• Title/Summary/Keyword: fine count

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Metastatic lipid-rich mammary carcinoma in a dog

  • Kim, Myung-Chul;Kim, So-Yeon;Lee, Su-Hyung;Kim, Dae-Yong;Yoon, Jung-Hee;Kim, Wan Hee;Lee, Jeong-Ha;Kim, Yongbaek
    • Korean Journal of Veterinary Research
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    • v.54 no.4
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    • pp.265-268
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    • 2014
  • An adult female dog was presented for evaluation of mammary gland masses. Complete blood count and serum chemistry data were within normal limits. Fine-needle aspiration cytology of the mammary masses revealed clusters of malignant epithelial cells with clear cytoplasmic vacuoles. Based on histopathological findings, a diagnosis of lipid-rich mammary carcinoma was made. Approximately 5 weeks after surgical removal, the tumor recurred at the surgery site and metastasis to the tibia was detected. Due to the poor prognosis and deterioration of the condition, the dog was euthanized.

270 MHz Full HD H.264/AVC High Profile Encoder with Shared Multibank Memory-Based Fast Motion Estimation

  • Lee, Suk-Ho;Park, Seong-Mo;Park, Jong-Won
    • ETRI Journal
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    • v.31 no.6
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    • pp.784-794
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    • 2009
  • We present a full HD (1080p) H.264/AVC High Profile hardware encoder based on fast motion estimation (ME). Most processing cycles are occupied with ME and use external memory access to fetch samples, which degrades the performance of the encoder. A novel approach to fast ME which uses shared multibank memory can solve these problems. The proposed pixel subsampling ME algorithm is suitable for fast motion vector searches for high-quality resolution images. The proposed algorithm achieves an 87.5% reduction of computational complexity compared with the full search algorithm in the JM reference software, while sustaining the video quality without any conspicuous PSNR loss. The usage amount of shared multibank memory between the coarse ME and fine ME blocks is 93.6%, which saves external memory access cycles and speeds up ME. It is feasible to perform the algorithm at a 270 MHz clock speed for 30 frame/s real-time full HD encoding. Its total gate count is 872k, and internal SRAM size is 41.8 kB.

Peripheral Blood Lymphocytosis without Bone Marrow Infiltration in a Dog with T-Zone Lymphoma

  • YeSeul Jeon;Hyeona Bae;DoHyeon Yu
    • Journal of Veterinary Clinics
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    • v.40 no.3
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    • pp.203-208
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    • 2023
  • A 13-year-old neutered male mixed-breed dog presented with generalized lymphadenopathy and erythematous cutaneous lesions in the ear pinnae. Fine-needle aspiration cytology of the lymph nodes revealed small to intermediate lymphocytes with a "hand mirror" configuration as the predominant cell type. Histopathological analysis of the lymph node showed an infiltrate of CD3-positive small lymphocytes compressing the follicles against the capsule owing to neoplastic cell expansion. Flow cytometric analysis revealed a homogeneous population of CD3+/CD4-/CD5+/CD8-/CD21+/CD34-/CD45- cells in both the peripheral blood and aspirated lymph nodes, which supports the diagnosis of T-zone lymphoma. Laboratory tests revealed lymphocytosis (14,144 cells/µL) in the peripheral blood. However, contrary to expectations, the bone marrow examination revealed no evidence of lymphocytic infiltration. T-zone lymphoma is an indolent lymphoma with a long survival period, and knowledge of its characteristics may affect disease staging and prognosis evaluation. Therefore, peripheral blood count as a sole screening tool for bone marrow metastasis should be used with caution.

Improved fast neutron detection using CNN-based pulse shape discrimination

  • Seonkwang Yoon;Chaehun Lee;Hee Seo;Ho-Dong Kim
    • Nuclear Engineering and Technology
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    • v.55 no.11
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    • pp.3925-3934
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    • 2023
  • The importance of fast neutron detection for nuclear safeguards purposes has increased due to its potential advantages such as reasonable cost and higher precision for larger sample masses of nuclear materials. Pulse-shape discrimination (PSD) is inevitably used to discriminate neutron- and gamma-ray- induced signals from organic scintillators of very high gamma sensitivity. The light output (LO) threshold corresponding to several MeV of recoiled proton energy could be necessary to achieve fine PSD performance. However, this leads to neutron count losses and possible distortion of results obtained by neutron multiplicity counting (NMC)-based nuclear material accountancy (NMA). Moreover, conventional PSD techniques are not effective for counting of neutrons in a high-gamma-ray environment, even under a sufficiently high LO threshold. In the present work, PSD performance (figure-of-merit, FOM) according to LO bands was confirmed using a conventional charge comparison method (CCM) and compared with results obtained by convolution neural network (CNN)-based PSD algorithms. Also, it was attempted, for the first time ever, to reject fake neutron signals from distorted PSD regions where neutron-induced signals are normally detected. The overall results indicated that higher neutron detection efficiency with better accuracy could be achieved via CNN-based PSD algorithms.

