• Title/Summary/Keyword: fragmentation size

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Effect of gamma-irradiation on the Physicochemical Properties of Hemoglobin

  • Lee, Seung-hwan;Song, Kyung-Bin
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2003.10a
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    • pp.135.1-135
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    • 2003
  • To elucidate the effect of gamma-irradiation on the molecular properties of hemoglobin, the secondary, tertiary structure, and the molecular weight size of the protein were examined after irradiation at 0.5, 1, 5, and 10 kGy. Gamma-irradiation of hemoglobin solutions caused the disruption of the ordered structure of the protein molecules, as well as degradation, cross-linking, and aggregation of the polypeptide chains. A SDS-PAGE study indicated that irradiation caused initial fragmentation of the proteins and subsequent aggregation due to cross-linking of the protein molecules. The effect of irradiation on the protein was more significant at lower protein concentrations. Ascorbic acid decreased the degradation and aggregation of proteins by scavenging oxygen radicals that were produced by irradiation. A circular dichroism study showed that irradiation decreased the helical content of hemoglobin with a concurrent increase of the aperiodic structure content. Fluorescence spectroscopy indicated that irradiation decreased the emission intensity that was excited at 280 nm.

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A Development of a Transient Hydrogen Generation Model for Metal-Water Interactions

  • Lee, Jin-Yong;Park, Goon-Cherl;Lee, Byung-Chul
    • Nuclear Engineering and Technology
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    • v.32 no.6
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    • pp.549-558
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    • 2000
  • A transient model for hydrogen generation in molten metal-water interactions was developed with separate models for two stages of coarse mixing and stratification. The model selves the mechanistic equations (heat and mass transfer correlation, heat conduction equation and the concentration diffusion equation) of each stage with non-zero boundary conditions. Using this model, numerical simulations were performed for single droplet experiments in the Argonne National Laboratory tests and for FITS tests that simulated dynamic fragmentation and stratification. The calculation results of hydrogen generation showed better agreement to the experiment data than those of previous works. It was found from the analyses that the steam concentration to be reached at the reaction front might be the main constraint to the extent of the metal droplet oxidized. Also, the hydrogen generation rate in the coarse mixing stage was the higher than that in the stratification stage. The particle size was the most important factor in the coarse mixing stage to predict the amount of hydrogen generation.

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Experimental Study on the Size Distribution of Fragmentation by Effects of Drilling Pattern and Time Delay Using the Sequential Blasting Machine (천공패턴 및 기폭시차의 변화에 의한 파쇄암의 입도 분포 연구)

  • 이춘우;양형식;송승근
    • Explosives and Blasting
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    • v.18 no.4
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    • pp.43-54
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    • 2000
  • 본 연구에서는 계단식 발파에서 파쇄입도에 영향을 미치는 변수들로부터 대괴를 줄이는 새로운 발파패턴을 제시하고자 하였다. 광주 제2순환도로 대절토 구간에서 천공경, 1회발파공수, 화약의 종류 등의 영향을 파쇄암의 평균입자의 크기와 상위 5개의 대괴 평균치로 나타내었다. 그 결과 대괴의 크기는 평균 파쇄암의 크기와 선형적인 추이를 나타내었으며 평균파쇄도는 저폭속 폭약인ANFO가 NewMITE 보다 좋은 결과를 보였다. 또 천공경 65 mm와 75 mm로 ANFO즉 사용했을 때 파쇄도는 약포의 직경이 작은 경우에 파쇄도가 양호하게 나타났고 총공수와 파쇄도를 살펴본 결과 평균파쇄도와 대괴의 크기는 대제적으로 총공수의 증가에 비례하여 커지는 경향이었으며 평균파쇄도 보다는 대괴의 크기가 증가의 폭이 컸다. 한편 첫째 열을 2단 분리장약했을 때가 일반 발파나 1열 소단벤치발파 때보다 파쇄도가 좋았다.

