• Composites Research
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• 제15권4호
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• pp.23-31
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• 2002

시편 게이지 면적($길이{\;}{\times}{\;}폭$)의 이차원 크기효과가 T300/924 $[45/-45/0/90]_3s$ 탄소섬유/에폭시 적층판의 압축거동에 대해 조사하였다. 개조된 압축시험치구(ICSTM)와 좌굴방지장치가 $30mm{\;}{\times}{\;}30mm,{\;}50mm{\;}{\times}{\;}50mm,{\;}70mm{\;}{\times}{\;}70mm,{\;}90mm{\;}{\times}{\;}90mm$의 게이지 길이와 폭을 가진 시편들의 압축시험에 사용하였다. 모든 경우의 파괴들은 시편 게이지 길이 내에서 주로 갑자기 발생하였다. 파괴 후 분석결과는 $0^{\circ}$층의 섬유의 미소좌굴에 의해 파괴를 시작하여 최종파괴를 일으키는 임계파괴기구일 것으로 생각되었다. 이것은 매트릭스 지배적인 파괴를 의미하며, 초기섬유굴곡에 따라 파괴가 지배적으로 시작된다는 것을 말한다 이것은 또한 제작공정과 품질이 압축강도를 결정하는 중요한 역할을 한다고 볼 수 있다. 좌굴방지장치를 장착하고 시험할 때 장치의 볼트 조임 토크에 따라 시편과의 접촉마찰 등에 의해 실제 압축강도 보다 크게 나타나는 결과를 보였다. 좌굴방지장치의 영향을 유한요소법을 이용하여 해석한 결과 실제 압축강도 보다 7% 정도 크게 나타남을 확인하였다. 부가적으로 홀을 갖는 시편들의 압축시험도 수행되었다. 홀에 의한 국부응력집중이 적층판 강도에 지배적 요인이었다. 파괴강도는 홀 크기와 시편 폭이 증가할수록 감소하였으나 탄성응력집중계수로 예측된 값보다는 일반적으로 크게 나타났다. 이것은 사용된 복합재가 이상적인 취성재질이 아니라는 것을 의미하며 홀 주위에서 다소간의 응력이완이 발생한다고 볼 수 있다. X선 검사 사진분석에서 섬유좌굴과 층간분리형태의 손상이 파괴하중의 약 80%에서 홀 가장자리로부터 시작되었고 임계파괴크랙길이인 2-3mm의 불안정한 상태에 도달하기 전까지는 하중 증가와 더불어 안정되게 파괴가 진전되었다(시편의 기하학적 크기에 의존함). 이 손상과 파괴는 선형 cohesive zone 모델로 해석되었다. 노치없는 시편의 압축강도와 평면 파괴인성의 측정된 적층판 변수들을 사용하여 홀의 크기와 시편 폭의 함수로서 홀을 갖는 적층판의 압축강도를 성공적으로 예측하였다.

• 대한치과보철학회지
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• 제48권2호
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• pp.111-121
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• 2010

