• 제목/요약/키워드: fit similarity

검색결과 77건 처리시간 0.021초

상이한 정렬에 따른 비교분자 유사성 지수분석(CoMSIA) 방법을 이용한 새로운 2-Alkoxyphenyl-3-phenylthioisoindoline-1-one 유도체들의 살균활성에 관한 3차원적인 정량적 구조와 활성과의 관계 (Three Dimensional Quantitative Structure-Activity Relationship Analyses on the Fungicidal Activities of New Novel 2-Alkoxyphenyl-3-phenylthioisoindoline-1-one Derivatives Using the Comparative Molecular Similarity Indices Analyses (CoMSIA) Methodology Based on the Different Alignment Approaches)

  • 성낙도;윤태용;송종환;정훈성
    • 농약과학회지
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    • 제9권1호
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    • pp.26-34
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    • 2005
  • 일련의 새로운 2-alkoxyphenyl-3-phenylthioisoindoline-1-one 유도체들의 구조 변화에 의한 저항성(RPC; 95CC7303)과 감수성(SPC; 95CC7105) 고추역병 균주(Phytopthora capsici)들의 살균활성에 대한 3차원적인 정량적 구조-활성관계(3D-QSAR)를 비교분자 유사성 지수분석(CoMSIA) 방법으로 연구하였다. 그 결과, RPC 균주는 field fit 정렬시 정전기장(E)과 수소결합 받게장(A) 및 분자궤도장(LUMO)이 조합된 조건에서 모델 R5를 그리고 SPC 균주는 atom based fit 정렬시 입체장(S)과 분자궤도장(HOMO)의 조건에서 모델 S1(또는 S5)이 가장 양호한 예측성과 적합성을 나타내는($q^2=0.714{\sim}0.823$$r^2_{ncv.}=0.918{\sim}0.954$) CoMSIA 모델이었다. 또한, RPC 균주에는 LUMO (24.4%) SPC 균주에는 HOMO(13.5%) 분자 궤도장이 그리고 두 균주에 대하여 공통적으로 수소결합 받게장(A)이 살균활성에 기여하는 특성을 나타내었다. 그리고 CoMSIA 등고도 분석결과, 두 균주에 대한 선택적인 살균활성은 N-phenyl 고리상 X-치환기와 S-phenyl 고리상 R-치환기의 구조변화로 이루어질 수 있을 것으로 판단된다.

PL의 브랜드확장이 소비자태도에 미치는 영향에 관한 연구 : 모브랜드 적합도 인식 차이의 조절효과를 중심으로 (The Effect of Brand Extension of Private Label on Consumer Attitude - a focus on the moderating effect of the perceived fit difference between parent brands and an extended brand -)

  • 김종근;김향미;이종호
    • 한국유통학회지:유통연구
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    • 제16권4호
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    • pp.1-27
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    • 2011
  • 브랜드확장은 다양한 마케팅 영역 중에서도 전통적으로 활발하게 연구가 진행되어 왔던 영역으로서, 본 연구는 최근 그 중요성이나 활용도가 급증하고 있는 PL(Private Label)제품에 대해 브랜드확장의 개념을 활용하여 차별적으로 접근하고자 하였다. 최근 PL제품에 관한 마케팅연구가 활발하게 진행되고 있으나, 대부분 기존 틀에서 크게 벗어나지 못한 채 단순한 적용에 그치고 있으며, 특히 브랜드확장에 관련된 연구들에서도 PL시장의 특성을 제대로 반영하고 있다고 볼 수 없다. 특히 PL제품의 확장에 있어서는 두 가지 모브랜드가 존재할 수 있는데, 이에 대한 연구는 부재한 상황이다. 이에 본 연구에서는 확장 PL제품의 태도에 영향을 미치는 변수로서 두 가지 모브랜드인 유통업체와 기존 PL제품에 대한 태도를 제시하였다. 또한 개별 모브랜드가 PL제품의 태도에 미치는 영향은 개별 모브랜드와 확장 PL제품간 유사성에 의해 상이할 것이라고 제안하였으며, 유통업체와 기존 PL제품에 대한 태도에 영향을 미치는 변수로서 신뢰와 만족을 제시하였다. 분석결과 유통업체와 기존 PL제품에 대한 태도 모두 확장 PL제품의 태도에 유의한 영향을 미쳤으며 동시에 적합도 정도에 따라 그 영향력이 상이함도 실제 데이터를 통해 검증하였다. 즉 확장 PL제품의 태도는 모브랜드의 적합도가 보다 강하게 형성된 모브랜드의 영향을 더 크게 받는 것을 확인할 수 있었다. 이를 토대로 향후 PL제품을 확장할 경우 소비자가 보다 긍정적인 태도를 갖고 있는 모브랜드에 기초하여 해당 모브랜드와의 연상이 강하게 나타날 수 마케팅 전략을 구사할 필요가 있을 것이다.

