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Fundamental study on cancer therapy by blocking newborn blood vessels by magnetic force control

  • KIRIMURA, Makoto;AKIYAMA, Yoko;NISHIJIMA, Shigehiro
    • Progress in Superconductivity and Cryogenics
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    • v.20 no.2
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    • pp.11-15
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    • 2018
  • In this study, a cancer treatment by accumulating and aggregating ferromagnetic particles in newborn blood vessels was examined. It is necessary for this treatment to control dispersion-aggregation property of ferromagnetic particles. Ferromagnetic particles required in this method disperse at low magnetic field, aggregate at high magnetic field and maintain the aggregation even after removal of the magnetic field. In order to control the dispersion-aggregation property, the surface of magnetite particles was modified with higher fatty acids having different lengths. As a result, we succeeded to prepare propionic acid-modified magnetite particles that form irreversible aggregation by magnetic field. The model experiments simulating newborn blood vessels showed that these particles can block the flow by the magnetic field, and the blockage was maintained after removal of the magnetic field.

A Study on the Opportunities and Risks in Chinese Construction Market for Foreign Enterprises

  • Luo, Wenyuan;Lee, Yoon-Sun;Kim, Jae-Jun
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2007.11a
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    • pp.732-735
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    • 2007
  • Chinese construction industry has been enjoying a good opportunity for development which appeals to lots of foreign investment. However, the difference in socioeconomic environment and legal environment brings difficulties to foreign enterprises. This paper analyses the institution environment in Chinese construction market. The main objective is to form an insight of Chinese construction environment, and to identify critical factors that may block the way of foreign enterprises.

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Movement authority setting algorithm for Moving Block System (이동 폐색구간 열차시스템에서 이동권한 설정 알고리즘)

  • Kim Seung-yong;Lee Chang-goo;Kim Yong-gyu;Beak Jong-hyun
    • Proceedings of the KIEE Conference
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    • summer
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    • pp.1448-1450
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    • 2004
  • Now a day, the Korean National Railroad is laking new agewith the opening of KTX (Korea Train Express). Korean National Railroad is planning using the GSM-r for put KTX and existing equipment to a good. GSM-R is radio communication method selected by ERTMS (European Rail Traffic Management System). So a new algorithm for train movement is necessary to radio communication form. This paper is come up with an algorithm for like that situation.

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Drug Release Characteristics of Crosslinked Poly(alkylene oxide) Hydrogels (가교된 폴리 알킬렌 옥사이드 하이드로겔의 약물방출 특성)

  • Kim, Shin-Jeong;Lee, Seung-Jin
    • Journal of Pharmaceutical Investigation
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    • v.21 no.2
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    • pp.91-95
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    • 1991
  • Polyethylene glycol, polypropylene glycol and block copolymer of ethylene glycol and propylene glycol were crosslinked by triisocyanate to form water swellable, rubbery polymer. The equilibrium swelling of the hydrogels ranged from 3% to 60% according to the hydrophobic-hydrophilic properties of the prepolymers. Model drugs, sodium salicylate and prednisolone were incorporated in the polymer matrices by swelling loading. Physical properties of the drugs affected the drug release mechanisms due to the change in the swelling behaviors of the polymeric devices. Zero order release was observed in the case of relatively hydrophobic polymer matrices.

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A Study against Attack using Virtualization Weakness (가상화 기술의 취약점을 이용한 공격 대응에 관한 연구)

  • Yang, Hwan Seok
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.8 no.3
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    • pp.57-64
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    • 2012
  • Computing environment combined with development of internet and IT technology is changing to cloud computing environment. In addition, cloud computing is revitalized more because of propagation of LTE and suggestion of N-screen Service. Virtualization is the point technology for suggest IT resource to service form to users in this cloud computing. This technology combines other system physically or divides one system logically and uses resource efficiently. Many users can be provided application and hardware as needed using this. But, lately various attack using weak point of virtualization technology are increasing rapidly. In this study, we analyze type and weak point of virtualization technology, the point of cloud computing. And we study about function and the position which intrusion detection system has to prepare in order to detect and block attack using this.

