• 제목/요약/키워드: formulation

검색결과 6,666건 처리시간 0.033초

Thermal post-buckling analysis of uniform slender functionally graded material beams

  • Anandrao, K. Sanjay;Gupta, R.K.;Ramchandran, P.;Rao, G. Venkateswara
    • Structural Engineering and Mechanics
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    • 제36권5호
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    • pp.545-560
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    • 2010
  • Two or more distinct materials are combined into a single functionally graded material (FGM) where the microstructural composition and properties change gradually. Thermal post-buckling behavior of uniform slender FGM beams is investigated independently using the classical Rayleigh-Ritz (RR) formulation and the versatile Finite Element Analysis (FEA) formulation developed in this paper. The von-Karman strain-displacement relations are used to account for moderately large deflections of FGM beams. Bending-extension coupling arising due to heterogeneity of material through the thickness is included. Simply supported and clamped beams with axially immovable ends are considered in the present study. Post-buckling load versus deflection curves and buckled mode shapes obtained from both the RR and FEA formulations for different volume fraction exponents show an excellent agreement with the available literature results for simply supported ends. Response of the FGM beam with clamped ends is studied for the first time and the results from both the RR and FEA formulations show a very good agreement. Though the response of the FGM beam could have been studied more accurately by FEA formulation alone, the authors aim to apply the RR formulation is to find an approximate closed form post-buckling solutions for the FGM beams. Further, the use of the RR formulation clearly demonstrates the effect of bending-extension coupling on the post-buckling response of the FGM beams.

Iopamidol과 Ioversol 제제 조영제의 온도변화에 따른 물리화학적 분석 (Physicochemical Analysis according to Temperature Changes of Iopamidol and Ioversol Formulation Contrast Agents)

  • 한범희
    • 대한방사선기술학회지:방사선기술과학
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    • 제43권4호
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    • pp.273-280
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    • 2020
  • In this study, the P contrast agent of Iopamidol, which is a nonionic iodide contrast agent most commonly used as a vascular contrast agent in medical institutions, and the O contrast agent of Ioversol, were studied. The physicochemical changes according to the temperature change were compared and analyzed using the Bruker Avance 500MHz Nuclear Magnetic Resonance Spectrometer owned by the Korea Basic Science Institute (KBSI). There was no physical or chemical change in the O contrast medium of Ioversol formulation in temperature change. However, in the P contrast agent of Iopamidol, a doublet peak began to appear in the 1.1 ppm region of the sample at 60℃, and the doublet peak was clearly observed in the sample at 80℃. As a result of this study, 1H-NMR analysis revealed that the P contrast agent of the Iopamidol formulation was dissociated from chemical bonds as it rose to a high temperature of 60℃ or higher, resulting in the formation of foreign substances. It was evaluated that the O contrast agent of Ioversol formulation had physico-chemical stability than the P contrast agent of Iopamidol formulation. As shown in this study, it is necessary to analyze the physical and chemical changes of contrast agents according to various environmental factors.

A New Formulation System for Slow Releasing of Phosphorous Acid in Soil for Controlling Phytophthora Diseases

  • Park, Hae-Jun;Kim, Sung-Ho;Jee, Hyeong-Jin
    • The Plant Pathology Journal
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    • 제23권1호
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    • pp.26-30
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    • 2007
  • Phosphorous acid is known to effectively control various Oomycetes diseases. The phosphoric acid moves upward and downward through the xylem and phloem in plants. The sustainable forms of the slow releasing chemical in rhizosphere would be ideal to be up-taken by plants. Therefore, we developed a new system for phosphorous acid formulation using a carrier coated with polysaccharides. When the product was applied in rhizosphere, the adequate amount of phosphorous acid was consistently released up to 4 weeks in rhizosphere soils. While soil drenching with phosphorous acid at 1,000 ${\mu}g/ml$ and metalaxyl at 150 ${\mu}g/ml$ were not effective to control pepper Phytophthora blight for 4 weeks, direct application of our formulation product around basal stem of pepper plants resulted in excellent disease control effect against Phytophthora blight over 4 weeks. The application of 4 g of our product per plant was optimum to control the disease, and 8 g product/plant did not cause phytotoxicity. Based on the results, we conclude that the applications of the formulation product once or twice during cropping season can control Phytophthora diseases on various crops.

