• Herbal Formula Science
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• v.28 no.1
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• pp.63-70
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• 2020

Objectives : The purpose of this study was to investigate the anti-cancer effects of 18α-Glycyrrhetinic acid (18α-GA), a hydrolyzed metabolite of glycyrrhizin, in AGS human gastric adenocarcinoma cells. Methods : We used human gastric adenocarcinoma cell line, AGS cells. We examined cell death by MTT assay and caspase 3 and 9 assay with 18α-GA. To examine the inhibitory effects of 18α-GA, sub-G1 analysis was done the AGS cells after 24 hours with 18α-GA. Also, to investigate the inhibitory mechanisms of 18α-GA, mitogen-activated protein kinase pathways and reactive oxygen species (ROS) generation were examined. Results : 1. 18α-GA inhibited the growth of AGS cells in a dose-dependent fashion. 2. Sub-G1 fractions were significantly and dose-dependently increased by 18α-GA. 3. 18α-GA increased the caspase 3 and 9 activities in AGS cells. 4. 18α-GA inhibited proliferation of AGS cells via the modulation of c‑Jun N‑terminal kinase (JNK) signaling pathways, which results in the induction of apoptosis. 5. 18α-GA enhanced ROS accumulation in AGS cells. Conclusions : Our findings provide insight into unraveling the effects of 18α-GA in human gastric adenocarcinoma cells and developing therapeutic agents against gastric cancer.

• The Journal of the Korea Contents Association
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• v.10 no.5
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• pp.173-184
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• 2010

The living standards of Chinese people are gradually rising, which has led more Chinese students to come to Korea for their academic career. In this respect, it seems significant to find out how clothing involvement affects brand attachment and brand loyalty of Chinese college students in Busan. In this study, we attempt to identify factors of clothing involvement that influence Chinese students' turn of mind towards brand attachment and brand loyalty. The results of our analysis are as follows: 1. Five factors of clothing involvement have been derived: fashion trend, favorable impression, planning, indifference and choice. For brand attachment, three factors of brand show-off, brand gravity and brand pride have been derived. 2. Factors of clothing involvement have positive effects on factors of brand attachment, and brand attachment also have significant effects on brand loyalty. 3. Clothing involvement significantly affects brand loyalty indirectly via brand attachment.

• The Journal of the Korea Contents Association
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• v.13 no.9
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• pp.369-381
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• 2013

The purpose of the study was to divide social commerce websites' information into components of product, price, service, and seller information, and to systematically analyze each component of information. A content analysis was used as a research methodology, and 100 webpages from social commerce websites were analyzed. As results, the social commerce websites provided basic information (front view, fabric contents, country of origin, care, color, size) for product information and emphasized price information, including discount rates, sales dues, product quantity, and the amount of products sold. They basically provided expected delivery date, delivery company, Q&A, and return/refund service for service information. In addition, they basically presented brand logo and brand name but need to add information about brand concepts, history and volume as seller information. This study suggested diverse theoretical and practical implications of social commerce information.

• The Journal of Society for e-Business Studies
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• v.22 no.4
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• pp.117-128
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• 2017

The increased national utilization of Bitcoin results in multiple complications. Therefore, there are continuous debates on the subject, the main point being how to characterize Bitcoin's asset nature. The following study bases, focusing on the function value, justifies Bitcoin's asset characterization. Using regression analysis to construct relations between gold and indexes such as CPI, DXY, and S&P500 as well as the relation between Bitcoin and the previously mentioned indexes, the question of whether gold and Bitcoin reacted in a similar fashion to the same indicators was examined. The results conclude that Bitcoin has similarities with gold, showing that it is risk averse and an investable commodity in lieu to profitability when it comes to inflation and currency value. When considered with price volatility, the main force behind the function of investment asset, categorizing Bitcoin as a high-risk financial investment asset rather than as a currency within the system would be more effective for management.

• The Research Journal of the Costume Culture
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• v.15 no.1 s.66
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• pp.1-12
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• 2007

The purpose of this study is to identify the SPA(Specialty store retailer of Private label Apparel) characteristics and product supply process of Korean casual apparel brands. The research was conducted by questionnaire surveys to 63 casual apparel brands. SPA characteristics of each brand were measured with four SPA characteristic indices: short product supply cycle, spacious retail floor, single brand retail store, and low product price compared to the quality of the product. The 63 apparel brands were grouped by SPA index score. The brands belonged to group H had high index score and brands in group L had low index score. The results of this study showed that the most of the casual apparel brands' products were sold at department stores, especially the brands belonged to group L greatly depended on department stores. Few apparel brands have spacious retail floor. The retail product price of the brands belonged to group H was low price while the product price of the brands belonged to group L was in the medium-high price. The supply time of the new products was short in general. The most brands supplied new styles to the retail floor within 1 to 3 weeks. The information technology was heavily used. The brands belonged to group H highly used information technology including bar codes system, pas data analysis, and inventory control system. The current style trends were analyzed with street fashion and feedback from the shop managers.

