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Effect of Non-contact Korean Medical Treatment for Patients Recovering at Home with Positive Coronavirus Disease 2019 Diagnostic Test Results at a Local Public Health Center: A Retrospective Chart Review

지역 보건소에서 시행한 코로나 바이러스 감염증-19 진단 검사상 양성인 재택치료 환자의 비대면 한의진료 효과: 후향적 차트 리뷰

  • Jeon, Chaeheun (Geumsan Public Health Center) ;
  • Choi, Daejun (Geumsan Public Health Center) ;
  • Kim, Gyeongmuk (Geumsan Public Health Center) ;
  • Kim, Hyejin (Department of Pediatrics of Korean Medicine, Graduate school, Dongshin University) ;
  • Leem, Jungtae (College of Korean Medicine, Wonkwang University) ;
  • Chi, Gyoo-yong (Department of Pathology & Externally contracted diseases, College of Korean Medicine, Dongeui University)
  • 전채헌 (금산군 보건소) ;
  • 최대준 (금산군 보건소) ;
  • 김경묵 (금산군 보건소) ;
  • 김혜진 (동신대학교 대학원 한방소아과) ;
  • 임정태 (원광대학교 한의과대학) ;
  • 지규용 (동의대학교 한의학과 병리외감병학교실)
  • Received : 2022.07.11
  • Accepted : 2022.08.30
  • Published : 2022.08.25

Abstract

Due to the coronavirus disease 2019 (COVID-19) pandemic, appropriate management of sequelae and treatment of infectious symptoms became increasingly important healthcare issues. Although the practice guidelines and treatment cases based on the East Asian traditional medicine have been reported, there are rare studies on the use of Korean medicine in Korea. Therefore, this study aimed to present the progress of non-contact Korean medical treatment for infected patients at a local public health center using retrospective chart review. A total of 18 patients were prescribed with 5 days of herbal decoction and medicine extract covered by the national health insurance. With the questionnaire form, the progression and improvement of symptoms before and after treatment were evaluated using the numerical rating scale (NRS), and the treatment satisfaction and opinions were obtained. The symptoms such as cough (5.56±2.23 to 2.89±2.14), sputum (6.11±1,75 to 3.28±2.47), sore throat (6.06±2.70 to 1.47±1.62), anorexia (5.56±2.63 to 1.94±2.21), nausea (3.75±1.71 to 1.17±1.11), diarrhea (3.40±2.63 to 1.50±1.51), chest tightness (4.93±2.46 to 2.29±2.30) and fatigue (6.44±1.79 to 2.67±1.88) all improved according to the NRS, and the satisfaction with herbal medicine treatment on a 5-point Likert scale was 4.24±0.90. No side effects and adverse reactions were reported. Thereupon non-contact Korean medical treatment can be concluded that it effectively reduces the COVID-19 infection mild symptoms in restrictive extent. Since the retrospective data does not include a control group, the more confirmative data is needed by multicenter and large-scale controlled clinical study afterwards.

Keywords

Acknowledgement

보건사업에 행정적 지원과 격려를 해주신 이종규 부군수님과 이화영 보건소장님을 비롯한 금산군 보건소 공무원분들께 진심으로 감사드립니다. 이 논문은 2022학년도 원광대학교의 교비지원에 의해 수행됨.

