• Title/Summary/Keyword: field trial

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A study on the space kineticism (공간의 키네티시즘에 관한 연구)

  • 임혜선;김주연
    • Korean Institute of Interior Design Journal
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    • no.30
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    • pp.28-34
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    • 2002
  • We need to think that space is not static but dynamic because it becomes wide and narrow, newly appears and disappears by human's behavior. Generally such movement in a space is a thing of feeling and dynamic about movement. But it is extending the experience of the subject by scientific technique's development and anticipation about the feature. The practical movement is actively introduced into architecture and interior design scope and occurs a trial about this movement. By using four elements -a form, hue, movement, light- kineticism becomes visual arts united with art and science. It recovers the art's sociality and arises participation of spectators. In the environment and art field kineticism is not simple ostentation but a current trial for human's mind and sensitivility. Kineticism is four-dimensional space considered by human's experience and is related to an observer, or experiential subject of space. Now the space except human's mind feature re-illuminates kineticism, that is, the field of the formative arts in the early part of the 20th century and gets to be 'the consensus space'.

An Investigation about the Present States of Clinical Trial for Traditional Medicine in Korea, China, Taiwan and Japan (한국과 중국, 대만, 일본의 전통약 임상시험 현황에 대한 연구)

  • Lee, Kyun-Goo;Bae, Sun-Hee;Shin, Hyeon-Kyoo
    • Korean Journal of Oriental Medicine
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    • v.12 no.1
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    • pp.13-22
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    • 2006
  • Background and Aims: Herbal drugs and traditional medicines have lately attracted considerable attention by global pharmaceutical corporations because the conventional chemical drugs didn't work well for many chronic diseases or intractable diseases. The government of Korea is also supporting to develop the new drug which is high value added product, and the natural medicine including herbal medicine(or Traditional Korean Medicine) have a significant presence in this field. non-clinical pharmacology/toxicology study and clinical trial are the two major criteria which estimate efficacy and safety for registration of new drugs. All of the pharmaceutical companies producing herbal medicine and the academic and the academic world of Tradition Korean Medicine have the will to develop new herbal drugs, but there are obstacles that they have neither experience nor guideline about clinical trial. Therefore for developing new herbal drugs, it is necessary to research the present conditions and comprehensive systems about clinical trial in Northeast Asian countries China, Taiwan and Japan because they have the common background with Korea in traditional medicine fields. Methods : The present state of clinical trial for herbal medicine in Korea was investigated. And then, those in China, Taiwan, Japan was also investigated. Results and conclusions : There are significant differences among 4 Southeast Asian countries Korea, China, Taiwan and Japan each in present condition, purpose, involved comprehensive system including legislation, and actual operation of clinical trial for traditional medicine.

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Trial Installation and Performance Evaluation of Prefabricated Concrete Slab Track on Revenue Line (프리캐스트 콘크리트 슬래브궤도의 영업선 시험시공 및 성능평가)

  • Jang, Seung-Yup;Kang, Yun-Suk;Lee, Hu-Sam;Kim, Yu-Bong;Lee, Jong-Soo
    • Proceedings of the KSR Conference
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    • 2008.11b
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    • pp.840-845
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    • 2008
  • To develop our original technology of concrete slab track, being widely accepted for new track, prefabricated concrete slab track, or precast concrete slab track has been developed. They have two different types according to slab shape and its dimensions, connection of slabs and connecting structure onto substructure. After the system design and successful performance evaluation in the laboratory, the trial installation on revenue line has been carried out. This paper is presenting the result of the trial installation and the performance tests in field. The performance tests have been performed as visual inspection for cracks and damages, measurement of track alignment and elastic behavior of track under passing trains. The performance test results during last 2 years have shown that no remarkable damages and settlements were found, and track alignment and elastic track behavior both exhibits good status.

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A Field Trial of Norfloxacin on Bovine, Swine and Poultry with Respiratory Diseases and Diarrhea (소, 돼지, 닭의 호흡기병과 설사에 대한 Norfloxacin 주사 및 경구용 제제의 야외치료시험)

