• The Korean Journal of Elementary Counseling
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• v.11 no.3
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• pp.427-446
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• 2012

The purpose of this study was to investigate the influence of stress in families of children with disabilities upon a problem-solving ability based on a buffering effect of family resilience through life cycle. To achieve this purpose, the subjects in this study was 546 parents who have kindergarten, elementary, middle & high school students in special schools. The date for this study were derived from questionaries and the answer sheet was analyzed by SPSS(VER. 14). A descriptive statistics, correlation analysis, hierarchical moderating regression analysis were used to investigate the general information and the difference of perception between groups. The findings of this study were as follows: Higher belief system, higher organization type, higher communication process of the family with disabled children tend to appear more positive influences on buffering effects for stresses of family and solving-problem abilities. Findings from the current study demonstrate that the buffering effect of family resilience indicate to have positive influences on the relationship between the stress and the problem-solving ability in the family with disabled children.

• Journal of the Korean Home Economics Association
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• v.20 no.1
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• pp.65-77
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• 1982

The intent of this study was to focus attention on the relationship between curtain fabrics and consumer perceptions towards curtains and draperies. This study consisted of the laboratory test for thermal transmittance of selected fabrics and the exploratory survey for consumer perceptions towards curtains and draperies. The objectives of the laboratory test were to measure fabric's thermal transmittance, thickness, and count which affect to the effect in heat controlling. Selected 23 fabrics were tested at Korean Yarn and Fabrics Testing Inspection Institute. The objectives of the exploratory survey were to determine sociodemographic factors; the stage of family life cycle, the economics status, and homemaker's level of education, and physical factors; the type of houses, the direction of windows, and the type of windows, affect consumer perceptions toward curtains and draperies. Questionaires were administered to 489 homemakers selected by a stratified propotional sampling plan, in Seoul in October, 1981. Data from responses were analyzed by T-test(Analysis of Varience) and Partial Correlation. The major findings are as follows; 1. The results of the laboratory test 1) The fabrics used for draperies had higher effect in heat controlling than the fabrics used for glass curtains. 2) It did not show much differences among the fibers in heat controlling. The thicker fibers, however, had the higher effect in heat controlling among same fibers. 3) The fabrics which had high level of effect I heat controlling were corduroy, flax, rayon, nylon, acetate, thick polyester, and thick polyacrylic. The fabrics which had midium level of affect in heat controlling were velveteen, velvet, and thin polyester. The fabrics which had low level of effect in heat controlling were cotton, silk, and thin polyarcylic. 4) The draperies with lining showed 2∼5 times more effective in heat controlling than the draperies without lining. 2. The results of the exploratory survey Consumer perceptions towards curtains and draperies consisted of functional, financial, and aesthetic perception. 1) Factor affecting functional perception towards curtains and draperies was the stage of family life cycle. Families in the contracting stage considered function of curtains and draperies significantly better than those in others stages. 2) Factors affecting financial perception towards curtains and draperies were the economic status, homemaker's level of education, the direction of windows, and the type of windows. However the correlation between the factors and financial perception was too low to explain the significance of tendency. 3) There was not any factors affecting aesthetic perception towards curtains and draperies.

• Korea journal of population studies
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• v.14 no.1
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• pp.55-69
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• 1991

