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Development of S-Adenosyl-L-methionine (SAM)-reinforced Probiotic Yogurt Using Bifidobacterium bifidum BGN4  

Kim, Ji-Youn (Department of Food and Nutrition, Research Institute of Human Ecology, College of Human Ecology, Seoul National University)
Seo, Han-Seok (Department of Food and Nutrition, Research Institute of Human Ecology, College of Human Ecology, Seoul National University)
Seo, Min-Jeong (Department of Food and Nutrition, Research Institute of Human Ecology, College of Human Ecology, Seoul National University)
Suh, Joo-Won (Department of Biological Science, Institute of Bioscience and Biotechnology, Myongji University)
Hwang, In-Kyeong (Department of Food and Nutrition, Research Institute of Human Ecology, College of Human Ecology, Seoul National University)
Ji, Geun-Eog (Department of Food and Nutrition, Research Institute of Human Ecology, College of Human Ecology, Seoul National University)
Publication Information
Food Science and Biotechnology / v.17, no.5, 2008 , pp. 1025-1031 More about this Journal
Abstract
S-Adenosyl-L-methionine (SAM) exerts several beneficial effects on depression, chronic diseases, and cognitive impairments. Bifidobactrium bifidum BGN4 reportedly produces higher amounts of SAM than any other lactic acid bacterium used in yogurt. The aim of this study was to develop a SAM-reinforced probiotic yogurt using Bifidobacterium. The sensory aspects of the yogurt via response surface methodology (RSM) and the texture and SAM content of the yogurt were assessed. Based on the sensory assessments for sweetness, sourness, and thickness evaluated by 48 panelists, the optimized conditions for preparation of SAM-reinforced yogurt were 4.0-4.4%(w/w) sugar, 3.2-3.5%(w/w) skim milk, and a pH of 4.7-4.8. The SAM content of the developed yogurt was 0.05 nmol/mL. In conclusion, SAM-reinforced probiotic yogurt may provide a vehicle for the potential exploitation of the benefits of increased dietary SAM.
Keywords
S-adenosyl-L-methionine; response surface methodology (RSM); Bifidobactrium bifidum BGN4; sensory acceptance; yogurt;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By Web Of Science : 1  (Related Records In Web of Science)
Times Cited By SCOPUS : 0
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1 WHO. Part 1. Ten Statistical Highlights in Global Public Health. World Health Statistics 2007. World Health Organization, Geneva, Switzerland. p.16 (2007)
2 Bottiglieri T, Hyland K. S-Adenosylmethionine levels in psychiatric and neurological disorders: A review. Acta Neurol. Scand. (Suppl.) 154: 19-26 (1994)
3 Lu SC, Mato JM. Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer. Alcohol 35: 227-234 (2005)   DOI   ScienceOn
4 Bradley JD, Flusser D, Katz BP, Schumacher HR Jr, Brandt KD, Chambers MA, Zonay LJ. A randomized, double blind, placebo controlled trial of intravenous loading with S-adenosylmethionine (SAM) followed by oral SAM therapy in patients with knee osteoarthritis. J. Rheumatol. 21: 905-911 (1994)
5 Kim H, Lee SY, Ji GE. Timing of Bifidobacterium administration influences the development of allergy to ovalbumin in mice. Biotechnol. Lett. 27: 1361-1367 (2005)   DOI   ScienceOn
6 Kim N, Kunisawa J, Kweon M-N, Ji GE, Kiyono H. Oral feeding of Bifidobacterium bifidum (BGN4) prevents $CD4^+$ $CD45RB^{high}$ T cell-mediated inflammatory bowel disease by inhibition of disordered T cell activation. Clin. Immunol. 123: 30-39 (2007)   DOI   ScienceOn
7 Kim KH, Shin WC, Park YS, Yoon SS. In situ detection and differential counts of Bifidobacterium spp. using bromocresol green, a pH-dependent indicator. Food Sci. Biotechnol. 16: 99-103 (2007)   과학기술학회마을
8 Shaker RR, Jumah RY, Abu-Jdayil B. Rheological properties of plain yogurt during coagulation process: Impact of fat content and preheat treatment of milk. J. Food Eng. 44: 175-180 (2000)   DOI   ScienceOn
