• 제목/요약/키워드: far transfer

검색결과 393건 처리시간 0.023초

Proteomic Analysis of the Aging-related Proteins in Human Normal Colon Epithelial Tissue

  • Li, Ming;Xiao, Zhi-Qiang;Chen, Zhu-Chu;Li, Jian-Ling;Li, Cui;Zhang, Peng-Fei;Li, Mao-Yu
    • BMB Reports
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    • 제40권1호
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    • pp.72-81
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    • 2007
  • In order to screen the aging related proteins in human normal colon epithelia, the comparative proteomics analysis was applied to get the two-dimensional electrophoresis (2-DE) profiles with high resolution and reproducibility from normal colon epithelial tissues of young and aged people. Differential proteins between the colon epithelia of two age groups were found with PDQuest software. The thirty five differential protein-spots were identified by peptide mass fingerprint (PMF) based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) and database searching. Among them there are sixteen proteins which are significantly up-regulated in the colonic mucosal epithelia of young people group, which include ATP synthase beta chain, electron transfer flavoprotein alpha-subunit, catalase, glutathione peroxidase 1, annexin A2 and heat shock cognate 71 kDa protein, etc.; There are nineteen proteins which are significantly up-regulated in the colonic mucosal epithelia of aged people group, which include far upstream element-binding protein 1, nucleoside diphosphate kinase B, protein disulfide-isomerase precursor and VDAC-2, etc.. The identified differential proteins appear to be involved in metabolism, energy generation, chaperone, antioxidation, signal transduction, protein folding and apoptosis. The data will help to understand the molecular mechanisms of human colon epithelial aging.

대향류 핀삽입형 재생증발식 냉방기의 냉방성능 (Cooling Performance of a Counterflow Regenerative Evaporative Cooler with Finned Channels)

  • 문현기;이대영
    • 설비공학논문집
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    • 제20권7호
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    • pp.462-469
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    • 2008
  • A regenerative evaporative cooler has been fabricated and tested for the evaluation of cooling performance. The regenerative evaporative cooler is a kind of indirect evaporative cooler comprised of multiple pairs of dry and wet channels. The air flowing through the dry channels is cooled without any change in the humidity and at the outlet of the dry channel a part of air is redirected to the wet channel where the evaporative cooling takes place. The regenerative evaporative cooler fabricated in this study consists of the multiple pairs of finned channels in counterflow arrangement. The fins and heat transfer plates were made of aluminum and brazed for good thermal connection. Thin porous layer coating was applied to the internal surface of the wet channel to improve surface wettability. The regenerative evaporative cooler was placed in a climate chamber and tested at various operation condition. The cooling performance is found greatly influenced by the evaporation water flow rate. To improve the cooling performance, the evaporation water flow rate needs to be minimized as far as the even distribution of the evaporation water is secured. At the inlet condition of $32^{\circ}C$ and 50%RH, the outlet temperature was measured at $22^{\circ}C$ which is well below the inlet wet-bulb temperature of $23.7^{\circ}C$.

플라잉디스크 포핸드 및 백핸드 던지기 동작의 운동학적 특성 비교 (A comparative analysis of the kinematical characteristics of Forehand & Backhand Flying Disc Throwing)

  • 김미향;박종철;변경석
    • 디지털융복합연구
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    • 제17권12호
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    • pp.555-563
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    • 2019
  • 본 연구는 플라잉디스크의 포핸드와 백핸드 던지기 동작에 대한 정량적 기초자료를 제공하기 위해 수행하였으며 이를 위해 3차원 동작분석 기법을 활용하여 운동학적 변인을 산출하였다. 연구 변인을 종합하여 분석한 결과 플라잉디스크는 멀리 던지는 것뿐만 아니라 정확하게 던지는 것이 중요하므로 P2와 P3에서는 전방으로의 이동을 제어하고 관절의 회전 운동에 집중해야하는 것으로 나타났다. 또한 효율적인 회전 운동을 위해 골반에서 몸통으로 회전력 전이가 중요한 것으로 판단된다. 포핸드는 상지 관절의 움직임을 주로 활용하여 던지기 동작을 수행하는 반면 백핸드 던지기는 비교적 몸통 및 골반의 회전을 주로 활용하여 던지는 것으로 나타났다. 본 연구의 정량적 자료를 바탕으로 플라잉디스크 현장 교육을 위한 기초자료로 활용될 수 있기를 기대한다.

