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Biogenic Synthesis of Metallic Nanoparticles and Their Antibacterial Applications (금속 나노입자의 생체 합성과 항균적 적용)

  • Patil, Maheshkumar Prakash;Kim, Jong-Oh;Seo, Yong Bae;Kang, Min-jae;Kim, Gun-Do
    • Journal of Life Science
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    • v.31 no.9
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    • pp.862-872
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    • 2021
  • Recent studies on synthesis of metallic nanomaterials such as silver (Ag), gold (Au), platinum (Pt), cerium (Ce), zinc (Zn), and copper (Cu) nanoparticles (NPs) using plants and microbes are attracted researchers for their wide range of applications in the field of biomedical sciences. The plant contains abundant of bioactive contents such as flavonoids, alkaloids, saponins, steroids tannins and nutritionals components. Similarly, microbes produce bioactive metabolites, proteins and secretes valuable chemicals such as color pigments, antibiotics, and acids. Recently reported, biogenic synthesis of NPs in non-hazardous way and are promising candidates for biomedical applications such as antibacterial, antifungal, anti-cell proliferative and anti-plasmodia activity. All those activities are dose dependent, along with their shape and size also matters on potential of NPs. Microbes and plants are great source of metabolites, those useful in biomedical field, such metabolites or chemicals involved in synthesis of NPs in an ecofriendly way. NPs synthesized using microbes or plant materials are reveals more non-toxic, facile, and cost-effective compare to chemically synthesized NPs. In present review we are focusing on NPs synthesis using biological agents such as microbes (bacteria, fungi and algae) and plant, characterization using different techniques and their antibacterial applications on pathogenic Gram-positive and Gram-negative organisms.

An Empirical Study on Factors Affecting Organizational Survival of Entertainment Corporations (조직생존요인에 관한 실증분석 : 엔터테인먼트 기업을 대상으로)

  • Kim, Hun;Kim, Jung Hoon
    • Review of Culture and Economy
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    • v.20 no.1
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    • pp.129-161
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    • 2017
  • Korea's entertainment industry laid its foundation in the early 2000s when global popularity of South Korean soap operas increased in Japan. K-pop has been recently leading the popularity in China. However, many Korean entertainment businesses are dying out. This study reviews factors influencing business survival for 42 chosen corporations listed in the Korea Stock Exchange based on organizational ecology. When all of the variables are analyzed at the same time, long period of public offering and high wages and global sales ratio positively affect business survival. When the individual variables are separately analyzed, long period of public offering and CEO incumbency and high wages and global sales ratio positively affect business survival. Meanwhile, size of businesses do not affect the survival. The results of this study imply that policies to help businesses list an entertainment corporation in the Korea Stock Exchange, increase sales and reciprocity with other culture are needed. Laws and institutions for evaluating intangible asset value should be improved. The results also suggest that a corporation should carefully consider change of CEO and make the best use of the popularity of Korean culture to increase global sales and pay competitive wages to attract professionals.

'Gwanghan', A New Forage Winter Oat Cultivar for the Mid-Southern Regions of Korea (중남부지역 적응 내한 다수 조사료용 월동귀리 신품종 '광한')

  • Han, Ouk-Kyu;Park, Tae-Il;Seo, Jae-Hwan;Park, Ki-Hun;Park, Hyong-Ho;Kim, Kyeong-Hoon;Kim, Ki-Jong;Ju, Jung-Il;Jang, Young-Jik;Park, Nam-Geon;Kim, Jung-Gon
    • Korean Journal of Breeding Science
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    • v.42 no.3
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    • pp.226-230
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    • 2010
  • 'Gwanghan' (Avena sativa L.), a winter oat for forage use, was developed by the breeding team at the Department of Rice and Winter Cereal Crop, NICS, RDA in 2009. It was derived from a cross between 'Early80' and 'Gwiri23'. A parent, 'Early80', has early heading and high yielding, while Gwiri23 has mid-heading with large-size grain. Subsequent generations followed by the cross were handled in bulk and pedigree selection programs at Suwon and Yeoncheon, respectively. A line, 'SO96016-B-112-YB-12-7', was selected for earliness, cold tolerance, and good agronomic characteristics and designated as a line name of 'Gwiri64'. The line was subsequently evaluated for cold tolerance, earliness, and forage yield in four different locations, Yesan, Iksan, Kimjae, and Jeju, from 2007 to 2009, and finally named as 'Gwanghan'. Over 3 years, the average forage dry matter yield of 'Gwanghan' harvested at milk-ripe stage was $16.4MT\;ha^{-1}$, compared with $15.4MT\;ha^{-1}$ of check cultivar 'Samhan'. 'Gwanghan's' heading date is about 3 days earlier than that of check cultivar, and is adapted primarily for winter cultivation in the mid-southern regions of Korean peninsula.

