• Title/Summary/Keyword: facilitation of response

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가족친화적 지역사회 특성과 초등학령기 자녀를 둔 취업모의 삶의 만족도 : 일-가족 갈등 및 촉진의 매개효과 (Family-Friendly Community Characteristics and Life Satisfaction of Working Mothers with Elementary School-Age Children: Mediation Effects of Work-Family Conflict and Facilitation)

  • 박인숙
    • 가족자원경영과 정책
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    • 제27권2호
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    • pp.1-17
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    • 2023
  • 본 연구는 가족친화적 지역사회 특성이 초등학령기 자녀를 둔 취업모의 삶의 만족도에 어떠한 관련이 있는지를 살펴보고 그 관계가 취업모의 일-가족 갈등과 촉진에 의해 매개되는지를 살펴보고자 하였다. 이를 위해, 한국아동패널(Panel Study on Korean Children, PSKC) 11차년 자료(2019) 중 취업모 627명의 응답자료를 사용하였고, PROCESS를 사용하여 다중매개효과 분석을 실시하였다. 주요 연구 결과를 요약하면 다음과 같다. 첫째, 이웃의 지지수준이 높을수록 일-가족 촉진이 유의하게 높으며 이는 삶의 만족도를 유의하게 높이는 것으로 나타났다. 둘째, 양육환경 적절성과 지역사회 서비스인프라 이용만족도는 일-가족 촉진을 높이고 갈등을 낮추는 것을 통해 삶의 만족도와 유의한 관련성을 보이는 간접효과를 확인하였다. 특히, 양육환경 적절성은 일-가족 갈등 및 촉진에 의한 간접효과 외에도 삶의 만족도에 직접적으로 관련된 변인으로 나타났다. 반면, 지역사회 서비스인프라 접근 편리성은 일-가족 촉진을 낮춰 삶의 만족도를 낮추는 것으로 나타나, 이와 관련한 후속연구가 필요함을 확인하였다. 이상의 연구결과를 통해, 지역사회의 가족친화적 특성이 취업모의 일-가족 상호접점에 유의하게 관련된 요인임을 확인하고, 지역사회차원에서 이러한 특성을 향상시키고자 하는 노력을 지속적으로 확대해야 할 경험적 근거를 제공했다는 점에서 연구의 의의가 있다.

근육에 대한 역학적 스트레스의 영향 (Review of Effect of the Mechanical Stress on Muscle)

  • 강종호;김진상
    • PNF and Movement
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    • 제6권2호
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    • pp.51-57
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    • 2008
  • Purpose : Mechanical stress activates signaling cascades and leading to a specific response of a network of signaling pathways. The purpose of this study is to review the effect of mechanical stress-induced adaptation in skeletal muscle involves a biological mechanisms. Methods : This is literature study with Pubmed, Medline and books. Results : Skeletal muscle tissue demonstrates a malleability and may adjust its metabilic response, vascularization and neuromuscular characteristic makeup in response to alteration in functional demands. The adaptation in skeletal muscle involoves a multitude of signalling mechanisms related with insuline-like growth factor, vascular endothelial growth factor, neurotrophins. Conclusions : The identification of the basic relationships underlying the malleability of skeletal muscle tissue is likely to be of relevance for our understanding with PNF technique.

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골격근의 활동 의존적 가소성 (Activity-dependent plasticity in skeletal muscle)

  • 김식현
    • PNF and Movement
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    • 제6권1호
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    • pp.41-51
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    • 2008
  • Purpose : This paper reviews evidence supporting adaptive plasticity in skeletal muscle fibers induced by various exercise training and neuromuscular activity. Result : Skeletal muscle fiber demonstrates a remarkable adaptability and can adjust its physiologic and contractile makeup in response to alterations in functional demands. This adaptive plasticity results from the ability of muscle fibers to adjust their molecular, functional, and contractile properties in response to altered physiological demands, such as changes in exercise patterns and mechanical loading. The process of activity-dependent plasticity in skeletal muscle involves a multitude of signalling mechanisms initiating replication of specific genetic sequences, enabling subsequent translation of the genetic message and ultimately generating a series of myosin heavy chain isoform. Conclusions : Knowledge of the mechanisms and interaction of activity-dependent adaptive pathways in skeletal muscle is important for our understanding of the synthesis of muscle myosin protein, maintenance of metabolic and functional capacity with physical activity, and therapeutic intervention for functional improvement.