골유착성 임플랜트 보철물의 캔틸레버 위치와 길이변화에 따른 삼차원 유한요소법적 응력분석 (A THREE DIMENSIONAL FINITE ELEMENT STRESS ANALYSIS OF OSSEOINTEGRATED PROSTHESIS ACCORDING TO THE LOCATION AND LENGTH OF CANTILEVER)

  • 장복숙;김창회;김영수
    • 대한치과보철학회지
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    • 제34권3호
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    • pp.501-532
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    • 1996
  • This study investigated the effects of cantilever length, location and load condition on stress distribution developed in the implants, prostheses and supporting tissues. The osseointegrated prostheses with two 10mm Branemark implants at 2nd premolar and 1st molar sites with cantilever extensions at 1st premolar, 2nd and 3rd molar sites were constructed. Under 100N, 200N of vertical and $45^{\circ}$ oblique loads at the cantilever pontics, stress distribution patterns and displacement were analyzed with three dimensional finite element method. The results were as follows : 1. The stress was concentrated at the joint of the cantilever pontic and implant superstructure, the neck of implant and the ridge crest near the cantilever But there was little load transfer to the lower supporting tissues of implants. 2. The implant near the cantilever was displaced inferiorly while the implant far from the cantilever was displaced superiorly. In horizontal direction the implants were displaced to the direction where the loads were applied, except the apexes of the implants. 3. In case of anterior cantilever, the stress and displacement were higher than the prosthesis connected with natural tooth. 4. The stress developed in the posterior cantilevered type was higher than in the anterior cantilevered type. The greastest stress was concentrated at the ridge crest near the posterior cantilever. 5. The longer the cantilever, the more the stress was developed and was concentrated at the joint of the cantilever pontic and implant superstructure. 6. Under oblique load, the stress was concentrated at the necks of implants and the ridge crests, but decreased at the joint of the cantilever pontic and implant superstructure than under vertical load.

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원자외선 분광기 TDC 및 LVPS 전자보드의 열 해석 (THERMAL ANALYSIS OF FIMS TDC AND LVPS ELECTRONIC BOARDS)

  • 선광일;육인수;남욱원;진호;박장현;이진근;유광선;이대희;오승한;공경남;한원용;민경욱
    • Journal of Astronomy and Space Sciences
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    • 제19권4호
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    • pp.283-292
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    • 2002
  • 과학위성 1호의 탑재체 원자외선 분광기의 전자보드는 인공위성 운영시 경험하는 환경하에서 전자적 성능을 유지하기 위하여 전자부품의 온도가 지나치게 높아지지 않도록 열적 특성을 고려하여 설계하여야 한다. 이를 위하여 원자외선 분광기의 전자부의 보드수준에서 열 해석을 수행하였고, 원자외선 분광기의 작동환경하에서 전자부품의 허용온도 범위내에서 온도가 유지될 수 있음을 확인하였다.

실내디자인에서 'Mix & Match'의 속성 및 표현특성에 관한 연구 (A Study on the Attributes and Expression Characteristics of 'Mix & Match' in Interior Design)

