• 대한두경부종양학회지
• /
• 제18권1호
• /
• pp.65-70
• /
• 2002

Background and Objectives: Recently the tenn 'papillary microcarcinoma' has been proposed to designate carcinoma of 10 mm or less in diameter. In some cases, cervical lymph node metastasis preceding the occurrence of the primary tumor may be the first and sole manifestation of the disease. The objective of this study is to assess the clinical features of cervical metastasis in papillary microcarcinoma of thyroid glands. Materials and Methods: 9 cases with papillary microcarcinoma with neck metastasis were analyzed retrospectively. 5 cases are men and 4 are women. All patients complained of painless, movable neck mass. The symptom had been present from 1 month to 36 months. We reviewed clinical history, imaging studies, the results of fine needle aspiration, the surgical method, the pathologic results. Results: In 9 cases, no abnormalities of the thyroid gland were shown by imaging studies and thyroid scan. 3 cases were diagnosed by fine needle aspiration cytology. the others were not. Total thyroidectomy and neck dissection were performed in 9 cases and then pathology reports showed 2 case of multiple, 2 case of contralateral single and 5 cases of unilateral single thyroid microcarcinoma. They have no recurrence during follow-up period. Conclusions: Cervical metastasis from papillary microcarcinoma is variable clinical manifestation. The diagnosis of cervical metastasis from papillary microcarcinoma should be considered in patient with neck mass. We recommend total thyroidectomy with neck dissection and postoperative radioactive iodine ablation therapy in neck metastasis from papillary thyroid microcarcinoma.

• 식물병연구
• /
• 제15권1호
• /
• pp.51-53
• /
• 2009

2007년 5월 상순 진주시 초전동 비닐하우스 수박 재배 포장에서 수박 흰비단병이 발생되었다. 병정은 과실 아랫 부분이 수침상으로 물러지고 부패되면서 병반부와 토양 표면에 흰색의 곰팡이가 솜털모양으로 생기고 갈색의 둥근 균핵을 많이 형성하였다. 균핵의 크기는 $1{\sim}3\;mm$이며 균사의 폭은 $4{\sim}8{\mu}m$로서 균사생육과 균핵형성 적온은 $30^{\circ}C$이었다. 균사특유의 clamp connection이 관찰되었다. 수박에서 발생한 병징과 병원균의 균학적 특징 및 병원성을 검정한 결과, 이 병을 Sclerotium rolfsii에 의한 수박 흰비단병으로 명명하고자 제안한다.

• 한국임상약학회지
• /
• 제27권2호
• /
• pp.77-82
• /
• 2017

Background: Clostridium difficile associated diarrhea (CDAD) is a leading cause of hospital-associated gastrointestinal illness. Risk factors for CDAD include advanced age, long-term admission, antibiotics, proton-pump inhibitor or $H_2$ blocker use and immunosuppression. The practice guideline of American Journal of Gastroenterology (2013) suggests metronidazole for the first-line therapy of mild-moderate CDAD as well as vancomycin for severe CDAD. MICU inpatients receiving stress ulcer prophylaxis and antibiotics are susceptible to nosocomial CDAD. Therefore, this study aimed to evaluate occurrence and treatment of CDAD in MICU. Methods: Patients who were admitted to the MICU and had CDAD from August 2012 to August 2015 were analyzed retrospectively. Results: Of the 90 patients with CDAD, 20 patients (2.22%) had mild-moderate CDAD (16 received metronidazole and 4 received vancomycin therapy) and 70 patients (77.8%) had severe CDAD(54 received metronidazole and 16 received vancomycin therapy). Among the patients with mild- moderate CDAD, treatment with metronidazole or vancomycin resulted in same clinical cure in 50% of the patients (p=1.00). Among the patients with severe CDAD, treatment with metronidazole or vancomycin resulted in clinical cure in 40.7% and 50.0% of the patients, respectively (p=0.511). Clinical symptoms recurred in 7.4% of the severe CDAD patients treated with metronidazole and 6.3% of those treated with vancomycin(p=0.875). Conclusion: Our findings suggest that metronidazole and vancomycin are equally effective for the treatment of mild-moderate CDAD; however, vancomycin demonstrated higher clinical cure rate and lower recurrence rate for severe CDAD, although the difference was not statistically significant. For better clinical outcomes, appropriate medication use by disease severity is needed.