연구목적: 본 연구에서는 임플란트 주변 골흡수 양상의 차이가 임플란트와 주변골의 응력 분산에 미치는 영향을 알아보기 위해 수평 골흡수와 임플란트 주변 수직 골흡수에 있어서 주변골의 응력분산, 생물학적 폭경의 형성과 응력분산의 변화 관계 및 병적인 골흡수시의 주변골 응력분포를 유한요소 분석법을 사용하여 비교하고자 하였다. 연구 재료 및 방법:우측 제1 소구치 전방에서 제2 대구치 후방까지의 하악골 모형에서 자연치를 제거하고 직경 4.0 mm, 길이 10.0 mm의 나사형 임플란트를 제1 대구치 부위에 식립하였다. 수평 수직 골흡수의 차이를 보기 위하여 골흡수가 나타나지 않은 형태를 대조군 (I)으로 하여, 1.5 mm 수평 골흡수 (H1.5), 3.0 mm 수평 골흡수 (H3.0) 모형과 이에 상응하는 수직 골흡수 모형 (VW1.5; 1.5 mm, VW3.0; 3.0 mm)을 설계하였고, 생물학적 폭경의 형성과 응력 변화를 관찰하기 위해 생물학적 폭경이 형성되는 과정을 가정한 모형(B0; 피질골에서 임플란트와의 골유착이 없이 밀접하게 접촉된 상태, B1; 피질골에 0.5 mm 폭의 수직 골흡수가 발생한 상태)과 생물학적 폭경이 형성된 상태 (B2)의 모형을 설계하였으며, 생물학적 폭경이 형성된 상태는 0.5 mm 폭을 가지며 임플란트 장축에 경사진 형태를 가지고 있는 1.5 mm 깊이의 수직 골흡수 상태로 형성하였다. 병적 골흡수 상태는 수직 골흡수를 가정한 기존 모형 (VW1.5, VW3.0)과 골흡수가 더 진행된 VW4.5, 기저부에 피질골화가 이루어지지 못한 VO3.0, VO4.5, VO6.0모형을 추가하였다. 하중조건은 수직, 수평하중 그리고 협측 $45^{\circ}$경사하중을 각각 100 N씩 임플란트 보철물 부위에 가하였다. 결과: 분석결과 수평 골흡수와 수직 골흡수에 있어서 전반적인 응력의 크기와 임플란트에 가해지는 응력의 크기는 서로 대응하는 모형에서 유사하였으며, 수직 골흡수에 서 수직력을 받을 때 C2에서 C4로 1.5 mm의 골흡수가 증가하였으나 골에서 발생한 최대응력은 오히려 감소하였다. 수직 골흡수에서 응력이 결손부의 수직 벽을 통해 상부로 분산되는 것을 볼 수 있었다. 생물학적 폭경 형성 단계에서 응력이 가해지는 경우 피질골에서의 결합이 없는 A2에서 피질골 전반에 높은 응력이 발생하였으며 생물학적 폭경의 완성을 가정한 B1에서는 임플란트와 피질골의 경계에서 발생한 응력이 경사진 피질골을 따라서 퍼져나가고 있음을 보였다. 병적 골흡수에서 골결손부 하방에 피질골이 없는 경우는 골흡수에 비례하여 응력이 증가 하였으나 피질골이 있는 경우에는 응력의 증가가 골흡수량의 증가와 비례하지 않음을 보였다. 결론: 임플란트 주변 골흡수의 양이 같아도 흡수된 형태에 따라 발생하는 응력의 크기와 응력분산이 다르게 나타났으며 초기 골흡수 현상은 피질골과의 결합이 약할 때 이 부위에 응력이 증가되어 나타나며, 이후 응력이 감소되어 평형을 이루는 것으로 보인다. 수직 골흡수가 증가할 경우 피질골의 존재 유무가 응력 분산에 큰 영향을 미치며 피질골이 있는 경우 일정 범위에서 응력의 감소가 나타나 응력분산에 유리한 형태에서 골흡수의 진행을 감소시킬 수 있을 것으로 보인다.

• 콘크리트학회논문집
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• 제24권3호
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• pp.293-303
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• 2012

