• Title/Summary/Keyword: fatigue effect

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Traditional Korean Medicine for Non-Small Cell Lung Cancer Patient Undergoing Pembrolizumab Immunotherapy: A Case Report (Pembrolizumab 면역치료를 시행 중인 비소세포성 폐암환자의 한방치료 증례보고)

  • Shim, So-hyun;Seo, Hee-jeong;Seo, Hyung-bum;Cho, Im-hak;Lee, Chan;Kim, So-yeon;Han, Chang-woo;Park, Seong-ha;Yun, Young-ju;Lee, In;Kwon, Jung-nam;Hong, Jin-woo;Choi, Jun-yong
    • The Journal of Internal Korean Medicine
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    • v.40 no.4
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    • pp.709-722
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    • 2019
  • Objective: The purpose of this study was to report the effect of traditional Korean medicine (TKM) in alleviating the side effects of lung cancer patient undergoing immunotherapy. Method: A 43-year-old man, who was diagnosed with non-small cell lung cancer, received pembrolizumab treatments. The patient was treated with acupuncture and herbal medicine (Geoeoyangpye-tang) to control various uncomfortable symptoms. The degree of pain was measured by the numeric rating scale (NRS). The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Core 30 (EORTC QLQ-C30) and the EORTC 13-item lung cancer-specific module (EORTC LC-13 questionnaire) were used to assess the change in the quality of life. Results: After the TKM treatment, the flank pain and arthralgia based on the NRS were significantly improved. Various uncomfortable symptoms such as fatigue, dyspnea, insomnia, and loss of appetite were also significantly improved, based on the EORTC QLQ-C30 and EORTC QLQ-LC13. The size of the primary tumor was decreased during treatment. The disease status was stable radiologically after two months from discharge.

Analysis on the Changes in Muscle Function of the Leg Joint in Athletics Athletes Through by Whole Body Vibration Exercise Training (전신진동(Whole body vibration)운동훈련을 통한 육상 투척선수의 하지관절 근육 기능변화에 관한 분석)

  • Lee, Youngsun;Yoon, Changsun;Han, KiHoon;Kim, Jinhyun;Hah, Chongku;Park, Joonsung;Kim, Jongbin
    • Journal of Convergence for Information Technology
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    • v.11 no.3
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    • pp.250-260
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    • 2021
  • The purpose of this study is to investigate muscle function and symmetry index during whole body vibration exercise using lower extremity training posture for throwing athletes. For throwing athletes in their 20s(6 males, 4 females, age: 24.60±0.92years, height: 177.90±7.40cm, weight: 92.90±22.97kg), lower extremity training postures with squat, carphrase, and lunge movements. Whole body vibration exercise training was performed using. Tensiomyography(TMG) variables Time Delay(Td), Time Contraction(Tc), Time Sustain(Ts) Time Relaxation(Tr), and Displacement Maximumal(Dm) in the lower extremity joint muscles(biceps femoris(BF), gastrocnemius lateral(GL), gastrocnemius medial(GM), rectus femoris(RF), tibialis anterior(TA), lateral vastus(LV), medial latissimus(ML)), were measured to compare and analyze muscle activity, muscle fatigue, and left-right symmetry. The results of the study are left RF, VL, right VM (p<.05) in Td, VM (p<.05) in Tc, GM in Ts (p<.05), left RF in Tr, and right TA (p<. 05) showed a change. Therefore, it has been proven that various whole-body vibration training is an effective exercise with changes in muscle contraction, and stability of the core is secured by symmetry of the left and right muscles. For this reason, the whole body vibration exercise will have a positive effect on rehabilitation training, and it is believed that it will be able to improve performance.

The Effects of Different Surface Level on Muscle activity of the Upper Body and Exercise Intensity during Mountain Climbing Exercise (지면에서의 마운틴 클라이밍 운동 시 상체의 위치 변화가 운동 강도와 근활성도에 미치는 영향)

