• Title/Summary/Keyword: fast screening

Search Result 131, Processing Time 0.027 seconds

Acoustic Species Identification of Korean Myotis Bats (Chiroptera: Vespertilionidae)

  • Yoon, Kwang Bae;Rahman, M. Mafizur;Park, Yung Chul
    • Journal of Forest and Environmental Science
    • /
    • v.32 no.1
    • /
    • pp.68-73
    • /
    • 2016
  • We investigated structure and intensity of 267 echolocation calls that were collected from the five Korean Myotis species (M. nettereri, M. petax, M. ikonnikovi, M. macrodactylus and M. formosus). All the Myotis species produced typical FM call pattern with similar echolocation call shapes and outer shapes, producing steep, downward frequency-modulated calls. A pulse has two harmonies, which consist of the first harmony with wider bandwidth and the second harmony with narrower bandwidth. The PF of the first harmony is higher than that of the second harmony. The typical FM call structure, with two harmonies and wide bandwidth, might be highly related to fast flying and wide screening in the dense forests. In classification of the echolocation calls by DFA, most of calls from the five species could be well correctly classified. All calls of M. nettereri (100% of 17 calls), M. formosus (95.5% of 22 calls) and M. ikonnikovi (85.7% of 70 calls) could be well discriminated from those of the other species, whereas calls of M. petax and M. macrodactylus could be discriminated by 70.4% of 98 calls and 76.7% of 60 calls, respectively. Our results indicate that the five Korean Myotis species can be well identified by the echolocation calls with high correct classification by DFA.

High Resolution Melting Analysis for Epidermal Growth Factor Receptor Mutations in Formalin-fixed Paraffin-embedded Tissue and Plasma Free DNA from Non-small Cell Lung Cancer Patients

  • Jing, Chang-Wen;Wang, Zhuo;Cao, Hai-Xia;Ma, Rong;Wu, Jian-Zhong
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.11
    • /
    • pp.6619-6623
    • /
    • 2013
  • Background:The aim of the research was to explore a cost effective, fast, easy to perform, and sensitive method for epidermal growth factor receptor (EGFR) mutation testing. Methods: High resolution melting analysis (HRM) was introduced to evaluate the efficacy of the analysis for dectecting EGFR mutations in exons 18 to 21 using formalin-fixed paraffin-embedded (FFPE) tissues and plasma free DNA from 120 patients. Results: The total EGFR mutation rate was 37.5% (45/120) detected by direct sequencing. There were 48 mutations in 120 FFPE tissues assessed by HRM. For plasma free DNA, the EGFR mutation rate was 25.8% (31/120). The sensitivity of HRM assays in FFPE samples was 100% by HRM. There was a low false-positive mutation rate but a high false-negative rate in plasma free DNA detected by HRM. Conclusions: Our results show that HRM analysis has the advantage of small tumor sample need. HRM applied with plasma free DNA showed a high false-negative rate but a low false-positive rate. Further research into appropriate methods and analysis needs to be performed before HRM for plasma free DNA could be accepted as an option in diagnostic or screening settings.

Identification of the Interaction between Rat Translationally Controlled Tumor Protein/IgE-dependent Histamine Releasing Factor and Myosin Light Chain

  • Kim, Min-Jeong;Jung, Jae-Hoon;Choi, Eung-Chil;Park, Hae-Young;Lee, Kyung-Lim
    • BMB Reports
    • /
    • v.34 no.6
    • /
    • pp.526-530
    • /
    • 2001
  • The translationally controlled tumor protein (TCTP), also known as the IgE-dependent histamine releasing factor (HRF), was used in the yeast two-hybrid system to screen the interacting molecules. We obtained the N-terminus truncated rat fast myosin alkai light chain from the rat skeletal muscle cDNA library in the screening. Since either TCTP/HRF or the myosin light chain is known to be associated with histamine secretion from RBL-2H3 cells, we investigated the possible interaction between rat TCTP/HRF and nonmuscle myosin light chain in these cells. We used affinity chromatography and coimmunoprecipitation. Our data suggests that HRF and the myosin light chain interact, which may play an important role in histamine release in RBL-2H3 cells.