• 한국물환경학회지
• /
• 제18권3호
• /
• pp.327-336
• /
• 2002

Disinfection process in water treatment plants (WTPs) is one of the most important step in order to inactivate waterborne disease. However, what is the necessary disinfection in WTPs was not properly established in Korea. This study was conducted to evaluate disinfection performance in nationwide water treatment plants (n=474). Disinfection requirement based on the SWTR (Surface Water Treatment Rule) of the U.S. (1-log Giardia removal) was chosen in estimating the compliance. The scope of unit process for evaluating disinfection performance includes postdisinfection process in clearwells, pipeline, and storage tank. The worst water quality condition in individual WTPs was applied for the disinfection performance evaluation. The major results are as follows. First, it was appeared that 184 WTPs (39 %) provided insufficient disinfection performance. Disinfection performance was significantly improved during past 2 years. The ratio of the number of WTPs providing insufficient disinfection performance in 1999 and 2001 was 78 % and 41 %, respectively. One of major factors for this improvement was due to the improvement of $T_{10}/T$ value in clearwell, as a result of modification of clearwell facility. Second, if disinfection criteria is 3-log Giardia inactivation at worst water quality condition, then 19 % of all WTPs can not meet this disinfection criteria. And if disinfection criteria is strengthened to 4-log Giardia inactivation, then 58 % of all WTPs can not meet this disinfection criteria. Since disinfection criteria is decided by contamination level of Giardia in source water, it also needs the investigation of Giardia occurrence in source water.

• Weed & Turfgrass Science
• /
• 제2권3호
• /
• pp.306-311
• /
• 2013

Pythium aphanidermatum에 의한 잎마름병(pythium blights)이 chewing fescue "Jamestowm II" 품종에서 2011년 6월 상순에 대구대학교 시험포장에서 발생하였다. 잔디에 발병증상은 잎 끝으로부터 잎마름 증상과 뿌리 썩음증상이 나타나고, 잎색은 진한갈색,회 갈색으로 나타났다. 병원균은 병든 잎과 지제부에서 분리를 하였으며, 동정을 위하여 PDA에서 배양하였다. 균사에는 잎 같은 포자가 복잡한 구조로 부풀어져 있고, 균사로부터 구별되지 않은 실같은 포자낭이 있다. 리보소옴 DNA의 염기서열을 분석한 결과, 유전자은행 DB에 P. aphanidermatum 균주 와의 100% 상동성을 나타낸다는 것을 확인하였다. 병원성은 chewing fescue, creeping bentgrass 및 Kentucky bluegrass에서 코흐의 원칙에 따라 확인하였다. 이것은 chewing fescue 종에서 P. aphanidermatum 에 의한 잎마름병을 국내에서 처음보고 한다.

• 한국식물병리학회지
• /
• 제14권5호
• /
• pp.445-451
• /
• 1998

A severe Phytophthora rot of strawberry caused by a species of Phytophthora has been widely occurred at major cultivation areas of Kimhae on August in 1997. Incidence of the disease was obtained in the range of 69.2~83.6% in surveyed 4 fields and showed an average of 75.2%. A species of Phytophthora was mostly isolated from the crown of infected strawberry plants and all the isolates were identified as P. nicotianae var. nicotianae (=P. parasitica). The fungus showed strong pathogenicity on strawberry by inoculation test. As a result of the leaf inoculation using mycelial disks of the fungus, both leaves and petioles were darkly browned, and were finally blighted. As a result of the root inoculation of zoospore suspension, both roots and crowns were rotten with dark brown. Although the fungus produced sporangia either on V-8 juice agar medium or liquid medium, the sporangia observed on the liquid medium appeared to be broadly turbinate and noncaducous. Moreover the fungus cultured on the liquid medium often produced sporangia having two papilla. The number of zoospores in sporangia was found to be ranged from 3 or 4 to as many as 20 or 25. In addition, the released zoospore from the sporangium became the cystospore during the prolonged culture of the fungus. The sporangia were measured as av. 49$\times$35 ${\mu}{\textrm}{m}$ with l/b ratio of 1.43. All isolates from crowns were heterothallic and A1 mating type since oospores were abundantly formed on clarified V-8 juice agar by dual culture with P. capsici A2 mating type. Aplerotic oospores were sized 24-26 ${\mu}{\textrm}{m}$. Antheridia were always amphigynous and recoreded an average of 12$\times$10 ${\mu}{\textrm}{m}$. Hyphal swlling were easily observed, and terminal or intercalary chlamydospores were abundantly formed on V-8 juice agar as well as in C/Z solution and sized av. 28.2 ${\mu}{\textrm}{m}$. This is the first report of Phytophthora rot of strawberry in Korea.