  • 조성희;최인영
    • 한국실내디자인학회논문집
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    • 제19권1호
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    • pp.55-62
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    • 2010
  • This study examines attributes and expression characteristics of 'Mix & Match' which is one of the major current trends in interior designs. The concept and background of 'Mix & Match' was ascertained through research of previous documents and studies, and its attributes were explored. In order to examine the expression characteristics to see how they are expressed in actual interior designs, case analyses were carried out centering on the expression elements such as material, light & lighting, color, furniture and objects which were regarded as important in previous studies and related articles so far. The case analyses were carried out for works where the concept of 'Mix & Match' was prominent in designs produced in 2007 and 2008, chosen from the main reports of the representative interior design journals, 'Interiors' and 'INTERNI & Decor'. As a result, it has been found that 'Mix & Match' is not limited to one attribute but the temporal, spatial and genre attributes are present all at the same time, or various expression elements exist in one attribute. This is a distinct character commonly shown in most of the cases and each expression element is expressed in variety according to spatial concept, from a simple parallel to substitution, transfer and modification (simplification, transformation of the scale, rate modification etc.) Therefore, in creating the space for 'Mix & Match' or in interpretation of it, the understanding of these expression characteristics would make it possible for clearer and more various applications of design, and furthermore will be meaningful for supply and accumulation of reference in design communication.

국민주택규모 단위세대 평면 분석 연구 - 2005년 이후 대한주택공사 사례를 면적분석 중심으로 - (Analytical Study for the Plan of Unit Household in National Housing Scale - Oriented on the cases of Korea housing corporation since 2005 ; Focused on analysing area)

  • 이정호;이찬
    • 한국실내디자인학회논문집
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    • 제19권1호
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    • pp.180-189
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    • 2010
  • Since collective houses are started to be supplied, the housing market has been transformed from supplier to demander oriented, and various type with same area of unit households have been deigned and started to be distributed. It can be expected that such transfer phenomenon would be continuously sped-up, and unit household will be more subdivided and varied. Thus, we analysed and studied the planes with subject of unit households in national housing scale ($85m^2$) that is treated as supply standard and has biggest volume in construction by Korean housing corporation. The analysing method is investigating the area of each room within unit household, calculating their minimum, maximum, and average values, studying the efficiency of unit household plane according to the structure of each room by comparative analysis these values, and analysing changing matter by investigating any change of each room area. The analysing results of which are followings. At first, number of BAY on face is increasing. Second, allocation of each room has been vary. Third, area ratio among bedroom1, livingroom, diningroom/kitchen become similar. Fourth, the area of diningroom/kitchen become somewhat bigger. Fifth, the space for passage way is efficiently allocated. Sixth, service area is reduced, Seventh, stereotyped phenomenon Is appeared. Based on many studies so far, any improvements of unit householder in national housing scale are followings. First, in terms of forming style, unit householder in national housing scale is unfolded in various way though, the form of each room is not more than typical style. Second, it shows stereotyped phenomenon. Especially, bathroom 1, 2 show stereotyped feature in terms of their type and area across entire research years, also LDK allocation method is stereotyped, as well as stereotyped trend in bedroom 2, 3, allocation for 4 BAY type.

XML에 기반한 EDI 문서교환 시스템 설계 및 구현 (Design and Implementation of EDI Document Exchange system based on XML)

  • 임영태;한우용;정회경
    • 한국정보처리학회논문지
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    • 제7권11S호
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    • pp.3603-3612
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    • 2000
  • 본 논문에서는 XML(eXxtensible Markup Language)을 이용하여 고정적이고 정형화된 EDI(Electronic Data Interchange) 문서를 유동적이고 효율적으로 처리하기 위한 시스템을 설계 및 구현하였다. 본 시스템에서는 사용자가 원하는 문서를 직접 생성할 수 있도록 트랜잭션(Transaction) 처리기와 템플리트(Template) 관리기를 설계 및 구현하였으며, 기존 EDI와의 호환을 위해 변환기를 설계하였다. 또한, 본 시스템의 경우 변환에 반드시 필요한 EDI 메시지 구조를 XML 형식으로 저장하고, 이것을 DOM API로 관리하도록 하여 XML의 구조정보를 이용하여 기존 시스템과의 호환성을 고려하였으며, 사용자가 변환기를 이용하여 템플리트 파일을 생성할 수 있고 필요한 구성요소(elements)를 선택 전송할 수 있도록 해당 인터페이스를 제공하도록 하여, 사용자가 전송할 엘리먼트를 선택할 수 있는 인터페이스를 제공하였다. 그리고 아직까지 다른 시스템에서는 문서의 변환에 관한 적절한 해법을 제시하지 못하고 있지만 본 시스템에서는 기존의 시스템이 제공하지 못하는 XML기반의 EDI문서 변환 기법 및 구조정보를 제공하여 그 해법을 제안하고 있다.