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Landscape Analysis of the Hallasan National Park in a Jeju Island Biosphere Reserve: Fragmentation Pattern (제주 생물권보전지역 내 한라산국립공원의 경관분석 : 단편화 현상)

  • Kang, Hye-Soon;Kim, Hyun-Jung;Chang, Eun-Mi
    • Korean Journal of Environment and Ecology
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    • v.22 no.3
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    • pp.309-319
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    • 2008
  • Roads are an indicator of anthropogenic activity causing ecosystem disturbances and often lead to habitat fragmentation, habitat loss, and habitat isolation. The Hallasan National Park(153.4$km^2$) on Jeju Island being distinguished for its unique geology, topography, and biota has also been designated as a core area of UNESCO Man and the Biosphere(MAB) Reserve. Although the high conservation value of this park has contributed to a rapid growth of tourists and road construction, landscape changes due to roads have not been examined yet. We used GIS systems to examine the fragmentation pattern caused by roads, in relation to its zonation, elevation, and vegetation. When a buffer was applied to roads(112m width for paved roads and 60m width for both legal and illegal trails), the park consisted of 100 fragments. The ten fragments generated after applying buffer to only paved roads and legal trails ranged from $0.002km^2$ to $38.2km^2$ with a mean of $14.2km^2$, and about 7% of both nature conservation zone and nature environment zone of the park were edge. Fragments in both east and west ends of the park and around the summit exhibited relatively high shape indices with means of 5.19(for 100 fragments) and 7.22(for 10 fragments). All five legal trails are connected to the pit crater of the mountain and vegetation changed from broadleaf forests and conifer forests to grasslands with elevation, consequently resulting in dramatic fragment size reduction in grasslands at high elevation, in particular above 1,400m, where endemic and alpine plants are abundant. These results show that in Hallasan National Park the risks of habitat deterioration and habitat loss due to fragmentation may be more severe in the nature conservation zone dominated by Baengnokdam than in the nature environment zone. Therefore, current road networks of the park appear to fall short of the goal of the national park for ecosystem conservation and protection. Considering that the entire Hallasan National Park also serves as a MAB core area, conservation efforts should focus, first of all, on park rezoning and road management to mitigate habitat fragmentation.

Comparison in Porous Structure and Water Eetention with the Different Porous Media by Fractal Fragmentation Model (다공성 매체의 차원 분열 모델 적용에 의한 토양과 상토의 공극분포와 보수력 비교)

  • Oh, Dong-Shig;Kim, Lee-Yul;Jung, Yeong-Sang
    • Korean Journal of Soil Science and Fertilizer
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    • v.40 no.3
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    • pp.189-195
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    • 2007
  • Using fractal dimensionality theory proposed by Riew and Sposito (1991), we attempted to analyze quantitatively the characteristics of porous distribution for built-in soils in the mini-lysimeter and artificial seed-bed media. The 2" stainless core soil samples were taken from lysimeter soils. Artificial seed-bed media were compacted in the acrylic core filled with raw materials consisted of cocopeat, zeolite and perlite. N (Constant number of partitioned group size smaller media volumes) and r (Self-similarity ratio) parameters consisting of fractal dimension D=log(N)/log(1/r) were obtained by Excel Programme using the Riew and Sposito's fractal model. The pore distribution of tested media was screened in pore size and its occurring frequency. The results reveal that the distribution range of pores is wider in the lysimeter soils than in the seed-bed media, while average size of pores in the media is smaller in lysimeter core soils than in seed-bed media.

Sustained Release Injectable of Recombinant Bovine Somatotropin in Biodegradable Poly(D,L-lactide-co-glyceride) Microspheres (생분해성 폴리락티드/글리콜리드 미립구를 이용한 재조합 소 성장호르몬(rBST)의 지속성주사제 설계)

