• Title/Summary/Keyword: family-of-origin

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Prenatal diagnosis of interchromosomal insertion of Y chromosome heterochromatin in a family

  • Lee, Bom-Yi;Park, Ju-Yeon;Lee, Yeon-Woo;Oh, Ah-Rum;Lee, Shin-Young;Park, So-Yeon;Ryu, Hyun-Mee;Lee, Si-Won
    • Journal of Genetic Medicine
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    • v.14 no.2
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    • pp.62-66
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    • 2017
  • Interchromosomal insertion of Y chromosome heterochromatin in an autosome was identified in a fetus and a family. A fetal karyotype was analyzed as 46,XX,dup(7)(?q22q21.1) in a referred amniocentesis at 16 weeks of gestation for advanced maternal age. In the familial karyotype analyses for identification of der(7), the mother, the first daughter and the maternal grandmother showed the same der(7) as the fetus's. CBG-banding was positive at 7q22 region of der(7) that indicated inserted material was originated from heterochromatin. The origin of heterochromatic insertion region in der(7) of the fetus and the mother was found in Yq12 region by fluorescent in situ hybridization with a DYZ1 probe. In the specific analysis of Y chromosomal heterochromatic region of ins(7;Y) of the mother, 15 sequence tagged sites from Yp11.3 region including SRY to Yq11.223 region was not detected. Final karyotypes of the mother, the first daughter and the maternal grandmother were reported as 46,XX,der(7)ins(7;Y)(q21.3;q12q12). All female carriers of ins(7;Y) in the family showed normal phenotype and the mother and the maternal grandmother were fertile. A healthy girl was born at term. We report a rare case of familial interchromosomal insertion of Y chromosome heterochromatin detected only in female family members with normal phenotype that was diagnosed prenatally.

The Impact of the Self-Differentiation and Self-Disclosure of Unmarried Persons in Early Adulthood on Their Intimacy with the Opposite Sex (성인초기 미혼남녀의 자아분화와 자기개방이 이성과의 친밀감에 미치는 영향)

  • Choi, Ji-Young;Choi, Youn-Shil
    • Korean Journal of Human Ecology
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    • v.19 no.2
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    • pp.227-244
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    • 2010
  • The purpose of this study was to examine how the family of origin and self-disclosure of unmarried persons in early adulthood affected their own intimacy with the opposite sex, which was one of the major developmental tasks for them. The findings of the study are as follows: First, the self-differentiation, self-disclosure, and intimacy with the opposite sex of the single male and female adults investigated were generally at a moderate level. Second, for self-differentiation, the background variables of the male and female adults made no statistically significant difference. For self-disclosure, the background variables of the female adults made no statistically significant difference to that, but the male adults differed significantly from one another in that regard according to their family makeup and birth of order. As for connections between the background variables of the single male and female adults and their intimacy with the opposite sex, the male adults varied in that aspect with their birth order, and whether they were dating and considered getting married made a difference to that as well. In the event of the female adults, whether they considered getting married and how long they were dating made a difference in their intimacy with the opposite sex. Third, concerning the relative influence of the self-differentiation and self-disclosure of the unmarried male and female adults on their intimacy with the opposite sex, their intimacy with the opposite sex improved as division occurred from their original families, when they opened themselves up to more people, when they thought of marriage more and when they were dating for a longer period of time.

The Study of Naturalized Plants in Ulleungdo (울릉도의 귀화식물에 관한 연구)

  • Hwang, Gyu-Jin;Park, Seong-Jun;Son, Sung-Won;Park, Seon-Joo
    • Korean Journal of Environment and Ecology
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    • v.21 no.1
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    • pp.1-12
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    • 2007
  • Nauralized plants in Ulleungdo were enlisted as 65 taxa, 21 families,49 genera,63 species and 2 varieties by field survey and flora lists of literature cited. Family Compositae covered 27.7% and Family Gramineae, Family Leguminosae and Family Polygonaceae covered 7.7% each. In this study, the nine taxa such as Rumex nipponicus, Trifolium campestre, Oxalis articulata, Anthriscus caucalis, Ipomoea purpurea, Coreopsis Ianceolata, Galinsoga parviflora, Tritonia crocosmaeflora and Festuca arundinacea are added as Nauralized plants in Ulleungdo. Annual plants ratio is 36.9% by life-form spectrum and Europe ratio is 40.0% by origin. The Urbanization Index was 22.0 and the Ratio of Naturalized has increased by flora lists of literature cited each. Ambrosia artemisiifolia var. elatior is growing in Ulleungdo by a plant cause disturbance. Spread prevention and minimization incoming of gardening plants by management plan of naturalized plants might be required. Moreover, it is needed to induce the succession for the recovery of the cut-slope using the native plants.

