• The Journal of Internal Korean Medicine
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• v.44 no.2
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• pp.138-145
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• 2023

Objective: This study identified the effects of Korean medicine treatment on a patient with metabolic dysfunction-associated fatty liver disease (MAFLD). Methods: A 43-year-old man with MAFLD was treated with Saenggangunbi-tang with regular exercise from August 13, 2022, to December 24, 2022, to reduce fatigue and dyspepsia and to improve laboratory findings, such as liver enzymes and lipid profiles. We observed changes in symptoms and laboratory findings during the approximately four-month treatment. Results: Treatment with Saenggangunbi-tang resulted in decreased serum levels of liver enzymes, triglycerides, hepatic steatosis index scores, and clinical symptoms. During the treatment, the patient performed regular exercise; however, there was no significant change in body weight until the end of the study. Conclusion: This study suggests the availability of Saenggangunbi-tang as a therapeutic option for managing MAFLD patients.

• Korean Journal of Acupuncture
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• v.40 no.2
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• pp.44-53
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• 2023

Objectives : This study was conducted to reveal the relationship between multiple factors of traditional Korean Medicine diagnosis and consider the further probabilities of treating people with physical and mental problems not defined as diseases, which is called 'Mibyeong' in traditional Korean Medicine. Methods : 40 healthy participants were included in the observational clinical trial. The participants were asked to complete health questionnaires (e.g. State-Trait Anxiety Inventory, Pittsburgh Sleep Quality Index, Stress Response Inventory) and they went through a traditional diagnosis process, including four stages of diagnosis (looking, listening/smelling, inquiring, and pulse taking), by a Korean Medicine doctor. Both the Korean Medicine doctor and an artery tonometry device performed the pulse diagnosis. Results : Although all participants were healthy people with no history of disease, more than half of participants had a problem related with severe level of fatigue (n=19), sleep disturbance (n=26) and stress (n=27) status according to the related questionnaires. Participants diagnosed with phlegm syndrome by the Korean Medicine doctor showed significantly greater score in phlegm pattern questionnaires than participants who were not. However, there was little agreement between the doctor's pulse diagnosis and radial artery tonometry results. Conclusions : We conducted a pulse diagnosis and measured health-related information along with the traditional Korean Medicine diagnose procedure, including four stages of diagnosis, and we found a linkage between diagnosis of phlegm and the phlegm pattern questionnaire score. The results suggest that a number of healthy participants, with no disease diagnosed, have Mibyoung symptoms which need further clinical management. Thus, we suggest that Mibyoung management programs based on qualified diagnosis tools and traditional Korean medicine diagnosis procedures be developed, and that future research using various diagnostic tools be carried out on a large population.

• Advances in concrete construction
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• v.17 no.3
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• pp.151-158
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• 2024

The calculation of the natural frequencies versus Young's modulus of carbon nanotubes with modified continuum shell is the subject of current research. When designing these tubes, it is important to understand their frequencies because excessive vibrations might cause fatigue. These tubes are designed and built to meet specific needs and have been suitably modified to investigate their vibratory response. There are numerous uses for carbon nanotube free vibration analysis in the mechanical sciences. The fundamental frequency with Young's modulus for clamped-free and simply supported end conditions, which is connected to the carbon nanotubes, is calculated theoretically for chiral single carbon nanotubes. When Young's modulus rises, so does the frequency curve pattern. Young's modulus influences the single-walled carbon nanotube's dynamic response by simulating it as a modified continuum shell. The Young's modulus of chiral tube and the value of frequency increased as the chiral tube's index increased. The results are checked against past studies to ensure the problem's validity and are determined to be accurate.

• International Journal of Highway Engineering
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• v.10 no.2
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• pp.1-13
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• 2008

This study presents a case study of condition evaluation of various asphalt pavement sections to estimate performance lives. The pavement surface conditions including cracking and rutting are first evaluated using a automatic pavement analyzer, ARAN. HPCI(Highway Pavement Condition Index) values are estimated using the pavement surface distress data. It is observed from the pavement distress survey that the major distress type of the sections is top-down cracking. The modulus value of each pavement layer is back-calculated from the defection data obtained from a FWD(Falling Weight Deflectometer) and compared with the laboratory measured dynamic modulus values. Remaining lives of the various pavement sections are estimated based on a mechanistic-empirical approach and AAHTO 1993 design guide. The structural capacities of the all pavement sections based on the two approaches are strong enough to maintain the pavement sections for the rest of design life. Since the major distress type is top-down cracking, the remaining lives of the pavement sections are estimated based on HPCI and existing performance database of highway pavements. To evaluate the causes of premature pavement distress, various material properties, such as air void, asphalt binder content, aggregate gradation, dynamic modulus and fatigue resistance, are measured from the field cores. It is impossible to accurately estimate the binder contents of field samples using the ignition method. It is concluded from the laboratory tests that the premature top down cracking is mainly due to insufficient compaction and inadequate aggregate gradation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.1
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• pp.615-621
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• 2018

