• The Journal of the Society of Korean Medicine Diagnostics
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• v.10 no.1
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• pp.64-77
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• 2006

Objectives Damum is a general and fundamental concept in Oriental me야cine that deals with symptoms of diseases. but as far as Damum is concerned there has not been significant researches in terms of clinical medicine but only researches in the field of medical story. Therefore hopefully this study could contributes to the development of Damum which is very essential concept in Oriental medicine. Methods First of all we have made basic twenty-three items list through conducting researches on documents in regards to Damum, and finally designed twenty-nine survey inquiry by so called Delphi study-method that is based on opinions of professional groups. we have conducted a survey of twenty-nine inquirys on sixty-one cases and asked three Oriental medical doctors who are Damum specialists to diagnose and measure clinical values regarding Damum, followed by studying interrelationship between survey results and clinical values. conclusively we have made out a final Damum questionnaire form by selecting significant question items based on the results of the study. Results According to the analysis of the studies, fourteen question items were selected. Conclusions As far as Damum discriminant is concerned, additional verifing processes are needed to be carried out through more clinical cases. And it is through that more clinical studies are needed to be done in regards to Damum.

• Korean Institute of Interior Design Journal
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• v.23 no.3
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• pp.48-55
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• 2014

Luis Barragan is a representative Mexican architect. He designed architectural space as a local architect in consideration of the Mexico's harsh Mediterranean climate. His manifestation of the regionality can be found mainly in his precise expression of light. Such method and concept of using light in Barragan's architecture made a huge impact on later architects but detailed studies on this issue have not been made actively. Hence, this paper intended to suggest a starting point or an orientation by illustrating the characteristics of using and expressing light in architecture through his cases of housing works. The study method was as follows. First, the general characteristics of light were identified by analyzing the elements of architectural space that dealt with light and the characteristics of expressing light shown in the architectural space. Second, the architectural background of Luis Barragan and the architectural space elements of the light expressed in his architectural space were extracted to form a hypothetical ground. Third, five of his works on the houses in his prime (after the year of 1945) were analyzed to explore the characteristics of relational representation between light and the architectural space elements in his architecture. Through this process, it was learned that, in his architectural works, light was the embodiment of the location-related, time-based, daily and illusionary experience into architecture. In addition, meditative light could be experienced by contrasting the soft and dispersed light and shadow of the inside space of Barragan's houses with the strong external light. Therefore, through the process above, this study is hoped to provide an opportunity for the contemporary architects of our era to rethink the fundamental correlation between architecture and light.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.8 no.1
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• pp.123-132
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• 1997

The purpose of this paper is to introduce the current trends of British Music Therapy and its effectiveness as a therapeutic intervention for the autistic children. This paper consists of two parts；Part one will provide a general picture of music therapy by looking at its fundamental concepts and therories. Part II(two case studies) will illustrate the actual processes of music therapy which can engender a therapeutic relationship between the therapist and the autistic child. Through the first case study of Charlie, a 3 year and 9 month non-verbal autistic boy, we shall see how music therapy facilitates both non-verbal and verbal communication and a form of pretend play. The second case of Mark, a 10 year old autistic boy with complex emotional, behavioural and learning difficulties who had been sexually abused in the past, presents how the therapist’ acceptance of the child’ being and the shared experience of music therapy enable the child to express his difficulties and to develop the awareness of self and others. By exploring both musical and interpersonal aspects of music therapy, this gives an in depth examination of therapeutic processes. In order to clarify clinical procedure, this paper is viewed in musical, developmental and psychodynamic perspectives. To ensure confidentiality, the clients will be referred to by alter-native forenames.

• BMB Reports
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• v.51 no.10
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• pp.481-483
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• 2018

