• Title/Summary/Keyword: failure stage

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The Failure of Initial Treatment for TNM Stage I & II Squamous Cell Carcinomas of the Oral Cavity (조기(TNM Stage I & II) 구강 편평세포암종의 초치료 실패)

  • Lee Hyun-Seok;Jeong Han-Sin;Kim Tae-Wook;Son Young-Ik;Baek Chung-Hwan
    • Korean Journal of Head & Neck Oncology
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    • v.21 no.1
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    • pp.26-31
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    • 2005
  • Backgrounds and Objectives: Squamous cell carcinomas of the oral cavity(SCOC) in TNM stage I & II have relatively high chance to be cured compared to those in the advanced stage, but sometimes result in the treatment failure with poor prognosis. There have been few reports on the patterns of failure and the clinical courses for SCOC in stage I & II after the failure of initial treatment. This study is directed at identifying the clinical outcomes of stage I & II SCOC and the salvage rate after initial treatment and suggesting an optimal level of treatment by analyzing the patterns of failure. Material and Methods: The medical records of 36 patients with SCOC, initially diagnosed between 1995 and 2001 as TNM stage I & II were reviewed retrospectively. The patterns of failure, salvage treatment, clinical courses, and the survival of these subjects were analyzed. The minimum follow-up period of no-evidence of disease(NED) was 12 months with an average of 32.2 months. Results: Overall rate of the treatment failure in SCOC of stage I & II was 41. 7%(15/36 cases). Most of the treatment failure in the subjects with stage I tumors occurred in regional lymph node. Local failure was the most frequent form of failure in the subjects with stage II tumors after wide excision of primary tumor with elective neck dissection and/or radiation therapy. No significant correlation was noted between the safety margin and the local failure. Elective neck dissections in stage I & II SCOC had a tendency to reduce regional failure (p=0.055). The salvage rates at 24 months were 85.7% in stage I, and 37.5% in stage II. The 3-year survival rate after the failure of initial treatment was 55.0%. Conclusion: SCOC of stage I & II after the failure of initial treatment showed poor prognosis despite of the salvage treatments. This study implies that the elective neck dissections for regional lymph node should be required for SCOC of stage I & II to reduce the treatment failure.

Visualization analysis of the progressive failure mechanism of tunnel face in transparent clay

  • Lei, Huayang;Zhai, Saibei;Liu, Yingnan;Jia, Rui
    • Geomechanics and Engineering
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    • v.29 no.2
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    • pp.193-205
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    • 2022
  • The face stability of shield tunnelling is the most important control index for safety risk management. Based on the reliability of the transparent clay (TC) model test, a series of TC model tests under different buried depth were conducted to investigate the progressive failure mechanism of tunnel face. The support pressure was divided into the rapid descent stage, the slow descent stage and the basically stable stage with company of the local failure and integral failure in the internal of the soil during the failure process. The relationship between the support pressure and the soil movement characteristics of each failure stage was defined. The failure occurred from the soil in front of the tunnel face and propagated as the slip zone and the loose zone. The fitted formulas were proposed for the calculation of the failure process. The failure mode in clay was specified as the basin shape with an inverted trapezoid shape for shallow buried and appeared as the basin shape with a teardrop-like shape in deep case. The implications of these findings could help in the safety risk management of the underground construction.

A Two-stage Reliability Demonstration Test for Mechanical Components (기계류부품 신뢰성보증을 위한 2단계 시험방식 설계)

  • Kwon, Young-Il
    • Journal of Korean Society for Quality Management
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    • v.34 no.1
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    • pp.20-26
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    • 2006
  • In the fields of mechanical reliability application, "zero" or "zero or one" failure tests are most commonly used for demonstrating reliability of a product since they reduce test duration and/or sample size compared to other test methods that guarantees the same reliability of a product with a given confidence level or consumer's risk. The test duration of the "zero or one" failure test is longer than that of "zero" failure test but it has advantage of smaller producer's risk. In this paper a two-stage test is developed that compromises the "zero" and "zero or one" failure tests. The properties of the proposed two-stage test are investigated and the three test methods are compared using a numerical example.

