• 한국식품위생안전성학회지
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• 제6권2호
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• pp.79-81
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• 1991

1990년 5우러 23일 27열의 식중독이 보고되었다. 그들은 미국 New Jersey 주의 Gergen Country에 있는 한 회사의 개업기념 야유회에 참석한 직원과 가족들 중 일부였다. 섭취한 음식에 대한 설문조사로 ziti 가 전파매체였던 것으로 생각되었다. (Chi Square 9.05) 잠복기는 9시간, 증세 시속시간은 평균 24시간이었다. 대변검사결과 Clostridium perfringens와 엔테로톡신이 분리되었다.

• Archives of Pharmacal Research
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• 제28권6호
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• pp.716-721
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• 2005

Fluoxetine is an anorexic agent known to reduce food intake and weight gain. However, the molecular mechanism by which fluoxetine induces anorexia has not been well-established. We examined mRNA expression levels of neuropeptide Y (NPY) and proopiomelanocortin (POMC) in the brain regions of rats using RT-PCR and in situ hybridization techniques after 2 weeks of administering fluoxetine daily. Fluoxetine persistently suppressed food intake and weight gain during the experimental period. The pair-fed group confirmed that the reduction in body weight in the fluoxetine treated rats resulted primarily from decreased food intake. RT-PCR analyses showed that mRNA expression levels of both NPY and POMC were markedly reduced by fluoxetine treatment in all parts of the brain examined, including the hypothalamus. POMC mRNA in situ signals were significantly decreased, NPY levels tended to increase in the arcuate nucleus (ARC) of fluoxetine treated rats (compared to the vehicle controls). In the pair-fed group, NPY mRNA levels did not change, but the POMC levels decreased (compared with the vehicle controls). These results reveal that the chronic administration of fluoxetine decreases expression levels in both NPY and POMC in the brain, and suggests that fluoxetine-induced anorexia may not be mediated by changes in the ARC expression of either NPY or POMC. It is possible that a fluoxetine raised level of 5-HT play an inhibitory role in the orectic action caused by a reduced expression of ARC POMC ($\alpha$-MSH).

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2014년도 추계학술대회
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• pp.135-137
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• 2014

스마트폰의 대중화와 교통카드의 확대에 따라서 NFC 기술에 대한 사회적인 관심이 증대되고 있다. 대부분의 NFC의 활용이 전자 상거래에 집중이 되고 있고, 이에 대한 보안의 문제점이나 현재의 기술적인 화두를 이루고 있지만 콘텐츠 산업과 연결한 새로운 부가가치 창출에 대한 논의는 미약하다. 현 정부에서 소상공인 지원 사업으로 차량 개조를 통한 Food Truck의 개조와 사업에 대한 규제를 완화하게 됨으로서 Food Truck에 대한 관심이 높아지고 있으나 주문이 밀리는 점심시간이나 저녁에 효율적인 주문관리 체계구축을 위한 NFC를 활용한 주문시스템에 관한 모델을 본 연구에서 제시하고자 한다. 본 연구에서 활용한 S-Guide 시스템은 인터넷의 연결이 필요 없이 공유기와 서버가 하나로 묶인 인트라넷 성향의 서버시스템으로서 NFC의 활용도가 높은 Food Truck을 운영하는 소상공인에게 적합한 시스템으로 경영의 효율성에 많은 기여를 할 것으로 판단된다.

• Toxicological Research
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• 제16권4호
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• pp.269-274
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• 2000

Epoxidised soya bean oil (ESBO, 1000, 2000 or 4000 mg/kg) was orally administered to BALB/c mice daily for 28 consecutive days, and the control mice were exposed to vehicle (corn oil). Mice were immunized and challenged with sheep red blood cells (SRBC) or bovine serum albumin (BSA). In groups exposed to ESBO, the body weight gains and the relative lymphoid organ weights were not significantly changed as compared with control group. Secondary IgG antibody response to BSA was not significantly changed by ESBO, but plaque-forming cell (PFC) response to SRBC was significantly suppressed in mice treated with 4000 mg ESBO/kg/day. The mitogenic response of splenic B cells induced by LPS was not effected by ESBO in any of the groups. These results indicate that ESBO did not induce significant humoral immune response at a dose less than 2000 mg/kg/day in mice.