Liquefaction Evaluation of Reclaimed Sites using an Effective Stress Analysis and an Equivalent Linear Analysis (유효응력해석과 등가선형해석을 이용한 매립지반의 액상화 평가)

  • Park, Sung-Sik
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.28 no.2C
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    • pp.83-94
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    • 2008
  • In this study an effective stress analysis was performed to evaluate liquefaction potential and ground settlement for reclaimed sites. The effective stress model can simulate the stiffness degradation due to excess pore pressure and resulting ground deformation. It is applicable to a wide range of strain. An equivalent linear analysis suitable for low strain levels was also carried out to compare the effective stress analysis. Shear stress ratio calculated from an equivalent linear analysis was used to determine SPT blow count to prevent liquefaction. Depending on the magnitude of potential earthquake and fine contents, the SPT blow count was converted into an equivalent cone tip resistance. It was compared with the measured cone tip resistance. The measured elastic shear wave velocity and cone tip resistance from two reclaimed sites in Incheon were used to perform liquefaction analyses. Two liquefaction evaluation methods showed similar liquefaction potential which was evaluated continuously. The predicted excess pore pressure ratio of upper 20 m was between 40% and 70%. The calculated post-shaking settlement caused by excess pore pressure dissipation was less than 10 cm.

Opticla Angle Sensor Using Pseudorandom-code And Geometry-code (슈도 랜덤 코드와 기하학 코드를 이용한 광학적 Angle Sensor)

  • 김희성;도규봉
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.41 no.2
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    • pp.27-32
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    • 2004
  • Absolute optical angle sensor is described that is an essentially digital opto-electronic device. Its purpose is to resolve the relative and absolute angle position of coded disk using Pseudorandom-code and Geometry-code. In this technique, the angular position of disk is determined in coarse sense first by Pseudorandom-code. A further fine angular position data based on Pixel count is obtained by Geometry-code which result 0.006$^{\circ}$ resolution of the system provided that 7 ${\mu}{\textrm}{m}$ line image sensor are used. The proposed technique is novel in a number of aspects, such that it has the non-contact reflective nature, high resolution of the system, relatively simple code pattern, and inherent digital nature of the sensor. And what is more the system can be easily modified to torque sensor by applying two coded disks in a manner that observe the difference in absolute angular displacement. The digital opto-electronic nature of the proposed sensor, along with its reporting of both torque and angle, makes the system ideal for use in intelligent vehicle systems. In this communication, we propose a technique that utilizes Pseudorandom-code and Geometry-code to determine accurate angular position of coded disk. We present the experimental results to demonstrate the validity of the idea.

Primary Splenic Paraganglioma in a Dog

  • An, Su-Jin;Moon, Jong-Hyun;Hwang, Tae-Sung;Lee, Hee-Chun;Yu, Do-Hyeon;Sur, Jung-Hyang;Jung, Dong-In
    • Journal of Veterinary Clinics
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    • v.35 no.4
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    • pp.155-160
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    • 2018
  • A 6-year-old intact female Shih-tzu dog was referred due to anorexia. Physical examination, complete blood count, serum chemical analysis, radiography, and ultrasonography were evaluated. Physical examination and hematological analysis showed normal findings. Abdominal radiographs and ultrasound revealed well-defined masses in the spleen. Other abdominal organs showed no significant abnormalities. Tissue samples taken via sono-guided fine needle aspiration of the splenic mass showed many bare nuclei, which were variable in size. Results of histopathological and immunohistochemical (IHC) analyses performed after splenectomy were consistent with paraganglioma. Based on these findings, we diagnosed this patient with a paraganglioma of splenic origin. Two months after splenectomy, abdominal ultrasonography revealed a new neoplastic lesion in the liver. The clients refused further management and the patient expired three months after initial diagnosis. Necropsy as well as histopathological and IHC examinations of other systemic organs including the liver, adrenal gland, kidney, brain, urinary bladder, lung, aortic body, carotid body, and pancreas were performed. The neoplastic tissue in the liver also demonstrated features of a paraganglioma, and there were no remarkable findings in all other organs.

