• Title/Summary/Keyword: foot odor

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Manganese-Enhanced MRI Reveals Brain Circuits Associated with Olfactory Fear Conditioning by Nasal Delivery of Manganese

  • Yang, Ji-ung;Chang, Yongmin;Lee, Taekwan
    • Investigative Magnetic Resonance Imaging
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    • v.26 no.2
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    • pp.96-103
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    • 2022
  • Purpose: The survival of organisms critically depends on avoidance responses to life-threatening stimuli. Information about dangerous situations needs to be remembered to produce defensive behavior. To investigate underlying brain regions to process information of danger, manganese-enhanced MRI (MEMRI) was used in olfactory fear-conditioned rats. Materials and Methods: Fear conditioning was conducted in male Sprague-Dawley rats. The animals received nasal injections of manganese chloride solution to monitor brain activation for olfactory information processing. Twenty-four hours after manganese injection, rats were exposed to electric foot shocks with odor cue for one hour. Control rats were exposed to the same odor cue without foot shocks. Forty-eight hours after the conditioning, rats were anesthetized and their brains were scanned with 9.4T MRI. Acquired images were processed and statistical analyses were performed using AFNI. Results: Manganese injection enhanced brain areas involved in olfactory information pathways in T1 weighted images. Rats that received foot shocks showed higher brain activation in the central nucleus of the amygdala, septum, primary motor cortex, and preoptic area. In contrast, control rats displayed greater signals in the orbital cortex and nucleus accumbens. Conclusion: Nasal delivery of manganese solution enhanced olfactory signal pathways in rats. Odor cue paired with foot shocks activated amygdala, the central brain region in fear, and related brain circuits. Use of MEMRI in fear conditioning provides a reliable monitoring technique of brain activation for fear learning.

Estimation of VOCs Affecting a Used Car Air Conditioning Smell via PLSR (부분최소자승법을 이용한 중고차 에어컨냄새 원인물질 추정)

  • You, Hanmin;Lee, Taehee;Sung, Kiwoo
    • Transactions of the Korean Society of Automotive Engineers
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    • v.21 no.6
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    • pp.175-182
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    • 2013
  • Lately, customers think highly of the emotional satisfaction and as a result, issues on odor are matters of concern. The cases are odor of interior material and air-conditioner of vehicles. In particualar, with respect to the odor of air-conditioner, customers strongly claimed defects with provocative comments : "It smells like something rotten," "It smells like a foot odor," "It stinks like a rag." Generally, it is known that mold of evaporator core in the air-conditioning system decays and this produce VOCs which causes the odor to occur. In this study, partial least squares regression model is applied to predict the strength of the odor and select of important VOCs which affect car air conditioning smell. The PLS method is basically a particular multilinear regression algorithm which can handle correlated inputs and limited data. The number of latent variable is determined by the point which is stabilized mean absolute deviations of VOCs data. Also multiple linear regression is carried out to confirm the validity of PLS method.

Electroencephalography Activities Influenced by Classroom Smells of Male High School (남자고등학교 교실냄새에 대한 뇌파반응)

  • Ryu, Hyun;Ko, WooHyong;Kim, JongWoo;Kim, SooRin;Kim, Min Kyung
    • Science of Emotion and Sensibility
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    • v.16 no.3
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    • pp.387-396
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    • 2013
  • In this study, the influence of classroom smells (foot odor, hair smell, sour smell, and sweat smell) of male high school and sweat smell and the offensive odor substance (ammonia and butyric acid) on the electroencephalography (EEG) activities of 20 female volunteers, ranging in age from 30 to 50 were studied. The representative response of brainwave index by these smells stimuli was most pronounced on temporal lobes among the brain lobes. By comparison with background EEG activities on temporal lobes, the smells reduced the relative alpha band power (0.04~0.13) and increased the relative beta band power (0.02~0.06) and the relative gamma band power (0.03~0.09). The alpha wave was deactivated, high beta (18~30Hz) and gamma (30~50Hz) waves were remarkably activated. The order of EEG fluctuation caused by the smell stimulus is as follows; hair smell > butyric acid > foot odor, sour smell > ammonia > sweat smell. It means that the classroom smells cause an excessive brain arousal and straining and may be reducing one's attention and learning ability.