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리더와의 접촉빈도와 심리적 거리가 직무 디스트레스에 미치는 영향: 구성원이 인지하는 셀프리더십의 매개효과 (Contact Frequency and Psychological Distance between Leaders: Job Distress and Mediation through Employees' Perceived Self-Leadership)

  • 양회창;전준호;박종록
    • 유통과학연구
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    • 제12권6호
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    • pp.41-48
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    • 2014
  • Purpose - This study aims to investigate a solution to reduce the negative reactions arising from the performance of duties or the job distress of workers in the service industry, because human resource statistics regarding workers in the service sector have been unreported, while concerns regarding exposure to emotional exertion and poor working conditions have been continuously increasing. Research design, data, and methodology - This study specifically focused on workers in highway service areas. It differs from previous studies because it involves the perspective of the person-organization fit and regards workers' cognition of leaders through the psychological distance toward the leader and the contact frequency between workers and leaders within the framework of the leader-individual fit. Moreover, this study highlights the role of the self-leadership of workers as an important factor that becomes manifested in the individual-level fit to the organization. Hence, this study investigates whether the positive role of the above factors, in turn, could reduce job distress. Workers from highway service areas in Gyeonggi-do province provided data; 141 valid questionnaires are collected. SPSS 19.0 and AMOS 19.0 were used to test the reliability and validity of constructs. Simple regression, multiple regression, and 3 step mediation tests were used to test the hypotheses after the correlation tests. Results - Results indicated that leader-member contact frequency and psychological distance have negative effects on job distress but positive effects on self-leadership. A mediation test revealed that self-leadership, in the relationships between contact frequency and job distress and between psychological distance and job distress, resulted in partial mediation and full mediation, respectively. Conclusions - The result can be understood through two different possible explanations. First, service area workers generally possess a positive perspective toward their leaders. This can be interpreted to mean that increased contact frequency and psychological distance would be considered as supports from the leader, rather than intrusive controls or management schemes. Therefore, the management in highway service areas should invest efforts in increasing contact frequency as well as maximizing psychological similarities by adopting the viewpoints of workers in terms of moral and ethical management, to reduce the workers' job distress. The results relating to self-leadership also indicate that increased contact frequency must be accompanied by intentions for the effective promotion of workers' self-leadership. It also signifies the necessity of a strategic approach by leaders to induce workers to perceive "in-group"ness as suggested both by the similarity-attraction theory and by the social identity theory. In addition, the results of the mediation test of self-leadership indicate that because workers' self-leadership activates upon increased contact frequency by the leader, it should not be a means of control and should not be utilized only from the perspective of management. It is also suggested that strategies such as transfer of authority could have a positive effect in promoting the expansion of self-influence from workers.