Glioblastoma (GBM) is the most common and aggressive form of human adult brain malignancy. The identification of the cell of origin harboring cancer-driver mutations is the fundamental issue for understanding the nature of GBM and developing the effective therapeutic target. It has been a long-term hypothesis that neural stem cells in the subventricular zone (SVZ) might be the origin-of-cells in human glioblastoma since they are known to have life-long proliferative activity and acquire somatic mutations. However, the cell of origin for GBM remains controversial due to lack of direct evidence thereof in human GBM. Our recent study using various sequencing techniques in triple matched samples such as tumor-free SVZ, tumor, and normal tissues from human patients identified the clonal relationship of driver mutations between GBM and tumor-free SVZ harboring neural stem cells (NSCs). Tumor-free SVZ tissue away from the tumor contained low-level GBM driver mutations (as low as 1% allelic frequency) that were found in the dominant clones in its matching tumors. Moreover, via single-cell sequencing and microdissection, it was discovered that astrocyte-like NSCs accumulating driver mutations evolved into GBM with clonal expansion. Furthermore, mutagenesis of cancer-driving genes of NSCs in mice leads to migration of mutant cells from SVZ to distant brain and development of high-grade glioma through the aberrant growth of oligodendrocyte precursor lineage. Altogether, the present study provides the first direct evidence that NSCs in human SVZ is the cell of origin that develops the driver mutations of GBM.

• Advances in Computational Design
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• v.5 no.4
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• pp.363-380
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• 2020

In this paper, a cylindrical shell is immersed in a non-viscous fluid using first order shell theory of Sander. These equations are partial differential equations which are solved by approximate technique. Robust and efficient techniques are favored to get precise results. Employment of the Rayleigh-Ritz procedure gives birth to the shell frequency equation. Use of acoustic wave equation is done to incorporate the sound pressure produced in a fluid. Hankel's functions of second kind designate the fluid influence. Mathematically the integral form of the Lagrange energy functional is converted into a set of three partial differential equations. Throughout the computation, simply supported edge condition is used. Expressions for modal displacement functions, the three unknown functions are supposed in such way that the axial, circumferential and time variables are separated by the product method. Comparison is made for empty and fluid-filled cylindrical shell with circumferential wave number, length- and height-radius ratios, it is found that the fluid-filled frequencies are lower than that of without fluid. To generate the fundamental natural frequencies and for better accuracy and effectiveness, the computer software MATLAB is used.

• Journal of Ocean Engineering and Technology
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• v.23 no.1
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• pp.74-80
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• 2009

In this study, the static and modal analyses to find the characteristic of eigenvalues for a towed cable were with a free boundary condition at the bottom end carried out with numerical study. The resulting numerical code with finite element method was used to study sample problems for a cable with towing speeds. After tracing the equilibrium state with a towing speed through the static analysis, modal analysis on the basis of static results was performed. The static top tension for a critical towing speed is nearly 50 percent of what it was for a free hanging pipe. From static analyses, it is found that towing speed has a noticeable effect on top tension of a towed pipe. At a high towing speed, differences between the first and second periods become larger. Compared to the fundamental period for a free hanging pipe, that for a towed pipe with a critical towing speed is approximately 1.4 times larger. This result is very important point in that the lock in condition and tension of the towed cable system with top excitation can be predicted. The corrected close form solution to solve natural periods for a towed cable was presented in this study. The code is validated by comparison of the results of theoretical and numerical studies. Two results were in very good agreement. This study can contribute to predicting the lock-in condition and tension for a towed cable or pipe with top excitation.

• IEIE Transactions on Smart Processing and Computing
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• v.5 no.4
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• pp.256-266
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• 2016

Concurrently detected and annotated abnormal events can have a significant impact on surveillance systems. By considering the specific domain of pedestrian trajectories, this paper presents two main contributions. First, as introduced in much of the work on trajectory-based anomaly detection in the literature, only information about pedestrian paths, such as direction and speed, is considered. Differing from previous work, this paper proposes a framework that deals with additional types of trajectory-based anomalies. These abnormal events take places when a person enters prohibited areas. Those restricted regions are constructed by an online learning algorithm that uses surrounding information, including detected pedestrians and background scenes. Second, a simple data-boosting technique is introduced to overcome a lack of training data; such a problem particularly challenges all previous work, owing to the significantly low frequency of abnormal events. This technique only requires normal trajectories and fundamental information about scenes to increase the amount of training data for both normal and abnormal trajectories. With the increased amount of training data, the conventional abnormal trajectory classifier is able to achieve better prediction accuracy without falling into the over-fitting problem caused by complex learning models. Finally, the proposed framework (which annotates tracks that enter prohibited areas) and a conventional abnormal trajectory detector (using the data-boosting technique) are integrated to form a united detector. Such a detector deals with different types of anomalous trajectories in a hierarchical order. The experimental results show that all proposed detectors can effectively detect anomalous trajectories in the test phase.

