• YAKHAK HOEJI
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• v.54 no.6
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• pp.429-440
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• 2010

HS-SPME-GC/MS was studied and optimized for the determination of 17 orgarnophosphorous pesiticides (OPPs: chlorpyrifos, chlorpyrifos-methyl, demeton-s-methyl, diazinon, dimethoate, EPN, fenitrothion, fenthion, malathion, methidathion, monocrotophos, parathion, phenthoate, phosphamidon, sulfotep, terbufos, triazophos) in blood. Optimum SPME parameters were selected: choice of SPME fiber (85 ${\mu}m$ polyacrylate), pH effect (0.5 N HCl), salt effect ($Na_2SO_4$, 0.2 g; 20%), headspace incubation temperature ($80^{\circ}C$), headspace incubation time (1 min), headspace adsorption time (30 min) and GC desorption time (2 min). These parameters were optimized using HS-SPME autosampler coupled with gas chromatography-mass spectrometry (GC-MS). Method validation was carried out in terms of linearity, limit of detection (LOD), limit of quantitation (LOQ) and recovery in blood. The assay was linear over 0.5~5.0 mg/l ($r^2$=0.955~1.000). Limit of detection (LOD) and limit of quantitation (LOQ) in blood were determined 0.03~0.3 mg/l (S/N=3) and 0.1~1.1 mg/l (S/N=10), respectively. Relative recovery with 0.5, 1 and 5 mg/l (in blood) were 90.8%, 98.5% and 94.1%, respectively. This method will be applied to the determination of the orgarnophosphorous pesticides in postmortem blood. The proposed protocol can be an attractive alternative to be used in routine toxicological analysis.

• Biomedical Science Letters
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• v.28 no.3
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• pp.157-169
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• 2022

DNA typing is the typical technology in the forensic science and plays a significant role in the personal identification of victims and suspects. Short tandem repeat (STR) is the short tandemly repeated DNA sequence consisting of 2~7 bp DNA units in specific loci. It is disseminated across the human genome and represents polymorphism among individuals. Because polymorphism is a key feature of the application of DNA typing STR analysis, STR analysis becomes the standard technology in forensics. Therefore, the DNA database (DNA-DB) was first introduced with 4 essential STR markers for the application of forensic science; however, the number of STR markers was expanded from 4 to 13 and 13 to 20 later to counteract the continuously increased DNA profile and other needed situations. After applying expanded STR markers to the South Korean DNA-DB system, it positively affected to low copy number analysis that had a high possibility of partial DNA profiles, and especially contributed to the theft cases due to the high portion of touch DNA evidence in the theft case. Furthermore, STR marker expansion not only contributed to the resolution of cold cases but also increased kinship index indicating the potential for improved kinship test accuracy using extended STR markers. Collectively, the expansion of the STR locus was considered to be necessary to keep pace with the continuously increasing DNA profile, and to improve the data integrity of the DNA-DB.

• Journal of the Korean Society of Safety
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• v.27 no.3
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• pp.28-35
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• 2012

We investigated the breakdown patterns of silica glass under the various impacts by forensic scientific analysis. The impacts were chosen by thermal and projectiles impact stress. Thermal impacts under the fire were constructed by changing the position of the flame with gas torches. Physical impacts were constructed with the projectiles of slingshots and rifles by changing the size of the projectiles at the surfaces and the initial distance. Also we identified incident angles of the projectiles by analysis of the punching portion at the glass surface. Under the thermal impacts, the breakdown patterns were various by changing the position of the flame. Especially, the configuration of breakdown patterns had radial shape with the position of the flame at the center of the glass sheet. Under the physical impacts by the projectiles, the breakdown patterns had always radial shape.

• Proceedings of the PSK Conference
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• 2001.04a
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• pp.220.3-221
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• 2001

• Journal of Korean Critical Care Nursing
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• v.11 no.2
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• pp.34-50
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• 2018

Purpose : This study aimed to clarify attributes, antecedents, and consequences of forensic nursing competency. Method : Rodgers' evolutionary concept analysis was used to analyze twenty nine articles on forensic nursing based on a systematic review of theology, medicine, psychology, and nursing literature. Results : Forensic nursing competency consists of the following seven attributes: awareness of the medico-legal problem, multidisciplinary integrated knowledge, education and training in forensic science, professional career development, evidence based practice in forensic nursing, collaborative forensic nursing with community partner, safety and security effective communication, and supportive relationships. Finally, we could explain the consequences of forensic nursing competency on knowledge construction in nursing, enhancing professional nursing, and establishing a human rights and social justice based approach. The antecedents of forensic nursing competency were forensic science interest, forensic science experience, and nurses' view of person in forensic-works. Conclusion : Based on these results, we recommend the development of a Korean version of a scale to assess forensic nursing competency.

