• 약학회지
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• 제54권6호
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• pp.429-440
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• 2010

HS-SPME-GC/MS was studied and optimized for the determination of 17 orgarnophosphorous pesiticides (OPPs: chlorpyrifos, chlorpyrifos-methyl, demeton-s-methyl, diazinon, dimethoate, EPN, fenitrothion, fenthion, malathion, methidathion, monocrotophos, parathion, phenthoate, phosphamidon, sulfotep, terbufos, triazophos) in blood. Optimum SPME parameters were selected: choice of SPME fiber (85 ${\mu}m$ polyacrylate), pH effect (0.5 N HCl), salt effect ($Na_2SO_4$, 0.2 g; 20%), headspace incubation temperature ($80^{\circ}C$), headspace incubation time (1 min), headspace adsorption time (30 min) and GC desorption time (2 min). These parameters were optimized using HS-SPME autosampler coupled with gas chromatography-mass spectrometry (GC-MS). Method validation was carried out in terms of linearity, limit of detection (LOD), limit of quantitation (LOQ) and recovery in blood. The assay was linear over 0.5~5.0 mg/l ($r^2$=0.955~1.000). Limit of detection (LOD) and limit of quantitation (LOQ) in blood were determined 0.03~0.3 mg/l (S/N=3) and 0.1~1.1 mg/l (S/N=10), respectively. Relative recovery with 0.5, 1 and 5 mg/l (in blood) were 90.8%, 98.5% and 94.1%, respectively. This method will be applied to the determination of the orgarnophosphorous pesticides in postmortem blood. The proposed protocol can be an attractive alternative to be used in routine toxicological analysis.

• 대한의생명과학회지
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• 제28권3호
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• pp.157-169
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• 2022

DNA typing is the typical technology in the forensic science and plays a significant role in the personal identification of victims and suspects. Short tandem repeat (STR) is the short tandemly repeated DNA sequence consisting of 2~7 bp DNA units in specific loci. It is disseminated across the human genome and represents polymorphism among individuals. Because polymorphism is a key feature of the application of DNA typing STR analysis, STR analysis becomes the standard technology in forensics. Therefore, the DNA database (DNA-DB) was first introduced with 4 essential STR markers for the application of forensic science; however, the number of STR markers was expanded from 4 to 13 and 13 to 20 later to counteract the continuously increased DNA profile and other needed situations. After applying expanded STR markers to the South Korean DNA-DB system, it positively affected to low copy number analysis that had a high possibility of partial DNA profiles, and especially contributed to the theft cases due to the high portion of touch DNA evidence in the theft case. Furthermore, STR marker expansion not only contributed to the resolution of cold cases but also increased kinship index indicating the potential for improved kinship test accuracy using extended STR markers. Collectively, the expansion of the STR locus was considered to be necessary to keep pace with the continuously increasing DNA profile, and to improve the data integrity of the DNA-DB.

• 한국안전학회지
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• 제27권3호
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• pp.28-35
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• 2012

We investigated the breakdown patterns of silica glass under the various impacts by forensic scientific analysis. The impacts were chosen by thermal and projectiles impact stress. Thermal impacts under the fire were constructed by changing the position of the flame with gas torches. Physical impacts were constructed with the projectiles of slingshots and rifles by changing the size of the projectiles at the surfaces and the initial distance. Also we identified incident angles of the projectiles by analysis of the punching portion at the glass surface. Under the thermal impacts, the breakdown patterns were various by changing the position of the flame. Especially, the configuration of breakdown patterns had radial shape with the position of the flame at the center of the glass sheet. Under the physical impacts by the projectiles, the breakdown patterns had always radial shape.

• 대한약학회:학술대회논문집
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• 대한약학회 2001년도 Proceedings of the Pharmaceutical Society of Korea
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• pp.220.3-221
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• 2001

• 중환자간호학회지
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• 제11권2호
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• pp.34-50
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• 2018

Purpose : This study aimed to clarify attributes, antecedents, and consequences of forensic nursing competency. Method : Rodgers' evolutionary concept analysis was used to analyze twenty nine articles on forensic nursing based on a systematic review of theology, medicine, psychology, and nursing literature. Results : Forensic nursing competency consists of the following seven attributes: awareness of the medico-legal problem, multidisciplinary integrated knowledge, education and training in forensic science, professional career development, evidence based practice in forensic nursing, collaborative forensic nursing with community partner, safety and security effective communication, and supportive relationships. Finally, we could explain the consequences of forensic nursing competency on knowledge construction in nursing, enhancing professional nursing, and establishing a human rights and social justice based approach. The antecedents of forensic nursing competency were forensic science interest, forensic science experience, and nurses' view of person in forensic-works. Conclusion : Based on these results, we recommend the development of a Korean version of a scale to assess forensic nursing competency.

• 한국멀티미디어학회논문지
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• 제24권4호
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• pp.558-568
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• 2021

The digital image to be accepted as legal evidence, it is important to verify the authentication of the digital image. This study proposes a method of authenticating digital images through three steps of comparing the file structure of digital images taken with iPhone, analyzing the encoding information as well as media logs of the iPhone storing the digital images. For the experiment, digital image samples were acquired from nine iPhones through a camera application built into the iPhone. And the characteristics of file structure and media log were compared between digital images generated on the iPhone and digital images edited through a variety of image editing tools. As a result of examining those registered during the digital image creation process, it was confirmed that differences from the original characteristics occurred in file structure and media logs when manipulating digital images on the iPhone, and digital images take with the iPhone. In this way, it shows that it can prove its forensic authentication in iPhone.