References

  1. Yang M, Shang Y, Tian Z, Xiong M, Lu C, Jiang Y, et al. Characteristics of registered studies for Coronavirus disease 2019 (COVID-19): A systematic review. Integr Med Res. 2020 Sep;9(3):100426. https://doi.org/10.1016/j.imr.2020.100426
  2. Korea Centers for Disease Control and Prevention. Updates on COVID-19 in Republic of Korea. 2022 Jul 1;
  3. Lee K, Jeong S, Jeong M, Choi Y, Song M, Jang I. Review on Herbal Medicine Treatment for Late Complications of COVID-19 Patients. J Korean Orient Intern Med. 2021;42(1):53-66. https://doi.org/10.22246/jikm.2021.42.1.53
  4. Raveendran A, Jayadevan R, Sashidharan S. Long COVID: An overview. Diabetes Metab Syndr. 2021 Jun;15(3):869-75. https://doi.org/10.1016/j.dsx.2021.04.007
  5. Lee S, Park J, Lee Y, Kim S, Lee J. A Case Report of Taeeumin with Post COVID-19 Syndrome. J Sasang Const Med. 2021;33(4):32-42. https://doi.org/10.7730/JSCM.2021.33.4.32
  6. Angelo C, Roberto B, Francesco L, Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent Symptoms in Patients After Acute COVID-19. JAMA. 2020 Aug 11;324(6):603-5. https://doi.org/10.1001/jama.2020.12603
  7. Dai T, Zhang L, Dai X, Zhang X, Lu B, Zheng Y, et al. Multimode participation of traditional Chinese medicine in the treatment of COVID-19. Integr Med Res. 2021;10:100781. https://doi.org/10.1016/j.imr.2021.100781
  8. Lu C, Zheng R, Xue X, Zhang X, Liu X, Jin X, et al. Traditional Chinese medicine for COVID-19 pandemic and emerging challenges: An online cross-sectional survey in China. Integr Med Res. 2021;10:100798. https://doi.org/10.1016/j.imr.2021.100798
  9. Byun J, Sunwoo J, Kang K, Kim K, Kim D, Kim D, et al. Consideration for Coronavirus Disease 2019 Drug Treatment in Patients with Epilepsy on Antiepileptic Drugs. J Korean Neurol Assoc. 2022;40(2):121-6. https://doi.org/10.17340/jkna.2022.2.2
  10. Wang F, Kream R, Stefano G. Long-Term Respiratory and Neurological Sequelae of COVID-19. Med Sci Monit Int Med J Exp Clin Res. 2020 Nov 1;26:e928996. https://doi.org/10.12659/MSM.928996
  11. Chi G. Features and Interpretation of Olfactory and Gustatory Disorders in the Corona Virus Disease-19. J Physiol Pathol Korean Med. 2020;34(6):309-18. https://doi.org/10.15188/kjopp.2020.12.34.6.309
  12. Park S, Bang J. A Study on the Three Yin Diseases(三陰病) in the 『Shanghanlun(傷寒論)』 -Focusing on Prognosis Analysis-. J Korean Med Class. 2021;34(1):47-65. https://doi.org/10.14369/jkmc.2021.34.1.047
  13. Kang N, Han J, Ko W, Yoon H. A Study on the Skin Disease of Sanghanron《傷寒論》and Geumgweyoryak《金匱要略》. J Korean Med Ophthalmol. 2012;25(1):55-74. https://doi.org/10.6114/jkood.2012.25.1.055
  14. Kim J, Jeong C, Jang W, Baik Y. A Study on Acupuncture in Shanghanlun(傷寒論). J Korean Med Class. 2015;28(1):127-42. https://doi.org/10.14369/skmc.2015.28.1.127
  15. Park M, Kim Y. Comparative Study on Etiological Cause, Pathogenesis Mechanism of 『Shanghanlun』 and 『Wenbingtiaobian』. J Physiol Pathol Korean Med. 2013;27(1):1-10. https://doi.org/10.15188/kjopp.2013.02.27.1.1
  16. Ang L, Lee H, Choi J, Zhang J, Lee M. Herbal medicine and pattern identification for treating COVID-19: a rapid review of guidelines. Integr Med Res. 2020 Jun;9(2):100407. https://doi.org/10.1016/j.imr.2020.100407
  17. Nabeshima A, Sakamoto A, Iwata K, Kitamura Y, Masui S, Inomata S, et al. Maoto, a traditional herbal medicine, for post-exposure prophylaxis for Japanese healthcare workers exposed to COVID-19: A single center study. J Infect Chemother Off J Jpn Soc Chemother. 2022 Jul;28(7):907-11. https://doi.org/10.1016/j.jiac.2022.03.014
  18. Xiong W, Wang G, Du J, Ai W. Efficacy of herbal medicine (Xuanfei Baidu decoction) combined with conventional drug in treating COVID-19:A pilot randomized clinical trial. Integr Med Res. 2020 Sep;9(3):100489. https://doi.org/10.1016/j.imr.2020.100489
  19. Hu K, Guan W, Bi Y, Zhang W, Li L, Zhang B, et al. Efficacy and safety of Lianhuaqingwen capsules, a repurposed Chinese herb, in patients with coronavirus disease 2019: A multicenter, prospective, randomized controlled trial. Phytomedicine Int J Phytother Phytopharm. 2021 May;85:153242. https://doi.org/10.1016/j.phymed.2020.153242