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광주·전남의 구급대 활동분석 및 발전방안

  • 박희진;오용교
    • 한국응급구조학회지
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    • 제1권1호
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    • pp.71-86
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    • 1997
  • This study is to suggest some developmental policies by analyzing the activities of first aid party in Kwangju and Chonnam regions for two years from Jan. 1, 1991 to the end of December, 1995. First, the residents in Kwangju and Chonnam regions have the sufficient benefits of emergency medical center, but it will be desirable that general hospital should be established and managed in Kohung peninsula which forms the wide island area far away from big cities. Second, the classification of the degree of severe case in the field by rescue members should be strengthened as the means which can reduce the number of patients transferred to the emergency room and the legal method which rescue members can select the medical agency. Third, children less than 10 are most frequent emergent patients and it is due to parent's indifference and children's in sensibility to safety. So the safely education in the course of infant and elementary education should be strengthened and the method which can keep the self safety through the legal system. Fourth, to increase the rate of emergency measure by rescue members, the reasons of fail of emergency treatment are suggested, the treatment results of each rescue member are analyzed every year and it is desirable that the system which can evaluate the personal ability should be introduced. Fifth, the medical accidents occurred in the case of medical act, by rescue members must lake the legal responsibility, but such a problem can he solved with the compensation of insurance system by government. Sixth, to reduce the time required for transfer, traveling service system for the fixed period in beach should be complemented and extended more and service system at ordinary times should be examined at mountains, the area of traffic jams and large special industrial park. Seventh, since service system with one team of two members of 119 rescue party in expressway cannot be mobilized when multiple accidents occur at the same time, it is considered that service system of two teams of four members should be extended. Eighth, first-aid service in expressway is conducted with rescue and emergency treatment by the rescue party at the same time, but the professional rescue lacks and it may result in the injury of patients. Therefore the creation of rescue party in expressway is the urgent problem.

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Influence of column yielding on degree of consolidation of soft foundations improved by deep mixed columns

  • Jiang, Yan;Han, Jie;Zheng, Gang
    • Geomechanics and Engineering
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    • 제6권2호
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    • pp.173-194
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    • 2014
  • Laboratory and field data showed that deep mixed (DM) columns accelerated the rate of consolidation of the soft foundations. Most analyses of consolidation of DM column-improved foundations so far have been based on the elastic theory. In reality, the DM columns may yield due to the stress concentration from the soft soil and its limited strength. The influence of column yielding on the degree of consolidation of the soft foundation improved by DM columns has not been well investigated. A three-dimensional mechanically and hydraulically-coupled numerical method was adopted in this study to investigate the degree of consolidation of the DM column foundation considering column yielding. A unit cell model was used, in which the soil was modeled as a linearly elastic material. For a comparison purpose, the DM column was modeled as an elastic or elastic-plastic material. This study examined the aspects of stress transfer, settlement, and degree of consolidation of the foundations without or with the consideration of the yielding of the DM column. A parametric study was conducted to investigate the influence of the column yielding on the stress concentration ratio, settlement, and average degree of consolidation of the DM column foundation. The stress concentration ratio increased and then decreased to reach a constant value with the increase of the column modulus and time. A simplified method was proposed to calculate the maximum stress concentration ratios under undrained and drained conditions considering the column yielding. The simplified method based on a composite foundation concept could conservatively estimate the consolidation settlement. An increase of the column modulus, area replacement ratio, and/or column permeability increased the rate of consolidation.