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A Study on Repression of the Female Body as Expressed by Chinese Foot-binding and the Western Corset (전족과 코르셋에 표현된 몸의 억압에 대한 의미해석)

  • Jeong, Ki-Sung;Kim, Min-Ja
    • Journal of the Korean Society of Costume
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    • v.61 no.7
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    • pp.35-50
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    • 2011
  • In this study, repression of the body is defined as a restriction on natural developments or movements and a modification either temporarily or permanently of the human body in shape, color, texture and odor. In addition, it involves physical and (or) mental pain. Chinese foot-binding and the Western corset are extreme examples of female body's being repressed in the history of fashion. The analysis of this type of repression will be based on historical research and theoretical concepts such as Darwin's (1809-1882) survival condition, Freud's (1856-1939) renunciation of desire, Weil's (1909-1943) privilege, and Foucault's (1926-1984) L'Usage des Plaisirs(the use of pleasure). Chinese foot-binding symbolically represents ideal beauty, the distinction of an ethnic group, and a desire for improved social status in the struggle for political power. It also represents psychology and a esthetics of eroticism and fetishism that originate from a man's desire and his individual taste. Symbolically, the Western corset represents abundance and fecundity, obedience and devotion to religion, the sanctity of God and ideal beauty as defined by political power. It also represents psychology and aesthetics of eroticism and fetishism as man's desire and a fashion icon. In conclusion, Chinese foot-binding was pursuit of power in male ideology but Western corset was a power struggle between God and mankind.

The Study on the Effect of Efficient Microorganism for Early Stabilization of the Burial Sites (매몰지 조기 안정화를 위한 유용 미생물의 효과에 관한 연구)

  • Kim, Hyun-Sook;Park, Sujung;Jheong, Weonhwa;Srinivasan, Sathiyaraj;Lee, Sang-Seob
    • Korean Journal of Microbiology
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    • v.49 no.4
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    • pp.343-352
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    • 2013
  • In this study, we have evaluated the effect of efficient microorganisms on odor-removal efficiency and early stabilization of the burial sites. We have developed an efficient microorganism designated as 'KEM' which have the ability to degrade organic compounds and remove odor effectively. Other efficient microorganisms already used on site, such as EM and Bacillus sp., were also compared. We preceded these experiment using lab-scale reactors under three conditions (control, only media and only body) and comparing the effect of with or without the application of tree efficient microorganisms separately. Analysis was focused on eight components (ammonia, TMA, $H_2S$, methyl mercaptan, dimethyl sulfide, dimethyl disulfide, $CO_2$ and $CH_4$), and as a result, efficient microorganisms were shown efficiency in the removal of ammonia and methyl mercaptan. The applied KEM decayed up to 71.2% of the buried meat. We were unable to observe significant differences in microbial communities between efficient microorganisms-treated and non-treated reactors due to the large presence of microorganisms in both soil and carcasses. However, it was possible to observe the effect on odor control and decay rate through the application of efficient microorganisms.

Effect of Corynebacterium glutamicum and Bacillus licheniformis on livestock material burial treatment (매몰된 가축 사체의 부패 촉진 및 토양 비옥화를 위한 Corynebacterium glutamicum과 Bacillus licheniformis 처리 효과)

  • Shin, You-Jeong;Heo, Geon-Young;Kim, Ju-Hyung;Kim, Bit-Na;Min, Jiho;Cho, Ho-Seong
    • Korean Journal of Veterinary Service
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    • v.40 no.1
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    • pp.53-59
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    • 2017
  • Foot and mouth disease (FMD) is highly infectious disease of cloven-hoofed animals, particularly problematic in cattle, sheep, pigs and goats for economic reasons. Last FMD outbreak in February, 2017 caused tremendous social and economical impacts. The Korean FMD policy aims to vaccinate intact animals and euthanize and bury infected animals to prevent the disease spread. However, there was a problem that the buried livestock did not decompose after several years. Therefore, the study was purposed to investigate the effect of Corynebacterium glutamicum and Bacillus licheniformis on the degradation of buried cow carcasses and on the soil condition; such as temperature, decomposition course of carcasses, composition of amino acids in the soil around carcasses, and plant root elongation to measure soil conditions. As a result, the composition of amino acids in the soil treated with C. glutamicum and B. licheniformis was generally higher than those in the untreated soil. Plant roots in soil treated with C. glutamicum and B. licheniformis grew longer than in non-treated soil. The results suggested that the toxic effect on a grave land buried with FMD infected livestock is reduced when treated with C. glutamicum and B. licheniformis in regard of odor reduction, promoted decaying process, and soil fertilization.