Hardware Design of 240*320 TFT-LCD Controller (240*320 TFT-LCD의 컨트롤러 하드웨어 설계)

  • Sung, Kwang-Ju;Ha, Chang-Soo;Choi, Byeong-Yoon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2010.05a
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    • pp.167-169
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    • 2010
  • This paper describes hardware design and FPGA verification of TFT-LCD controller used in mobile devices widely. TFT-LCD controller outputs pixel's color information red, green, blue and Hsync, Vsync synchronization signals. We used verilog-hdl to describe TFT-LCD controller and simulated it using modelsim software and verified it's exact operation on Xilinx FPGA. Framebuffer made up Block RAM form in FPGA and TFT-LCD displayed image file.

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A Study of punch and die plate for restriking mold of structure engineering design (리스트라이킹 금형용 펀치와 다이플레이트의 구조 설계에 관한 연구)

  • Kim, Sei-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.8 no.4
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    • pp.708-712
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    • 2007
  • Restriking is a shaping method added to the processed products to get higher precision and accuracy in the press die process. This method is frequently used in bending works and drawing works. The purpose of this research is to develop a design for rectangular drawing die punch and die block form which enables drawing formation and restriking in one set.

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Kullback-Leibler Information of Consecutive Order Statistics

  • Kim, Ilmun;Park, Sangun
    • Communications for Statistical Applications and Methods
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    • v.22 no.5
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    • pp.487-494
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    • 2015
  • A calculation of the Kullback-Leibler information of consecutive order statistics is complicated because it depends on a multi-dimensional integral. Park (2014) discussed a representation of the Kullback-Leibler information of the first r order statistics in terms of the hazard function and simplified the r-fold integral to a single integral. In this paper, we first express the Kullback-Leibler information in terms of the reversed hazard function. Then we establish a generalized result of Park (2014) to an arbitrary consecutive order statistics. We derive a single integral form of the Kullback-Leibler information of an arbitrary block of order statistics; in addition, its relation to the Fisher information of order statistics is discussed with numerical examples provided.

Ultrasound-Aided Monolayer Assembly of Spherical Silica Nanobeads

  • Yun, Sang-Hui;Yun, Seo-Yeong;Lee, Jin-Seok
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.08a
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    • pp.267.1-267.1
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    • 2013
  • In modern science and technology, the organization of building blocks, such as spherical particles and zeolite, is important to form a nanostructure. So, it is essential to develop methods for organizing them into large scale for many precise applications. Up to now, reflux and stirring is widely used method for organization of colloidal particles. However, because this method is hard to organize building block with high coverage and uniform orientation, it is necessary to research another method. In this work, we synthesized spherical silica particles using St$\"{o}$ber method and organized them on the glass which is coated with 3-chloropropyltrimethoxysilane (CP-TMS) and polyethyleneimine (PEI) using Sonication method. Although spherical silica particles are difficult to attach on the glass due to their small attachment site, we improved this problem by coating PEI. We introduced two mode of reaction promotion, sonication (SO) and sonication with stacking between the bare glass (SS), and investigated degree of coverage (DOC) and degree of close packing (DCP).

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Synthesis and Characterization of Dodecanucleotides Containing the XhoI Recognition Sequence with a Phosphorothioate Group at the Cleavege Site

  • 문병조;김상국;김남희;권오신
    • Bulletin of the Korean Chemical Society
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    • v.17 no.11
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    • pp.1031-1036
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    • 1996
  • The synthesis and characterization of diastereomeric dodecanucleotides, d[GATCp(S)TCGAGATC], containing recognition sequence of the XhoI restriction endonuclease with a phosphorothioate internucleotidic linkage the cleavage site are described. Rp and Sp form of diastereomerically pure dinucleoside phosphorothioates d[Cp(S)T] were presynthesized and used for the addition to the growing oligonucleotide chain as a block. The stereochemistry of dinucleoside phosphorothioate was assigned by 31P NMR spectroscopy, enzyme digestion, and reverse-phase HPLC. XhoI restriction endonuclease cut only Rp diastereomer d[GATCp(S))TCGAGATC]. The rate of hydrolysis is slower than that of the unmodified dodecamer d[GATCTCGAGATC]. The phosphorothioate nucleotide is using for determination of the stereochemical course of the XhoI catalyzed reaction.