• 한국전자거래학회지
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• 제14권3호
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• pp.169-181
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• 2009

중요한 증거 또는 단서가 컴퓨터를 포함된 디지털 정보기기 내에 존재하는 경우가 증가함에 따라 디지털 포렌식 기술은 광범위하게 적용되고 있다. 본 논문에서는 네트워크에 분산되어 있는 다양한 디지털 정보기기 내에 증거나 단서가 존재하는 경우 저장매체의 모니터링을 통한 분석자료 수집 에이전트와 포렌식 분석 시스템을 연계한 포렌식 감사 시스템을 구현하였다. 본 논문에서 구현한 포렌식 감사 시스템은 기존 시스템에서 제공하지 않는 네트워크를 통한 실시간 감시와 증거 자료를 남김으로써 IT 인프라 환경에서의 사고나 범죄를 예방하거나 추적 감시할 수 있다.

• 대한의생명과학회지
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• 제26권4호
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• pp.275-287
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• 2020

Since its introduction in the forensic field, quantitative PCR (qPCR) has played an essential role in DNA analysis. Quality of DNA should be evaluated before short tandem repeat (STR) profiling to obtain reliable results and reduce unnecessary costs. To this end, various human DNA quantification kits have been developed. Among these kits, the PowerQunat® System was designed not only to determine the total amount of human DNA and human male DNA from a forensic evidence item, but also to offer data about degradation of DNA samples. However, a crucial limitation of the PowerQunat® System is its high cost. Therefore, to minimize the cost of DNA quantification, we evaluated kit performance using a reduced volume of reagents (1/2-volume) using DNA samples of varying types and concentrations. Our results demonstrated that the low-volume method has almost comparable performance to the manufacturer's method for human DNA quantification, human male DNA quantification, and DNA degradation index. Furthermore, using a reduced volume of regents, it is possible to run 2 times more reactions per kit. We expect the proposed low-volume method to cut costs in half for laboratories dealing with large numbers of DNA samples.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제5권4호
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• pp.95-102
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• 2016

기밀 정보 유출, 데이터 파괴 등 디지털 기기에 저장된 정보를 위협하는 침해사고가 계속해서 증가하고 있다. 이와 함께 디지털 침해 사고를 조사하기 위하여 디지털 포렌식 기술 또한 계속해서 발전해 왔다. 디지털 포렌식 기술의 발전으로 인하여 사용자의 행위를 추적할 수 있는 다양한 포렌식 아티팩트들이 발견되었으며, 포렌식 아티팩트로부터 정보를 추출하기 위한 다양한 포렌식 도구가 개발되었다. 하지만 포렌식 도구에서 출력하는 정보는 각기 다른 양식을 갖고 있다. 따라서 포렌식 도구에서 출력하는 정보를 다시 가공해야 하는 작업이 필요하다. 가공된 데이터는 데이터 간의 정보를 비교 분석하여 연관관계를 도출하고 그 의미를 파악해야 한다. 이를 위하여 데이터를 가공하는 작업에서 데이터의 저장과 출력을 효과적으로 하기 위한 방안이 필요하다. 본 논문에서는 침해사고 조사 분석시 필요한 다양한 포렌식 아티팩트 정보를 효과적으로 기술할 수 있는 디지털 포렌식 침해지표 작성 포맷 DFIOC(Digital Forensic Indicators Of Compromise)를 제안한다. DFIOC는 XML 기반의 포맷이며 침해사고 조사에 필요한 다양한 포렌식 아티팩트 정보를 Evidence로 표현하여 기술할 수 있다. 또한 포렌식 분석 결과를 기록하는 Forensic Analysis를 제공하고 있으며, 침해 흔적을 기록하기 위하여 Indicator 항목을 제공하고 있다. 포렌식 분석 과정에 필요한 데이터를 DFIOC 포맷의 문서 하나로 기록할 수 있게 됨으로써 불필요한 데이터 가공이 발생하지 않게 된다. 또한 정규화된 포맷을 통해 수집된 정보를 기록하기 때문에 입출력이 쉬워지며 수집된 정보를 확인하고 상호 연관관계 분석에 활용하기 쉬워진다.

• 대한의생명과학회지
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• 제27권2호
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• pp.105-110
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• 2021

Short Tandem Repeats (STR) analysis which characterized by genetic polymorphism has been widely used in the forensic genetic fields. Unfortunately, mutation occurred in various STR loci could make it difficult to interpret STR data. Thus, the mutation rate of STR loci plays an important role for the data interpretation in human identification and paternity test. To verify the mutation of the STR loci in the Korean population, 545 trio sets (father, mother, and child) were analyzed with two commercial STR kits that include the 23 autosomal STR loci (D1S1656, TPOX, D2S441, D2S1338, D3S1358, FGA, D5S818, CSF1PO, D7S820, D8S1179, D10S1248, TH01, D12S391, VWA D13S317, D16S539, D18S51, D19S433, D21S11, D22S1045, SE33, Penta E and Penta D). As a result, 36 mutations were observed in 14 STR loci. The types of mutation were also classified by the increase or decrease of the alleles. The overall mutation rate was 1.4×10^-3, and the paternal mutation rate was four times higher than that of the maternal. This study will provide more detailed criterion for human identification by the mutation rate of STR loci in the Korean population.