  • PDF

Propane Reforming in Gliding Arc Plasma Reformer for SynGas Generation (합성가스 생성을 위한 글라이딩 아크 플라즈마 개질기에서 프로판 개질)

  • Yang, Yoon-Cheol;Chun, Young-Nam
    • Transactions of the Korean Society of Mechanical Engineers B
    • /
    • v.33 no.11
    • /
    • pp.869-875
    • /
    • 2009
  • The purpose of this paper is to investigate the optimal condition of the syngas production by reforming of propane using Gliding arc plasma reformer. The gliding arc plasma reformer in 3 phases has been newly designed and developed with a quick starting and fast response time. It can be applicable to the various types of fuels (Hydrocarbons $C_xH_y$), and it has a high conversion rate of fuels and high production of hydrogen. The parametric screening studies were carried out according to the changes of a steam feed amount i.e., steam/carbon ratio, total gas flow rate and input electric power. The optimum operating conditions were S/C ratio 2.8, total gas flow rate of 14 L/min and input electric power of 2.4 kW. The result of optimum operating conditions showed the 55 % $H_2$, 14 % CO, 15 % $CO_2$, 10 % $C_3H_8$ and 4 % $CH_4$. Also, $C_3H_8$ conversion, $H_2$ yield and $H_2$ selectivity were 90 %, 42 %, 15 %, respectively. The energy efficiency and specific energy requirements were 37 % and 334 kJ/mol respectively.

Preventive Control Using Generation Rescheduling for Transient Stability (과도안정도 측면에서의 발전 재배분을 이 용한 예방제어)

  • Lee, Jong-Seok;Lee, Byeong-Jun;Gwon, Se-Hyeok;Choe, Seon-Gyu;Nam, Hae-Gon;Chu, Jin-Bu;Jeon, Dong-Hun
    • The Transactions of the Korean Institute of Electrical Engineers A
    • /
    • v.51 no.6
    • /
    • pp.262-268
    • /
    • 2002
  • Preventive control has to solve two important problems. The first is fast and accurate severity assessment of instability originated from the occurrence of a dangerous contingency. The second is to choose an action able to stabilize it. In this paper we assess contingencies in power systems using PASF(Power Angle Shape Filtering) and control power systems by a generation rescheduling. The control action stabilize the whole set of harmful contingencies simultaneously. Note that conventional time-domain transient stability methods can hardly tackle preventive control. So, we study the preventive control using off-line method. The proposed method is applied to prevent and to correct loss of synchronism of all the generators in a operating systems data.

Effect of Ultrasonic Microdroplet Generation in the Low-Temperature Plasma Ionization-Mass Spectrometry

  • Lee, Hyoung Jun;Yim, Yong-Hyeon
    • Mass Spectrometry Letters
    • /
    • v.10 no.4
    • /
    • pp.103-107
    • /
    • 2019
  • Low-temperature plasma (LTP) ionization is one of the ambient ionization methods typically used in mass spectrometry (MS) for fast screening of chemicals with minimal or no sample preparation. In spite of various advantages of LTP ionization method, including simple instrumentation and in-situ analysis, more general applications of the method are limited due to poor desorption of analytes with low volatilities and low ionization efficiencies in the negative ion mode. In order to overcome these limitations, an ultrasonic vibrator of a commercial hand-held humidifier was interfaced with an LTP ionization source, which generated microdroplets from sample solutions and assisted with LTP ionization. Ionization behaviors of various chemicals in microdroplet-assisted LTP (MA LTP) were tested and compared with typical LTP ionization from dried samples applied on a surface. MA LTP efficiently ionized small organic, amino, and fatty acids with low volatilities and high polarities, which were hardly ionized using the standard LTP method. Facile interaction of LTP with ultrafine droplets generated by ultrasonic resonator allows efficient ionization of relatively non-volatile and polar analytes both in the positive and negative ion modes.

Rapid Detection of Cadmium-Resistant Plant Growth Promotory Rhizobacteria: A Perspective of ELISA and QCM-Based Immunosensor

  • Agrawal, Ruchi;Satlewal, Alok;Chaudhary, Manav;Verma, Amit;Singh, Rachna;Verma, A.K.;Kumar, Rajesh;Singh, K.P.
    • Journal of Microbiology and Biotechnology
    • /
    • v.22 no.6
    • /
    • pp.849-855
    • /
    • 2012
  • Plant growth-promoting rhizobacteria (PGPR) pseudomonads have a large number of lipopolysaccharides on the cell surface, which induces immune responses. Cd-resistant PGPR prevalent at the Cd-affected sites under biophytostabilization was monitored. Transmissiom electron microscopy was used to the study the behavior of tolerance of PGPR to cadmium level and its effect on pseudomonad strains (Z9, S2, KNP2, CRPF, and NBRI). An immunosensor was developed by immobilizing antibody (anti-Z9 or anti-S2) against selected PGPR on a piezoelectric quartz crystal microbalance (QCM). Immunosensors were found to supplement the inherent specificity of antigen-antibody reactions with the high sensitivity of a physical transducer. On comparison of the efficiency of detection with ELISA, the spectrophotometric technique, the developed immunosensor was found to be more sensitive, fast, and reliable even after regeneration for several times. Thus, the immunosensor may be used for future detection of PGPR strains after automation of the screening process.

