• The Journal of Engineering Geology
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• v.32 no.3
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• pp.351-361
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• 2022

Numerical analysis performed to predict the behavior of Ipseok-dae columnar joints in Mudeungsan National Park to understand their stability and movement. The numerical analysis technique, 3DEC, is based on the discrete element method that can analysis discontinuities. The analysis used data for material properties derived from laboratory tests, which found that average density was 2.68 kN/m³, average normal stiffness was 3.15 GPa/m, average shear stiffness was 1.00 GPa/m, average cohesion was 0.51 MPa, and the average friction angle was 33°. The Ipseok-dae columnar joints were modeled on the basis of the field survey data for 15 joints located between the observation platform and the hiking trail. The numerical analysis assessed the behavior of each columnar joint by interpreting the displacement of the edges of its upper and lower surfaces. The greatest maximum displacement was found in columnar joint No. 6, and the greatest minimum displacement was found in joint No. 11. Analyzing the movements of five discontinuities in joint No. 11 indicated that the maximum displacement occurred at the 2nd level. The other levels were ordered 5th, 4th, 1st, and 3rd in terms of subsequent greatest displacements. Considering the total displacement in the 15 studied joints, the Ipseok-dae columnar joints are judged to be stable. However, considering the cultural and historical value of Mudeungsan National Park, it is regarded that the currents slope stability should be maintained by monitoring the individual rock blocks of the joints.

• Journal of Space Technology and Applications
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• v.2 no.2
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• pp.81-103
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• 2022

In this paper, the contents of the design and development process of the 6U micro-satellite Snipe (SNIPE, national name Toyosat; small scale magnetospheric and Ionospheric plasma experiment ), which was developed to observe the near-global space environment through polarization flight for the first time in Korea, were described. Snipe performs transversal flight to observe the Earth's surrounding space environment in three dimensions, and aims to simultaneously observe the space plasma density and temperature in the ionosphere, as well as temporal changes in the solar magnetic field and electromagnetic waves. In this way, it was developed by dividing it into a test certification model (EQM) and a flight model (FM) to perform the actual mission for at least six months, away from developing a cube satellite for short-term space technology verification or manpower training. Currently, Snipe, which has completed the development of a total of four FM and completed all space environment tests, is scheduled to launch 2023. In this paper, we introduce the design contents and development process of the Snipe satellite body ahead of launch, and hope that it will be a useful reference for the development of 6U-class micro-satellite for full-scale mission in Korea.

• Journal of Pharmacopuncture
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• v.25 no.3
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• pp.233-241
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• 2022

Objectives: Asthma is a chronic disease, and the demand for herbal medicines in this field has increased in recent years. The new findings highlight the role of the gut-lung axis in the pathophysiology of asthma. Hence, this study will evaluate the safety and efficacy of Glasthma syrup, an herbal formula based on Persian medicine, in improving asthma and regulating intestinal permeability. The formula consists of five herbal ingredients that have anti-inflammatory effects on the respiratory tract, also known as gut tonics. Methods: The study will be conducted as a placebo-controlled, triple-blind, randomized trial. It will consist of a 4-week intervention followed by a 4-week follow-up period. The target sample size is 20 patients with moderate asthma aged 18 to 60 years. Eligible participants will be randomly assigned to either the experimental group or the control group in equal numbers. Patients in the experimental group will take Glasthma syrup (7.5 mL, twice a day), while patients in the control group will take a matching placebo. Both groups will receive a 4-week combination of a long-acting beta2 agonist and a leukotriene modulator as standard of care. Inhaled corticosteroids can be used as rescue medication as needed. Results: The primary outcomes are asthma symptom scale, lung function, and intestinal permeability. Secondary outcomes include quality of life, symptom recurrence rates, and blood tests. A safety assessment will also be conducted during the trial. Conclusion: In this trial, the effects of Glasthma syrup in patients with moderate asthma will be examined. The study will also assess the effects of the formulation on the gut-lung axis by simultaneously monitoring the gut permeability index, asthma symptoms, and lung function.