A Study on Tea Culture and Manner: focused on the Blooming Lotus Pond Tea (차문화와 예절에 관한 연구: 연지화개기호차를 중심으로)

  • Lee Il Hee
    • Journal of Family Resource Management and Policy Review
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    • v.8 no.3
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    • pp.1-14
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    • 2004
  • This is a historical study of the tea culture and its manners after checking the origin of the tea culture in Korea. Also I created the Blooming Lotus Pond Tea which can be utilized in various meetings or at homes in connection with the tea culture and etiquette by studying good manners, clothing and light refreshments in 'Kyucongyogyul' by Lee-E, 'Karyejibramdo' by Kim Jang-Seng and other books of the Chosun Dynasty. I created the Blooming Lotus Pond Tea by referring to the tea-ceremonies described in the poems by Hong Inmo, his wife, Lady Suh, and her descendants. They can be better harmonized with the modem tea culture rather than the strict procedures of traditional court ceremonies or marriage, funeral, and other formal tea ceremonies. About the costumes of the nobilities, that is especially referred to Kyukmongyogyul by Lee-I of the Chosun Dynasty for the etiquette, also 'The Living Manners' by Professor Lee Gilpyo and Choi Baeyong. In addition, the tea-food is made based on 'the five elements'. The Blooming Lotus Pond Tea is made of frozen lotus flowers and prepared in the lotus formed broad-rimmed tea-utensils and supposed to be shared with family members or guests. It's recommended to hold a poetry-party with a tea-party. At present, this kind of daily tea ceremony is being developed at homes. It'll be desirable if it could recreate the traditional way as a ceremonial tea culture. In that case, it'll regain the quality of the traditional etiquette by harmonizing tea culture and manners. Such a tea culture can contribute to the quality of people's ordinary life and the identity of our country.

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Evaluation of Anti-inflammatory activity of Fissistigma poilanei and Rubus laxus Focke

  • Lee, Soo Jung;Suh, Mee-Hyun;Kim, June-Hyun
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.10a
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    • pp.75-75
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    • 2019
  • The aim of the study was to determine the anti-inflammatory activities of the plants with origin of China. The Fissistigma poilanei, which is a species of plant in the family Annonaceae and Rubus laxus Focke, which is a species of plant in the family Rosaceae from China were tested for anti-inflammatory activities. Samples were prepared using 95% ethanol using nitric oxide (NO) assay for assessing the anti-inflammatory activity. NO assay experiment showed that extracts of the Fissistigma poilanei give 28.3% increases in anti-inflammatory activity and extracts of Rubus laxus Focke give 57.1% decreases in anti-inflammatory activity, compared to control. To determine the cell toxicity, MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay was used. MTT assay experiment showed that Fissistigma poilanei and Rubus laxus Focke might have less toxicity of 60.5% and 62.3%, respectively, compared to control. Taken together, these experiments showed that Fissistigma poilanei extracts might have significantly higher anti-inflammatory activities and relatively lower toxicity, compared to control. This implies that this study might give a tool to develop a new potential anti-inflammatory therapeutic candidate.

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Study of Variable Factors Affecting Couple's Marital Satisfaction : Focused on the Related Variable of Myself and Partner (결혼만족도에 영향을 미치는 변인에 관한 연구 : 본인 및 배우자 관련변인을 중심으로)

  • Kim, Hyo-Min;Park, Jeong-Yun
    • Journal of Families and Better Life
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    • v.31 no.3
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    • pp.125-140
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    • 2013
  • In the study of married couples, there has been a great lack of analysis of the factors affecting the marital satisfaction of spouses until now. In this study, the subjects were couples living in Seoul or Gyeonggi Province. The data collection period was November 20 to December 20, 2009, and data ond 184 couples were collected and used for the analysis. The SPSS 17.0 program was used for the analysis. The main findings of this study are as follows: First, the husbands' marital satisfaction was higher than that of the wives. And the variables of spousal support, alternative comparison level and marital dissolution disability were also found to be statistically significant according to gender. Second, it was confirmed that the self-variables had a greater effect than partner variables on couples' marital satisfaction. Third, the influential factors of the marital satisfaction of husbands and wives depended on the individual resource variables (self-esteem, health of origin of family, parenting efficacy), the couple relationship variables (spousal support, spousal similarity, recovery attempts), and the level of marital alternatives.