  • Jeon, Hong-Ryeol;Lee, Bong-Sang;Kown, Do-W;Yoon, Mi-Kyoung;Jeon, Hyun-Joo;Shin, Taek-Hwan;Choi, Young-Wook
    • Journal of Pharmaceutical Investigation
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    • v.32 no.3
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    • pp.199-207
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    • 2002
  • In order to develop a sustained release formulation of bovine somatotropin (BST), which has been used to increase the body weight of oxen or the milk production of dairy cows, poly(D,L-lactide-co-glyceride)(PLGA) microspheres were made by W/O/W multiple emulsification method and solvent extraction method. Physical properties including particle size, drug entrapment, drug release, protein denaturation, and in vivo body weight increase in rats were characterized. The size of the microspheres was increased as the molecular weight of PLGA increased. When Span 65 and stearic acid during preparation were added, the size was decreased but the amount of surface protein was increased, resulting in a high loading efficiency, with fast release of BST from the microspheres. Aggregation or fragmentation of BST by SDS-PAGE during microsphere preparation and drug release study was not observed. Body weight of Sprague-Dawley's male rats was significantly increased after subcutaneous administrations of BST-loaded PLGA microspheres. There was a good correlation between in vivo weight gain and in vitro release rate of microspheres. PLGA microspheres with a high surface protein ratio could be a good candidate for the sustained delivery of BST.

Synergistic Effect of Glucoamylase and $\alpha$-Amylase in Enzymatic Hydrolysis of Raw Corn Starch in an Agitated Bead Reaction System (분쇄마찰매체 효소반응계에서 생전분 효소당화를 위한 Glucoamylase와 Alpha-Amylase의 보완작용)

  • 이용현;박동찬
    • Microbiology and Biotechnology Letters
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    • v.18 no.4
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    • pp.352-359
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    • 1990
  • The synergistic effect of glucoamylase and a -amylase on the hydrolysis of raw corn starch in an agitated bead reaction system was studied by investigating the changes of sugar profiles, the granular structure, particle size distribution, and X-ray diffraction pattern of residual raw corn starch. The enzymatic hydrolysis of raw corn starch was greatly enhanced by synergistic effect of glucoamylase and $\alpha$ -amylase. Even though the sugar profiles were mainly determined by the mixing ratio of glucoamylase and $\alpha$-amylase; raw starch was mainly converted to glucose directly without accumulation of any significant amount of oligosaccharides. The cavity formation and fragmentation phenomena of raw corn starch granule subjected to enzyme reaction were analyzed by means of SEM and the particle size distribution. The X-ray diffraction pattern of raw starch was not changed at the initial stage of reaction but slightly changed at the late stage of hydrolysis, which may be caused by the preferential degradation of amorphous region by enzymatic reaction, not by the destruction of microcrystalline structure of raw corn starch.

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Design and Performance Evaluation of a Flash Compression Layer for NAND-type Flash Memory Systems (NAND형 플래시메모리를 위한 플래시 압축 계층의 설계 및 성능평가)

  • Yim Keun Soo;Bahn Hyokyung;Koh Kern
    • Journal of KIISE:Computer Systems and Theory
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    • v.32 no.4
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    • pp.177-185
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    • 2005
  • NAND-type flash memory is becoming increasingly popular as a large data storage for mobile computing devices. Since flash memory is an order of magnitude more expensive than magnetic disks, data compression can be effectively used in managing flash memory based storage systems. However, compressed data management in NAND-type flash memory is challenging because it supports only page-based I/Os. For example, when the size of compressed data is smaller than the page size. internal fragmentation occurs and this degrades the effectiveness of compression seriously. In this paper, we present an efficient flash compression layer (FCL) for NAND-type flash memory which stores several small compressed pages into one physical page by using a write buffer Based on prototype implementation and simulation studies, we show that the proposed scheme offers the storage of flash memory more than $140\%$ of its original size and expands the write bandwidth significantly.