최근 건설기술의 발전에 따라 구조물이 대형화, 고층화, 장대화되고 있으며, 동시에 다양한 기능을 수행하고 있다. 그러나 요즘 들어 그 빈도수가 증가하고 있는 충돌 사고나 테러에 의한 폭발, 화재 등에 의한 극한하중이 상기의 구조물에 작용할 경우, 구조물의 손상뿐만 아니라 인명과 재산의 피해 정도가 상당히 커질 수 있다. 특히, 충격이나 폭발하중은 구조물에 작용하는 압력 또는 하중이 매우 짧은 시간에 발생하게 되고, 이러한 하중을 받는 구조물은 준-정적(quasi-static) 하중을 받는 구조물과는 다른 응답을 나타내게 되며 반드시 변형률 속도와 손상 효과를 고려해서 설계가 이루어져야 한다. 그러므로 이 연구에서는 콘크리트 슬래브의 충격저항성능 향상을 위해서 강섬유를 전체 부피의 0%에서 1.5%까지 혼입하고, 두 가지 종류의 FRP 시트를 인장부에 보강하여 저속 충격하중에서의 휨 실험을 수행하였다. 실험 결과 FRP 시트를 인장부에 보강할 경우에 최대 충격하중 및 소산에너지, 파괴 시의 타격 횟수가 증가하였으며, 최대 처짐 및 회전각은 감소하여 충격저항성능이 크게 향상되는 것으로 나타났다. 이러한 결과는 추후 극한하중에 노출될 수 있는 주요 시설물의 설계 시 유용하게 사용될 수 있을 것으로 판단된다. 또한, 이 논문에서는 두 가지 종류의 FRP 시트로 보강된 강섬유 보강 콘크리트 슬래브의 저속 충격하중에서의 동적응답을 해석하기 위하여 외연적 시간적분에 기초한 유한요소해석 프로그램인 LS-DYNA를 사용하였으며, 해석 결과 오차율 5% 이내로 비교적 정확하게 최대 처짐을 예측하는 것으로 나타났다.

• 전산구조공학
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• 제7권3호
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• pp.95-103
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• 1994

원자력발전소 부품중 안전과 관련된 구조물은 지진하중하에서 그 건전성을 유지하도록 설계되어야 한다. 그중 원자로내부구조물부품은 1차 내진분류에 속하는 것으로써 지진하중하에서의 건전성이 발전소 안전과 경제적인 관점에서 매우 중요하다. 지금까지 이러한 원자로내부구조물의 모델링에 대해서는 여러 사람들에 의해 연구되고 발표되었으나, 본 논문에서는 국내 발전소 중에서 Turn-jey base로 건설되어 이미 가동 중에 있는 영광 1&2호기의 원자로내부구조물에 대한 안전정지지진하의 거동을 Global Beam Model이라는 단순화된 모델을 이용하여 분석하였다. 이 모델의 설정을 위해서 주요부품들을 double pendulum의 보요소로 표현하였고, 이들 주요부품들의 특성해석을 범용유한 요소해석 코드인 ANSYS에 의해 구하여 이를 상부 및 하부에서 간격을 갖는 비선형 스프링으로 모델링하였다. 또한 이 비선형 스프링뿐만아니라 원자로용기와 원자로내부구조물부품들 사이의 유체동적현상을 묘사한 유체동력학적 coupling에 의해 pendulum의 보요소를 서로 연결시켜 모델링을 하였다. 가진자료인 안전정지하중은 영광 1&2호기의 원자로용기 지지부에 가해지는 응답스펙트럼을 시간이력함수로 바꾸었으며, 이 모델과 간진 하중을 가지고 비선형해석 code인 KWUSTOSS의 explicit Runge-Kutta-Gills algorithm을 이용하여 적분을 수행하므로써 안전정지지진하의 원자로 내부구조물에 대한 거동을 구하여 이 구조물의 주요부품에 대한 내진검증 및 구조물 내부에 있는 핵연료집합체의 내진 해석을 위한 입력자료를 확보할 수 있었다. 그리고 본 연구에서 사용된 Globa Beam Model의 간편성 및 효율성과 explicit Runge-Kutta-Gills algorithm에 대한 경제성을 확인할 수 있었다.파악되었 다. 그 외에도 '옥외공간이용 편리'(outdoor or recreation convenience)와 ' 이웃만족'(satisfaction with neighbors), 그리고 '주거환경 유형'(building type, building arrangement type)등도 유의한 인과적 관련을 보이므로써, 기존 문헌들이 제시하고 있는 것보다 훨씬 다양한 변수들이 다양한 경로를 통해 거주자 시각만족의 영향인자가 될 수 있는 가능성을 제시하고 있다. 가설 변수의 하나인 '길찾기의 난이 정도'(difficulty of way-finding)와 종 속변수간에 유의한 관련도가 나타나지 않은 이유로 길찾기 변수가 '시각만 족'보다는 거주자의 '안전만족'(safety)과 관련된 변수일 가능성도 아울러 지적되었다. 본 연구의 결과로부터, 주거 계획 및 설계분야 그리고 추후 관 련 연구 분야를 위한 여러 제안들이 제시되었다.에 관한 국가 규격은 국제 규격에서 저술한 바와 같이 특별히 규정된 것이 없고 VDE(Verband Deutscher Elektrotechniker: 서독전기기술 협회)와 SAE(Society of Automotive Engi- neers: 자동차 기술자 협회)에서 비교적 활발하고 Jaso(Japanese Automobile Standards Organization: 일본 자동차 표준협회)에서 많이 진행중에 있다. 본 고에서는 자동차의 전자제어에 따른 잡음 발생 요인과 전자파 간섭 관련 자동차 규격과 시험평가 방법에 대해 간단히 소개 하였다.저하에 저해요인으로서가 아니라, 인위적이던 자연적이던 간에 아들만 두면 단산하는 현행의 출산풍토하에서는 남아선호관이 오히려 출산력저하에 결정적으로 작용하고 있다고 하겠다. 태아의 성 판별을 통한 선택적 인공임신중절의 건수는 1990년 한해에