The objective of the study is to figure out the status of reproductive health and general characteristics related to maternal health for Korean-Americans living in Los Angeles. We collected data from the married women who wanted no more additional child birth and were attending the Family Planning Clinic of Koryo Health Foundation in Los Angeles during 1988. There were 494 women met the eligibility requirement for this study. The results are summarized below. 1. In the age distribution of the women who desired no more additional child birth, women 30-34 age group constituted the largest proportion at 36.6 percent ; the mean age of women was 35.1915.55. The mean number of child birth was 1.77, and the proportion of the women by number of child birth were 35.2 percent for one children, 50.1 percent for two children 10.5 percent for three children, and 2.6 percent for four children. All of the women experienced pregnancy at least once, and mean number of pregnancy was 3.42. The mean number of total experience of induced abortion was 1.56. and 76.7 percent of these women had experience with induced abortions. To prevent further pregnancies, 90.1 percent of the women were utilizing the contraceptive methods, and the highest proportion by the contraceptive methods was condoms(53.7%), 9.3 percent in spermicides, 8.7 percent in IUDs, 8.7 percent in rhythm method, and 6.9 percent in oral pills. 2. The mean age of women at each stage of reproductive life cycle were 14.74 years at time of menarche, 24.55 years at time of marriage, 26.60 years at time of the first child birth, and 28.75 years at time of the last child birth. In age distribution of the women by birth cohort (Group I : birth cohort 1940-1954, Group H : birth cohort 1955-1970), the mean menar-cheal age of the women was 14.96 years in group I , and 14.53 years in group H . Mean age at time of marriage was 25.01 years in group I and 24.08 years in group H . Mean child birth age of the women by birth cohort was 27.19 years In group I and 26.01 years in Group II for the first child birth and 30.07 years in group I and 27.45 years in group II for the last child birth. The total length of reproductive life cycle from menarche to menopause (presumed to be at 49 of age years) was 34.26 years. The len-gth of phase I (from menarche to marriage) was 9.81 years, while phase H (marriage to first birth) was 2.05 years, and phase Ill (first birth to last birth) was 2. 15 years, and the last phase of reproductive life cycle, phase IV (last birth to menopause) was 20.25 years. The proportion of each phase 10 total length of reproductive life cycle was 28.6 percent, 6.0 percent 6.3 percent, and 59.t percent respectively. In the tendency of each phase in reproductive life cycle by birth cohort (group I , U ), the length of phase I, II , III of birth cohort group II was diminished in comparison with those of birth cohort group I , but the length of phase IV was extended by 2.38 years. 3. Among the women, the mean number of total pregnancy by birth cohort group was 2.01 in group I and 1.10 in Group II, and mean number of child birth was 1.97 in group I and 1.58 in group II. In terms of pregnancy was-tage rate by birth cohort group, among the total pregnancy of birth cohort group I , 51.8 percent of the cases resulted in induced abortions or spontaneous abortions whils 48.2 percent resulted in live births, and 42.2 percent or total pregnancy in group II resulted in pregnancy wastage and 57.8 percent of the cases resulted in live births.

• Journal of Life Science
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• v.25 no.1
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• pp.1-7
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• 2015

Cyclin D is a member of the cyclin protein family, which plays a critical role as a core member of the mammalian cell cycle machinery. D-type cyclins (D1, D2, and D3) bind to and activate the cyclin-dependent kinases 4 and 6, which can then phosphorylate the retinoblastoma tumor suppressor gene products. This phosphorylation in turn leads to release or derepression of E2F transcription factors that promote progression from the G1 to S phase of the cell cycle. Among the D-type cyclins, cyclin D3 encoded by the CCND3 gene is one of the least well studied. In the present study, we have investigated the biochemistry of the proteolytic mechanism that leads to loss of cyclin D3 protein. Treatment of human prostate carcinoma PC-3-M cells with lovastatin and actinomycin D resulted in a loss of cyclin D3 protein that was completely reversible by the peptide aldehyde calpain inhibitor, LLnL. Additionally, using inhibitors for various proteolytic systems, we show that degradation of cyclin D3 protein involves the $Ca^{2+}$-activated neutral protease calpain. Moreover, the half-life of cyclin D3 protein half-life increased by at least 10-fold in PC-3M cells in response to the calpain inhibitor. We have also demonstrated that the transient expression of the calpain inhibitor calpastatin increased cyclin D3 protein in serum-starved NIH 3T3 cells. These data suggested that the function of cyclin D3 is regulated by $Ca^{2+}$-dependent protease calpain.

