• 제목/요약/키워드: field trial

검색결과 655건 처리시간 0.037초

공간의 키네티시즘에 관한 연구 (A study on the space kineticism)

  • 임혜선;김주연
    • 한국실내디자인학회논문집
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    • 제30호
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    • pp.28-34
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    • 2002
  • We need to think that space is not static but dynamic because it becomes wide and narrow, newly appears and disappears by human's behavior. Generally such movement in a space is a thing of feeling and dynamic about movement. But it is extending the experience of the subject by scientific technique's development and anticipation about the feature. The practical movement is actively introduced into architecture and interior design scope and occurs a trial about this movement. By using four elements -a form, hue, movement, light- kineticism becomes visual arts united with art and science. It recovers the art's sociality and arises participation of spectators. In the environment and art field kineticism is not simple ostentation but a current trial for human's mind and sensitivility. Kineticism is four-dimensional space considered by human's experience and is related to an observer, or experiential subject of space. Now the space except human's mind feature re-illuminates kineticism, that is, the field of the formative arts in the early part of the 20th century and gets to be 'the consensus space'.

한국과 중국, 대만, 일본의 전통약 임상시험 현황에 대한 연구 (An Investigation about the Present States of Clinical Trial for Traditional Medicine in Korea, China, Taiwan and Japan)

  • 이경구;배순희;신현규
    • 한국한의학연구원논문집
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    • 제12권1호
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    • pp.13-22
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    • 2006
  • Background and Aims: Herbal drugs and traditional medicines have lately attracted considerable attention by global pharmaceutical corporations because the conventional chemical drugs didn't work well for many chronic diseases or intractable diseases. The government of Korea is also supporting to develop the new drug which is high value added product, and the natural medicine including herbal medicine(or Traditional Korean Medicine) have a significant presence in this field. non-clinical pharmacology/toxicology study and clinical trial are the two major criteria which estimate efficacy and safety for registration of new drugs. All of the pharmaceutical companies producing herbal medicine and the academic and the academic world of Tradition Korean Medicine have the will to develop new herbal drugs, but there are obstacles that they have neither experience nor guideline about clinical trial. Therefore for developing new herbal drugs, it is necessary to research the present conditions and comprehensive systems about clinical trial in Northeast Asian countries China, Taiwan and Japan because they have the common background with Korea in traditional medicine fields. Methods : The present state of clinical trial for herbal medicine in Korea was investigated. And then, those in China, Taiwan, Japan was also investigated. Results and conclusions : There are significant differences among 4 Southeast Asian countries Korea, China, Taiwan and Japan each in present condition, purpose, involved comprehensive system including legislation, and actual operation of clinical trial for traditional medicine.

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프리캐스트 콘크리트 슬래브궤도의 영업선 시험시공 및 성능평가 (Trial Installation and Performance Evaluation of Prefabricated Concrete Slab Track on Revenue Line)

  • 장승엽;강윤석;이후삼;김유봉;이종수
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2008년도 추계학술대회 논문집
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    • pp.840-845
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    • 2008
  • To develop our original technology of concrete slab track, being widely accepted for new track, prefabricated concrete slab track, or precast concrete slab track has been developed. They have two different types according to slab shape and its dimensions, connection of slabs and connecting structure onto substructure. After the system design and successful performance evaluation in the laboratory, the trial installation on revenue line has been carried out. This paper is presenting the result of the trial installation and the performance tests in field. The performance tests have been performed as visual inspection for cracks and damages, measurement of track alignment and elastic behavior of track under passing trains. The performance test results during last 2 years have shown that no remarkable damages and settlements were found, and track alignment and elastic track behavior both exhibits good status.

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소, 돼지, 닭의 호흡기병과 설사에 대한 Norfloxacin 주사 및 경구용 제제의 야외치료시험 (A Field Trial of Norfloxacin on Bovine, Swine and Poultry with Respiratory Diseases and Diarrhea)

