortest path efficiently, the various constraints are proposed. After short paths that crosses the corner points of obstacles lists up, the shortest path among these paths is selected and it is modified to the combination of the line path and the arc path for the mobile robot to avoid the obstacles and follow the rounded path in the environment. The proposed path planning algorithm is applied to the mobile robot LCAR-III.

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