감마선 조사기술을 이용한 미량원소 비료 나노제제 제조 (Preparation of a Nanosized Micro Element Fertilizer Formulation by using Gamma-irradiation Technique)

  • 박해준;김화정
    • 방사선산업학회지
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    • 제4권4호
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    • pp.347-352
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    • 2010
  • In this study, we addressed a novel nanosized curdlan-silica complex, which is curdlan bound to silica, for the development of a sustain-releasing micro element fertilizer formulation. The complex was obtained as follow steps; First, Curdlan polymer, sodium silicate ($Na_2SiO_3$) and isopropyl alcohol were dissolved in DDW. Next the resultant solution was irradiated by $^{60}Co$ gamma-irradiator (150 TBq of capacity; ACEL, Canada). Then $MgSO_4$ was treated with the resultant solution. The obtained colloidal solution was dried by freeze dryer. Finally, we obtained a novel nanosized curdlan-silica formulation containing $MgSO_4$ from the colloidal solution. The morphology of the complex was characterized by using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The nanosized curdlan-silica complex has a particle size ranging from 20 to 80 nm and high stability. Our results suggested that the nano-complex can be applicable to use in various sustain-releasing formulation for pesticide delivery system (PDS).

The MIN-N family of pure-displacement, triangular, Mindlin plate elements

  • Liu, Y. Jane;Riggs, H.R.
    • Structural Engineering and Mechanics
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    • 제19권3호
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    • pp.297-320
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    • 2005
  • In recent years the pure displacement formulation for plate elements has not been as popular as other formulations. We revisit the pure displacement formulation for shear-deformable plate elements and propose a family of N-node, displacement-compatible, fully-integrated, pure-displacement, triangular, Mindlin plate elements, MIN-N. The development has been motivated by the relative simplicity of the pure displacement formulation and by the success of the existing 3-node plate element, MIN3. The formulation of MIN3 is generalized to obtain the MIN-N family, which possesses complete, fully compatible kinematic fields, in which the interpolation functions for transverse displacement are one degree higher than those for rotations. General element-level formulas for the thin-limit Kirchhoff constraints are developed. The 6-node, 18 degree-of-freedom element MIN6, with cubic displacement and quadratic rotations, is implemented and tested extensively. Numerical results show that MIN6 exhibits good performance for both static and dynamic analyses in the linear, elastic regime. The results illustrate that the fully-integrated MIN6 element has excellent performance in the thin limit, even for coarse meshes, and that it does not require shear relaxation.

Hybrid perfectly-matched-layers for transient simulation of scalar elastic waves

  • Pakravan, Alireza;Kang, Jun Won;Newtson, Craig M.;Kallivokas, Loukas F.
    • Structural Engineering and Mechanics
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    • 제51권4호
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    • pp.685-705
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    • 2014
  • This paper presents a new formulation for forward scalar wave simulations in semi-infinite media. Perfectly-Matched-Layers (PMLs) are used as a wave absorbing boundary layer to surround a finite computational domain truncated from the semi-infinite domain. In this work, a hybrid formulation was developed for the simulation of scalar wave motion in two-dimensional PML-truncated domains. In this formulation, displacements and stresses are considered as unknowns in the PML domain, while only displacements are considered to be unknowns in the interior domain. This formulation reduces computational cost compared to fully-mixed formulations. To obtain governing wave equations in the PML region, complex coordinate stretching transformation was introduced to equilibrium, constitutive, and compatibility equations in the frequency domain. Then, equations were converted back to the time-domain using the inverse Fourier transform. The resulting equations are mixed (contain both displacements and stresses), and are coupled with the displacement-only equation in the regular domain. The Newmark method was used for the time integration of the semi-discrete equations.