  • 손봉환;황현순;김정훈;한태호;배도권
    • 한국동물위생학회지
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    • 제14권2호
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    • pp.159-174
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    • 1991
  • A field trial of norfloxacin on bovine 206, swine 222 and poultry 205 with respiratory diseases and diarrhea was conducted from Sept 1, 1990 to Jan 30, 1991 in Inchon and Kyonggi-do. The results are as follows. 1. Guinea pigs and rabbits were dosages 10 and 20 times normal. Ten days of observation saw no side effect. 2. Oral treatment on bovine, swine and poultry showed a curing rate of 82.00∼89.06%(Mean 86.00%), compared with 87.27∼96.36%(Mean 92.24%) by Injection. 3. The curing rate was 81.92% by the fourth treatment. 4. The curing rate with and without the use of adjuvant was 80.00∼100% and 83.60∼93. 10%, respectively, for swine, and 81.82∼100% and 82.00∼97.14% for bovine. 5. The curing rate was more dependent on seriousness of illness, environment and time than age. 6. The main disease causing bacteria of bovine respiratory diseases: Haemolytic Sta 27.62%, Haemolytic Str 33.33%, sum of this bacteria is 60.95%, diarrhea: Haemolytic coliform 80.20%, swine respiratory diseases; Haemophilus Spp 20.95%, Haemolytic Sta 72%, Haemolytic Str 21.90%, Sum of these bacteria is 68.57%, diarrhea; Haemolytic coliform 57.26%, poultry respiratory diseases; mycoplasma Spp 29.52%, Haemolytic Sta 13.33%, Sum of this bacteria is 42.85%, diarrhea; Haemolytic coliform 53.00%. 7. The curing rate of norfloxacin by species of strain, the unidentified bacteria on bovine respiratory diseases was the lowest with 77.78%, the others ranged from 84.21% to 100% with most of them over 90%. 8. The loss of clinical sign on bovine and swine was the highest when after 2∼4 application. 9. In terms of antibiotic sensitivity test, norfloxacin was the highest with 84.62∼100% (mean 90.09%) among eight bacterias, only 5 of 15 antibiotics had a sensitivity of over 56.25%, showing a high degree of tolerance.

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지역사회 임상시험시 개인별 무작위배정과 군집 무작위배정의 효율성 비교 (Comparison of Efficiency between Individual Randomization and Cluster Randomization in the Field Trial)

  • 구혜원;곽민정;이영조;박병주
    • Journal of Preventive Medicine and Public Health
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    • 제33권1호
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    • pp.51-55
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    • 2000
  • Objectives . In large-scale field trials, randomization by cluster is frequently used because of the administrative convenience, a desire to reduce the effect of treatment contamination, and the need to avoid ethical issues that might of otherwise arise. Cluster randomization trials are experiments in which intact social unit, e.g., families, schools, cities, rather than independent individuals are randomly allocated to intervention groups. The positive correlation among responses of subjects from the same cluster is in matter in cluster randomization. This thesis is to compare the results of three randomization methods by standard error of estimator of treatment effect. Methods : We simulated cholesterol data varing the size of the cluster and the level of the correlation in clusters and analyzed the effect of cholesterol-lowering agent. Results : In intra-cluster randomization the standard error of the estimator of treatment effect is smallest relative to that in inter-cluster randomization and that in individual randomization. Conclusions : Infra-cluster randomization is the most efficient in its standard error of estimator of treatment effect but other factor should be considered when selecting a specific randomization method.

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현장시험시공을 통한 쐐기형 제거식 쏘일네일링 공법의 거동 평가 (An Estimation of Behavior for Wedge type Removable Soil Nailing System by Field Trial Construction)

  • 한연진;박시삼;권혁준;김홍택;박주석
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2009년도 세계 도시지반공학 심포지엄
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    • pp.1360-1364
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    • 2009
  • Necessity of removable soil nailing has been arisen in the soil nailing system because of problem such as civil petition for geotechnical environment and invasion of the ground boundary line and payments for use besides geotechnical engineering. Removable soil nailing system is improved soil nailing system that fixed socket arranged in boring hole for increasement of skin friction. In this study, field pull-out tests are carried out more 4 times considering installed distance of fixed socket and analyze skin friction behavior characteristics in fixed socket through analysis of measurements of strain gauge attached to fixed socket. Also, to evaluate application for wedge type removable soil nailing system analyzing displacement aspects through field pull-out tests by trial construction.

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다단식 보강토 옹벽의 설계 - 사례연구 및 시험시공 (Geosynthetic-Reinforced Segmental Retaining Walls in Tiered Arrangement - Case Study and Field Trial Wall Instrumentation)

  • 유충식;정혁상
    • 한국지반신소재학회논문집
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    • 제3권1호
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    • pp.27-36
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    • 2004
  • 본 논문에서는 다단식보강토옹벽의 해석과 시험 시공을 통해 안정성을 검토한 내용을 다루었다. 한계평형에 근간을 둔 현행의 설계기준에 근거하여 설계된 각기 다른 네 개의 현장 옹벽에 대해 내 외적 안정성 대한 안정성 검토를 실시하였으며, 국외 보강토옹벽의 설계법인 FHWA 및 NCMA의 설계에 의거한 다단식보강토옹벽의 시험시공을 통해 상 하단 옹벽의 상호작용에 의한 거동에 대해 분석을 실시하였다. 본 논문에서는 연구결과를 토대로 다단식보강토옹벽의 역학적 거동을 이해하고, 설계 및 시공의 주안점을 언급하였다.