• 한국지반공학회논문집
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• 제23권9호
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• pp.5-16
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• 2007

비배수 상태에서의 변수 $S_u,\;E_u$, n의 함수로 표현되는 단순한 선형 완전점탄성 모델은 굴착 중에 연성 토양에 시공되는 지중연속벽의 변위를 예측하는데 사용된다. 그러나 유한요소해석에서의 이러한 모델은 굴착이 잠시 중단되었거나 완료된 후 지중연속벽의 측방향 변위를 연속적으로 예측하는 데 한계가 있다. 굴착이 이루어지지 않는 동안의 지중연속벽 주변 토양의 변형 거동특성을 연구하기 위하여, 지중연속벽 주변 토양에 작용하는 응력상태를 가정한 '방콕 연약 점토'에 대한 일련의 삼축압축시험이 모사되었다. 본 연구에서는 세 가지 다른 조건에서의 삼축압축시험이 실시되었는바, 압밀 비배수 조건에서의 재하($CK_0UC$), 압밀 배수 및 비배수 조건에서의 재하 및 제하($CK_0DUC$와 $CK_0UUC$)의 조건에서 시험이 실시되었다. 시험으로부터 일련의 $CK_0DUC$ 시험에서 얻은 전단강도는 $CK_0UC$ 시험에서의 잔류강도와 같음을 알 수 있었다. $CK_0DUC$ 시험에서 시험편에 가해지는 수평압력을 점진적으로 감소시키면서 측정한 탄성계수는 편차응력의 증가와 더불어 감소함을 알 수 있었다. 또한 $CK_0UC$와 $CK_0DUC$시험에서 한계상태 관계의 기울기가 동일하게 나타났다. 더욱이, $CK_0DUC$시험에서 수평압력을 점진적으로 감소시킬 경우의, 축방향 및 반경방향 변형율 증가율을 시간, 한계상태 관계의 기울기, 편차응력과 평균 유호응력의 비의 함수로 표현할 수 있었다. 이 연구는 삼축압축시험의 제하 과정에서 얻은 시험 결과가 굴착 중 지중연속벽의 변형을 예측하는데 사용될 수 있음을 보였다.AFM)과 Scanning Electron Microscopy(SEM)을 통해 관찰한 GST 다층박막시료의 고온 열처리 전후 표면미시거칠기 변화도 PRAM 기록기를 사용할 때에는 in-situ 타원계를 사용할 때보다 1/10 정도의 크기를 보여주어 PRAM 기록기와 분광타원계를 사용하여 결정한 GST의 고온광학물성의 신뢰성을 확인하여 주었다.>, 여자 $179.1{\pm}37.2%$이었다. 평균필요량에 비해 가장 낮은 양을 섭취한 영양소는 엽산으로서 남자 $60.1{\pm}10.8%$, 여자 $54.6{\pm}9.9%$로 조사되었다. 칼슘의 섭취량은 평균필요량에 비해 전체 $74.9{\pm}31.9%$로 나타났다. 에너지 섭취량에 있어서 남자 노인들은 모두가 필요추정량의 75% 미만을 섭취하고 있었고 여자 노인의 경우에도 97%가 필요추정량의 75% 미만을 섭취하여 에너지 섭취량이 매우 낮았다 반면에 단백질 섭취량에 있어서는 남자 노인의 경우 100%가 평균필요량의 125%를 초과하였고, 여자 노인의 경우에는 91%가 평균필요량의 125%를 초과하여 대조적이었다. 비타민 A와 E는 각각 평균필요량과 충분섭취량의 125%를 초과하는 비율이 높게 나타난 반면에 비타민 $B_2$는 특히 남자 노인에서 평균필요량의 75%미만을 섭취한 비율이 높게 나타났다. 엽산 섭취량에 있어서는 평균필요량의 75% 미만을 섭취한 비율이 전체 96%로 나타나 심각한 부족상태로 조사되었다 반면에 철의 섭취량은 남녀 모두 100%가 평균필요량의 125%를 초과하여 섭취한 것으로 나타났다. 아연의 섭취량은 남자 17%,여자 15%가 평균필요량의 75% 미만을 섭취한 것으로 조사되었다. 에너지와 엽산은 모든 노인들에서 평균필요량에 미달되게 섭취한