Overtopping Model Experiments and 3-D Seepage Characteristics of the Embankment of Deteriorated Homogeneous Reservoirs (노후화된 균일형 저수지 제체의 월류모형실험과 3차원 침투특성)

  • Lee, Young Hak;Lee, Tae Ho;Lee, Dal Won
    • Journal of The Korean Society of Agricultural Engineers
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    • v.61 no.2
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    • pp.13-23
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    • 2019
  • In this study, an overtopping model experiments and three dimensional seepage characteristics at the deteriorated homogeneous reservoirs were performed to investigate the behavior of failure for embankment and spillway transitional zone due to overtopping. The failure pattern, pore water pressure, earth pressure and settlement by overtopping were compared and analyzed. The pattern of the failure by overtopping was gradually enlarged towards reservoirs crest from the spillway transition zone at initial stage. In the rapid stage and peak stage, the width and depth of failure gradually increased, and the pattern of the failure appeared irregular and several direction of the erosion. In the early stage, the pore water pressure at spillway transitional zone was more affected as its variation and failure width increased. In the peak stage, the pore water pressure was significantly increased in all locations due to the influence of seepage. The earth pressure increased gradually according to overtopping stage. The pore pressure by the numerical analysis was larger than the experimental value, and the analysis was more likely to increase steadily without any apparent variation. The horizontal and vertical displacements were the largest at the toe of slope and at the top of the dam crest, respectively. The results of this displacement distribution can be applied as a basis for determining the position of reinforcement at the downstream slope and the crest. The collapse in the overtopping stage began with erosion of the most vulnerable parts of the dam crest, and the embankment was completely collapsed as the overtopping stage increased.

Development of the 'Three-stage' Bayesian procedure and a reliability data processing code (3단계 베이지안 처리절차 및 신뢰도 자료 처리 코드 개발)

  • 임태진
    • Korean Management Science Review
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    • v.11 no.2
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    • pp.1-27
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    • 1994
  • A reliability data processing MPRDP (Multi-Purpose Reliability Data Processor) has been developed in FORTRAN language since Jan. 1992 at KAERI (Korean Atomic Energy Research Institute). The purpose of the research is to construct a reliability database(plant-specific as well as generic) by processing various kinds of reliability data in most objective and systematic fashion. To account for generic estimates in various compendia as well as generic plants' operating experience, we developed a 'three-stage' Bayesian procedure[1] by logically combining the 'two-stage' procedure[2] and the idea for processing generic estimates[3]. The first stage manipulates generic plant data to determine a set of estimates for generic parameters,e.g. the mean and the error factor, which accordingly defines a generic failure rate distribution. Then the second stage combines these estimates with the other ones proposed by various generic compendia (we call these generic book type data). This stage adopts another Bayesian procedure to determine the final generic failure rate distribution which is to be used as a priori distribution in the third stage. Then the third stage updates the generic distribution by plant-specific data resulting in a posterior failure rate distribution. Both running failure and demand failure data can be handled in this code. In accordance with the growing needs for a consistent and well-structured reliability database, we constructed a generic reliability database by the MPRDP code[4]. About 30 generic data sources were reviewed and available data were collected and screened from them. We processed reliability data for about 100 safety related components frequently modeled in PSA. The underlying distribution for the failure rate was assumed to be lognormal or gamma, according to the PSA convention. The dependencies among the generic sources were not considered at this time. This problem will be approached in further study.

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A Study on FMEA for Railway Vehicle (철도차량의 고장모드 영향분석(FMEA))

  • Park, Byoung-Noh;Joo, Hae-Jin;Lee, Chang-Hwan;Lim, Sung-Soo
    • Proceedings of the KSR Conference
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    • 2009.05a
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    • pp.162-168
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    • 2009
  • FMEA(Failure Mode and Effect Analysis) is a failure analysis method for the system to identify the potential failure modes, and their effects and causes to reduce or mitigate the critical effects of the system. FMEA for railway was introduced with reliability of railway system, and this was used for identifying and analysing the possible hazards qualitatively to meet the requirements in early stage of business. In general, the overall failure data of system could be managed from design stage by FMEA, and also the countermeasures to prevent many predicted failures could be established by identification of failure modes and assement of failure effects by FMEA. Using these advantages of FMEA, the effectiveness of reliability improvement could be expected if FMEA is applied continuously in operation stage. It is essential that railway vehicles are maintained with high level of safety and reliability not to happen any failures in operation. This paper is proposed the proper FMEA for maintenance of railway vehicles compared with existing FMEA.

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Reliability Analysis and Reliability Modeling for KSLV-I Upper Stage (KSLV-I 상단부에 대한 신뢰성 분석과 신뢰도 모델링)

  • Shin, Myoung-Ho;Cho, Sang-Yeon
    • Aerospace Engineering and Technology
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    • v.7 no.1
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    • pp.183-193
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    • 2008
  • This paper shows the results of failure mode analysis and the system-level reliability model for the flight test of KSLV-I upper stage. First, the critical 14 functions of KSLV-I upper stage are identified and the mission profile of the flight test is analyzed. Then, based on the functional analysis and the mission profile analysis, we construct a hierarchical structure of failure modes and a system-level reliability model for the flight test of KSLV-I upper stage.