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한약에 대한 N-of-1 임상시험의 현황 - 문헌 고찰 (Current Status of N-of-1 Trials for Herbal Medicine -Literature Review)

  • 정창운;전선우;조희근
    • 대한한의학회지
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    • 제41권1호
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    • pp.107-116
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    • 2020
  • Objectives: To overcome the limitations of randomized controlled trials, many other trials design is tested. The n-of-1 trial is a promising research method in the field of Korean medicine because of this methodology can examine the optimal treatment for each patient strictly. Therefore, we reviewed the status of N-of-1 studies on herbal medicine. Methods: A systematic literature review was conducted based on the pubmed database. The search term were 'N-of-1 Trial', 'Chinese Medicine', 'Herbal Medicine', 'Kampo'. There was no restriction in year. Results: Four clinical trials have been identified to demonstrate the effectiveness of herbal medicines for Kidney-yin-deficiency syndrome, bronchiectasis and gastric cancer. These studies suggest that the N-of-1 design is a study that encourages patient involvement, demonstrates the effectiveness of herbal medicines and helps reduce unnecessary medication. Conclusion: The N-of-1 clinical trial may be a rigorous methodology suitable for the clinical setting and may help the development of evidence-based Korean medicine. Attention is also needed in this research method in Korea.

포장 및 침지실험 당근의 건조에 의한 농약 가공계수 산출 연구 (Studies on the Processing Factors of Pesticide in Dried Carrot from Field Trial and Dipping Test)

  • 박건상;서정혁;최정희;김선구;이효구;심재한
    • 농약과학회지
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    • 제13권4호
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    • pp.209-215
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    • 2009
  • 이 연구는 건조 당근의 농약잔류허용기준설정에 필수자료인 건조에 의한 농약의 가공계수를 산출을 위하여 실시하였다. 가공계수 산출 대상 농약은 우리나라에서 당근 중에 기준이 설정되어 있고 미국에서는 건조농산물 중에 기준이 설정된 농약인 azinphos-methyl, chlorpyrifos, captan, endosulfan, triclorfon으로 하였다. 당근에 각 대상 농약을 기준치 정도로 침투시키기 위하여 실험실에서 농약 첨가액을 사용하여 침지실험을 하였고 또한 포장재배시의 경향을 알아보기 위하여 온실에서 농약을 살포하여 재배하였다. 침지실험은 실험실에서 다양한 침지농도와 온도에서 실험하였다. 포장 재배한 당근의 농약 가공계수는 azinphos-methyl 5.9, captan 1.7, chlorpyrifos 7.6, endosulfan 6, trichlorfon 0 이었다. 실험실에서 포장 시험보다 더 정확한 가공계수를 얻고자 각 농산물을 농약액에 침지하여 여러 가지 조건으로 실험한 결과, 당근의 침지농도별 가공계수는 농약에 따라 0~4.7, 건조온도별 가공계수는 0~6.7 이었다. Trichlorfon은 가공계수가 낮은 수준으로 0~0.6을 보였고 chlorpyrifos의 가공계수는 3.0~5.8로 높은 수준이었으며 가장 높은 가공계수는 captan 9.1 이었다.

대학도서관 평가지표 개발 연구 (A Study on Developing the Evaluation Indicators for Academic Libraries)

  • 곽철완;곽동철;노동조;노영희
    • 한국문헌정보학회지
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    • 제42권2호
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    • pp.147-170
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    • 2008
  • 대학도서관 평가는 대학도서관의 수준 향상을 위한 기본전략이라고 할 수 있다. 이에 대통령 직속 도서관정보정책위원회에서는 2005년도에 한국교육학술정보원에서 개발된 대학평가지표를 이용하여 시범평가를 함으로써 대학도서관들의 의견을 수렴하여 평가지표의 타당성과 실효성을 검증하고 향후 적용 방안에 대한 시사점을 얻고자 하였다. 그 결과 평가항목 및 지표부분에 있어서 시정사항이 요구되었으며, 본 연구는 시범평가에서 나타난 문제점을 해결하고 대학도서관에 적용할 수 있는 평가지표를 제시하고자 하였다. 평가지표 세부수정내용은 첫째 평가분야를 7개 분야에서 재화자원과 시설자원을 '예산 및 시설자원'으로 통합하여 6개 분야로 줄였다. 둘째, '도서관경영' 분야의 '이용자헌장과 '기획' 항목을 제거하고 '도서관 자체평가' 항목을 추가하였으며, '정보자원' 분야에서 '비도서 및 기타자료' 평가항목을 추가하였다. 셋째, 재화자원 및 시설자원을 통합하여 '예산 및 시설'로 하였으며 평가지표는 예산항목과 도서관시설로 수정하였다. 넷째, '정보이용' 분야에서 '장서회전율'을 '장서이용'에 통합시키고. '정보서비스'분야의 '도서관 이용율' 항목을 '정보자원' 분야로 이동시킨 후 '이용율'로 항목이름을 바꾸었다.