• Journal of Biomedical Engineering Research
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• v.24 no.6 s.81
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• pp.515-522
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• 2003

Pharynx is a system transporting foods by peristaltic motion(contraction and expansion movement! into the esophagus and functioning as airway passages. In this study, structural changes of pharyngeal dysfunction are analyzed by biomechanical model using CT and FEM(finite clement method). Loading condition was assumed that equal pressure was loaded sequentially to inside of pharyngeal tissue. In order to analyze the pharyngeal muscular dysfunction by biomechanical model. the pharyngeal dysfunctions was classified into 3 cases. Taking into account the clinical complication by neuromuscular symptoms such as pharyngeal dysfunction after stroke. we assumed that a change of material property is caused by muscular tissue stiffness. A deformation of cross sectional area of the pharynx is analyzed increasing the stiffness $25\%,\;50\%,\;75\%$ in each case on the basis of stress-strain relationship. Based on three-dimensional reconstruction of pharyngeal structure using limited factor - techniques and the optimization procedure by means of inverse dynamic approach. the biomechanical model of the human pharynx is implemented. The results may be used as clinical index illustrating the degree of pharyngeal muscular dysfunction. This study may be used as useful diagnostic model in discovering early deglutitory impediment caused by physiological or pathological pharyngeal dysfunction.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.1
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• pp.17-27
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• 2019

In this paper, we study the applicability of Tuned Mass Damper(TMD) to improve seismic performance of piping system under earthquake loading. For this purpose, a mode analysis of the target pipeline is performed, and TMD installation locations are selected as important modes with relatively large mass participation ratio in each direction. In order to design the TMD at selected positions, each corresponding mode is replaced with a SDOF damped model, and accordingly the corresponding pipeline is converted into a 2-DOF system by considering the TMD as a SDOF damped model. Then, optimal design values of the TMD, which can minimize the dynamic amplification factor of the transformed 2-DOF system, are derived through GA optimization method. The proposed TMD design values are applied to the pipeline numerical model to analyze seismic performance with and without TMD installation. As a result of numerical analyses, it is confirmed that the directional acceleration responses, the maximum normal stresses and directional reaction forces of the pipeline system are reduced, quite a lot. The results of this study are expected to be used as basic information with respect to the improvement of the seismic performance of the piping system in the future.

• The Journal of Korean Obstetrics and Gynecology
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• v.34 no.1
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• pp.1-14
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• 2021

Objectives: We studied for the adjustment of the patterns of 'The Diagnostic Tool for Climacteric and Postmenopausal Syndrome Pattern Identification (hereinafter CaPSPI)' (studyI) and the correlation between CaPSPI and Korean medicine doctors' diagnosis which was carried out without knowing the results of CaPSPI (studyII). Methods: The studyI followed the previous study method in 2018 (2018-3). The studyII was conducted from June 1, 2019 to July 10, 2020 with ◯◯ University Korean Medicine Hospital IRB's approval (2019-4). Doctors' diagnosis was conducted face-to-face with the subjects. Doctors' diagnosis was carried out based on the Kupperman's questionnaire, 'Diagnosis System of Oriental Medicine (hereinafter DSOM)' and four examinations (四診) records. The diagnosis was marked with 0 for 'no', 1 for 'somewhat', 2 for 'yes' and 3 for 'very yes'. The correlation between CaPSPI and the mean of doctors diagnostic scores were investigated statistically. Results: The studyI showed that heart-heat (心火) pattern was added. The Factor loading coefficient for heart-heat was 0.551 to 0.789, and the Cronbach's coefficient was 0.896. The studyII showed that the diagnosis (Kappa statistic) of two doctors showed statistically significant concordance (all eight patterns), with correlation of them were 0.3 or higher. And the correlation between the CaPSPI score and the mean of doctors' diagnostic score showed a statistically significant correlation, with liver qi depression (肝鬱) being the highest at 0.552 and dual deficiency of the heart-spleen (心脾兩虛) being the lowest at 0.301. Conclusions: Since the diagnosis results of CaPSPI showed a significant correlation with the diagnosis of Korean traditional medicine experts, it was believed that the CaPSPI results can be trusted and used for clinical purposes.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.33 no.6
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• pp.287-292
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• 2021