• 대한족부족관절학회지
• /
• 제23권4호
• /
• pp.183-188
• /
• 2019

Purpose: Bone contusion is usually treated with conservative therapy for 3 months. Bone contusion around knee and hip joints has been extensively reported on, but there are scant reports on this condition in foot and ankle joints. This study evaluated the nature, characteristics and location of bone contusion around foot and ankle joints to enlighten clinicians on how to better treat this disease entity. Materials and Methods: We classified bone contusion of the 76 patients into three types (102 sites; 47 ankle sprains, 18 traffic accidents, 11 falls) according to the Costa-Paz system with employing magnetic resonance imaging (MRI), and the study then analyzed the common sites and areas of occurrence according to the mechanism of injury and duration of pain after first conducting conservative therapy. Results: Of the 76 patients (102 sites) on the MRI, 43 case (42.2%) for talus, 19 cases for distal tibia, and 12 cases for calcaneus were involved. The classification, according to the Costa-Paz system, was Type I, 51 cases; Type II, 32 cases; and Type III, 19 cases. The duration of pain after conservative treatment was 12.15±2.17 weeks for Type I, 14.5±2.15 weeks for Type II, and 21.0±3.8 weeks for Type III. Conclusion: The most common location of post-traumatic bone contusion around both the foot and ankle is the talus, distal tibia, and calcaneus. The most common type of injury noted on MRI is a diffuse signal with change of the medullary component (Type I), In cases of bone contusion extending to a subjacent articular surface or disruption or depression of the normal contour of the cortical surface (Types II, III), the patients' pain appears to last longer. Thus, it is necessary to consider a longer period of conservative treatment in cases of Types II and III bone contusion because the patients' pain may last longer than 3 months.

• 한국균학회지
• /
• 제34권2호
• /
• pp.122-124
• /
• 2006

2005년 3월경 경남농업기술원 움막저장고에서 저장중이던 초석잠의 덩이줄기에 이상증상이 발생하였다. 병징은 초석잠 덩이줄기 부분이 수침상으로 물러지고 썩으면서 병반부위에 회색의 곰팡이가 많이 생겼다. 분생포자는 무색, 단포자이며 난형 또는 타원형으로 크기는 $5{\sim}16{\times}4{\sim}12{\mu}m$였다. 분생포자경은 갈색으로 격막이 있고 나무가지 모양이며, 폭은 $14{\sim}30{\mu}m$였다. 균사생육과 균핵형성 적온은 $20^{\circ}C$였다. 초석잠에서 병징과 병원균의 균학적 특징, 병원성을 조사한 결과 Botrytis cinerea Persoon:Fries에 의한 초석잠 잿빛곰팡이병으로 동정하였다.

• 한국균학회지
• /
• 제46권2호
• /
• pp.200-204
• /
• 2018

2016년 4월에 한국 구례지역에서 재배하는 쑥부쟁이 줄기에 균핵병이 발생하였다. 그 병징은 주로 줄기에 발생하여 물러 썩어서 심하면 식물체가 마른다. 흰색 균사가 감염된 식물체 줄기와 땅 표면에 퍼져있으며, 병든 줄기 내와 병 발생 부위에 작은 흑색 균핵을 형성하였다. 균핵병은 쑥부쟁이 재배 포장에서 20~80% 높게 발생하였다. 분리균의 형태적 특성 및 유전자 분석에 의하여 이 균은 Sclerotinia minor로 동정하였다. 한국에서 쑥부쟁이에서 분리한 Sclerotinia minor에 의한 균핵병 발생을 처음으로 보고한다.

• 식물병연구
• /
• 제18권1호
• /
• pp.45-48
• /
• 2012

저온다습한 날씨가 지속된 후의 2011년 8월 초순에 경기도 동두천시 소요산에서 겹둥근무늬와 조기낙엽 증상을 나타내는 네군도단풍이 발견되었다. 병든 잎의 뒷면에서 원뿔 모양이며 흰색의 분생포자가 다수 관찰되었다. 현미경 검경을 통하여 형태적 특징을 검토한 결과, 이 증상의 원인균은 Cristulariella moricola로 동정되었다. 상대습도 100% 및 $18{\pm}2^{\circ}C$의 조건에서 인공접종을 통하여 이균의 병원성을 증명하였다. 한편, 분리 균주의 internal transcribed spacer 영역의 염기서열을 분석하고 NCBI에 등록된 균의 염기서열과 비교함으로써 이 균이 C. moricola임을 증명하였다. 네군도단풍에 C. moricola의 감염에 의해 발생한 둥근무늬낙엽병은 우리나라에서 최초의 기록이다.