• 한국환경보건학회지
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• 제33권5호
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• pp.379-385
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• 2007

This study was aimed to investigate the estrogenic activity of Di-(2-ethylhexyl) adipate (DEHA) using immatured type uterotrophic assay. SD rats were treated with DEHA (40, 200, 1000mg/kg/day), estradiol-3-benzoate (EB) $(1{\mu}g/kg/day)$ as positive control on the assay. In immatured-type uterotrophic assay, relative organ weights of kidney and reproductive organs such as ovary at high-dose group were significantly increased compared to those of vehicle control group. DEHA did not influence the levels of serum FSH and LH, and uterine morphological changes such as luminal epithelial height, myometrial thickness and numbers of uterine gland, and BrdU indices. In these results, there was no significant variation by DEHA treatment, suggesting that DEHA appears not to be a endocrine disrupter with estrogenic activity.

• Biomolecules & Therapeutics
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• 제20권2호
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• pp.234-238
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• 2012

Propofol is an anesthetic commonly used to provide sedation or to induce and maintain an anesthetic stated. However, there are reports which indicate propofol may cause psychological dependence or be abused. In the present study, we used various behavioral tests including climbing test, jumping test, conditioned place preference, and self-administration test to assess the dependence potential and abuse liability of propofol compared to a positive control (methamphetamine) or a negative control (saline or intralipid). Among the tests, the conditioned place preference test was conducted with a biased method, and the selfadministration test was performed under a fixed ratio (FR) 1 schedule, 1 h per session. No difference was found in the climbing test and jumping test, but propofol (30 mg/kg, i.p.) increased the rewarding effect in the conditioned place preference test, and it showed a positive reinforcing effect compared to the vehicle. These results indicate that propofol tends to show psychological dependence rather than physical dependence, and it seems not to be related with dopaminergic system.

• 대한수의학회지
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• 제48권3호
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• pp.327-336
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• 2008

Many herbal extracts have been reported to have a preventive or therapeutic effect of on diabetes mellitus. Momordica Charantia commonly known as bitter melon or karela has been reported to be a medicinal plant for treating various diseases including cancers and diabetes. The objectives of this study were to investigate anti-diabetic effects of bitter melon (BM) as determined by blood glucose levels, glucose tolerance test (GTT), insulin tolerance test (ITT), insulin and HbA1C activities in serum, serum biochemical and lipid levels, histopathology, immunohistochemistry and AMPK-${\alpha}2$ expression of skeletal muscle in male C57BL/6J db/db mice. There were four experimental groups including vehicle control, BM 10 mg/kg, BM 50 mg/kg, and BM 250 mg/kg. BM at doses of 10, 50, and 250 mg/kg was orally administered to the diabetic mice everyday for 8 weeks. The treatments of BM 10, 50, and 250 mg/kg significantly decreased the blood glucose level in the diabetic mice compared with vehicle control (p < 0.05). The treatments of BM 10 and 50 mg/kg significantly decreased the GTT, ITT and HbA1c levels in the diabetic mice compared with vehicle control (p < 0.05). All BM groups significantly decreased GOT, GPT, BUN, LDL and glucose levels in the diabetic mice compared with the vehicle control mice (p < 0.05). The livers of mice treated with the BM 10, 50, and 250 mg/kg showed a remarkable decrease in the number of lipid droplets compared with the vehicle control. The pancreas of mice treated with the BM 10, 50, and 250 mg/kg showed a remarkable increase in insulin concentration of ${\beta}$-cells compared with the vehicle control. In addition, the treatments of BM 10, 50, and 250 mg/kg actually increased the expression of AMPK-${\alpha}2$ compared with vehicle control. These results suggest that BM has a respectable anti-diabetic effect resulting from inhibition of blood glucose level and lipid level in serum and that consumption of BM may give a benefit for controlling diabetes mellitus in humans.