• 한국구조물진단유지관리공학회 논문집
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• 제27권6호
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• pp.152-161
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• 2023

일반적으로 대용량의 수소를 저장하기 위해 사용되는 수직형 원통 용기는 강재로 제작되며, 사용 환경을 고려하여 제작된 받침 콘크리트 상부에 기초 슬래브에 선 설치된 앵커로 고정하는 방식이 사용된다. 이와 같은 방식은 지진과 같은 외력이 작용될 시 정착부에 응력이 집중될 수 있으며, 앵커 및 콘크리트 손상으로 인한 구조물의 전도 피해가 발생할 수 있다. 본 연구는 현장 조사를 통한 실제 운용중인 수직형 수소 저장용기를 특정하여 3차원 유한요소로 모델링하였고, 비 구조 요소의 내진 성능 검토에 사용되는 ICC - ES AC 156의 인공 지진 및 규모 5.0 이상의 국내 기록지진을 적용하여 거동 특성을 분석하였다. 실제 규모로 제작된 구조물을 대상으로 실험을 진행하는 것이 타당하지만 현실적 제약으로 수행하기에 어려움이 있어 해석적 접근 방식을 통하여 대상 구조물의 안전성을 검토하였다. 거동 특성의 경우 지진동에 의해 발생된 구조물의 응답 가속도는 검토되는 지진 하중 대비 평균적으로 10 배 이상 크게 증폭이 되는 것으로 나타났으며, 무게 중심이 위치되는 지점으로 전달될수록 감소되는 경향을 보였다. 취약 부위로 예상되는 하부 시스템(지지 기둥 및 앵커 정착부)의 경우 허용 응력을 만족하는 것으로 나타났지만, 정착을 위한 받침 콘크리트의 쪼갬 및 인장 강도는 허용 응력 대비 약 5 % 정도의 여유만이 있어 이에 대한 대처 방안이 요구된다. 본 논문에서 제시된 연구 결과를 바탕으로 향후 진동대 시험을 통하여 수행이 되는 수소저장 용기 제작에 필요한 설계 하중 및 조건 등의 기초자료로 활용될 수 있을 것으로 사료된다.