CAPABILITY OF THE FAST IMAGING SOLAR SPECTROGRAPH ON NST/BBSO FOR OBSERVING FILAMENTS/PROMINENCES AT THE SPECTRAL LINES Hα, Ca II 8542, AND Ca II K

  • Ahn, Kwang-Su;Chae, Jong-Chul;Park, Hyung-Min;Nah, Jak-Young;Park, Young-Deuk;Jang, Bi-Ho;Moon, Yong-Jae
    • Journal of The Korean Astronomical Society
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    • v.41 no.2
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    • pp.39-47
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    • 2008
  • Spectral line profiles of filaments/prominences to be observed by the Fast Imaging Solar Spectrograph (FISS) are studied. The main spectral lines of interests are $H{\alpha}$, Ca II 8542, and Ca II K. FISS has a high spectral resolving power of $2{\times}10^5$, and supports simultaneous dual-band recording. This instrument will be installed at the 1.6m New Solar Telescope (NST) of Big Bear Solar Observatory, which has a high spatial resolution of 0.065" at 500nm. Adopting the cloud model of radiative transfer and using the model parameters inferred from pre-existing observations, we have simulated a set of spectral profiles of the lines that are emitted by a filament on the disk or a prominence at the limb. Taking into account the parameters of the instrument, we have estimated the photon count to be recorded by the CCD cameras, the signal-to-noise ratios, and so on. We have also found that FISS is suitable for the study of multi-velocity threads in filaments if the spectral profiles of Ca II lines are recorded together with $H{\alpha}$ lines.

Cutaneous Xanthoma in a Dog

  • Yeonhoo Jung;Moonseok Jang;Rahye Kang;Wanghui Lee;Seongjun Park
    • Journal of Veterinary Clinics
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    • v.40 no.5
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    • pp.382-386
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    • 2023
  • A 2-year-old, 12.5 kg, castrated male, mixed-breed dog was presented with a 1-year history of pruritus and progressive alopecia. On physical examination, no remarkable findings were detected including body condition score (5/9). A dermatological examination of the dog revealed generalized erythema, papules or plaques, especially on the face, auricle, dorsum, and shoulder. A fine-needle aspiration of the dorsum and face lesions revealed various numbers of macrophages with foamy cytoplasm and multinucleated giant cells. A bacterial culture test showed the growth of Staphylococcus pseudintermedius. A complete blood cell count was unremarkable and biochemical abnormalities included hyperglobulinemia (4.8 g/dL, reference interval 2.5-4.5 g/dL), mild hypertriglyceridemia (277 mg/dL, reference interval 10-100 mg/dL) and mild hypercholesterolemia (383 mg/dL, reference interval 110-320 mg/dL). Additional diagnostic tests were performed to identify the underlying cause of hyperlipidemia. Canine pancreatic lipase immunoreactivity (<50 ng/mL, reference interval 0-200 ng/mL) and total T4 (1.4 ㎍/dL, reference interval 1.1-5.6 ㎍/dL) were within the reference intervals. For a definitive diagnosis, skin biopsy specimen was collected from the papular lesions on the dorsum by using a 4 mm biopsy punch. A histopathological examination revealed numerous large macrophages with abundant foamy cytoplasm in the dermis. The foamy macrophages were located diffusely between the collagen fibers. Extracellular amorphous lipid deposits were also presented in the dermal tissue. A definitive diagnosis of cutaneous xanthoma was made based on clinical signs and cytological and histopathological results.

Effects of Inhalable Microparticles of Socheongryong-tang on Chronic Obstructive Pulmonary Disease in a Mouse Model (COPD 동물 모델에서 소청룡탕 흡입제형의 효과)

  • Lee, Eung-Seok;Han, Jong-Min;Kim, Min-Hee;Namgung, Uk;Yeo, Yoon;Park, Yang-Chun
    • The Journal of Korean Medicine
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    • v.34 no.3
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    • pp.54-68
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    • 2013
  • Objectives: This study aimed to evaluate the effects of microparticles of Socheongryong-tang (SCRT) on chronic obstructive pulmonary disease (COPD) in a mouse model. Methods: The inhalable microparticles containing SCRT were produced by spray-drying with leucine as an excipient, and evaluated with respect to the aerodynamic properties of the powder by Andersen cascade impactor (ACI). Its equivalence to SCRT extract was evaluated using lipopolysaccharide (LPS) and a cigarette-smoking (CS)-induced murine COPD model. Results: SCRT microparticles provided desirable aerodynamic properties (fine particle fraction of $49.6{\pm}5.5%$ and mass median aerodynamic diameter of $4.8{\pm}0.3{\mu}m$). SCRT microparticles did not show mortality or clinical signs over 14 days. Also there were no significant differences in body weight, organ weights or serum chemical parameters between SCRT microparticle-treated and non-treated groups. After 14 days the platelet count significantly increased compared with the non-treated group, but the values were within the normal range. Inhalation of SCRT microparticles decreased the rate of neutrophils in blood, granulocytes in peripheral blood mononuclear cells (PBMC) and bronchoalveolar lavage fluid (BALF) and level of TNF-${\alpha}$ and IL-6 in BALF on COPD mouse model induced by LPS plus CS. This effect was verified by histological findings including immunofluorescence staining of elastin, collagen, and caspase 3 protein in lung tissue. Conclusions: These data demonstrate that SCRT microparticles are equivalent to SCRT extract in pharmaceutical properties for COPD. This study suggests that SCRT microparticles would be a potential agent of inhalation therapy for the treatment of COPD.