Sex-related demographics in two remnant populations of a dioecious tree Ilex cornuta (Aquifoliaceae): implications for conservation

  • Shin, Sookyung;Lee, Hakbong;Lee, Jei-Wan;Kang, Hyesoon
    • Journal of Ecology and Environment
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    • v.43 no.3
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    • pp.320-331
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    • 2019
  • Background: Dioecious plant species having both male and female plants have been investigated regarding sex-related characteristics such as sex ratio, sex-differential resource requirements, and spatial segregation of the sexes. Habitat loss and fragmentation are major threats to the survival of plant populations, but dioecious species are particularly more prone to such habitat degradation than non-dioecious species because of their dimorphic sexual system. We examined the sex-related demographics of two Ilex cornuta populations being different regarding land use history. Methods: During 2016-2017, we examined I. cornuta trees with a basal diameter ${\geq}1.5cm$ in the Yongsu-ri population (YS population) and the Gotjawal Provincial Park population (GP population). Plant sex (male, female, or unsexed) was identified. The tree size (basal diameter and height of the main stem), clonal production (the ramet numbers per genet), and vitality for each clone were measured. The associations between population, sex, tree size, clonal production, and vitality were examined using ANOVAs and contingency table analyses. Finally, point pattern analyses using O-ring statistics were conducted to assess spatial patterns. Results: Upon excluding unsexed trees, the YS population with 74 trees was significantly male-biased (0.66), while the GP population with only 26 trees had a 1:1 sex ratio. In both populations, males and females did not differ in tree size. Although the mean number of ramets differed significantly between populations, females tended to produce more ramets than males. The proportion of weak trees was significantly higher in the YS than in the GP population. Neither population showed evidence of spatial segregation of the sexes. Conclusions: The two populations of dioecious I. cornuta are characterized by the small number of trees and relatively high frequencies of non-reproductive trees. Both indicate that these populations are quite susceptible to environmental and genetic stochasticity. On the other hand, the differences between populations in sex ratio, clonal production, and vitality suggest that conservation efforts for I. cornuta need to be population-specific. In order to help recover and enable this vulnerable species to persist, it is necessary to find ways to enhance their sexual reproduction and simultaneously reduce habitat disturbances due to anthropogenic activities.

Small-scale spatial genetic structure of Asarum sieboldii metapopulation in a valley

  • Jeong, Hyeon Jin;Kim, Jae Geun
    • Journal of Ecology and Environment
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    • v.45 no.3
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    • pp.97-104
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    • 2021
  • Background: Asarum sieboldii Miq., a species of forest understory vegetation, is an herbaceous perennial belonging to the family Aristolochiaceae. The metapopulation of A. sieboldii is distributed sparsely and has a short seed dispersal distance by ants as their seed distributor. It is known that many flowers of A. sieboldii depend on self-fertilization. Because these characteristics can affect negatively in genetic structure, investigating habitat structure and assessment of genetic structure is needed. A total of 27 individuals in a valley were sampled for measuring genetic diversity, genetic distance, and genetic differentiation by RAPDPCR. Results: The habitat areas of A. sieboldii metapopulation were relatively small (3.78~33.60 m2) and population density was very low (five to seven individuals in 20×20 m quadrat). The habitat of A. sieboldii was a very shady (relative light intensity = 0.9%) and mature forest with a high evenness value (J = 0.81~0.99) and a low dominance value (D = 0.19~0.28). The total genetic diversity of A. sieboldii was quite high (h = 0.338, I = 0.506). A total of 33 band loci were observed in five selected primers, and 31 band loci (94%) were polymorphic. However, genetic differentiation along the valley was highly progressed (Gst = 0.548, Nm = 0.412). The average genetic distance between subpopulations was 0.387. The results of AMOVA showed 52.77% of variance occurs among populations, which is evidence of population structuring. Conclusions: It is expected that a small-scale founder effect had occurred, an individual spread far from the original subpopulation formed a new subpopulation. However, geographical distance between individuals would have been far and genetic flow occurred only within each subpopulation because of the low density of population. This made significant genetic distance between the original and new population by distance. Although genetic diversity of A. sieboldii metapopulation is not as low as concerned, the subpopulation of A. sieboldii can disappear by stochastic events due to small subpopulation size and low density of population. To prevent genetic isolation and to enhance the stable population size, conservative efforts such as increasing the size of each subpopulation or the connection between subpopulations are needed.