9 Yazici F, Akgun A. Effect of some protein based fat replacers on physical, chemical, textural, and sensory properties of strained yoghurt. J. Food Eng. 62: 245-254 (2004)   DOI
10 Saint-Eve A, Martin N, Levy C, Souchon I. How can protein ratio affect aroma release, physical properties, and perceptions of yoghurt? Dev. Food Sci. 43: 391-394 (2006)   DOI
11 Haque A, Richardson RK, Morris ER. Effect of fermentation temperature on the rheology of set and stirred yogurt. Food Hydrocolloid 15: 593-602 (2001)   DOI   ScienceOn
12 Akin MB, Akin MS, Kirmaci Z. Effects of inulin and sugar levels on the viability of yogurt and probiotic bacteria and the physical and sensory characteristics in probiotic ice-cream. Food Chem. 104: 93-99 (2007)   DOI   ScienceOn
13 Afonso IM, Maia JM. Rheological monitoring of structure evolution and development in stirred yoghurt. J. Food Eng. 42: 183-190 (1999)   DOI   ScienceOn
14 Kalviainen N, Roininen K, Tuorila H. The relative importance of texture, taste, and aroma on a yogurt-type snack food preference in the young and the elderly. Food Qual. Prefer. 14: 177-186 (2003)   DOI   ScienceOn
15 Logan AC, Katzman M. Major depressive disorder: Probiotics may be an adjuvant therapy. Med. Hypotheses 64: 533-538 (2005)   DOI   ScienceOn
16 Kim H, Kwack K, Kim DY, Ji GE. Oral probiotic bacterial administration suppressed allergic responses in an ovalbumininduced allergy mouse model. FEMS Immunol. Med. Mic. 45: 259-267 (2005)   DOI   ScienceOn
17 Mato JM, Lu SC. Role of S-adenosyl-L-methionine in liver health and injury. Hepatology 45: 1306-1312 (2007)   DOI   ScienceOn
18 Bottiglieri T, Godfrey P, Flynn T, Carney MW, Toone BK, Reynolds EH. Cerebrospinal fluid S-adenosylmethionine in depression and dementia: Effects of treatment with parenteral and oral Sadenosylmethionine. J. Neurol. Neurosurg. Ps. 53: 1096-1098 (1990)   DOI
19 Morelli V, Naguin C, Weaver V. Alternative therapies for traditional disease states: Osteoarthritis. Am. Fam. Physician 67: 339-344 (2003)
20 Bottiglieri T, Hyland K, Reynolds EH. The clinical potential of ademethionine (S-adenosylmethionine) in neurological disorders. Drugs 48: 137-152 (1994)   DOI   ScienceOn
21 Mohameed HA, Abu-Jdayil B, Al-Shawabkeh A. Effect of solids concentration on the rheology of labneh (concentrated yogurt) produced from sheep milk. J. Food Eng. 61: 347-352 (2004)   DOI   ScienceOn
22 Morrison LD, Smith DD, Kish SJ. Brain S-adenosylmethionine levels are severely decreased in Alzheimer's disease. J. Neurochem. 67: 1328-1331 (1996)   DOI   ScienceOn
23 Cassano P, Fava M. Depression and public health: An overview. J. Psychosom. Res. 53: 849-857 (2002)   DOI   ScienceOn
24 Karnovsky MJ. A formaldehyde-glutaraldehyde fixative of high osmolarity for use in electron microscopy. J. Cell Biol. 27: 137A-138A (1965)
25 Sodini I, Remeuf F, Haddad S, Corrieu G. The relative effect of milk base, starter, and process on yogurt texture: A review. Crit. Rev. Food Sci. 44: 113-137 (2004)   DOI   ScienceOn
26 Williams AL, Girard C, Jui D, Sabina A, Katz DL. SAdenosylmethionine (SAMe) as treatment for depression: A systematic review. Clin. Invest. Med. 28: 132-139 (2005)
27 Gorman JM. Gender differences in depression and response to psychotropic medication. Gend. Med. 3: 93-109 (2006)   DOI   ScienceOn
28 Fetrow CW, Avila JR. Efficacy of the dietary supplement Sadenosyl-L-methionine. Ann. Pharmacother. 35: 1414-1425 (2001)   DOI   ScienceOn
29 You HJ, Oh DK, Ji GE. Anticancerogenic effect of a novel chiroinositol-containing polysaccharide from Bifidobacterium bifidum BGN4. FEMS Microbiol. Lett. 240: 131-136 (2004)   DOI   ScienceOn
30 Mischoulon D, Fava M. Role of S-adenosyl-L-methionine in the treatment of depression: A review of the evidence. Am. J. Clin. Nutr. 76: 1158-1161 (2002)   DOI
31 Kim JY, Suh JW, Ji GE. Evaluation of S-adenosyl-L-methionine production by Bifidobacterium bifidum BGN4. Food Sci. Biotechnol. 17: 184-187 (2008)   과학기술학회마을