  • Park, Jun-Ho;Jung, Jae-Hu;Kim, Jong-Geun;Chae, Woen-Sik
    • Korean Journal of Applied Biomechanics
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    • v.31 no.1
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    • pp.72-78
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    • 2021
  • Objective: The purpose of this study was to investigate relations and effectiveness about mountain climbling exercise with different level of support surfaces by analyzing heart rate and EMG data. A total of 10 male college students with no musculoskeltal disorder were recruited for this study. Method: The biomechanical analysis was performed using heart rate monitor (Polar V800, Polar Electro Oy, Finland), step-box, exercise mat, and EMG device (QEMG8, Laxtha Inc. Korea, sampling frequency = 1,024 Hz, gain = 1,000, input impedance > 1012 Ω, CMRR > 100 dB). In this research, step-box were used to create different surface levels on the upper body (flat surface, 10% of subject's height, 20% of subject's height, and 30% of subject's hight). Based on these different conditions, data was collected by performing mountain climbing exercise during 30 seconds. Subjects were given 5 minutes of break to prevent muscular fatigue after each exercise. For each dependent variable, a one-way analysis of variance with repeated measures was conducted to find significant differences and Bonferroni post-hoc test was performed. Results: The results of this study showed that exercise intensity was reduced statistically as increased surface level on the upper body. Muscle activity of the upper rectus abdominis and biceps femoris for 30% of surface level was significantly higher than the corresponding values for flat surface. However, the opposite was found in the rectus femoris. In general, muscle activity of the lower rectus abdominis, erector spinae, external oblique abdominis, and gluteus maximus increased when surface level increased, but the differences were not significant. Conclusion: As a result, the increase in surface level of the body would change muscle activity of the upper body, indicating that different surface level of the upper body may cause significant effect on particular muscles to be more active during mountain climbing exercise. Based on results of this study, it is suggested to set up an appropriate surface level to target particular muscle to expect an effective training. It is also important to set adequate surface levels to create an effective training condition for preventing exercise injuries.

Development and Effects of Health Promotion Education Program for the Auxiliary Police - Based on the PRECEDE-PROCEED Model - (PRECEDE-PROCEED 모형을 적용한 의무경찰의 건강증진교육프로그램의 개발 및 효과)

  • Kim, Young-jin
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.1
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    • pp.115-131
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    • 2022
  • The purpose of this study was to develop and examine the effect of the Health Promotion Education Program for the Auxiliary Police based on the PRECEDE-PROCEED Model. This study was conducted using a nonequivalent control group pretest-posttest design. Twenty-five participants were selected by convenience sampling method and assigned to the experimental group, and 26 participants were assigned to the control group. The data were collected from Auxiliary Police officer in D provincial Police Agency. All of participations completed questionnaires about self-efficacy, social support, availability of resources, health promotion behavior, quality of life and received the objective stress test. In addition, the experimental group completed 7 sessions of health promotion Education programs according to PRECEDE-PROCEED model for 5 weeks. Data were analyzed using the SPSS/WIN 21.0 Program. There was significant differences over time between the groups in terms of health promotion behavior (F=7.63, p<.001), autonomic nervous activity (F=29.24, p<.001), stress resistance (F=31.22, p<.001), stress index (F=22.42, p<.001), fatigue (F=12.87, p<.001), and quality of life (F=3.49, p=.042). The results may be crucial to develop strategy in order to decrease the disease prevalence as well as increase the participants' overall quality of life. As a result, the Health Promotion Education Program for the auxiliary police was proved to be an effective intervention in order to improve the quality of life. Therefore, the program may be a useful intervention for the auxiliary police.

A Study on the Design of Planterior to Reduce and Purify Indoor Particle Matters (PM) (실내 미세먼지 저감을 위한 플랜테리어 디자인 연구)

  • Ahn, SeungWon;Jeong, Jun Hyun
    • Journal of the Korean Society of Floral Art and Design
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    • no.44
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    • pp.3-31
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    • 2021
  • To verify the types of effects that plants have in our general living conditions, I examined an air quality in living rooms of the three, 129.78m2 size, apartments that were with and without plants. and the findings of the study were as addressed below. 1) Experiments showed no statistically significant differences in Case A. However, in Case B and Case C, the standard deviation of PM10, PM2.5 and PM 1.0 verified that each had statistically significant (p<.01) differences. 2) It is believed that the effect of reducing particle matters due to the installation of plants in the indoor space is to vary significantly depending on the indoor environmental conditions, the cleanliness of the room, and the amount of furniture and may also differ depending on the daily dietary cooking method. In addition, it is believed that the planterior will not only reduce indoor fine dust, but also reduce the psychological comfort and eye fatigue of the residents. Nevertheless, supplementary research is needed. 3) In the planterior design for reducing indoor particle matters, various measures were examined. Among them, the vertical wall design method was tested and suggested through empirical experiments. In addition, maintenance methods were proposed depending on the type of indoor plant.