To enhance the energy saving and comfort of indoors, this study performed a stimulation of sound fluctuation, color temperature, and aroma. The experiment with EEG, HRV, and Vibra images was conducted in an environmental test room with a temperature of $25[^{\circ}C]$, relative humidity of 50[RH%], air current speed of 0.002[m/s], and illuminance of 1000[lux]. The stimulation experiment set up different sensory stimulation conditions, such as before exposure, single-sensory stimulation of fluctuation a=1.106 jazz music, single-sensory stimulation of RED color lighting, single-sensory stimulation of scent aroma, and multi-sensory stimulation of fluctuation a=1.106 jazz music, RED color lighting, and scent aroma. After the multi-sensory stimulation of fluctuation a=1.106 jazz music, RED color lighting and scent aroma, the capacity for work and attention were increased, and the stress index and fatigue degree were decreased. In addition, multi-sensory stimulation of fluctuation a=1.106 jazz music, RED color lighting, and scent aroma were effective in maintaining a stable heart and health. In addition, the Vibra image appeared to decrease tension/anxiety and stress. The multi-sensory stimulation of fluctuation a=1.106 jazz music, RED color lighting, and scent aroma help increase the Neuro-energy more than that by no exposure and single-sensory stimulation.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.6
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• pp.903-910
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• 2016

In this study, the expression level of estrogen receptor in an ovariectomized rat model was effectively enhanced by MS-10, Cirsium japonicum and Thymus vulgaris extract complex, in a reversible manner. MS-10 plays a positive role in enhancing estrogen activity at low concentrations, leading to improved women's health. In order to determine whether or not MS-10 improves menopausal symptoms clinically, a randomized, double-blinded, and placebo-controlled clinical study was carried out on 62 middle-aged women treated with 500 mg of MS-10 or placebo daily for 12 weeks. Clinical menopausal symptoms were evaluated by Kupperman's index (KI) detecting various menopausal symptoms, including hot flushes, parenthesis, insomnia, nervousness, melancholia, dizziness, fatigue, rheumatic pain, palpitations, formication, and headaches. Total KI score decreased significantly by about 18% upon ingestion of MS-10. Colpoxerosis, a main symptom of menopause, was significantly reduced by about 21% upon ingestion of MS-10 in contrast to placebo. In addition, reduction of insulin-like growth factor-1 with age was improved by over 10% upon ingestion of MS-10, whereas there were no significant difference with placebo. No side effects appeared after treatment with MS-10. Thus, MS-10 can be suggested as a plausible natural substance for improving women's health.

• International Journal of Highway Engineering
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• v.12 no.2
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• pp.99-106
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• 2010

Until now, the thickness design of anti-freezing layer has been empirically conducted using the frost depth determined from the freezing index. This approach cannot consider the structural properties of anti-freezing layer, which can cause the over-design of pavement structure. This paper presents results of structural evaluation of anti-freezing layer using the Falling Weight Deflectormeter (FWD) deflections. The FWD testing was directly conducted on top of the subbase layer located at the embankment, cutting, and boundary area of each section. It is observed from this testing that the center deflections of pavement structure with anti-freezing layer are smaller than those without anti-freezing layer. The deflection reduction rates are 15~55% in the embankment, 11~64% in the cutting, and 2~38% in the boundary, respectively. It was also found that the use of antifree zing layer enables to reduce the Surface Curvature Index (SCI) values up to 24 percent. Fatigue lives show that pavement structure with antifreezing layer are about two times higher than the those without anti-freezing layer. This fact indicates that the anti-freezing layer should be considered as a structural layer in the asphalt pavement system.

