• Proceedings of the KSPS conference
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• 2003.05a
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• pp.93-96
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• 2003

The present study was conducted to investigate the difference of cortical activation in naming the picture in Korean and English. Experimental design was 2(Korean, English) language condition x 4(no distractor, semantic related distractor, semantic unrelated distrator, corresponding distractor) distractor condition. language condition was between subject factor and distractor condition was within subject factor. The result was that Korean naming condition showed less cortical activation than English naming condition. The activation region was reported in each condition.

• Archives of Pharmacal Research
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• v.22 no.3
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• pp.274-278
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• 1999

Expression of the active urease of the enterobacterium, Klebsiella aerogens, requires the presence of the accessory genes (ureD, ureE, ureF, and ureG) in addition to the three structural genes (ureA, ureB, and ureC). These accessory genes are involved in functional assembly of the nickel-metallocenter for the enzyme. Characterization of ureF gene has been hindered, however, since the UreF protein is produced in only minute amount compared to other urease gene products. In order to overexpress the ureF gene, a recombinant pMAL-UreF plasmid was constructed from which the UreF was produced as a fusion with maltose-binding protein. The MBP-UreF fusion protein was purified by using an amylose-affinity column chromatography followed by an anion exchange column chromatography. Polyclonal antibodies raised against the fusion protein were purified and shown to specifically recognize both MBP and UreF peptides. The UreF protein was shown to be unstable when separated from MBP by digestion with factor Xa.

• Journal of Microbiology and Biotechnology
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• v.15 no.4
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• pp.838-843
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• 2005

Brain-derived neurotrophic factor (BDNF) is a small secretory protein and a member of the nerve growth factor (NGF) gene family. We cloned the flounder BDNF gene from a flounder brain cDNA library. The nucleotide sequence of the cloned gene showed an open reading frame (ORF) consisting of 810 bp, corresponding to 269 amino acid residues. The tissue distribution of flounder BDNF was determined by reverse transcription-polymerase chain reaction (RT-PCR) in brain, embryo, and muscle tissues. To express fBDNF using a eukaryotic expression system, we constructed the vector mpCTV-BDNF containing the fBDNF gene and transformed this vector into Chlorella ellipsoidea. Stable integration of introduced DNA was confirmed by PCR analysis of genomic DNA, and mRNA expression in C. ellipsoidae was confirmed by RT-PCR analysis.

• Tuberculosis and Respiratory Diseases
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• v.53 no.6
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• pp.595-611
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• 2002

Akt/PKB protein kinase B, ALI acute lung injury, ARDS acute respiratory distress syndrome, CREB C-AMP response element binding protein, ERK extracelluar signal-related kinase, fMLP fMet-Leu-Phe, G-CSF granulocyte colony-stimulating factor, IL interleukin, ILK integrin-linked kinase, JNK Jun N-terminal kinase, LPS lipopolysaccharide, MAP mitogen-activated protein, MEK MAP/ERK kinase, MIP-2 macrophage inflammatory protein-2, MMP matrix metalloproteinase, MPO myeloperoxidase, NADPH nicotinamide adenine dinucleotide phosphate, NE neutrophil elastase, NF-kB nuclear factor-kappa B, NOS nitric oxide synthase, p38 MAPK p38 mitogen activated protein kinase, PAF platelet activating factor, PAKs P21-activated kinases, PMN polymorphonuclear leukocytes, PI3-K phosphatidylinositol 3-kinase, PyK proline-rich tyrosine kinase, ROS reactive oxygen species, TNF-${\alpha}$ tumor necrosis factor-a.