Effect of Non-contact Korean Medical Treatment for Patients Recovering at Home with Positive Coronavirus Disease 2019 Diagnostic Test Results at a Local Public Health Center: A Retrospective Chart Review (지역 보건소에서 시행한 코로나 바이러스 감염증-19 진단 검사상 양성인 재택치료 환자의 비대면 한의진료 효과: 후향적 차트 리뷰)

  • Jeon, Chaeheun;Choi, Daejun;Kim, Gyeongmuk;Kim, Hyejin;Leem, Jungtae;Chi, Gyoo-yong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.36 no.4
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    • pp.130-137
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    • 2022
  • Due to the coronavirus disease 2019 (COVID-19) pandemic, appropriate management of sequelae and treatment of infectious symptoms became increasingly important healthcare issues. Although the practice guidelines and treatment cases based on the East Asian traditional medicine have been reported, there are rare studies on the use of Korean medicine in Korea. Therefore, this study aimed to present the progress of non-contact Korean medical treatment for infected patients at a local public health center using retrospective chart review. A total of 18 patients were prescribed with 5 days of herbal decoction and medicine extract covered by the national health insurance. With the questionnaire form, the progression and improvement of symptoms before and after treatment were evaluated using the numerical rating scale (NRS), and the treatment satisfaction and opinions were obtained. The symptoms such as cough (5.56±2.23 to 2.89±2.14), sputum (6.11±1,75 to 3.28±2.47), sore throat (6.06±2.70 to 1.47±1.62), anorexia (5.56±2.63 to 1.94±2.21), nausea (3.75±1.71 to 1.17±1.11), diarrhea (3.40±2.63 to 1.50±1.51), chest tightness (4.93±2.46 to 2.29±2.30) and fatigue (6.44±1.79 to 2.67±1.88) all improved according to the NRS, and the satisfaction with herbal medicine treatment on a 5-point Likert scale was 4.24±0.90. No side effects and adverse reactions were reported. Thereupon non-contact Korean medical treatment can be concluded that it effectively reduces the COVID-19 infection mild symptoms in restrictive extent. Since the retrospective data does not include a control group, the more confirmative data is needed by multicenter and large-scale controlled clinical study afterwards.

Experimental Analysis of Large Size Concrete-Filled Glass Fiber Reinforced Composite Piles Subjected to the Flexural Compression (대구경 콘크리트 충전 복합소재 파일의 휨-압축 거동에 대한 실험적 분석)

  • Lee, Sung Woo;Choi, Sokhwan
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.5A
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    • pp.519-529
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    • 2009
  • Fiber reinforced composite materials have various advantages in mechanical and chemical aspects. Not only high fatigue and chemical resistance, but also high specific strength and stiffness are attained, and therefore, damping characteristics are beneficial to marine piles. Since piles used for marine structures are subjected to compression and bending as well, detailed research is necessary. Current study examine the mechanical behavior under flexural and/or compressive loads using concrete filled fiber reinforced plastic composite piles, which include large size diameter. 25 pile specimens which have various size of diameters and lengths were fabricated using hand lay-up or filament winding method to see the effect of fabrication method. The inner diameters of test specimens ranged from 165 mm to 600 mm, and the lengths of test specimens ranged from 1,350 mm to 8,000 mm. The strengths of the fill-in concrete were 27 and 40 MPa. Fiber volumes used in circumferential and axial directions are varied in order to see the difference. For some tubes, spiral inner grooves were fabricated to reduce shear deformation between concrete and tube. It was observed that the piles made using filament winding method showed higher flexural stiffness than those made using hand lay-up. The flexural stiffness of piles decreases from the early loading stage, and this phenomenon does not disappear even when the inner spiral grooves were introduced. It means that the relative shear deformation between the concrete and tube wasn't able to be removed.

Effect of Heat Stress of Extreme Heat Lever on Muscle functionand Muscle Injury Markers in Elderly Women (열 스트레스가 여성노인들의 근기능 및 근손상에 미치는 영향)

  • Park, Sok;Lee, Chone Ho;Back, Seung Ok;Shin, Yong Up;Kim, Jung Suk;Cho, Young Wung;Lee, Young Jun
    • 한국노년학
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    • v.30 no.3
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    • pp.793-802
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    • 2010
  • The purpose of this study was to examine the influence of extreme heat on muscle function and muscle injury marker in elderly women. The subjects of this study were eight post-menopausal elderly women without any metabolic disease. All eight subjects were asked to perform the knee joint isokinetic exercise using isokinetic equipment (cybex) in the laboratory and experimental temperature within laboratory was adjusted to two conditions: extreme heat temperature(33±0.5℃) and normal temperature(20±0.5℃) maintained in 50±3% humidity conditions. Each experimental exercise was monitored and analyzed the change of HSP70, LDH and CK. Muscular functions (peak torque, total work, percentage of peak torque body weight, fatigue index, average power and total work) were significant differences at exercise between temperatural conditions (p<.05). In extreme heat temperature, muscular injury markers (HSP70, LDH and CK) were increased, threfore resulted in significantly higher than normal temperature(p<.05). These results show that extreme heat temperature can decrease muscle function in elderly women.