3차원 조형장비 선정을 위한 복합 다요소 의사결정 구조 모델 개발에 관한 연구 (A decision making framework model for the selection of a RP using hybrid multiple attribute decision making techniques)

  • 변홍석
    • 한국기계가공학회지
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    • 제7권3호
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    • pp.87-95
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    • 2008
  • The purpose of this study is to provide a decision support to select an appropriate rapid prototyping(RP) machine that suits the application of a part. Selection factors include concept model, form/fit/functional model, pattern model for molding, material property, build time and part cost that greatly affect the performance of RP machines. However, the selection of a RP is not an easy decision because they are uncertain and vague. For this reason, the aim of this research is to propose hybrid multiple attribute decision making approaches to effectively evaluate RP machines. In addition, because subjective considerations are relevant to selection decision, a fuzzy logic approach is adopted. The proposed selection procedure consists of several steps. First, we identify RP machines that the users consider. After constructing the evaluation criteria, we calculate the weights of the criteria by applying the fuzzy Analytic Hierarchy Process(AHP) method. Finally, we construct the fuzzy Technique of Order Preference by Similarity to Ideal Solution(TOPSIS) method to achieve the ranking order of all machines providing the decision information for the selection of RP machines.

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3D-QSAR Studies of Tetraoxanes Derivatives as Antimalarial Agents Using CoMFA and CoMSIA Approaches

  • Liang, Taigang;Ren, Luhui;Li, Qingshan
    • Bulletin of the Korean Chemical Society
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    • 제34권6호
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    • pp.1823-1828
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    • 2013
  • Tetraoxanes (1,2,4,5-tetraoxanes) have been reported to exhibit potent antimalarial activity. In the present study, the three dimensional-quantitative structure activity relationship (3D-QSAR) studies were performed on a series of tetraoxanes derivatives using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) techniques. The best predictive CoMFA model with atom fit alignment resulted in cross-validated coefficient ($q^2$) value of 0.719, non-cross-validated coefficient ($r^2$) value of 0.855 with standard error of estimate (SEE) 0.335. Similarly, the best predictive CoMSIA model was derived with $q^2$ of 0.739, $r^2$ of 0.847 and SEE of 0.344. The generated models were externally validated using test sets. The final QSAR models as well as the information gathered from 3D contour maps should be useful for the design of novel tetraoxanes having improved antimalarial activity.

붓스트랩을 이용한 다차원척도법의 효율성 연구 (A study on the efficiency of multidimensional scalin using bootstrap method)

  • 김우종;강기훈
    • Journal of the Korean Data and Information Science Society
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    • 제20권2호
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    • pp.301-309
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    • 2009
  • 다차원척도법은 다변량분석에서 개체들을 대상으로 변수들을 측정한 후에 개체들 사이의 비유사성을 측정하고, 그 값들 혹은 반복하여 측정된 경우에는 그 값들의 평균을 이용하여 개체들을 저차원의 공간상에 도시화시켜 표현하는 분석방법이다. 본 논문에서는 응답자의 답변에 기초하여 비유사성을 측정할 때 이상치 또는 응답자의 답변이 불성실할 경우 발생하는 변이문제와 개체들 간의 거리에 대한 통계적 추론 문제에 붓스트랩 방법을 적용하는 내용을 다루고, 활용가능성을 무료일간지에 대한 유사성 평가 자료를 이용하여 실증적으로 분석하였다.

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19세기 초 서양 남성상의 고증제작 연구 (A Study of the Historical Reconstruction of the Western Man's Coat in the Early of the 19th Century)

  • 류경화;김양희
    • 복식
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    • 제65권1호
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    • pp.136-149
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    • 2015
  • This research aimed to study the making of western men's coats in the early 19th century. First of all, the study figured out the concepts and forms of western men's tops in the early 19th century by collecting and categorizing pictures including engravings, paintings and pattern books, and literature data. Second, this research identified the patterns, sewing, and design techniques by examining the pattern books on men's clothing in the early 19th century, and analyzed the preserved costumes to restore the selected models. Third, this research presented historical evidences and patterns after designing a men's tailcoat of the early $19^{th}$ century and checking the fit based on the analyzed forms and design techniques. The research discovered that the analyzed results between the tailcoat forms depicted in literature, pictures and pattern books and preserved costumes were almost identical. From this, it can be assumed that the tailors followed a manual when designing garments during that time given the similarity between historical records and remaining items. In addition, it can be seen that the forms and designing methods of men's clothing in the 19th century were almost similar to that of the modern menswear, despite the differences in producing process.