• 한국지반공학회논문집
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• 제35권5호
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• pp.5-19
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• 2019

암반으로 구성되어 있는 급경사($65^{\circ}{\sim}85^{\circ}$)비탈면이 장기간 안정한 상태로 유지되고 있는 자연현상을 고려할 때, 설계 및 초기 시공 단계에서 위와 유사한 지반 상태로 이루어진 깎기 암반비탈면에 대해 1:0.5(발파암 경사 기준)보다 급한 경사를 적용할 수 있을 것이다. 급경사로 설계 가능한 양호한 연속체 암반비탈면의 안정성을 검토하는 과정에서, 설계실무 측면에서 범용적인 암반강도정수 산정방법이 필요하게 되었다. Hoek 등(2002)이 수정 보완하여 발표한 Hoek-Brown 파괴기준과 GSI분류는 불연속구조의 영향을 충분히 고려한 암반특성화 시스템으로 평가되었으며, 응력변화에 따라 등가 Mohr-Coulomb 강도정수(등면적법)를 산출하는 방법을 제안하였다. 비탈면에서는 등가 M-C 강도정수가 최대구속응력(${{\sigma}^{\prime}}_{3max}$ 또는 수직응력)변화에 따라 민감하게 변화하므로 실무적으로 활용하기에 어려운 점이 있다. 이 연구에서는 양호한 연속체 암반비탈면에 대해 최대구속응력 범위이내에서 범용적으로 적용할 수 있는 강도정수산정방법(등각분할법)을 H-B 파괴기준을 응용하여 제안한다. 등각분할법 강도정수(A)의 타당성 및 적용성을 평가하기 위해, 연구대상 암반비탈면을 기존 실시설계 현장 인근에 있는 급경사 비탈면에서 암석종류별(화성암, 변성암, 퇴적암)로 선정하고, Hoek이 제시한 등가 M-C 강도정수(등면적법)들과 비교 분석하였다. 등면적법 및 등각분할법 등가 M-C 강도정수는 기본적인 자료인 기존 실시설계 현장의 실내 암석 삼축압축시험과 연구대상 암반비탈면의 불연속구조의 특성조사(Face Mapping)를 통해 RocLab 프로그램(H-B 파괴기준을 기본으로 전산화된 지반정수 산정 소프트웨어)을 활용하여 산정하였다. 산정된 등면적법 등가 M-C 강도정수는 상호 연동되어 점착력과 내부마찰각이 아주 크거나($45^{\circ}$ 이상) 작게 나타났다. 등각분할법 등가 M-C 강도정수는 등면적법 등가 M-C 강도정수의 중간 정도이며, 내부마찰각은 $30^{\circ}{\sim}42^{\circ}$의 범위를 보인다. 연구대상 암반비탈면의 등각분할법 강도정수(A)와 기존 실시 설계 현장에서 연구대상 암반비탈면과 유사한 암반상태(동일 등급 RMR)에 적용한 강도정수(B)와 비교 분석하고, 이 지반정수들로 적용한 비탈면 안정해석(한계평형해석과 유한요소해석) 결과를 통해 제안한 등각분할법의 적용성을 간접적으로 평가하였다. A와 B의 강도정수 차이는 10% 정도이다. 한계평형해석 결과(우기 기준), A적용 안전율(Fs)=14.08~58.22(평균 32.9), B적용 안전율(Fs)=18.39~60.04(평균 32.2)이며, 각 동일한 암석종류에 따라 상호 유사하게 나타났다. 유한요소 해석 결과, A적용 변위=0.13~0.65mm(평균 0.27mm), B적용 변위=0.14~1.07mm(평균 0.37mm)으로 매우 유사하다. H-B 파괴기준을 응용하여 등각분할법으로 산출한 지반 정수를 실무적인 전단강도로 적용할 수 있는 적용성 평가에서 유의미한 결과를 확인할 수 있었다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
• /
• pp.17-17
• /
• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.