• The Research Journal of the Costume Culture
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• v.15 no.1 s.66
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• pp.137-151
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• 2007

This study was performed to narrow down the Sizing System for Female Adult's garments(KS K 0051) following age target and body shapes. The study was based on the sizing system and the anthropometric measurements, called Size-Korea, which were surveyed in the years 2003 and 2004. At first, the subjects of the survey were classified into 4 age groups, $18{\sim}24,\;25{\sim}34,\;35{\sim}49\;and\;50{\sim}59$, based on the most significant differences of body sizes. Secondly, the ranges of four key dimensions - height, bust, waist and hip-of normal sizes were identified through analyzing Rohrer index and percentile. The selected sizes within the ranges were grouped by the drop which was the subtraction of bust girth from hip girth. In conclusion, there was the most frequent drop for each age group; 9cm drop for the $18{\sim}24$ years old group, the 6cm drop for the $25{\sim}34$ years old and $35{\sim}49$ years old and 3cm drop for $50{\sim}59$ years old. The upper body garment sizes of the same drop and target ages could be merged to 10 to 12 sizes, which were remarkably smaller than the Female Adult garment sizing system, and further to 2-5 sizes, considering the percentile importance. However, $50{\sim}59$ years old group needed to be analyzed in different ways, because the number of subjects of normal size in the age decreased rapidly, that the normal sizes for them were very limited. In addition, the reference body sizes of each garment size were apparently different when they were compared to each age groups. These basic data for garment size specification could be usefully adapted for the apparel companies' own sizing system according to their age target and body shapes, to achieve efficient production and better fit.

• The Research Journal of the Costume Culture
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• v.15 no.3 s.68
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• pp.420-430
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• 2007

Noting that there is an increasing trend of the so-called 'neo-single life style' among women these days, this research aims to make a product development for these neo-single women in this era of families of a single member by analyzing their concepts and characteristics. We payed a particular attention to the data from such sources as newspapers, magazines or the articles in the Internet. The essence of our research lies in the analysis of target market, in the suggestions in the brand planning and product development and in the designs of fashion and interior products for them. The result of this research is as follows. First, it turns out that these neo-single women enjoy a kind of multi-mixing code lifestyle rather than showing a preference for a particular brand. For this reason, we have decided to pursue a multi-concept brand fonn as a right direction for brand planning for them. Second, as for a philosophy behind the brands, we suggest a concept of 'small utopia' for neo-single women and express such as new aristocracy, happiness and pleasure. Third, we adopt 'YOU' as the name of the brand as it reflects their various life styles and characteristics. Fourth, as for the product development of F/W in 2007, we have decided on 'Minimal Natural' as it mixes up the concepts of the controlled beauty of sophistication and multi-functional elements and 'Modern Primitive' as it expresses the ethnic elements on modern images having craft factors and modern images. We have performed concrete tasks in creating images, coloring, making fabrics for each theme. Fifth, we have chosen and suggested other products that are suitable for these neo-single women who seek for multi-functional but simple kinds after surveying a wide range of products in magazines or in the Internet.

• Journal of Acupuncture Research
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• v.20 no.3
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• pp.45-62
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• 2003

Objective : To examine the effects of Beevenom on the cell proliferation of human breast carcinoma cell line MCF-7, we performed various experiments such as does-dependent effect of Beevenom on cell proliferation and viability, morphological changes, and alterations of apoptosis/cell cycle-regulatory gene products. Methods : Beevenom induced cell viability and proliferation of MCF-7 cells in a concentration-dependent manner. The anti-proliferative effect by Beevenom treatment in MCF-7 cells was associated with morphological changes such as membrance shrinking and cell rounding up. Results : Beevenom induced apoptotic cell death in a concentration-dependent manager, which was associated with degradation of ${\beta}$-catenin, an apoptotic target protein. Beevenom induced the Bax expressions, a pro-apoptotic gene, both in protein and mRNA levels, however, the levels of Bcl-$X_{S/L}$ expression, an anti-apoptotic gene, were down-regulated in Beevenom-treated cells. Western blot analysis and RT-PCT data revealed that the levels of cyclin of B1 protein and cyclin E mRNA were reduced by Beevenom treatment in MCF-7 cells, respectively, where as the expression of tumor suppressor p53 and cyclin dependent kinase inhibitor p21 mRNA were markedly increased in a concentration-dependent fashion. Conclusions : Taken together, these findings suggest that Beevenom induced inhibition of human breast cancer cell proliferation is associated with the induction of apoptotic cell death and Beevenom may have therapeutic potential in human breast cancer.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2003.10a
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• pp.699-702
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• 2003

Most of current shopping malls do not satisfy everyone because they present arrangements of goods and suggestions uniformly and comprehensively according to the thinking of their managers. On the other hand not the standard of selection but the comparison of price plays a decisive role of the purchase of goods as similar form each other. When classifying into groups according to generations, gender, income, job, hobby, etc. the propensity of purchase is showed differently and the interest and real purchasing power of the individual is different in shopping malls. It also will maximize the purchasing power of customers to make and implement the sales strategy more quickly as the basis of fashion and season of environmental factors and natural calamity of environmental variable according to the economic principle. This paper concentrates on the design and implementation of intelligent shopping mall that is added the sales strategy according to environmental variable and can not only analysis, update and classify the propensity of purchase continuously but also construct optimal goods automatically.

• Journal of the Korean Society of Costume
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• v.59 no.7
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• pp.65-76
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• 2009

Korea has established a code for the economic and cultural industry that covers a wide range of classes unlike the old information era which was limited to the simple knowledge, technology, tools, morals, and customers that had been established in our society. On the other hand, 'culture marketing' is a series of marketing activities in which value-added items are created and shared. The combination of business management and culture seemed pretty awkward considering how rapidly the world was changing, however, the nature of today's culture has changed and the economic nature of culture products has resulted from those changes. In this paper, two authors who expressed the cultural identity in the culture products are studied through a comparison analysis; the author Min Yeongsoon expressed the identity confusion that she experienced in a foreign country and how she overcame homesickness in her work; and the author Kim Ata expressed his confidence in Asia and used his clear and loud voice to express the culture in his work. In addition, today's culture products are affected by the surrounding cultures such as the member's traditional society, environmental culture, and individual's culture. It is a good source for good works of art. In this study, the efforts of seeking the cultural identity, structuring the concept, seeking a new market and possibilities are used to make a consistent process in order to make a series of the systems required for planning and developing culture products.