핫플레이트를 이용한 OLED의 휘도열화특성 분석 (Analysis of Luminance Degradation characteristics of OLED using the Hotplate)

  • 김윤철;이득중;장중순
    • 한국신뢰성학회지:신뢰성응용연구
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    • 제16권4호
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    • pp.356-363
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    • 2016
  • Purpose: The purpose of this study is to propose efficiency of equipment testing the luminance degradation of OLED. Methods: The degradation model of Exponential model and Stretched exponential model is analyzed by goodness of fit test using calculated R-square. The degradation model having the higher R-square is finally selected. Scale parameter and Shape parameter using the selected degradation model is estimated. The activation energy and current density n using peck model among the accelerated model is estimated. the estimated parameters are analyzed by t-test. Results: The results of t-test show that the estimated parameters on chamber and hotplate are equal statistically. we can know the similarity of the luminance degradation rate and degradation pattern on chamber and hotplate. Conclusion: The result of the degradation test on chamber and hotplate is similar. when the accelerated degradation test on the panel of the OLED TV is performed, hotplate is requiring less samples, time and cost than chamber. so the accelerated degradation test on the panel of the OLED TV using the hoplate is efficient of time and cost.

유행관여에 따른 여성기성복 상표이미지 포지셔닝 연구 -20대 직장여성을 중심으로- (A Study on Brand Image Positioning for Ladies' Ready-to wear According to Fashion Involvement - As Object of working women)

  • 박혜원;임숙자
    • 한국의류학회지
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    • 제16권4호
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    • pp.393-403
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    • 1992
  • This Study intended to provide positioning strategies of brand Image for ladies' ready to wear by analysing the perceptual dimensions of working women. The subjects were devided into two groups according to the fashion involvement, and in each group, a positioning map was composed by use of multidimensional scaling. 251 subjects of this study were gathered into stratified sample groups from working women in Seoul, being subdivided according to their each occupation and age. The data were analysed by frequency, percentage, average, $x^{2}-test$, 1-test, Factor Analysis, cronbach's $\alpha$. Also, KYST, PROFIT, PREFMAP for multidimensional scaling were used. The results were as follows. 1. Two groups were identified according to degree of fashion involvement: high-involvement group, and low-involvement group. 2. From the analysis of the similarity of brand image, high involvement group percieved greater difference in brand image than low involvement group. 3. From the analysis of the evaluation of brand attributes, the evaluations in self expression, fashionability, design, sales promotion activity, sociality, quality, fit showed differences bet-ween high involvement group and low involvement group. 4. From the analysis of the preference of brand image, the distribution of preference and ideal point were different between high involvement group and low involvement group.

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매몰재의 혼수비가 치관 보철물 변연의 적합성에 미치는 영향에 관한 연구 (A Study on the Marginal Fit of Dental Prosthesis According to the W/P Ratio of Investment)

  • 황경숙
    • 대한치과기공학회지
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    • 제18권1호
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    • pp.67-72
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    • 1996
  • This test is verifying for influence of W/P ratio of investment upon dental prosthesis Firstly we made 40 MOD die and divide 4 groups, each group take 0.2 different w/p ratio grade such as 0.35, 0.37, 0.39 and 0.41. The method of data analysis applied were by ANOVA, Tukey test and Mann-Whiney and Kruskal Wallis test. The finding of this study were as follows : 1. The 0.37 w/p ratio group showed most accurte margin due to $15.8{\mu}m$ gap between margin and die which keep up with manufacture's instruction and 0.35 w/p ratio group was followed as second accuracy group o 새 $48.3{\mu}m$ gap between margin and die, 0.39 w/p ratio group showed $101{\mu}m$ gap and 0.41 w/p ratio group showed $129.8{\mu}m$ gap. 2. As to the relationship of the margin accuracy between 4 different grade of w/p ratio groups, each group was statistically significant(P<0.01). Also the all groups were statistically significant except between 0.35 and 0.37 groups between 0.39 and 0.41 groups, and between 0.35 and 0.39 groups. 3. A consequence of Mann-Whitney & Kruskal-Wallis test for marginal accuracy between 4 different grade of w/p ratio was statistically significant as same as above ANOVA test result. Also Tukey test for verifying similarity from each group showed same as above.

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