• Journal of the Korean GEO-environmental Society
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• v.23 no.9
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• pp.5-16
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• 2022

In recent years due to the development of urban and underground space, the number of ground disasters is increasing, and it is also leading to social problems. To solve the problem, a grouting method is generally used. However, the grouting method has material (grout) limitations in permeability, gelation properties and tensile resistance. Therefore, research on grout materials mixed with fibers is actively carried out to improve the problems. However, in the actual ground injection process, many difficulties have been faced causing the blockage of the inlet port and the injection tube. In this study, 'CNT-mixed grout material' was developed using CNT powder that can reinforce the tensile strength of soils. The uniaxial compressive and tensile strength tests were performed to obtain the optimal content and mechanical properties of the CNT Powder-mixed grout. It was found that the optimal CNT powder content is 0.5% that gives the average maximum strength. A one-dimensional injection test and the bulb formation test were carried out, and it was identified that the injection rate and bulb form could be controlled by pressure and mixing ratio. Field application of the CNT-Mixed grout is simulated using numerical analysis of slopes, foundations, and tunnels reinforced in several types. The positive effect of reducing plastic ranges and settlements was confirmed.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.spc
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• pp.11-17
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• 2022

In this study, we address the development of a floating platform system based on a unmanned surface vessel for wide-area sensing and monitoring of hazardous and noxious substances (HNSs). For long endurance, a movable floating platform with no mooring lines was used and modified for HNS sensing and monitoring. The floating platform was equipped with various sensors such as optical and thermal imaging cameras, marine radar, and sensors for detecting HNSs in water and air. Additionally, for experiment validation in real outdoor environments, a portable gas-exposure system (PGS) was built and installed on the monitoring system. The software for carrying out the mission was integrated with the Robot Operating System (ROS) framework. The practical feasibility of the developed system was verified through experimental tests conducted in inland water and real-sea environments.

• Korean Journal of Clinical Laboratory Science
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• v.55 no.1
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• pp.45-51
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• 2023

Canine parvovirus type 2 (CPV-2) and canine coronavirus (CCoV) are major pathogens that can induce gastroenteritis in dogs. They are highly contagious and have a high morbidity rate. There are no specific treatments available for them to date. Therefore, rapid and accurate diagnosis becomes essential. The rapid diagnostic test (RDT) for animals can be used widely in the field because it is fast and easy to use for diagnosis. Thus, this study aimed to clinically evaluate and confirm the clinical utility of CPV-2/CCoV RDT. The parameters evaluated included the limit of detection (LoD), cross-reactivity, interference, sensitivity, specificity, negative likelihood ratio (NLR), and kappa value. The results revealed that the LoD values for CPV-2 and CCoV were 9.7×10 50% tissue culture infectious dose (TCID₅₀)/mL and 2.5×10² TCID₅₀/mL, respectively. There was no cross-reactivity with nine pathogens or interference by interfering materials. The RDT showed a sensitivity of 90.0%, a specificity of 100.0%, NLR of 0.1, and a kappa value of 0.90 for diagnosing both viruses. In conclusion, CPV-2/CCoV RDT is useful as a screening test because of its high sensitivity, specificity, kappa value, and low NLR.

• Korean journal of applied entomology
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• v.61 no.4
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• pp.529-537
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• 2022

The susceptibilities of five insecticides to the larvae of Spoladea recurvalis, a major pest of spinach, were evaluated. Lufenuron EC, chromafenozide EC, chlorantraniliprole WP, tebufenozide WP, and pyridalyl EW showed 90% or more insecticidal activity at dilution concentrations of 2 (12.5 ppm), 4 (12.5 ppm), 8 (2.5 ppm), 4 (20.0 ppm), and 8 (12.5 ppm), respectively. At their recommended concentrations, Chromafenozide EC, chlorantraniliprole WP, tebufenozide WP, and pyridalyl EW showed very high insecticidal activity of 98.3%, 100%, 95.0%, and 100%, respectively, after 72 h on S. recurvalis larvae exposed after 7 days of treatment. Field tests at two spinach greenhouses in Hwaseong and Yeoncheon showed a high control effect of over 90% after 7 days of treatment in both areas. In addition, the insecticides can be used as exclusive agents for S. recurvalis that occurs in spinach, as there is no phytotoxicity even at double doses.