  20. Yin B, Bi Y, Sun L, Huang J-Z, Zhao J, Yao J, et al. Efficacy of Integrated Traditional Chinese and Western Medicine for Treating COVID-19: A Systematic Review and Meta-Analysis of RCTs. Front Public Health. 2021;9:622707. https://doi.org/10.3389/fpubh.2021.622707
  21. WHO Expert Meeting on Evaluation of Traditional Chinese Medicine in the Treatment of COVID-19. 2022 Mar.
  22. Xiong X, Wang P, Su K, Cho W, Xing Y. Chinese herbal medicine for coronavirus disease 2019: A systematic review and meta-analysis. Pharmacol Res. 2020 Oct;160:105056. https://doi.org/10.1016/j.phrs.2020.105056
  23. Liu M, Gao Y, Yuan Y, Yang K, Shi S, Tian J, et al. Efficacy and safety of herbal medicine (Lianhuaqingwen) for treating COVID-19: A systematic review and meta-analysis. Integr Med Res. 2021 Mar;10(1):100644. https://doi.org/10.1016/j.imr.2020.100644
  24. Liu M, Gao Y, Yuan Y, Yang K, Shi S, Zhang J, et al. Efficacy and Safety of Integrated Traditional Chinese and Western Medicine for Corona Virus Disease 2019 (COVID-19): a systematic review and meta-analysis. Pharmacol Res. 2020 Aug;158:104896. https://doi.org/10.1016/j.phrs.2020.104896
  25. Lee S, Shin J, Lee S. Anti-allergic Effects of Shensuyin. Korean JOrientInt Med. 2005;26(1):119-28.
  26. Kim H, Han H, Jang J, Park E, An T, Seo H, et al. Clinic Study on Herb Medication for Patients Who have a Chronic Respiratory Disease from the Cold Sequelae. KOREAN J Orient Med Prescr. 2010;18(1):181-9.
  27. Chae B. A clinical study of allergic rhinitis. J Korean Orient Med. 2000;21(3):149-65.
  28. Heo J. Donguibogam. Donguibogam chulpansa; 2010. 1072-3, 1261 p.
  29. Gu J, Kim S, Im E, Kim S, Kim J. One Clinical Case Report of Lung Cancer Patient with Depression and Anxiety Disorder Improved by Korean Traditional Medical Treatment and Breathing Meditation. Korean J Orient Physiol Pathol. 2011;25(6):1102-7.
  30. Kim S, Kim J, Park S, Choi J, Cho N. A Case Report of Brown-Sequard Syndrome Caused by Traumatic Cervical Fracture. The Acupuncture. 2015;32(1):133-40. https://doi.org/10.13045/acupunct.2015013
  31. Kim H, Yoo J. Traditional Korea Medicine for Enhanced Recovery after Surgery(ERAS) in Inpatients after Gynecological Surgery : Retrospective Analysis. J Korean Obstet Gynecol. 2019;32(3):142-61. https://doi.org/10.15204/jkobgy.2019.32.3.142
  32. Oh J, Jung E, Choi K, Heo J, Kim H, Ryu J, et al. Korean Medicinal In-patient Treatments for Chronic Renal Disease : 2 cases report. J Physiol Pathol Korean Med. 2016;30(4):289-99. https://doi.org/10.15188/kjopp.2016.08.30.4.289
  33. Jung W, Moon S, Cho K, Kim Y, Bae H, Lee K. The Transient Antifebrile effect of Bangpunghaedok-tang on the incipient fever. J Kyung Hee Univ. 1997;13(4):378-89.
  34. Shin D, Lee J, Kim D. Two Cases of Stroke in Childhood. J Korean Orient Pediatr. 2003;17(1):87-97.
  35. Lee K, Yoon Y, Choi I, Ko S. 5 Cases of Rhinosinusitis Diagnosed and Evaluated by OMU CT. J Korean Med Ophthalmol Otolaryngol Dermatol. 2014;27(3):133-44. https://doi.org/10.6114/JKOOD.2014.27.3.133
  36. Liang C, Hui N, Liu Y, Qiao G, Li J, Tian L, et al. Insights into forsythia honeysuckle (Lianhuaqingwen) capsules: A Chinese herbal medicine repurposed for COVID-19 pandemic. Phytomedicine Plus Int J Phytother Phytopharm. 2021 May;1(2):100027. https://doi.org/10.1016/j.phyplu.2021.100027
  37. Hanuigwadaehak Bonchohak Pyeonchanwiwonhoe. Bonchoh ak. YeongRimSa Publising Co; 2011. 242, 497-8 p.
  38. Arita R, Ono R, Saito N, Takayama S, Namiki T, Ito T, et al. Kakkonto, shosaikoto, Platycodon grandiflorum root, and gypsum (a Japanese original combination drug known as saikatsugekito): Pharmacological review of its activity against viral infections and respiratory inflammatory conditions and a discussion of its applications to COVID-19. Tradit Kampo Med. 2020;7(3):115-27. https://doi.org/10.1002/tkm2.1258
  39. Ji M, Bo A, Yang M, Xu J, Jiang L, Zhou B, et al. The Pharmacological Effects and Health Benefits of Platycodon grandiflorus-A Medicine Food Homology Species. Foods Basel Switz. 2020 Jan 31;9(2):E142. https://doi.org/10.3390/foods9020142
  40. Dong Z, Lu X, Tong X, Dong Y, Tang L, Liu M. Forsythiae Fructus: A Review on its Phytochemistry, Quality Control, Pharmacology and Pharmacokinetics. Mol Basel Switz. 2017 Sep 4;22(9):E1466. https://doi.org/10.3390/molecules22091466