  • 손봉환;황현순;김정훈;한태호;배도권
    • Korean Journal of Veterinary Service
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    • v.14 no.2
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    • pp.159-174
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    • 1991
  • A field trial of norfloxacin on bovine 206, swine 222 and poultry 205 with respiratory diseases and diarrhea was conducted from Sept 1, 1990 to Jan 30, 1991 in Inchon and Kyonggi-do. The results are as follows. 1. Guinea pigs and rabbits were dosages 10 and 20 times normal. Ten days of observation saw no side effect. 2. Oral treatment on bovine, swine and poultry showed a curing rate of 82.00∼89.06%(Mean 86.00%), compared with 87.27∼96.36%(Mean 92.24%) by Injection. 3. The curing rate was 81.92% by the fourth treatment. 4. The curing rate with and without the use of adjuvant was 80.00∼100% and 83.60∼93. 10%, respectively, for swine, and 81.82∼100% and 82.00∼97.14% for bovine. 5. The curing rate was more dependent on seriousness of illness, environment and time than age. 6. The main disease causing bacteria of bovine respiratory diseases: Haemolytic Sta 27.62%, Haemolytic Str 33.33%, sum of this bacteria is 60.95%, diarrhea: Haemolytic coliform 80.20%, swine respiratory diseases; Haemophilus Spp 20.95%, Haemolytic Sta 72%, Haemolytic Str 21.90%, Sum of these bacteria is 68.57%, diarrhea; Haemolytic coliform 57.26%, poultry respiratory diseases; mycoplasma Spp 29.52%, Haemolytic Sta 13.33%, Sum of this bacteria is 42.85%, diarrhea; Haemolytic coliform 53.00%. 7. The curing rate of norfloxacin by species of strain, the unidentified bacteria on bovine respiratory diseases was the lowest with 77.78%, the others ranged from 84.21% to 100% with most of them over 90%. 8. The loss of clinical sign on bovine and swine was the highest when after 2∼4 application. 9. In terms of antibiotic sensitivity test, norfloxacin was the highest with 84.62∼100% (mean 90.09%) among eight bacterias, only 5 of 15 antibiotics had a sensitivity of over 56.25%, showing a high degree of tolerance.

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Comparison of Efficiency between Individual Randomization and Cluster Randomization in the Field Trial (지역사회 임상시험시 개인별 무작위배정과 군집 무작위배정의 효율성 비교)

  • Koo, Hye-Won;Kwak, Min-Jeong;Lee, Young-Jo;Park, Byung-Joo
    • Journal of Preventive Medicine and Public Health
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    • v.33 no.1
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    • pp.51-55
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    • 2000
  • Objectives . In large-scale field trials, randomization by cluster is frequently used because of the administrative convenience, a desire to reduce the effect of treatment contamination, and the need to avoid ethical issues that might of otherwise arise. Cluster randomization trials are experiments in which intact social unit, e.g., families, schools, cities, rather than independent individuals are randomly allocated to intervention groups. The positive correlation among responses of subjects from the same cluster is in matter in cluster randomization. This thesis is to compare the results of three randomization methods by standard error of estimator of treatment effect. Methods : We simulated cholesterol data varing the size of the cluster and the level of the correlation in clusters and analyzed the effect of cholesterol-lowering agent. Results : In intra-cluster randomization the standard error of the estimator of treatment effect is smallest relative to that in inter-cluster randomization and that in individual randomization. Conclusions : Infra-cluster randomization is the most efficient in its standard error of estimator of treatment effect but other factor should be considered when selecting a specific randomization method.

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An Estimation of Behavior for Wedge type Removable Soil Nailing System by Field Trial Construction (현장시험시공을 통한 쐐기형 제거식 쏘일네일링 공법의 거동 평가)

  • Han, Yeon-Jin;Park, Si-Sam;Kwon, Hyuk-Jun;Kim, Hong-Taek;Park, Ju-Seok
    • Proceedings of the Korean Geotechical Society Conference
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    • 2009.09a
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    • pp.1360-1364
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    • 2009
  • Necessity of removable soil nailing has been arisen in the soil nailing system because of problem such as civil petition for geotechnical environment and invasion of the ground boundary line and payments for use besides geotechnical engineering. Removable soil nailing system is improved soil nailing system that fixed socket arranged in boring hole for increasement of skin friction. In this study, field pull-out tests are carried out more 4 times considering installed distance of fixed socket and analyze skin friction behavior characteristics in fixed socket through analysis of measurements of strain gauge attached to fixed socket. Also, to evaluate application for wedge type removable soil nailing system analyzing displacement aspects through field pull-out tests by trial construction.

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Geosynthetic-Reinforced Segmental Retaining Walls in Tiered Arrangement - Case Study and Field Trial Wall Instrumentation (다단식 보강토 옹벽의 설계 - 사례연구 및 시험시공)

  • Yoo, Chung-Sik;Jung, Hyuk-Sang
    • Journal of the Korean Geosynthetics Society
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    • v.3 no.1
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    • pp.27-36
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    • 2004
  • This paper presents the results of stability analyses on soil-reinforced segmental retaining walls in a tiered arrangement. Four different walls were examined to investigate the appropriateness of their designs within the context of the current design guidelines based on limit equilibrium. Slope stability analysis against the compound failure mode, which is frequently ignored during design, was also performed based on the method recommended by FHWA design guidelines. Also presented are the results of instrumentation on a full-scale field trial wall constructed as part of this study. The implications of the findings from this study are discussed.

