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The Effects of Mume Fructus Extracts on Blood Flow Improvement  

Park, Seung-Hee (R&D Center, Jung San Biotechnology)
Park, Keum-Ju (R&D Center, Jung San Biotechnology)
Kim, Jae-Ki (R&D Center, Jung San Biotechnology)
Publication Information
YAKHAK HOEJI / v.53, no.5, 2009 , pp. 298-302 More about this Journal
Abstract
Mume Fructus extract is used in folk medicine in Eastern Asian countries including Korea. However, its therapeutic effect on thrombosis is not known. Mume Fructus methanol extract (ME) dose-dependently inhibited ADP-induced platelet aggregation and also exhibited about 130% fibrinolytic activity compared to the natto. Oral administration of ME to mice significantly extended tail-bleeding time. ME prolonged both aPTT and PT in human citrated plasma also. These results suggest that the methanol extract from Mume Fructus have antithrombosis activity.
Keywords
Platelet; Mume Fructus; antithrombosis; fibrinolysis; anticoagulant;
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Times Cited By KSCI : 2  (Citation Analysis)
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