Development of Anti-Glare Coating Technique Using Screen Printing (스크린 프린팅 기법을 이용한 눈부심 방지 기술 개발)

  • Choi, Jeongju
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.6
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    • pp.272-277
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    • 2019
  • In this paper, a manufacturing method of an anti-glare cover glass on LCD for outdoor use is proposed. The main specification of cover glass is hardness and anti-glare. Hardness is achieved by using the tempered glass, and anti-glare(AG) film is laminated to meet anti-glare specification no the tempered glass. However, the AG film is difficult to maintain the AG performance continuously because the abrasion resistance of the PET film itself is as weak as about 3H. Therefore, a novel production procedure using screen printing method is proposed. The proposed coating is implemented by applying $ZnO-B_2O_3-SiO_2$ powder on glass surface and the glass is made with enhanced hardness through tempering process. In order to apply the ZBS powder uniformly on the glass surface, a screen printing process is used. The main parameters to be considered in screen printing are the oil concentration and mesh opening size. Because the amount of ZBS powder applied to the printing process is controlled by these two parameters, the correlativity is confirmed through the experiments. In order to evaluate the performance of the proposed method, the haze, surface roughness and transmittance are selected as the performance index and are compared with the AG film. As a result of comparison, it is verified that the transmittance of the proposed tempered glass is 83.1%, which is slightly lower than 89.5% of AG film, but the hardness is more than double to 7H.

The Effects of Functional Capacity and Depression on the Life Satisfaction among the Elderly: Focused on the Mediating Effects of Spirituality (노인의 기능적 능력과 우울이 삶의 만족도에 미치는 영향: 영성의 매개효과를 중심으로)

  • Park, Sunae;Hur, Junsoo
    • 한국노년학
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    • v.37 no.1
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    • pp.125-149
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    • 2017
  • The purpose of this study is to analyse the mediating effects of spirituality on the relationship between functional capacity and depression among the elderly. The conceptual framework was based on the integrated theory by Brief et al.(1993) to life satisfaction. The sample was collected through convenience sampling of 413 elderly persons who were 65 years of age or older drawn from senior welfare centers, community senior centers, and religious institutions in Seoul, Incheon, and Gyeonggi Province. Data analysis was performed using Structural Equation Modeling(SEM). The main findings of the present study are as following: First, spirituality had the mediated effects on which depression and IADL influenced life satisfaction. Particularly, existential spirituality on life satisfaction had larger effect size than religious spirituality. Second, the results showed that religious spirituality had positive effects on existential spirituality. These findings demonstrate that the development and implementation of programs geared for fostering religious spirituality and existential spirituality of senior citizens are needed to improve life satisfaction in the field of social welfare. To this end, the foundation of spiritual practice in the field of social work with older people should be constructed through a spirituality-related system and professional training.