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Current Status of N-of-1 Trials for Herbal Medicine -Literature Review (한약에 대한 N-of-1 임상시험의 현황 - 문헌 고찰)

  • Jeung, Chang-woon;Jeon, Sun-woo;Jo, Hee-Geun
    • The Journal of Korean Medicine
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    • v.41 no.1
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    • pp.107-116
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    • 2020
  • Objectives: To overcome the limitations of randomized controlled trials, many other trials design is tested. The n-of-1 trial is a promising research method in the field of Korean medicine because of this methodology can examine the optimal treatment for each patient strictly. Therefore, we reviewed the status of N-of-1 studies on herbal medicine. Methods: A systematic literature review was conducted based on the pubmed database. The search term were 'N-of-1 Trial', 'Chinese Medicine', 'Herbal Medicine', 'Kampo'. There was no restriction in year. Results: Four clinical trials have been identified to demonstrate the effectiveness of herbal medicines for Kidney-yin-deficiency syndrome, bronchiectasis and gastric cancer. These studies suggest that the N-of-1 design is a study that encourages patient involvement, demonstrates the effectiveness of herbal medicines and helps reduce unnecessary medication. Conclusion: The N-of-1 clinical trial may be a rigorous methodology suitable for the clinical setting and may help the development of evidence-based Korean medicine. Attention is also needed in this research method in Korea.

Studies on the Processing Factors of Pesticide in Dried Carrot from Field Trial and Dipping Test (포장 및 침지실험 당근의 건조에 의한 농약 가공계수 산출 연구)

  • Park, Kun-Sang;Suh, Jung-Hyuck;Choi, Jeong-Heui;Kim, Sun-Gu;Lee, Hyo-Ku;Shim, Jae-Han
    • The Korean Journal of Pesticide Science
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    • v.13 no.4
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    • pp.209-215
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    • 2009
  • This study was performed to produce the processing factors of pesticides in dried carrot. It is essential data for establishing the maximum residue limits (MRLs) of pesticides in dried carrot. The target pesticides were azinphos-methyl, chlorpyrifos, captan, endosulfan and triclorfon. These pesticides are included Korea's MRL list in carrot and USA's MRL list in dried foods. To infiltrate these pesticides up to each MRL level in carrot, the dipping test was performed in laboratory. Also, the supervised residue trial of the pesticide for carrot was conducted in the green house to recognize the field trial's tendency. In the dipping test in laboratory (including drying examination), the processing factors of the carrot at various concentrations and temperatures could be evaluated. In field test, the processing factors were 5.9 for azinphos-methyl, 1.7 for captan, 7.6 for chlorpyrifos, 6 for endosulfan, 0 for trichlorfon, respectively. The dipping test in laboratory on various kinds of conditions showed more precise processing factors than field trial. The processing factors obtained from the dipping test of carrot were 0~4.7 at the various concentration of the pesticides, and 0~6.7 at various drying temperature. The lower level processing factors were 0~0.6 for trichlorfon and the higher level were 3.0~5.8 for chlorpyrifos. The highest processing factor was 9.1 for captan.

A Study on Developing the Evaluation Indicators for Academic Libraries (대학도서관 평가지표 개발 연구)

  • Kwak, Chul-Wan;Kwack, Dong-Chul;Noh, Dong-Jo;Noh, Young-Hee
    • Journal of the Korean Society for Library and Information Science
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    • v.42 no.2
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    • pp.147-170
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    • 2008
  • Evaluation of an academic library is a key to its success. Library and Information Policy Bureau of the President of the Republic of Korea conducted a trial evaluation on academic libraries with a university evaluation index developed by KERIS in 2005. The committee decided to review its feasibility based on the feedbacks from the academic libraries after the trial. This study aims to address the indexing issues appeared during the trial and suggest a new evaluation index tailored to academic libraries. First, the evaluation field is condensed from 7 to 6 as "financing" and "infrastructure" are integrated into "budget and infrastructure." Secondly, both "user charter" and "planning" are removed from the "library management" field category. and "library self-assessment" is added instead. In "information resource" field, "non-books and etc." is added. Third, evaluation categories for "budget and infrastructure" field are altered to budget-related items and library equipment. Forth, "collection turnover rate" category is incorporated into "collection usage" in "information usage" field, and "library use rate" in "information service" field is moved to "information resource" field and renamed as "use rate."