• Journal of Korean Neurosurgical Society
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• v.66 no.5
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• pp.511-524
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• 2023

Objective : This animal model aimed to compare the rat group that received brain irradiation and did not receive additional treatment (only saline) and the rat group that underwent brain irradiation and received Granulocyte colony stimulating factor (G-CSF) treatment. In addition, the effects of G-CSF on brain functions were examined by magnetic resonance (MR) imaging and histopathologically. Methods : This study used 24 female Wistar albino rats. Drug administration (saline or G-CSF) was started at the beginning of the study and continued for 15 days after whole-brain radiotherapy (WBRT). WBRT was given on day 7 of the start of the study. At the end of 15 days, the behavioral tests, including the three-chamber sociability test, open field test, and passive avoidance learning test, were done. After the behavioral test, the animals performed the MR spectroscopy procedure. At the end of the study, cervical dislocation was applied to all animals. Results : G-CSF treatment positively affected the results of the three-chamber sociability test, open-space test and passive avoidance learning test, cornu Ammonis (CA) 1, CA3, and Purkinje neuron counts, and the brain levels of brain-derived neurotrophic factor and postsynaptic density protein-95. However, G-CSF treatment reduced the glial fibrillary acidic protein immunostaining index and brain levels of malondialdehyde, tumor necrosis factor-alpha, nuclear factor kappa-B, and lactate. In addition, on MR spectroscopy, G-CSF had a reversible effect on brain lactate levels. Conclusion : In this first designed brain irradiation animal model, which evaluated G-CSF effects, we observed that G-CSF had reparative, neuroprotective and anti-neurodegenerative effects and had increased neurotrophic factor expression, neuronal counts, and morphology changes. In addition, G-CSF had a proven lactate-lowering effect in MR spectroscopy and brain materials.

• Korean Journal of Mineralogy and Petrology
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• v.36 no.1
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• pp.19-32
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• 2023

This study was conducted to remove fluorine (F) (initial concentration of 9.5 mg/L) from leachate of reclaimed mine waste dump site via different methods: (1) co-precipitation using Ca-based materials; (2) adsorption using activated carbon and fly ash; and (3) coagulation and sedimentation using alum. The F removal efficiencies of each case were estimated as 65.6% (Ca co-precipitation), 27.9% (adsorption of activated carbon), 71.5% (adsorption of fly ash), and 96.6% (alum coagulation and sedimentation). In addition, the applicability of the continuous treatment process using alum coagulation was evaluated by lab-scale experiments using simulated mine drainage containing F of lower (6.4 mg/L) and higher (15.7 mg/L) concentrations, and it was confirmed that the treatment of both cases met the domestic standard (below 3 mg/L) for discharged water in clean areas. Furthermore, the results of bench-scale field tests indicated that the water quality standard of discharged water could be satisfied with the proper operation and management of the process.

• Journal of the Korean Geotechnical Society
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• v.26 no.6
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• pp.29-38
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• 2010

Micro-piles have been used to increase the bearing capacity or to restrain settlement of existing shallow foundation. Recently, micro-piles are used to support the shallow foundation, to stabilize the slope and to resist the sliding of retaining wall. Using the micro-piles in geotechnical engineering, some investigators have studied the effective installing method by model test or field test. But most of previous studies are chiefly focused on the micro-piles in sand or clay layer. If a rock layer exists in soil, the installing length of micro-piles may be determined by the depth of rock layer. In this case, the stiffness of pile may be changed by the installing length of pile, and so the installing method has to be altered by the changed stiffness of pile. Model tests have been conducted to study the installation method of micro-pile in soil with rock layer. As a result, when the ratio of length of pile is below 50 ($L/d{\leq}50$), installing of micro-piles in vertical position is effective regardless of the depth of rock layer. If the depth of rock layer is deeper than soil failure zone and the ratio of the length of pile exceeds 50 (L/d>50), installing of the micro-piles in sloped position is effective.