Dredging Material Application Lightweight Foamed Soil Full Scale Test Bed Verification (준설토 활용 경량기포혼합토 실규모 현장 실증 연구)

  • Kim, Dong-Chule;Yea, Gue-Guwen;Kim, Hong-Yeon;Kim, Sun-Bin;Choi, Han-Lim
    • Journal of Coastal Disaster Prevention
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    • v.5 no.4
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    • pp.163-172
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    • 2018
  • To propose the design technique and the execution manual of the LWFS(Lightweight Foamed Soil) method using dredged soil, the operation system for the test-bed integrated management, and to establish an amendment for the domestic quantity per unit and specifications, and a strategy for its internationalization. In order to utilize the dredged soil from the coastal area as a construction material, we constructed the embankment with LWFS on soft ground and monitored its behavior. As a result, it can be expected that the use of LWFS as an embankment material on the soft ground can improve the economic efficiency by reducing the depth and period of soil improvement as well as the uses of nearby dredged soil. To verify the utilization of the dredged soil as a material for light-weighted roadbed, soft ground and foundation ground, and surface processing, perform an experimental construction for practical structures and analyze the behavior. It is expected to be able to improve the soft ground with dredged soil and develop technique codes and manuals of the dredged soil reclamation by constructing a test-bed in the same size of the fields, and establish the criteria and manual of effective dredged soil reclamation for practical use. The application technology of the dredged soil reclamation during harbor constructions and dredged soil reclamation constructions can be reflected during the working design stage. By using the materials immediately that occur from the reclamation during harbor and background land developments, the development time will decrease and an increase of economic feasibility will happen. It is expected to be able to apply the improved soil at dredged soil reclamation, harbor and shore protection construction, dredged soil purification projects etc. Future-work for develop the design criteria and guideline for the technology of field application of dredged soil reclamation is that review the proposed test-bed sites, consult with the institutions relevant with the test-bed, establish the space planning of the test-bed, licensing from the institutions relevant with the test-bed, select a test-bed for the dredged soil disposal area.

An Investigation on Data Needs and Data Reuse Behavior in the Field of Social Sciences (사회과학 분야 연구자의 데이터요구와 데이터 재이용 행위에 관한 연구)

  • Kim, NaYon;Chung, EunKyung
    • Journal of the Korean Society for information Management
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    • v.37 no.4
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    • pp.1-26
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    • 2020
  • In today's increasingly data-intensive academic environment, data is becoming the foundation of academic communication as a research outcome rather than a research by-product. However, there is a limit to guaranteeing actual data reuse only by expanding the data supply or securing accessibility. In order to overcome this, it is necessary to understand the data reuse behavior and data needs in-depth. Therefore, this study attempted to identify the major data reuse behavior and data needs among researchers. To this end, the authors of KCI papers among the data reuse documents of the Korea Social Science Data Archive (KOSSDA) for the past 3 years were targeted. An in-depth interview was conducted with 12 researchers who accepted the interview. As a result, factors considered when reusing data were personal, economic, technical, and social aspects, and it was found that the data itself was used or contextual information of the data was used depending on the purpose of data reuse. The path to acquiring data is a web-based source of information, and a path through informal communication can also be found. In terms of the data needs, it was found that they prefer English, the United States, and institutional producers. Also they have a clear preference for quantitative data from an interviewer-filled interpersonal interview survey method, rich metadata along with raw data, and data that contains identification information. However, due to the lack of confidence in the value, it is negative for the use of data with controlled access and use, and it is difficult to confirm a clear preference because there is no similar data available for selection in terms of size and freshness.

A Study to Improve the Usability of the Smart Sleeping Mask based IoT (사물인터넷 기반 수면안대의 사용감 향상을 위한 연구)

  • Kwak, Jin-Young;Yang, Yeon-Ju;Lim, Jea-Kwan;Yoon, Sang-Cheol;Ahn, Taek-Won
    • Journal of Internet of Things and Convergence
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    • v.8 no.6
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    • pp.27-33
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    • 2022
  • Sleep is an essential factor for living a healthy life, but most modern people complain of poor sleep. For these people, as the need for a means to simply evaluate and manage the quality of sleep increases, devices that can check the sleep state at home without monitoring by an examiner are being developed. The smart sleep mask, which is the subject of this usability test, provides bio-signal monitoring while sleeping so that you can conveniently measure and manage your sleep state for yourself. The purpose of this study is to evaluate the usability and safety of the smart sleep mask, to find and prevent potential factors related to errors in use that may occur, and to develop the comfort and safety of this product. As a result of the formative evaluation of the sleep mask prototype, it was reported that it was difficult to turn on the power and check the results, and that the sleep mask was not comfortable to wear. Different opinions were presented on the size and weight of the sleeping mask by people in different age groups.