• Journal of Mechanical Science and Technology
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• v.19 no.10
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• pp.1919-1931
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• 2005

Human joint motion can be kinematically described in three planes, typically the frontal, sagittal, and transverse, and related to experimentally measured data. The selection of reference systems is a prerequisite for accurate kinematic analysis and resulting development of the equations of motion. Moreover, the development of analysis techniques for the minimization of errors, due to skin movement or body deformation, during experiments involving human locomotion is a critically important step, without which accurate results in this type of experiment are an impossibility. The traditional kinematic analysis method is the Angular-based method (ABM), which utilizes the Euler angle or the Bryant angle. However, this analysis method tends to increase cumulative errors due to skin movement. Therefore, the objective of this study was to propose a new kinematic analysis method, Position-based method (PBM), which directly applies position displacement data to represent locomotion. The PBM presented here was designed to minimize cumulative errors via considerations of angle changes and translational motion between markers occurring due to skin movements. In order to verify the efficacy and accuracy of the developed PBM, the mean value of joint dislocation at the knee during one gait cycle and the pattern of three dimensional translation motion of the tibiofemoral joint at the knee, in both flexion and extension, were accessed via ABM and via new method, PBM, with a Local Reference system (LRS) and Segmental Reference system (SRS), and then the data were compared between the two techniques. Our results indicate that the proposed PBM resulted in improved accuracy in terms of motion analysis, as compared to ABM, with the LRS and SRS.

• Journal of Life Science
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• v.18 no.3
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• pp.336-343
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• 2008

Histone deacetylases (HDACs) inhibitors have emerged as the accessory therapeutic agents for various human cancers, since they can block the activity of specific HDACs, restore the expression of some tumor suppressor genes and induce cell differentiation, cell cycle arrest and apoptosis in vitro and in vivo. In the present study, we investigated that the effect of trichostatin A (TSA), an HDAC inhibitor, on the cell growth and apoptosis, and its effect on the nuclear factor-kappaB $(NF-{\kappa}B)$ activity in 267B1 human prostate epithelial cells. Exposure of 267B1 cells to TSA resulted in growth inhibition and apoptosis induction in and dose-dependent manners as measured by fluorescence microscopy, agarose gel electrophoresis and flow cytometry analysis. TSA treatment inhibited the levels of IAP family members such as c-IAP-1 and c-IAP-2 and induced the proteolytic activation of caspase-3, -8 and -9, which were associated with concomitant degradation of poly (ADP-ribose)-polymerase, ${\beta}-catenin$ and laminin B proteins. The increase in apoptosis by TSA was connected with the translocation of $NF-{\kappa}B$ from cytosol to nucleus, increase of the DNA binding as well as promoter activity of $NF-{\kappa}B$, and degradation of cytosolic inhibitor of KappaB $(I{\kappa}B)-{\alpha}$ protein. We therefore concluded that TSA demonstrated anti-proliferative and apoptosis-inducing effects on 267B1 cells in vitro, and that the activation of caspases and $NF-{\kappa}B$ may play important roles in its mechanism of action. Although further studies are needed, these findings provided important insights into the possible molecular mechanisms of the anti-cancer activity of TSA.

• Journal of the Korean Home Economics Association
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• v.31 no.1
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• pp.97-120
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• 1993

This study is designed to understand marital relationships of the rural couples in Korea. The primary purposes of this study are to examine the relationship between marital satisfaction and role evaluation of the spouse and to construct a path model in which shows the relationships among background variables, role evaluation of the spouse and marital satisfaction. Structured guestionnaires from 435 couples with school-age children and teenagers living in rural area are analyzed in this study. The major findings are as follows : 1. Factor analysis of the role evaluation of the spouse results I 4 factors for both husbands and wives; emotional support-sexual role child socialization-economic role, kinship role and housekeeping role. 2. The most important factor influencing the marital satisfaction is the role evaluation of the spouse o emotional support-sexual relation. While the number of children, and role evaluations of the spouse influence directly on the marital satisfaction of the wives, age, level of education, level of income and husband's occupation influence indirectly through role evaluations of the spouse on that of wives. 3. For husbands, family life cycle and their occupation influence indirectly on the marital satisfaction of the husbands and the marital satisfaction of them is also mediated by role evaluations of the wieves. Level of income of the family not only influences directly on marital satisfaction but influences on it indirectly. 4. Marital satisfaction is mediated by role evaluations of the spouse. The role evaluation of the spouse on emotional support-sexual relation has the most powerful effect on the marital satisfaction for both wives and husbands. About 60 percent of the variance in the marital satisfaction of rural couples can be explained by the role evaluation of the spouse. therefore, the result of the result of the study indicates that the role evaluation of the spouse on emotional support-sexual relation plays a significant part in determining the marital satisfaction of rural couples.