Development of the Contingency Analysis Program of Korean Energy Management System (한국형 에너지 관리시스템용 상정고장 해석프로그램 개발)

  • Cho, Yoon-Sung;Yun, Sang-Yun
    • The Transactions of The Korean Institute of Electrical Engineers
    • /
    • v.59 no.2
    • /
    • pp.232-241
    • /
    • 2010
  • This paper describes the development of robust contingency analysis program for Korean Energy Management System. The important function of contingency analysis is to determine the bus/branch model for contingency, and to calculate the state of the power network based on the network model and topology output. In the proposed method, the bus/branch models for contingencies are determined exactly using a fast linked-list method based on the application common model database. To calculate the state of the power system included contingency, the full-decoupled powerflow approach, the partial powerflow method for contingencies and the proposed contingency screening algorithm are also used to contingency analysis. To verify the performance of the developed processor, we performed a file-based test using several structured input data and online test using the database which resides on memory. The results of these comprehensive tests showed that the developed processors can accurately calculate the power system contingency state from online data and can be applied to Korea Power Exchange system.

Development of Enhanced Contingency Screening and Selection Algorithm for On-line Transient Security Assessment (과도안전도 평가를 위한 개선된 상정고장 선택 및 여과 알고리즘 개발)

  • Kim Yong-Hak;Song Sung-Geun;Nam Hae-Kon
    • The Transactions of the Korean Institute of Electrical Engineers A
    • /
    • v.54 no.6
    • /
    • pp.306-314
    • /
    • 2005
  • In this paper, a new approach that is based on EEAC & only with network solutions for CS&S in the transient stability assessment is developed. The proposed CS&S algorithm in conjunction with EEAC to include the capability of performing on-line TSA without TDS is used to calculate the critical clearing time for stability index. In this algorithm, all generators are represented by classical models and all loads are represented by constant impedance load models. The accelerating & synchronizing power coefficient as an index is determined at its disturbance through solving network equation directly. As mentioned above, a new index for generator is generally used to determine the critical generators group. The generator rotor angle is fixed for non-critical generators group, but has equal angle increments for critical generators group. Finally, the critical clearing time is calculated from the power-angle relationship of equivalent OMIB system. The proposed CS&S algorithm currently being implemented is applied to the KEPCO system. The CS&S result was remarkably similar to TSAT program and SIME. Therefore, it was found to be suitable for a fast & highly efficient CS&S algorithm in TSA. The time of CS&S for the 139 contingencies using proposed CS&S algorithm takes less than 3 seconds on Pentium 4, 3GHz Desktop.

Development of a Compact Nuclear Hydrogen Coupled Components Test Loop (원자로수소생산을 위한 연결부품 실험용 소형 컴팩트 실험장치 개발)

  • Hong, S.D.;Kim, J.H.;Kim, C.S.;Kim, Y.W.;Lee, W.J.
    • Proceedings of the KSME Conference
    • /
    • 2008.11b
    • /
    • pp.2850-2855
    • /
    • 2008
  • Very High Temperature Reactor (VHTR) has been selected as a high energy heat source for a nuclear hydrogen generation. The VHTR heat is transferred to a thermo-chemical hydrogen production process through an intermediate loop. Both Process Heat Exchanger and sulfuric acid evaporator provide the coupled components between the VHTR intermediate loop and hydrogen production module. A small scaled Compact Nuclear Hydrogen Coupled Components test loop is developed to simulate the VHTR intermediate loop and hydrogen production module. Main objective of the loop is to screening the candidates of NHDD (Nuclear Hydrogen Development and Demonstration) coupled components. The operating condition of the gas loop is a temperature up to $950^{\circ}C$ and a pressure up to 6.0MPa. The thermal and fluid dynamic design of the loop is dependent on the structures that enclose the gas flow, especially primary side that has fast gas velocity. We designed and constructed a small scale sulfuric acid experimental system which can simulate a part of the hydrogen production module also.

  • PDF