• Journal of the Korean Society of School Health
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• v.6 no.1
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• pp.69-77
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• 1993

The purpose of this study is to obtain some basic data necessary for more effective health education by questionnaire survey on the knowledge, attitude and preventive health behavior. The questionnaire forms were delivered to 500 university students in seoul during periods from 24 to 28, september, from 7 to 19, October, 1991. The result of this study can be summarized as follows: 1) Washing hands after using toilet has relationship to sex (fece: $X^2=51.55$, urine: $X^2=36.25$, p<0.05). Index of female was higher than that of male. 2) Tooth brushing has relationship to sex ($X^2=13.28$, p<0.05). The tendency of practice of male and female was similar. 3) Changing of underwear 1~3 days were the highest and it has relationship to sex ($X^2=162.846$, p<0.05), birth place ($X^2=97.18$, p<0.05). Index of female was higher than that of male. 4) Bathing has relationship to sex ($X^2=80.92$, p<0.05). birth place ($X^2=54.18$, p<0.05, pocket money ($X^2=33.04$, p<0.05). 5) The attitude on occurrence of epidemic disease has relationship to sex ($X^2=70.33$, p<0.05). A female was more senstive than male. 6) In case of slight disease, a cold, illness from fatigue, the utilization of drug store was higher. The utilization of medical center according to disease has relationship to sex ($X^2=69.84$, p<0.05). 7) Medical behaviorism has relationship to school year ($X^2=35.18$, p<0.05), sex ($X^2=42.18$, p<0.05). 8) The utilization of school health center has relationship to sex ($X^2=10.73$, p<0.05), the school year ($X^2=72.09$, p<0.05), the pocket money ($X^2=38.80$, p<0.05). 9) The experience of health education has relationship to school year ($X^2=10.96$, p<0.05). No experence is 95.4%. 10) The subject for health-medical knowledge is necessary. The need for subject has relationship to sex ($X^2=10.86$, p<0.05).

• Annals of Clinical Neurophysiology
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• v.17 no.2
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• pp.61-67
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• 2015

Background: The aim of this study was to investigate the predictive value of snoring frequency in the diagnosis and severity of obstructive sleep apnea. Methods: Patients who underwent polysomnography with one or more of the following characteristics were included: 1) sleepiness, non-restorative sleep, fatigue, or insomnia symptoms; 2) arousal due to cessation of breathing or the occurrence of gasping or choking when waking up; and 3) habitual snoring, breathing interruptions, or both, noted by a bed partner or other observer. We analyzed the differences in clinical and polysomnographic variables between patients with and without obstructive sleep apnea and investigated the associations of those variables with obstructive sleep apnea severity. Results: One hundred ninety-three patients met the inclusion criteria, and 145 of the 193 patients were diagnosed with obstructive sleep apnea. Multiple logistic regression analysis showed that large neck circumference (p = 0.0054) and high snoring index (p = 0.0119) were independent predictors for obstructive sleep apnea. Moreover, between the obstructive sleep apnea severity groups, there was a strong tendency of difference in body mass index (p = 0.0441) and neck circumference (p = 0.0846). However, there was no significant difference in snoring frequency according to obstructive sleep apnea severity (p = 0.4914). Conclusions: We confirmed that snoring frequency is a predictor of obstructive sleep apnea. In addition, we showed for the first time that snoring frequency is not associated with obstructive sleep apnea severity, thus it is not a valuable marker for predicting obstructive sleep apnea severity.

• Journal of Korean Society of Transportation
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• v.34 no.4
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• pp.341-353
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• 2016

Highway is mainly in charge of middle-long distance of vehicular travel. Trip length has shown a growing trend due to increased commute distances by the relocation of public agencies. For this reason, the proportion of driver-driven accidents, caused by their fatigue or sleepiness, are very high on highways. However, existing studies related to accident prediction have mainly considered external factors, such as road conditions, environmental factors and vehicle factors, without driving behavior. In this study, we suggested an accident index (FDR, Fatigued Driving Rate) based on traffic behavior using large-scale Car Navigation path data, and exlpored the relationship between FDR and traffic accidents. As a result, FDR and traffic accidents showed a high correlation. This confirmed the need for a paradigm shift (from facilities to travel behavior) in traffic accident prediction studies. FDR proposed in this study will be utilized in a variety of fields. For example, in providing information to prevent traffic accidents (sleepiness, reckless driving, etc) in advance, utilization of core technologies in highway safety diagnostics, selection of priority location of rest areas and shelter, and selection of attraction methods (rumble strips, grooving) for attention for fatigued sections.