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Identification and Expression Analysis of Genes Induced in Response to Tomato chlorosis virus Infection in Tomato

  • Sahin-Cevik, Mehtap;Sivri, Emine Dogus;Cevik, Bayram
    • The Plant Pathology Journal
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    • 제35권3호
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    • pp.257-273
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    • 2019
  • Tomato (Solanum lycopersicum) is one of the most widely grown and economically important vegetable crops in the world. Tomato chlorosis virus (ToCV) is one of the recently emerged viruses of tomato distributed worldwide. ToCV-tomato interaction was investigated at the molecular level for determining changes in the expression of tomato genes in response to ToCV infection in this study. A cDNA library enriched with genes induced in response to ToCV infection were constructed and 240 cDNAs were sequenced from this library. The macroarray analysis of 108 cDNAs revealed that the expression of 92 non-redundant tomato genes was induced by 1.5-fold or greater in response to ToCV infection. The majority of ToCV-induced genes identified in this study were associated with a variety of cellular functions including transcription, defense and defense signaling, metabolism, energy, transport facilitation, protein synthesis and fate and cellular biogenesis. Twenty ToCV-induced genes from different functional groups were selected and induction of 19 of these genes in response to ToCV infection was validated by RT-qPCR assay. Finally, the expression of 6 selected genes was analyzed in different stages of ToCV infection from 0 to 45 dpi. While the expression of three of these genes was only induced by ToCV infection, others were induced both by ToCV infection and wounding. The result showed that ToCV induced the basic defense response and activated the defense signaling in tomato plants at different stages of the infection. Functions of these defense related genes and their potential roles in disease development and resistance to ToCV are also discussed.

학령전기 아동 어머니의 양육태도 (Preschool Children Mother's Child Rearing Attitude Using Korean Parent as a Teacher Test)

  • 김신정;김계숙;김영희
    • 부모자녀건강학회지
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    • 제10권1호
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    • pp.3-12
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    • 2007
  • Purpose: The purpose of this study was to test a KPAAT(Korean Parent As a Teacher Test) and provide a basic data to develop parent education program. Methods: This is a secondary analysis study using 103 preschool mothers who were chosen from 2 kindergarten and child care center located at Kyounki-Do. Results: 1) Subjects' child-rearing attitude was above average at the point of $2.86({\pm}\;.20)$. 2) 16 sub-dimension(response to question, permissive attitude of play, control, control of play, expectation about child, understanding about learning, support of learning, encouragement of thinking, provision of imaginary play opportunities, support of play, encouragement of accomplishment motivation, propriety of child-rearing, affectional support, fixed idea, confidence about education, limitation) and 6 factors(response to question, permission of play, control & limitation, evaluation & support about child, encouragement of academic accomplishment, facilitation of the development of creativity) were above 2.50 except ($2.24{\pm}\;.29$) sub-dimension. 3) There was no significant difference statistically according to subjects' general characteristics. Conclusion: From this study, KPAAT can be utilized later childhood period. And nurses need to help mothers to have sound child rearing attitude.

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Release of the Pro-inflammatory Cytokines and Facilitation of Immune Response in LPS-induced Activation of Macrophage by Crude Cordycepin Containing Adenosine(CCCA) from Cordyceps militaris

  • Han, Shin-Ha;Lee, Seung-Jeong;Song, Young-Cheon;Lim, Hee-Jung;Lee, Chong-Kil;Kwon, Oh-Seung;Ha, Nam-Joo;Kim, Kyung-Jae
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.139.2-139.2
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    • 2003
  • The in vitro effects of extracted fractions of C. militaris on the secretion of cytokines in murine macrophage cell line, RAW 264.7 were studied. F1 (crude cordycepin containing adenosine), F2 (ethanol precipitation), F3 (ethanol soluble supernatant) and F4 (fraction of through SK-1B) significantly stimulated the production of cytokine and nitric oxide (NO) on murine macrophage cell line RAW264.7. We examined how the ethanol extract of C. militaris regulates production of interleukine 1-beta(IL-1$\beta$), tumor necrosis factor-alpha (TNF-$\alpha$), and NO in vitro. (omitted)

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Treatment of Drug Susceptible Pulmonary Tuberculosis