• 한방재활의학과학회지
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• 제18권4호
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• pp.13-24
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• 2008

Objectives : The purpose of this study was to investigate the effect of Poncirus Trifoliata(PT) on improvement of fecal impaction in spinal cord injured(SCI) rats. Methods : Fifteen adult Sprague-Dawley female rats were used weighing 200~250 g. A complete spinal cord transection was performed surgically at the T10 cord level. Experimental groups were assigned into 3 groups: Control(n=5), SCI+vehicle(n=5) and SCI+PT(n=5). PT was administered 100mg/kg in 0.5ml every 24 hours from 1st operation day to 7th day. We measured the body weight and food intake as well as the number and the weight of fecal pellet every morning. After 1 week of operation, whole colon was divided into proximal and distal segments under anesthesia. Each segment of colon was mounted with longitudinal direction in a organ bath. We measured spontaneous contraction and compared the area under the curve in each segments. Enhanced responses were observed by acetylcholine($10^{-6}M$), 40 mM KCl solution, L-NAME($10^{-4}M$). Results : The fecal number and weights were significantly higher in the group of SCI+PT than SCI+vehicle group(p<0.05). In organ bath study, area under the curves of the spontaneous contraction in SCI+vehicle and SCI+PT groups were significantly increased compared to control group. Contractility of distal colon in response to acetylcholine or KCl in SCI+vehicle group was significantly decreased compared to other groups(p<0.05). Conclusions : These results suggest that PT might be useful to promote bowel emptying in spinal cord injured rats.

• Food Science and Biotechnology
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• 제17권5호
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• pp.1025-1031
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• 2008

S-Adenosyl-L-methionine (SAM) exerts several beneficial effects on depression, chronic diseases, and cognitive impairments. Bifidobactrium bifidum BGN4 reportedly produces higher amounts of SAM than any other lactic acid bacterium used in yogurt. The aim of this study was to develop a SAM-reinforced probiotic yogurt using Bifidobacterium. The sensory aspects of the yogurt via response surface methodology (RSM) and the texture and SAM content of the yogurt were assessed. Based on the sensory assessments for sweetness, sourness, and thickness evaluated by 48 panelists, the optimized conditions for preparation of SAM-reinforced yogurt were 4.0-4.4%(w/w) sugar, 3.2-3.5%(w/w) skim milk, and a pH of 4.7-4.8. The SAM content of the developed yogurt was 0.05 nmol/mL. In conclusion, SAM-reinforced probiotic yogurt may provide a vehicle for the potential exploitation of the benefits of increased dietary SAM.

• 한국콘텐츠학회논문지
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• 제14권11호
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• pp.944-954
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• 2014

이 글은 자본주의 사회에서 전통음식이 과거에 대한 "향수"를 자극하며 재창조되고 소비되는 방식에 대해 논의한다. 이 글은 사찰음식과 안동음식이 재탄생한 과정 등의 사례 분석을 통해 오늘날 전통음식이 상품화되는 과정에서 탈맥락화의 과정을 거친다고 주장한다. 또한 고대 중국 사회에서 채식문화가 불교문화의 일부로 인정받기 시작한 과정을 되짚으며 불교의 채식문화가 여러 환경요인에 의해 발명된 문화라는 점을 밝히려 한다. 고대 중국사회에서 채식문화가 불교사상을 전파하기 좋은 도구로 자리 잡았다면 오늘날 사찰음식은 불교사상의 전파보다는 상품화와 소비를 가능하게 하고 있다. 이 논문은 현대 한국사회에서 전통음식이 다시 인기를 끌고 있는 현상에 초점을 맞추어 이와 같은 현상이 현대 한국사회의 소비자들의 심리와 요구를 어떻게 반영하는가를 살펴본다. 그리고 현대 한국사회에서 각광을 받고 있는 전통음식 문화가 자본주의 사회 내에서 대항문화로서 자리매김할 수 있을지에 대해 논의한다.