Study of Anti-microbe Activity of Essential oil(Unshiu oil) purified from Citrus Unshiu S.Marcov (감귤에서 분리한 정유 성분의 항균활성 연구)

  • Jeoung, See-Hwa;Gim, Seon-Bin;Choi, Hak-Joo;Kim, Dong-Hee
    • Journal of Haehwa Medicine
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    • v.20 no.2
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    • pp.67-78
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    • 2012
  • Volatile odor substance originating from drying and making dry peel of tangerine from the fruit skin were collected through modern equipment. The anti-microbial activity of the substance against various skin-residing bacteria including acne, dandruff, athelete's foot, and gingivitis inducing microorganisms were tested. Anti-microbial activity was observed in purified oil, where 87 to 92% was D-limonene. Against P. acnes, 103$cfu/m{\ell}$ of P. acnes were suppressed at 0.1% Unshiu oil, and the MIC was measured to be 0.3%. Against P. ovale, a dandruff inducing bacteria, 104$cfu/m{\ell}$were suppressed at 0.1% Unshiu oil, and the MIC was measured to be 0.1%. Against T. rubrum and T. Mentagrophytes, both of which are athelete's foot inducing microorganisms, 83% of T. Mentagrophytes and 99.9% of T. rubrum were suppressed at 0.1% Unshiu oil, and the MIC were 0.3% and 0.05% respectively. Against S. aureus, a skin infection inducing bacteria, 103$cfu/m{\ell}$ of the bacteria were suppressed at 0.1% Unshiu Oil. Against B. subtilis, a non-pathogenic sporulating bacteria, 104$cfu/m{\ell}$ of the bacteria were suppressed at 0.1% Unshiu Oil. Against C. albicans, found in mucous membranes, 104$cfu/m{\ell}$ of the bacteria were suppressed at 0.1% Unshiu Oil. Against Aspergillus niger, an otomycosis inducing microorganism, 99.9% were suppressed at 0.1% Unshiu Oil. The results above indicate that low concentration of purified oil extracted from tangerine had strong antimicrobial activities against bacteria and fungi residing on the skin, and that it may be developed into skin disorder treating products in the future.

The Effect of Soil Characters on Removal of Odorous Gases during Carcasses Degradation with Efficient Microorganisms (토질 특성에 따른 가축사체 매몰지의 악취 저감 연구)

  • Kim, Hyun-Sook;Park, Sujung;Jung, Weon Hwa;Srinivasan, Sathiyaraj;Lee, Sang-Seob
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.4
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    • pp.277-285
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    • 2014
  • The usage of efficient microorganism (EM) is increasing in concern for server purposes including odor removal during carcasses degradation. In this study, we have studied the type of soil and its effect on efficient microorganisms for the removal of odorous gases during buried carcasses degradation in lab-scale reactor. The carcasses are buried in the reactor with various soil types such as normal soil, 20% sandy and 20% clay soil with the efficient microorganism KEM. The efficient microorganisms KEM have the ability to stabilize the degradation of carcasses of the burial site. We have focused on the analysis of odorous gases such tri-methylamine (TMA), hydrogen sulfide ($H_2S$), methyl mercaptan (MM), dimethyl sulfide (DMS), dimethyl disulfide (DMDS), carbon dioxide ($CO_2$), and methane ($CH_4$) along with the changes of microbial community changed during complete degradation of buried carcasses for a year. The results suggested that the 20% sandy soil contain lesser level of $H_2S$ and MM (0.09 and 0.35 mg) but 20% clay has higher nitrogen compound removing effect and leave only less amount of ammonia and TMA (0.31 and 2.06 mg). The 20% sandy soil also has the ability to breakdown the carcasses more quality compared with other types of soil. Based on the data obtained in this study suggesting that, the use of 20% sandy soil can effectively control sulfur compounds whereas 20% clay soil controls nitrogen compounds in the buried soil. Depending on the type of the soil, the dominant of microbial communities and the distribution was change.

Concentrations of metavolite in the leachate from pilot scale burial (실험용 매몰지 침출수의 대사체물질 농도변화)

  • Jeon, Tae-Wan;Park, Ho-Yeun;Hwang, Dong-Gun;Kang, Young-Yeul;Kim, Yong-Jun;Jang, Mi-Jeong;Shin, Sun-Kyoung
    • Analytical Science and Technology
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    • v.31 no.5
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    • pp.185-194
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    • 2018
  • At the end of November 2010, livestock infected with foot and mouth disease (FMD) were buried, increasing concern about secondary pollution of drinking water and groundwater with odor. Hence, measures to reduce pollution of drinking water and groundwater are needed. In this study, based on livestock type and soil texture, five pilot-scale burial sites were monitored for the past three years from Feb 2012 to 2015. Leachate from the site was analyzed for 90 compounds. A detailed investigation has been completed, looking into organic matter decomposition characteristics of the buried bodies, relevant trace elements thereof, and in particular metabolite concentration changes such as the degree of decomposition of a carcass. From the results, no detectable heavy metals, including cadmium and arsenic, were measured. Among animal types, the rate of cattle decomposition is faster than swine decomposition, and the decomposition of the bodies were performed in sequence from sand, clay loam, sandy loam.