  • Shin, Hong-Joon;Kwon, Yong-Soo
    • Tuberculosis and Respiratory Diseases
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    • 제78권3호
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    • pp.161-167
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    • 2015
  • Tuberculosis (TB) remains a major global health problem, and the incidence of TB cases has not significantly decreased over the past decade in Korea. The standard short course regimen is highly effective against TB, but requires multiple TB-specific drugs and a long treatment duration. Recent studies using late-generation fluoroquinolones and/or high-dose rifapentine-containing regimens to shorten the duration of TB treatment showed negative results. Extending the treatment duration may be considered in patients with cavitation on the initial chest radiograph and positivity in sputum culture at 2 months of treatment for preventing TB relapse. Current evidence does not support the use of fixed-dose combinations compared to separate drugs for the purpose of improving treatment outcomes. All patients receiving TB treatment should be monitored regularly for response to therapy, facilitation of treatment completion, and management of adverse drug reactions. Mild adverse effects can be managed with symptomatic therapy and changing the timing of the drug administration, but severe adverse effects require a discontinuation of the offending drugs.

철도 추진 시스템을위한 최적의 배터리 셀 식별을 위한 다양한 배터리 셀의 비교 분석 (Comparative analysis of different battery cells to identify optimal one for Railway Propulsion Systems)

  • 마자하르 압바스;조인호;김종훈
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2018년도 추계학술대회
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    • pp.123-124
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    • 2018
  • Fast response, regenerative energy capturing and commercial maturity of battery characterize it as the best complementary source for hybrid Railway propulsion systems (HRPSs). Although all batteries which have been commercialized do exhibit these features, but on the band of comparative performance and optimization facilitation for HRPSs, every battery occupy different level. This paper is intended to identify the determinants of the performance level in order to select the best option among batteries for HRPSs.

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10년 공공임대아파트 커뮤니티 시설의 운영실태와 커뮤니티 프로그램 요구에 따른 운영 방안 (A Field Study on Community Facility Management of 10-Year Public Rental Apartment Housing and Community Program Management Plan in Response to Tenants' Needs)

  • 강순주;김진영;이보배;조이브
    • 한국주거학회논문집
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    • 제24권5호
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    • pp.77-88
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    • 2013
  • This study is to find out how community facilities of 10-year public rental apartments are currently managed and to propose a new community program management plan by analyzing key characteristics and program needs of tenants. Site visits and questionnaire surveys have been conducted at five different complexes producing 469 results that can be summarized as follows; 1) There were significant differences in the use of facilities and vitality of community among five complexes depending on tenants' participation and efforts of management staff. It was advisable to dispatch specialists, such as housing welfare workers, who were dedicated to managing facilities and supporting community programs; 2) There were high demanded for communication facilitation programs and environmental activities. Development of communication contents and distribution of manuals to inform and educate tenants about various environmental programs will be helpful; 3) The number of community facilities in each complex should be reduced those with high demand and the regional community center should be more vitalized with supporting programs and staff.

고유감각과 전정감각 입력이 외상성 뇌손상 쥐의 BDNF 발현에 미치는 영향 (The Effect of Proprioceptive and Vestibular Sensory Input on Expression of BDNF after Traumatic Brain Injury in the Rat)

  • 송주민
    • PNF and Movement
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    • 제4권1호
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    • pp.51-62
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    • 2006
  • Purpose : The purposes of this study were to test the effect of proprioceptive and vestibular sensory input on expression of BDNF after traumatic brain injury in the rat. Subject : The control group was sacrificed at 24 hours after traumatic brain injury. The experimental group I was housed in standard cage for 7 days. The experimental group II was housed in standard cage after intervention to proprioceptive and vestibular sensory(balance training) for 7 days. Method : Traumatic brain injury was induced by weight drop model and after operation they were housed in individual standard cages for 24 hours. After 7th day, rats were sacrificed and cryostat coronal sections were processed individual1y in goat polyclonal anti-BDNF antibody. The morphologic characteristics and the BDNF expression were investigated in injured hemisphere section and contralateral brain section from immunohistochemistry using light microscope. Result : The results of this experiment were as follows: 1. In control group, cell bodies in lateral nucleus of cerebellum, superior vestibular nucleus, purkinje cell layer of cerebellum and pontine nucleus changed morphologically. 2. The expression of BDNF in contralateral hemisphere of group II were revealed. 3. On 7th day after operation, immunohistochemical response of BDNF in lateral nucleus, superior vestibular nucleus, purkinje cell layer and pontine nucleus appeared in group II. Conclusion : The present results revealed that intervention to proprioceptive and vestibular sensory input is enhance expression of BDNF and it is useful in neuronal reorganization improvement after traumatic brain injury.

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