• Korean Institute of Interior Design Journal
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• v.24 no.2
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• pp.100-107
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• 2015

The paper begins with the idea of the society of the continued rooms that building connects architectural space (building interior) and urban open space (urban interior) or countryside/rural open space (territorial interior). It gives an account of, through literature review, a theoretical possibility of integrating not only architecture and urbanism but also architecture and countryside/rural planning. The first site explores the continuously articulated and connected spaces between building interior, urban interior, and territorial interior, in understanding Alberti's analogy, "A house is a little city." (1452) The second site illustrates architecture as an open boundary and a spatial medium which makes building, urban, and territorial interiors connect and makes them continuous. There is an opportunity of reading the continued relations and the continua of spaces. The third site deals with the form of building that architecture creates for building interior (society of rooms) and urban interior (society of urban rooms), and moderates the interiors. The last site clarifies the territorial interior (society of countryside/rural rooms) that constitutes homogeneous spatiality moderated by architecture between building interior and urban interior. The paper discusses the society of the continued interiors(building/urban/territorial interiors) that ought to be a fundamental truth in the field of every project which deals with a unit of space. It logically clarifies the society of the interiors, not isolated and blocked off but multilayered and continued. It comes to the conclusion that the territorial interior should be subsumed under the design field and the society of the continued rooms ought to be considered as a united object of space in the fields of interior architecture/design, architecture, landscape, urbanism and countryside/rural planning. Ultimately, it aims at offering a departing point of discourse and a theoretical foundation for the future studies on urban interior and territorial interior.

• Earthquakes and Structures
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• v.14 no.2
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• pp.103-115
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• 2018

In this work, a simple but accurate hyperbolic plate theory for the free vibration analysis of functionally graded material (FGM) sandwich plates is developed. The significant feature of this formulation is that, in addition to including the shear deformation effect, it deals with only 3 unknowns as the classical plate theory (CPT), instead of 5 as in the well-known first shear deformation theory (FSDT) and higher-order shear deformation theory (HSDT). A shear correction factor is, therefore, not required. Two common types of FGM sandwich plates are considered, namely, the sandwich with the FGM face sheet and the homogeneous core and the sandwich with the homogeneous face sheet and the FGM core. The equation of motion for the FGM sandwich plates is obtained based on Hamilton's principle. The closed form solutions are obtained by using the Navier technique. The fundamental frequencies are found by solving the eigenvalue problems. Numerical results of the present theory are compared with the CPT, FSDT, order shear deformation theories (HSDTs), and 3D solutions. Verification studies show that the proposed theory is not only accurate and simple in solving the free vibration behaviour of FGM sandwich plates, but also comparable with the higher-order shear deformation theories which contain more number of unknowns.

• Journal of the Korean Society of Costume
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• v.58 no.2
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• pp.93-106
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• 2008

Asia Folk Costumes are certainly different from the Western Costumes. This distinction is based upon the effect of environment, technology, and social structure, and especially, which was generated by religion, ideology, and philosophy. The ideas of fundamental ground of this eastern features are religions such as Buddhism, Taoism, and Confucianism. The religion of the East has determined the form of traditional costumes, affecting the costume up to now. This study aims at the investigation of the effect of religion on the formation of East Asia Traditional Costumes around Korea, China, and Japan and its figurative beauty. Study was carried out by chiefly referring to literatures. Eastern Aesthetics was formed by accepting aesthetic concepts, acquired from the idea of Three Religions. Especially, the ideas of non-duality(不二), emptiness(空), five aggregates(五蘊), mind control(心法), derived by Buddhism, and nature theory(自然論) and creationism(創造論) of Taoism, and abstinence theory(節制論) and decorum(禮法) and the principles of Yin and Yang(陰陽) of confucianism have had great effect on the aesthetics of costume. The figurative features of costume, affected by three religions are described by the factors; First, non structural feature, second, the beauty of abstinence and chastity of ample silhouette, third, the feature of natural color and achromatic color, fourth, the figurative feature of costume by the principles of Yin and Yang, and fifth, bright ornaments. The aesthetic values of the East Asia Costume are 'A Beauty of Vacancy', 'A Beauty of Concealment', 'A Beauty of Nature', and 'A Beauty of Symbolism'. As philosophy, culture, and ethnics itself, the religions of Asia have had effect on the overall culture, which is inclusive of social structure, as well as art and aesthetics, and have decided the style of costume.