Load and resistance factor design is an efficient design approach that provides a system of consistent design solutions. This study aims to determine the load and resistance factors needed for the design of breakwater foundations within a probabilistic framework. In the study, four typical types of Korean breakwaters, namely, rubble mound breakwaters, vertical composite caisson breakwaters, perforated caisson breakwaters, and horizontal composite breakwaters, are investigated. The bearing capacity of breakwater foundations under wave loading conditions is thoroughly examined. Two levels of the target reliability index (RI) of 2.5 and 3.0 are selected to implement the load and resistance factors calibration using Monte Carlo simulations with 100,000 cycles. The normalized resistance factors are found to be lower for the higher target RI as expected. Their ranges are from 0.668 to 0.687 for the target RI of 2.5 and from 0.576 to 0.634 for the target RI of 3.0.

• Korean Journal of Food Science and Technology
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• v.53 no.4
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• pp.479-485
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• 2021

To improve the oxidative stability of Glycyrrhiza uralensis extract (GU), GU extraction conditions were optimized for maximal antioxidant activity, and GU-loaded nanocapsules were prepared by chitosan ionic gelation. The optimized ethanol concentration and extraction time were 83.0% and 32.6 min, respectively, using response surface methodology. The particle size of the GU-loaded nanocapsules ranged from 280 to 370 nm. A GU extract of 0.8 mg/mL and chitosan concentration of 2.0 mg/mL were selected as the optimal conditions for entrapment and loading efficiency. Both free GU and GU-loaded chitosan nanocapsules exhibited concentration-dependent antioxidant activity. However, the antioxidant protection factor of GU was effectively maintained when it was entrapped within the chitosan nanocapsules. In conclusion, chitosan nanoencapsulation is a potentially valuable technique for improving the oxidative stability of GU.

• Journal of the Korea Society for Simulation
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• v.32 no.3
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• pp.93-108
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• 2023

In manufacturing productivity analysis, understanding the intricate interplay among factors like facility performance, layout design, and workforce allocation within the production line is imperative. This paper introduces a simulation-based methodology tailored to food manufacturing, progressively expanding scenarios to analyze production enhancement. The target system is a food processing plant, encompassing production processes, including warehousing, processing, subdivision, packaging, inspection, loading, and storage. First, we analyze the target system and design a simulation model according to the actual layout arrangement of equipment and workers. Then, we validate the developed model reflecting the real data obtained from the target system, such as the workers' working time and the equipment's processing time. The proposed model aims to identify optimal factor values for productivity gains through incremental scenario comparisons. To this end, three stages of simulation experiments were conducted by extending the equipment and worker models of the subdivision and packaging processes. The simulation experiments have shown that productivity depends on the placement of skilled workers and the performance of the packaging machine. The proposed method in this study will offer combinations of factors for the specific production requirements and support optimal decision-making in the real-world field.

• Nuclear Engineering and Technology
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• v.26 no.3
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• pp.337-344
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• 1994

Enthalpy rise hot channel factor($F_{\Delta{H}}$$^{N}$) is one of the most limiting constraints in determining the fuel loading pattern(LP) for PWR's. In order to enhance the LP design flexibility without any changes of not only basic fuel specifications but also Technical Specifications and Operation Procedures, we apply the enrichment zoning concept to Westinghouse designed PWR's to flatten the rod power distributions within the fuel assembly and thus to reduce $F_{\Delta{H}}$$^{N}$. Enrichment zoning is described that each assembly consists of two different enrichment fuels ; the lower enriched fuels are located in positions which are expected to have the higher rod power and vice versa for the higher enriched fuels. As a result of unit assembly calculations to flatten the rod power distribution within the assembly, the appropriate enrichment difference is found to be 0.3~0.4w/o. Through core depletion calculations for the 18-month cycle of Kori Unit 4, the $F_{\Delta{H}}$$^{N}$ behavior in core with the enrichment zoning concept is investigated. A comparison with the reference case without the enrichment zoning results in a reduction in $F_{\Delta{H}}$$^{N}$ of approximately 1.5%.TEX>H/$^{N}$ of approximately 1.5%.