• Journal of Korea Multimedia Society
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• v.24 no.4
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• pp.558-568
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• 2021

The digital image to be accepted as legal evidence, it is important to verify the authentication of the digital image. This study proposes a method of authenticating digital images through three steps of comparing the file structure of digital images taken with iPhone, analyzing the encoding information as well as media logs of the iPhone storing the digital images. For the experiment, digital image samples were acquired from nine iPhones through a camera application built into the iPhone. And the characteristics of file structure and media log were compared between digital images generated on the iPhone and digital images edited through a variety of image editing tools. As a result of examining those registered during the digital image creation process, it was confirmed that differences from the original characteristics occurred in file structure and media logs when manipulating digital images on the iPhone, and digital images take with the iPhone. In this way, it shows that it can prove its forensic authentication in iPhone.

• The Journal of Society for e-Business Studies
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• v.14 no.3
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• pp.169-181
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• 2009

As the situations that important evidences or clues are found in digital information devices increase, digital forensic technology is widely applied. In this paper, forensic based audit system is implemented by associating forensic analysis system with agent system which monitors and collects data for analysis in storage devices over distributed network nodes. Forensic audit system implemented in this paper can prevent, audit and trace the computer related crimes in IT infrastructure by real time monitoring and evidence seizure.

• Biomedical Science Letters
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• v.26 no.4
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• pp.275-287
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• 2020

Since its introduction in the forensic field, quantitative PCR (qPCR) has played an essential role in DNA analysis. Quality of DNA should be evaluated before short tandem repeat (STR) profiling to obtain reliable results and reduce unnecessary costs. To this end, various human DNA quantification kits have been developed. Among these kits, the PowerQunat® System was designed not only to determine the total amount of human DNA and human male DNA from a forensic evidence item, but also to offer data about degradation of DNA samples. However, a crucial limitation of the PowerQunat® System is its high cost. Therefore, to minimize the cost of DNA quantification, we evaluated kit performance using a reduced volume of reagents (1/2-volume) using DNA samples of varying types and concentrations. Our results demonstrated that the low-volume method has almost comparable performance to the manufacturer's method for human DNA quantification, human male DNA quantification, and DNA degradation index. Furthermore, using a reduced volume of regents, it is possible to run 2 times more reactions per kit. We expect the proposed low-volume method to cut costs in half for laboratories dealing with large numbers of DNA samples.

• KIPS Transactions on Computer and Communication Systems
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• v.5 no.4
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• pp.95-102
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• 2016

Computer security incident such as confidential information leak and data destruction are constantly growing and it becomes threat to information in digital devices. To respond against the incident, digital forensic techniques are also developing to help digital incident investigation. With the development of digital forensic technology, a variety of forensic artifact has been developed to trace the behavior of users. Also, a diversity of forensic tool has been developed to extract information from forensic artifact. However, there is a issue that information from forensic tools has its own forms. To solve this problem, it needs to process data when it is output from forensic tools. Then it needs to compare and analyze processed data to identify how data is related each other and interpret the implications. To reach this, it calls for effective method to store and output data in the course of data processing. This paper aims to propose DFIOC (Digital Forensic Indicators Of Compromise) that is capable of transcribing a variety of forensic artifact information effectively during incident analysis and response. DFIOC, which is XML based format, provides "Evidence" to represent various forensic artifacts in the incident investigation. Furthermore, It provides "Forensic Analysis" to report forensic analysis result and also gives "Indicator" to investigate the trace of incidence quickly. By logging data into one sheet in DFIOC format for forensic analysis process, it is capable of avoiding unnecessary data processing. Lastly, since collected information is recorded in a normalized format, data input and output becomes much easier as well as it will be convenient to use for identification of collected information and analysis of data relationship.

• Biomedical Science Letters
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• v.27 no.2
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• pp.105-110
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• 2021

Short Tandem Repeats (STR) analysis which characterized by genetic polymorphism has been widely used in the forensic genetic fields. Unfortunately, mutation occurred in various STR loci could make it difficult to interpret STR data. Thus, the mutation rate of STR loci plays an important role for the data interpretation in human identification and paternity test. To verify the mutation of the STR loci in the Korean population, 545 trio sets (father, mother, and child) were analyzed with two commercial STR kits that include the 23 autosomal STR loci (D1S1656, TPOX, D2S441, D2S1338, D3S1358, FGA, D5S818, CSF1PO, D7S820, D8S1179, D10S1248, TH01, D12S391, VWA D13S317, D16S539, D18S51, D19S433, D21S11, D22S1045, SE33, Penta E and Penta D). As a result, 36 mutations were observed in 14 STR loci. The types of mutation were also classified by the increase or decrease of the alleles. The overall mutation rate was 1.4×10^-3, and the paternal mutation rate was four times higher than that of the maternal. This study will provide more detailed criterion for human identification by the mutation rate of STR loci in the Korean population.