Antioxidant Activities of Plant Extracts from Carlemannia tetragona and Celastrus virens

  • Lee, Sang-Soo;Yang, Hyun-Young;Kim, June-Hyun
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.10a
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    • pp.74-74
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    • 2019
  • The aim of the study was to determine the antioxidant activities of the plants with origin of the Far East. The Carlemannia tetragona Hook f., which is a species of plant in the family Carlemanniaceae and Celastrus virens which is a species of plant in the family Celastraceae were tested for antioxidant activities. Samples were prepared using 95% ethanol using DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate free radical) assay for assessing the antioxidant activity. Ascorbic acid was used for positive control for DPPH assay. DPPH assay experiment showed that extracts of the Carlemannia tetragona Hook. f., and Celastrus virens might have anti-oxidant activity 54.5% and 258% higher, respectively, compared to control. To determine the cell toxicity of these plant extracts, MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay was used. MTT assay experiment showed that Carlemannia tetragona Hook. f., and Celastrus virens might have less toxicity 23.3% and 27.5%, respectively, compared to control. Taken together, these experiments showed that Celastrus virens extracts might have much higher antioxidant activities than Carlemannia tetragona Hook. f., with relatively lower toxicity. This implies that this study might provide a basis to develop a new powerful antioxidant candidate for human diseases therapeutics.

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Studies on Anti-inflammatory Activities of Extracts from Manglietia insignis and Tirpitzia sinensis

  • Oh, Hyun-Jee;Lee, Sang-Soo;Kim, June-Hyun
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.10a
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    • pp.79-79
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    • 2019
  • The aim of the study was to determine the antioxidant activities of the plants with origin of Vietnam. The Manglietia insignis (Wall.) Blume, which is a species of plant in the family Magnoliaceae and Tirpitzia sinensis (Hemsl.) Hallier f., which is a species of plant in the family Linaceae were tested for antioxidant activities. Samples were prepared using 95% ethanol using Nitric Oxide (NO) assay for assessing the anti-inflammatory activity. NO assay experiment showed that extracts of the Manglietia insignis (Wall.) Blume and Tirpitzia sinensis (Hemsl.) Hallier f. might have the 36.2% more anti-inflammatory activity and 59.5% more anti-inflammatory activity, respectively, compared to control. To determine the cell toxicity, MTT (3-(4,5-dimethylthiazol-2-yl) -2,5-diphenyltetrazolium bromide) assay was used. MTT assay experiment showed that the Manglietia insignis (Wall.) Blume and Tirpitzia sinensis (Hemsl.) Hallier f. might have the 31.0% less toxicity and 8.52% more toxicity, respectively, compared control. Taken together, these experiments showed that Manglietia insignis (Wall.) Blume extracts might have significantly higher anti-inflammatory activities and relatively lower toxicity, compared to control.

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Single Nucleotide Polymorphism in Patients with Moyamoya Disease

  • Park, Young Seok
    • Journal of Korean Neurosurgical Society
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    • v.57 no.6
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    • pp.422-427
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    • 2015
  • Moyamoya disease (MMD) is a chronic, progressive, cerebrovascular occlusive disorder that displays various clinical features and results in cerebral infarct or hemorrhagic stroke. Specific genes associated with the disease have not yet been identified, making identification of at-risk patients difficult before clinical manifestation. Familial MMD is not uncommon, with as many as 15% of MMD patients having a family history of the disease, suggesting a genetic etiology. Studies of single nucleotide polymorphisms (SNPs) in MMD have mostly focused on mechanical stress on vessels, endothelium, and the relationship to atherosclerosis. In this review, we discuss SNPs studies targeting the genetic etiology of MMD. Genetic analyses in familial MMD and genome-wide association studies represent promising strategies for elucidating the pathophysiology of this condition. This review also discusses future research directions, not only to offer new insights into the origin of MMD, but also to enhance our understanding of the genetic aspects of MMD. There have been several SNP studies of MMD. Current SNP studies suggest a genetic contribution to MMD, but further reliable and replicable data are needed. A large cohort or family-based design would be important. Modern SNP studies of MMD depend on novel genetic, experimental, and database methods that will hopefully hasten the arrival of a consensus conclusion.

A New Record of the Pacific Sleeper Shark, Somniosus pacificus (Squaliformes: Somniosidae) from the Western Margin of the East Sea, Korea (한국산 Somniosidae 어류 1 미기록종, Somniosus pacificus)

  • Kang, Chung-Bae;Lee, Woo Jun;Kim, Jin-Koo;Jung, Hye Gyeong
    • Korean Journal of Ichthyology
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    • v.27 no.1
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    • pp.45-49
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    • 2015
  • A single specimen (192 cm total length, TL) of the Pacific sleeper shark, Somniosus pacificus, belonging to the family Somniosidae, order Squaliformes, was firstly collected from the west margin of the East Sea, Korea in February 2008. This specimen was characterized by having interdorsal space, being less than the distance between the snout and first gill opening; and the distance between the snout and first dorsal fin origin more than 45% TL; head and body has overall dark brownish. The new Korean name "Jam-sang-eo-gwa" is proposed for the family Somniosidae, and "Jam-sang-eo-sok" for the genus Somniosus, and "Jat-bit-jam-sang-eo" for the species S. pacificus.