Optimizing the Novel Formulation of Liposome-Polycation-DNA Complexes (LPD) by Central Composite Design

  • Sun, Xun;Zhang, Zhirong
    • Archives of Pharmacal Research
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    • 제27권7호
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    • pp.797-805
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    • 2004
  • LPD vectors are non-viral vehicles for gene delivery comprised of polycation-condensed plasmid DNA and liposomes. Here, we described a novel anionic LPD formulation containing protamine-DNA complexes and pH sensitive liposomes composed of DOPE and cholesteryl hemisuccinate (Chems). Central composite design (CCD) was employed to optimize stable LPD formulation with small particle size. A three factor, five-level CCD design was used for the optimization procedure, with the weight ratio of protamine/DNA ($X_1$), the weight ratio of Chems/DNA ($X_2$) and the molar ratio of Chems/DOPE in the anionic liposomes ($X_3$) as the independent variables. LPD size ($Y_1$) and LPD protection efficiency against nuclease ($Y_2$) were response variables. Zeta potential determination was utilized to define the experimental design region. Based on experimental design, responses for the 15 formulations were obtained. Mathematical equations and response surface plots were used to relate the dependent and independent variables. The mathematical model predicted optimized $X_1-X_3$ levels that achieve the desired particle size and the protection efficiency against nuclease. According to these levels, an optimized LPD formulation was prepared, resulting in a particle size of 185.3 nm and protection efficiency of 80.22%.

페로니켈 슬래그 골재를 활용한 비소성 시멘트 모르타르의 강도 특성 (Strength of Non-Sintered Cement Mortar Using Ferro-nickel Slag Aggregate)

  • 윤민식;나형원;형원길
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2022년도 봄 학술논문 발표대회
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    • pp.17-18
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    • 2022
  • Carbon dioxide emissions in the construction sector account for 38% of all industries, and environmental destruction is occurring due to indiscriminate use of natural resources. The purpose of this study is to develop by-product aggregate Non-Sintered Cement(NSC) that can replace sand used as natural aggregate and Portland cement. Therefore, Ground Granulated Blast Furnace Slag, Type C Fly Ash and Type F Fly Ash are used to replace cement, and water granulated ferro-nickel slag(FNS) is used to replace aggregate. The flow, compressive strength and flexural strength of the formulation using sand as an aggregate and the formulation replacing 100% FNS were compared. As a result of the experiment, the formulation using FNS had higher overall strength than the formulation using sand, and as the substitution rate of Type C fly ash increased, the strength was the best. Formulation using FNS is more fluid than using sand. Through this study, we show the possibility of 100% substitution of FNS and its applicability to secondary concrete products of by-product aggregate NSC.

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붕산-붕사-Aluminium sulfate 계 셀룰로오스 단열재의 연소특성 연구 (Combustibility of Cellulose Insulation Treated with Boric acid-Borax-Aluminium sulfate Formulation)

  • 김홍;인세진
    • 한국안전학회지
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    • 제7권4호
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    • pp.7-12
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    • 1992
  • The smouldering combustibility of cellulose insulation treated with boric acid-borax-aluminium sulfate as combustion retardants are examined by cigarette ignition method and electrical cardrige heater method. The effectiveness of Aluminium sulfate as a third combustion are acceptable both smouldering resistance and flame resistance at 18% level of all examined formulation. As the proportion of Aluminium sulfate in the formulation was increased, the flame resistance of cellulose insulation was improved.

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AN UPSTREAM PSEUDOSTRESS-VELOCITY MIXED FORMULATION FOR THE OSEEN EQUATIONS

  • Park, Eun-Jae;Seo, Boyoon
    • 대한수학회보
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    • 제51권1호
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    • pp.267-285
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    • 2014
  • An upstream scheme based on the pseudostress-velocity mixed formulation is studied to solve convection-dominated Oseen equations. Lagrange multipliers are introduced to treat the trace-free constraint and the lowest order Raviart-Thomas finite element space on rectangular mesh is used. Error analysis for several quantities of interest is given. Particularly, first-order convergence in $L^2$ norm for the velocity is proved. Finally, numerical experiments for various cases are presented to show the efficiency of this method.