• 제목/요약/키워드: fluorinated

검색결과 314건 처리시간 0.025초

PHARMACOLOGICAL EFFECTS OF NOVEL QUINOLINEDIONE COMPOUNDS ON INHIBITION OF DRUG-INDUCED RELAXATION OF RAT AORTA AND THEIR PUTATIVE ACTION MECHANISM

  • Lee, Jung-Ah;Ryu, Chung-Kyu;Chung, Jin-Ho;Kim, Hwa-Jung
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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    • pp.131-131
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    • 2001
  • Two 6-(fluorinated-phenylamino)-5, 8-quinolinedione derivatives, OQ21 and OQ1, were newly synthesized as potent inhibitors of endothelial-dependent vasorelaxation. The purpose of the present study was to investigate the effect of OQ21 and OQ1 on different types of vasorelaxation and to pursue their action mechanisms. (omitted)

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Stereoselective synthesis of carbocyclic analogue of Nucleocidin

  • Kim, Ji-Hee;Quan, Ying-Lin;Ko, Ok-Hyun;Hong, Joon-Hee
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.238.3-239
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    • 2003
  • Among 4'-substituted nucleosides. Nucleocidin. 4'-azido thymidine (ADRT), 4'-fluorinated carbocyclic nucleoside. and 3'-fluoro oxetanosin analogue have demonstrated a variety of biological activities. Since the cyclopentane ring of carbocyclic nucleosides can emulate the furanose moiety. a number of these compounds exhibit interesting biological activity, particularly in the areas of antiviral and anticancer chemotherapy. (omitted)

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Blue-emitting heteroleptic iridium(III) complexes based on fluorinated 2-phenyl-4-methoxypyridine

  • Lee, Seung-Chan;Kim, Young-Sik
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2008년도 International Meeting on Information Display
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    • pp.469-472
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    • 2008
  • New iridium complexes with 2-(3',5'-bis-trifluoromethylphenyl)-4-metoxypyridine [$(CF_3)_2ppyOMe$] were synthesized and characterized for blue phosphorescent materials. It was found that $Ir[(CF_3)_2ppyOMe]_2$(acac) gives blue emission at 471 nm with strong luminescence efficiency. We discuss the role played by electron withdrawing substituents and also how the ancillary ligand influences the emission peak.

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The Preparation and Reactions of Some Fluorinated Cyclobutane Carboxylic Acids

  • J. D. Park;F. E. Rogers
    • 대한화학회지
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    • 제16권3호
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    • pp.178-188
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    • 1972
  • Diethyl itaconate was found to react tetrafluoroethylene, trifluorochloroethylene, and 1,1-difluoro-2,2-dichloroethylene quite rendily at $180^{\circ}C$ to form 1-carboxy-2,2,3,3,-tetrahalo-cyclobutane ethanoic acid derivatives ${C{\underline{X_2-CF_2-CH_2-}}C-(COOEt)-CH_2COOEt$, where X is Cl or F). Diethylcitraconate failed to yeild any cycloaddition products. The Physical and Chemical properties of the above esters and their dericatives are characterized and compared with other similar ring compounds.

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Influence of the $CF_4$ Plasma Treatments on the Wettability of Polypropylene Fabrics

  • Kwon, Young-Ah
    • Fibers and Polymers
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    • 제3권4호
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    • pp.174-178
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    • 2002
  • A plasma treatment using saturated $CF_4$ gas was employed to improve the resistance of polypropylene fabrics to water wetting. The fabrics were significantly fluorinated even within a short treatment time of 30 seconds. The result of contact angle measurement indicated that such highly hydrophobic surface was considerably durable even after 150 days of aging.

New Synthetic Method of Perfluoro-Silanes for the Stable Electrolyte of Lithium Ion Battery Application

  • Koh, Kyungkuk;Sohn, Honglae
    • 통합자연과학논문집
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    • 제10권3호
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    • pp.171-174
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    • 2017
  • Non-hydrolyzable fluorinated organosilicon compounds as an eletrolyte for the application of lithium-ion batteries (LIB) are synthesized. New synthetic method for the perfluorinated organosilicon compound containing spacer such as ethyl and propyl group with cyano moiety instead of ethylene glycol to prevent hydrolysis and to promote conductivity are developed in one pot reaction with moderately high yield. Air-sensitive boron trifluoride etherate is no longer required in this reaction. The products are characterized by spectroscopic analysis.