Comparison of Thickness, Tension, and Activation of the Scm and Upper Trapezius Muscles According To The Pillow Height (베개 높이에 따른 SCM과 Upper trapezius의 근 두께, 근 긴장도, 근 활성화 측정비교)

  • Eun-mi Kim;Min-gi Park;Eun-joung Yu;Dongyeop Lee;Ji-Heon Hong;Jae-Ho Yu;Jin-Seop Kim;Yeon Gyo Nam;Seong-Gil Kim
    • Journal of the Korean Society of Physical Medicine
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    • v.19 no.1
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    • pp.53-60
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    • 2024
  • PURPOSE: The study aimed to analyze the effect of pillow height on upper trapezius and sternocleidomastoid (SCM) muscle activity and overall human body comfort to determine the optimal pillow height. METHODS: The study included 32 healthy college students, of both genders, who provided prior consent. It examined three pillow heights (flat, 6cm, 12cm) and measured the upper trapezius and SCM muscles using ultrasonography, myotone, and electromyography(EMG). Muscle activation, thickness, and fatigue were assessed. RESULTS: The study found significant differences in muscle thickness and muscle tone based on the pillow heights (flat, 6cm, and 12cm) with a p < .05. The SCM and upper trapezius muscles were thinnest at a pillow height of 6cm. Muscle tone in the SCM was lower at both 6cm and 12cm pillow heights. Post-hoc measurements showed significant differences in both the SCM and upper trapezius muscles thickness at the 6cm pillow height (p < .05). Also, significant differences in muscle tone were observed only in the SCM, particularly between the 6cm and 12cm pillow heights. CONCLUSION: The ultrasonography and myotone measurements showed a significant difference in muscle thickness and muscle tension, both of which were above 6cm, while there was no difference in muscle activation. Based on the strong correlation between muscle tension and muscle thickness with pillow height, this study concluded that the human body feels comfortable with a 6cm pillow height. Therefore, it is recommended to use a pillow height of 6cm when lying in a supine position.

Induced Prism by the Categories of Spectacle Frames (안경테 종류에 따른 유발프리즘)

  • Park, Woo-Jung;Kim, Soo Woon;Hwang, Hae-Young;Yu, Dong-Sik;Son, Jeong-Sik
    • Journal of Korean Ophthalmic Optics Society
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    • v.17 no.3
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    • pp.311-319
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    • 2012
  • Purpose: One of the critical aspects on dispensing glasses is to match the center of pupils to the optical center of lenses as the mismatched glasses are able to induce uncomfortable effects called prism which has been known to induce phoria, a main cause for asthenopia in many cases. Therefore, we investigated the induced prism occurred by mismatching centers between the center of pupils and the optical center of lenses. Methods: In this study, total 103 subjects were examined whether the center of pupils and the optical center of lenses are matched in horizontal and vertical directions, and then, the data was categorized into 4 groups based on the structural components of glasses. Total amount of prism was compared to show the effect of the glasses frame on the prism induction, and the value of measured prism was compared with the German RAL-RG 915 regulations. Results: The results in respect to the horizontal component showed that the induced prism was not found in 10.7% of total subjects. 73.8% of total subjects were influenced by induced prism, the range of prism was in a tolerance level. However, the 15.5% of total subjects seemed to be influenced by prism which is out of the criterion of tolerance. In case of vertical component, 23.3% of total subjects showed no effects of prism while early adopting glasses, 54.4% of total subjects showed a little prism effect within the criterion of tolerance, and 22.3% of total subjects showed the prism effect out of the tolerance range. This data indicates that group A and B that are less likely adjustable by fitting induce more prism than group C and D in horizontal and vertical components. Conclusions: In higher refractive error condition, it was found that aligning the optical center of lenses with the center of pupils by pre-fitting of glasses frame minimized prism induction in horizontal and vertical components, which ameliorates ocular fatigue. Therefore, appropriate optometric dispensing through fitting by opticians and precise design about monocular PD and monocular Oh are necessary to improve visual perception.