• Environmental Analysis Health and Toxicology
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• v.11 no.3_4
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• pp.65-68
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• 1996

Selaginellae Herba has been used as folk medicine for antineoplastics, coagulants, antidotes and invigorants. To find an in vitro screening method for liver protective effect of Selaginellae Herba in benzo(a)pyrene intoxicated injury were examined in primary cultured rat hepatocytes. Using MTT assay, herba concentration showed dose dependently viability. The lowest concentration of benzo(a)pyrene giving cytotoxicity revealed around 50gM. The hepatoprotective effect of Selaginellae Herba in both water and chloroform extracts was also increased dose dependently.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.370.4-371
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• 2002

The roots of Juglans mandshurica Maximowicz (Juglandaceae) have been used as a folk medicine for treatment of cancer in Korea. Several naphthoquinones and naphthalenyl glucosides from Juglans species have been reported (1-7). In the course of isolating cytotoxic compounds from the roots of this plant. we have isolated six naphthalene glycosides. four tetralone, one naphthalene carboxylic acid glucoside and nine diarylheptanoids (8-13). (omitted)

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.299.3-300
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• 2002

Both of Semen (OF-Se) or stem (OF-Sf) of Opuntia ficus-indica Semen have been used as a healthful food or folk medicine in korea for the treatment of asthma. diabetes mellitus. aging, osteoporosis, rheumatic arthritis. constipation, cancer. gastric ulcer. constipation. toxic state, edema, etc, There are many reports that OF have the anti-gastric damage, wound healing, diabetes mellitus, monoamine oxidase B inhibitor etc. (omitted)

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.404.3-405
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• 2002

Cupressaceae plants are used in traditional folk medicine. whose extracts have been found to possess some bioactivities. (－)-Yatein is a lignan of the dibenzyl-butyrolactone type. that has been isolated from some Cupressaceae plants. It was reported that (－)-yatein. isolated from plants. showed different activities from the synthetic yatein ［3］. Hence. the enantiosetective determination of yatein from synthetic materials and natural products would be necessary. (omitted)

• YAKHAK HOEJI
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• v.53 no.5
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• pp.298-302
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• 2009

Mume Fructus extract is used in folk medicine in Eastern Asian countries including Korea. However, its therapeutic effect on thrombosis is not known. Mume Fructus methanol extract (ME) dose-dependently inhibited ADP-induced platelet aggregation and also exhibited about 130% fibrinolytic activity compared to the natto. Oral administration of ME to mice significantly extended tail-bleeding time. ME prolonged both aPTT and PT in human citrated plasma also. These results suggest that the methanol extract from Mume Fructus have antithrombosis activity.

• YAKHAK HOEJI
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• v.32 no.4
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• pp.281-286
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• 1988

For the investigation of medicinal resources in Hydrocotyle species, the studies were conducted to evaluate the pharmaco-constituents in Hydrocotyle japonica MAKINO (Umbelliferae), which is used as folk medicine in Korea. From the methyl alcohol extract of the whole plant, $isorhamnetin-3-O-{\beta}-D-galactoside$ ($C_{22}H_{22}O_{12}{\cdot}1/3H_2O$, bright yellow needle crystal, mp $247{\sim}248^{\circ}C$, $[{\alpha}]_D^{28}^{\circ}=-52.27^{\circ}$ in pyridine), one of three flavonol substances in extrat, was isolated and identified by physicochemical properties and spectroscopic evidences (UV, IR, NMR and MS etc.,) in comparison with authentic sample. This flavonoid was appeared from Hydrocotyle japonica MAKINO through phytochemical approaches at the outset.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.8
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• pp.1799-1804
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• 2012

Anti-Pseudomonas aeruginosa activities for ethanol extract of 34 medicinal plants widely used in the folk medicine were evaluated to screening of anti-Pseudomonas aeruginosa agents. The ethanol extracts of Gardenia jasminoides, Arctium lappa, Citrus unshiu, and Phellodendron amurense showed antimicrobial activities against P. aeruginosa ATCC 27853. The ethanol extracts of Gardenia jasminoides among these medicinal plants showed significant antimicrobial activity against P. aeruginosa. Therefore, we expect that these medicinal plants will be useful for nature antimicrobial agent against P. aeruginosa in future.

• Biomedical Science Letters
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• v.19 no.3
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• pp.224-232
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• 2013

Cucurbitacins are a natural cell-permeable triterpenoid compound isolated from Cucurbitaceae and Cruciferae. Cucurbitacins have been used as folk medicine because of their anti-inflammatory and analgesic effects. In the present study, we investigate the anti-cancer effects of cucurbitacin I on colitis-associated colon carcinogenesis induced by azoxymethane (AOM)/dextran sodium sulfate (DSS) in BALB/c mice. Cucurbitacin I treatment attenuated loss of body weight and decreased the number of colon tumors. Western blot analysis showed that cucurbitacin I treatment significantly inhibited the protein expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor (TNF)-${\alpha}$ and interleukin (IL)-6. These results suggest that cucurbitacin I suppressed inflammatory reaction and tumor development in colitis-associated colon carcinogenesis.

• Korean Journal of Pharmacognosy
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• v.33 no.3 s.130
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• pp.230-237
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• 2002

Prickly pear(Opuntia ficus-indica var saboten Makino, Cactaceae) is widely used as folk medicine for burned wound, edema and indigestion. To confirm the hypolipidemic action of the extract from Cactus stem and fruit in dietary hyperlipidemic rats, variations of the lipid- or cholesterol-related components were investigated. As results these changes were significantly prevented by treatments with Cactus extracts. The effects of the extract of fruit was better than those of stem.

• Korean journal of food and cookery science
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• v.12 no.1
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• pp.115-121
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• 1996

Ixeris dentata Nakai (Compositae) is a perennial herb and the young shoots when prepared properly are edible as a bitter appetizing vegetable in the early spring. The whole plant has been used as a folk medicine in treating diabetes in Korea. As a part of our studies on bitter substances, we have investigated the bitterness of the plant through a taste-guided fractionation method. Bitter substances were extracted by the solvent fractionation and the bitterness was evaluated by 10 trained panelists consisted with graduate students of Dept. of Foods and Nutrition. It has been revealed that the bitter compounds were distributed throughout the extracting fractions and the higher intensity of the bitterness was seen in the n-BuOH fractions. The bitter compounds were subfractionated by the silica gel column chromatography and the bitterness was evaluated by the trained panelists. The subfractions which were indicated as the bitter compounds will be further studied to isolate the compounds. The H$_2$O fractions were grouped according to the molecular weight through the ultrafiltration and the group with 1,000 < m.w. < 30,000 was evaluated as the most intense bitter subfraction.