• Journal of the Korean Geotechnical Society
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• v.22 no.11
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• pp.123-131
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• 2006

Liquefaction-induced lateral spreading has been the most extensive damage to pile foundations during earthquakes. Several cases of pile failures were reported despite the fact that a large margin of safety factor was employed in their design. In this study, 1-g shaking table tests were performed in order to analyze the failure behavior of piles embedded in liquefied soil deposits by buckling instability. As a result, it can be concluded that the pile subjected to excessive axial loads $(near\;P_{cr})$ can fail easily by buckling instability during liquefaction. When lateral spreading took place in sloping grounds, it was found that lateral loading due to lateral spreading increased lateral deflection of pile and reduced the buckling load. In addition, from the buckling shape of pile, difference between Euler's buckling and pile buckling vat observed. In the case of pile buckling, hinge formed at the middle point of the pile, not at the bottom. And in sloping grounds, location of hinge formation got lower compared with level ground because of the soil movements.

• Journal of the Korean Geotechnical Society
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• v.26 no.3
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• pp.13-23
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• 2010

In this study, centrifuge model tests with 50 g gravitational condition were performed to evaluate the bearing capacity of very soft ground, improved by spreading geotextile and sand on the surface of ground, for the heavy machinery to be able to access. For undrained shear strength of ground model, prepared with the clay sampled from the field, being in the range of 3.1~11.7 kPa, bearing capacity tests were performed with the model footing and the loading system built to simulate the heavy machinery on the ground model treated with geotextile and sand. Test results were compared with theoretically and numerically evaluated ones. Test results about load-settlement curves showed that the bearing capacity increases with the increase of the undrained shear strength of ground. Punching shear or local shear failure was also observed. For a relatively low undrained shear strength of ground, settlement behavior is found to be crucial to evaluating the trafficability of machinery whereas bearing capacity becomes a dominant factor with the increase of undrained shear strength of ground. The method for assessing the bearing capacity of the ground related to trafficability of machinery is presented by acquiring the regression relationship between the contact pressure of machinery and settlements using load-settlement curves with the change of the undrained shear strength. Furthermore, results of numerical analyses about load-settlement relation are in relatively good agreement with those of centrifuge model test.

• Journal of the Korean Geotechnical Society
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• v.24 no.8
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• pp.125-135
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• 2008

Rigid-soft particle mixtures, which consist of sand and rubber, are investigated for the understanding of the stress-deformation and elastic moduli. Specimens are prepared with various size ratio sr between sand and rubber particles, and different volumetric sand fraction sf. Small strain shear waves are measured under $K_o$-loading condition incorporated with the stress-deformation test by using oedometer cell with bender elements. The stress-deformation and small strain shear wave characteristics of rigid-soft particle mixtures show the transition from a rigid particle behavior regime to a soft particle behavior regime under fixed size ratio. A sudden rise of $\Lambda$ factor and the maximum value of the $\zeta$ exponent in $G_{max}=\;{\Lambda}({\sigma}'_{o}/kPa)^{\zeta}$ are observed at $sf\;{\approx}\;0.4{\sim}0.6$ regardless of the size ratio sf. Transition mixture shows high sensitivity to confining stress. The volume fraction for the minimum porosity may depend on the applied stress level in the rigid-soft particle mixtures because the soft rubber particles easily distort under load. In this experimental study, the size ratio and volumetric sand fraction are the important factors which determine the behavior of rigid and soft particle mixtures.