• Korean Journal of Social Welfare
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• v.69 no.2
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• pp.117-141
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• 2017

The purpose of this study is to investigate the differences of the factors affecting the entry of depression by generations and to present a practical strategy for preventing of depression by life-cycle. For this purpose, we analyzed the factors influencing the depression of adults, middle-aged and elderly people through the discrete-time hazard model. The results of this study are as follows: First, the lower the self-esteem, the lower the income satisfaction and the family satisfaction people have, the higher the likelihood of entering the depression they have. In addition, age, educational level, health status, presence of chronic diseases, employment status, regional area, and leisure life satisfaction were variables that showed difference by generation. In the case of adulthood(aged 20 ~ 39), unemployed persons are more likely to enter the depression than younger workers. On the other hand, the middle-aged(40 ~ 64 year olds) are more likely to enter the depression if they are older, have poor health status, have no chronic disease, and have low leisure satisfaction. Finally, older people(aged 65 and over) are more likely to enter the depression when the education level is higher, the health condition is worse, and the leisure satisfaction is lower. If they lived in an urban and rural complex, they are more likely to enter the depression. Based on these results, it is necessary to establish a support plan reflecting the characteristics revealed by generations in order to prevent the entry of depression.

• Journal of the Korean housing association
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• v.10 no.2
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• pp.223-234
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• 1999

The purpose of this study was to provide basic information for future residential flooring planning by identifying differences in preference for flooring materials of livingroom by characteristics of housewives living in apartment housing and by describing their perception of residential flooring materials and by analyzing their degree of satisfaction with the current flooring materials of livingroom. For this purpose, a survey was conducted by 281 housewives who lives in apartment, and analyzed by using frequency, percentage, mean, factor analysis, χ² test, t-test, one-way ANOVA and Duncan's Multiple Range test. The results of the study were obtained as follows: 1) The most preferred flooring materials was wood in the livingroom. Also, most of the reasons for preferred this flooring materials were good for health and good texture. 2) As a result of typifying housewives' perceptions of residential flooring materials, it was classified into fashoin-pursuit type, personality-expression type, beauty-pursuit type, health-pursuit type and practicality-pursuit type. 3) In the degree of satisfaction with the current flooring materials of livingroom, wood showed the highest level of satisfaction. 4) Differences in the degree of satisfaction with the current flooring materials of livingroom by personal characteristics of residents were analyzed. As results, it was found that the group who were later stage of family life cycle and experienced in replacing the flooring materials showed higher degree of satisfaction with the current flooring materials of livingroom.

• Journal of the Korean Institute of Rural Architecture
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• v.17 no.4
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• pp.57-65
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• 2015

In contrast to apartments, detached houses offer the possibility of more than one entrance connecting interior and exterior spaces. This study examines the location, function, and use of second doors in detached houses in rural areas. The study employs survey and interviews conducted in 2015, focusing on 18 detached houses among 40 houses previously surveyed in 1995. In 1995, 21 second doors were found, while in 2015, 19 were found. The study led to the following conclusions. First, most houses did have second doors installed by 1995 or 2015. Second doors tended to be installed in kitchen and utility rooms. The function of second doors was most closely connected to the kitchen because utility rooms were placed adjacent to kitchens. Secondly, changes in the use and number of second doors were changes in family life cycle and composition, the need for new equipment facilities, the use of new architectural materials, and the installation of new second doors for extension of space. Finally, exterior spaces accessed by second doors tend to be a meeting of semi-interior or semi-exterior space and exterior space only. Those spaces tended to be designed for kitchen fixtures or to support kitchen activities.