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Cancinoma of Uterine Cervix Treated wvith High Dose Rate Intracavitary Irradiation : 1 Patterns of Failure (자궁경부암의 고선량율 강내치료후 실패양상에 대한 고찰)

  • Kim Ok Bae;Choi Tee Jin;Kim Jin Hee;Lee Ho Jun;Kim Yung Ae;Suh Young Wook;Lee Tae Sung;Cha Soon Do
    • Radiation Oncology Journal
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    • v.11 no.2
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    • pp.369-376
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    • 1993
  • 226 patients with carcinoma of the uterine cervix treated with curative radiation therapy at the Department of Therapeutic Radiology, Dongsan hospital, Keimyung university, School of medicine, from July,1988 to May,1991 were evaluated. The patients with all stages of the disease were included in this study. The maximum and mean follow up durations were 60 and 43 months. The radiation therapy consisted of external irradiation to the whole pelvis (2700~4500 cGy) and boost parametrial doses (for a total of 4500~6300 cGy)with midline shild $(4{\times}10\;cm),$ and combined with intracavitary irradiation (5700~7500 cGy to point A). The distribution of patients according to the stage was as follows: stage IB 37 $(16.4\%),$ stage IIA 91 $(40.3\%),$ stage IIB 58 $(25.7\%),$ stage III 32 $(13.8\%),$ stage IV 8 $(3.5\%).$ The overall failure rate was $23.9\%$ (54 patients). The failure rate increased as a function of stage from $13.5\%$ in stage IB to $15.4\%$ in stage IIA, $25.9\%$ in stage IIB, $46.9\%$ in stage III, and $62.5\%$ in stage UV. The pelvic failure alone were 32 patients and 11 patients were as a components of other failure, and remaining 11 patients had distant metastasis only. Among the 43 patients of locoregional failure,28 patients were not controlled initially and in other words nearly half of total failures were due to residual tumor. The mean medial paracervical (point A) doses were 6700 cGy in stage IIB,7200 cGy in stage IIA,7450 cGy in stage IIB,7600 cGy in stage III and 8100 cGy in stage IV. The medial paracervical doses showed some correlation with tumor control rate in early stage of disease (stage Ib, IIA), but there were higher central failure rate in advanced stage in spite of higher paracervical doses. In advanced stage, failure were not reduced by simple increment of paracervical doses. To improve a locoregional control rate in advanced stages, it is necessary to give additional treatment such as concomitant chemoradiation.

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The Video on Demand System Failure Evaluation of Software Development Step

  • Jang, Jin-Wook
    • Journal of the Korea Society of Computer and Information
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    • v.24 no.4
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    • pp.107-112
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    • 2019
  • Failure testing is a test that verifies that the system is operating in accordance with failure response requirements. A typical failure test approaches the operating system by identifying and testing system problems caused by unexpected errors during the operational phase. In this paper, we study how to evaluate these Failure at the software development stage. Evaluate the probability of failure due to code changes through the complexity and duplication of the code, and evaluate the probability of failure due to exceptional situations with bugs and test coverage extracted from static analysis. This paper studies the possibility of failure based on the code quality of software development stage.

Design of Direct-Current Fuzzy Controller for Mitigating Commutation Failure in HVDC System

  • Gao, Benfeng;Yuan, Kewei;Dong, Peiyi;Luo, Chao;Zhao, Shuqiang
    • Journal of Electrical Engineering and Technology
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    • v.13 no.4
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    • pp.1450-1458
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    • 2018
  • Commutation failures can deteriorate the availability of high-voltage direct current (HVDC) links and may lead to outage of the HVDC system. Most commutation failures are caused by voltage reduction due to ac system faults on inverter side. The commutation failure process can be divided into two stages. The first stage, from the occurrence to the clearing of faults, is called 'Deterioration Stage'. The second stage, from the faults clearing to restoring the power system stability, is called 'Recovery Stage'. Based on the analysis of the commutation failure process, this paper proposes a direct-current fuzzy controller including prevention and recovery controller. The prevention controller reduces the direct current to prevent Commutation failures in the 'Deterioration Stage' according to the variation of ac voltage. The recovery controller magnifies the direct current to speed up the recovery of power system in the 'Recovery Stage', based on the recovery of direct voltage. The validity of this proposed fuzzy controller is further proved by simulation with CIGRE HVDC benchmark model in PSCAD/EMTDC. The results show the commutation failures can be mitigated by the proposed direct-current fuzzy controller.