Cardioprotective effect of ginsenoside Rb1 via regulating metabolomics profiling and AMP-activated protein kinase-dependent mitophagy

  • Hu, Jingui;Zhang, Ling;Fu, Fei;Lai, Qiong;Zhang, Lu;Liu, Tao;Yu, Boyang;Kou, Junping;Li, Fang
    • Journal of Ginseng Research
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    • v.46 no.2
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    • pp.255-265
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    • 2022
  • Background: Ginsenoside Rb1, a bioactive component isolated from the Panax ginseng, acts as a remedy to prevent myocardial injury. However, it is obscure whether the cardioprotective functions of Rb1 are related to the regulation of endogenous metabolites, and its potential molecular mechanism still needs further clarification, especially from a comprehensive metabolomics profiling perspective. Methods: The mice model of acute myocardial ischemia (AMI) and oxygen glucose deprivation (OGD)-induced cardiomyocytes injury were applied to explore the protective effect and mechanism of Rb1. Meanwhile, the comprehensive metabolomics profiling was conducted by high-performance liquid chromatography and quadrupole time-of-flight mass spectrometry (HPLC-Q/TOF-MS) and a tandem liquid chromatography and mass spectrometry (LC-MS). Results: Rb1 treatment profoundly reduced the infarct size and attenuated myocardial injury. The metabolic network map of 65 differential endogenous metabolites was constructed and provided a new inspiration for the treatment of AMI by Rb1, which was mainly associated with mitophagy. In vivo and in vitro experiments, Rb1 was found to improve mitochondrial morphology, mitochondrial function and promote mitophagy. Interestingly, the mitophagy inhibitor partly attenuated the cardioprotective effect of Rb1. Additionally, Rb1 markedly facilitated the phosphorylation of AMP-activated protein kinase α (AMPKα), and AMPK inhibition partially weakened the role of Rb1 in promoting mitophagy. Conclusions: Ginsenoside Rb1 protects acute myocardial ischemia injury through promoting mitophagy via AMPKα phosphorylation, which might lay the foundation for the further application of Rb1 in cardiovascular diseases.

A Study on the Collection and Analysis of Tire and Road Wear Particles(TRWPs) as Fine Dust Generated on the Roadside (도로변에서 발생되는 미세먼지로써 타이어와 도로 마모입자 채집과 분석 연구)

  • Kang, Tae-Woo;Kim, Hyeok-Jung
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.10 no.3
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    • pp.293-299
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    • 2022
  • Recently, various stakeholder are interested in microplastic to cause pollution of the marine's ecosystem and effort to conduct study of product's life cycle to reduce pollution of marine's ecosystem. The micorplastic refer to materials of the nano- to micro- sized units and it can be classified into primary and secondary. The primary microplastic mean the manufactured for use in the specific field such as the microbead of the cosmetic or cleanser. also, secondary mean the unintentionally generated during use of the product such as the textile crumb by the doing the laundry. Tire and Road Wear Particles(TRWPs) are also defined as secondary microplastic. Typically, TRWPs are created by friction between the tread compound's rubber of the tire and the surface of the road du ring the driving cars. Most of the generated TRWPs exist on the roadside and some of them were carried to marine by the rainwater. In this study, we perform the quantitative analysis of the TRWPs existed in fine dust at the roadside. So, we collected the dust from the roadside in Chungcheongnam-do's C site with a movement of 1,300 cars per the hour. The collected samples were separated according to size and density. And shape analysis was performed using the Scanning Electron Microscope(SEM). We were possible to discover a lot of TRWPs at the fine dust of the 100 ± 20 ㎛. And we analysis it u sing the Thermo Gravimetric Analysis(TGA) and Gas Chromatography/Mass Spectrometer(GC/MS) for the quantitative components from the tire. As a result, it was confirmed that TRWPs generated from the roadside fine dust were included the 0.21 %, and the tire and road components in the generated TRWPs consisted of the 3:7 ratio.