• 한국전산유체공학회:학술대회논문집
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• 2008.03b
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• pp.121-125
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• 2008

In this study, the characteristics of internal flow and the heat transfer performance of dimpled plate heat exchanger were numerically investigated. For the numerical analysis, conjugate heat transfer method between cold fluid - plate - hot fluid was studied with appropriate boundary conditions. Velocity magnitude, temperature and pressure distribution were obtained from the simulation. Correlations for fanning f-factor and Colburn j-factor were obtained from numerical results and compared to the experimented data.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2000.10a
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• pp.434-439
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• 2000

In this paper, in order to study the geometric factor effect of a circular hole near a crack tip in a semi-infinite plate, the Dimensionless Stress Intensity Factor, $F(=\frac K {\sigma {\sqrt{\pi a}}})$ is analyzed at the crack tip using a two Dimensional Boundary Element Method (BEM) program which is known as superior in Fracture Mechanics. Kelvin's solution was used as a fundamental solution in BEM analysis and displacement extrapolation method was used to determine Stress Intensity Factor.

• Nuclear Engineering and Technology
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• v.49 no.4
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• pp.838-849
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• 2017

This paper proposes penalty factor equations that take into consideration the weld strength over-match given in the classified form similar to the revised equations presented in the Code Case N-779 via cyclic elastic-plastic finite element analysis. It was found that the $K_e$ analysis data reflecting elastic follow-up can be consolidated by normalizing the primary-plus-secondary stress intensity ranges excluding the nonlinear thermal stress intensity component, $S_n$ to over-match degree of yield strength, $M_F$. For the effect of over-match on $K_n{\times}K_{\nu}$, dispersion of the $K_n{\times}K_{\nu}$ analysis data can be sharply reduced by dividing total stress intensity range, excluding local thermal stresses, $S_{p-lt}$ by $M_F$. Finally, the proposed equations were applied to the weld between the safe end and the piping of a pressurizer surge nozzle in pressurized water reactors in order to calculate a cumulative usage factor. The cumulative usage factor was then compared with those derived by the previous $K_e$ factor equations. The result shows that application of the proposed equations can significantly reduce conservatism of fatigue assessment using the previous $K_e$ factor equations.

• The Korean Journal of Mycology
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• v.39 no.3
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• pp.217-222
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• 2011

Job's tears (Coix lacryma-jobi) is native to East Asia, and grains of the plant are used as health food and medicinal material. Head blight symptoms of the plant were frequently observed during disease surveys in Korea from 2006 to 2008. The symptoms were characterized as discoloration of husks, and subsequently inside of mature grains were shriveled or emptied. One hundred fifty nine isolates of Fusarium species were obtained from the disease symptoms of the plant collected from several locations in the country. Out of the isolates, the most frequently isolated Fusarium species were F. graminearum (34%), F. proliferatum (14.5%), F. verticillioides (10.1%), F. equiseti (6.9%), and F. fujikuroi (6.3%). Other Fusarium species isolated were F. subglutinans, F. semitectum, F. poae, and F. sporodochioides. Elongation factor 1 alpha gene sequences of the isolates were used for phylogenetic analysis. Analyses of the sequences revealed that the isolates were confirmed to be identical with each reference species of NCBI GenBank. Pathogenicity tests showed that F. graminearum, F. proliferatum and F. verticillioides were strongly virulent to grains of Job's tears. The present study is the first report of head blight of Job's tears caused by Fusarium species in Korea.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.9 no.1
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• pp.41-55
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• 1999

In order to evaluate the effects of knowledge, attitude and practice on noise-induced hearing loss or hearing threshold level, questionnaire survey was performed and hearing thresholds of 1 kHz and 4 kHz were measured on 1,040 subjects with workers exposed to noise, safety and health officers. industrial hygienists, analysts rind office workers. The results were as follows ; 1. The following 6 factors were obtained by factor analysis and factor rotation of 30 questionnaire of knowledge, attitude and practice about noise; knowledge of noise (F1), concern of hearing protective devices (F2), concern of noise induced hearing loss (F3), concern of noise level and hearing impairment (F4), concern of noise in workplace (F5) and recognition of noised-induced hearing loss (F6). 56.1% of variance was explained by 6 factors. 2. Significant variables influencing knowledge, attitude and practice about noise were education level and age in F1, personal protective devices (PPE) and education level in F2, age and education level in F3, education level, age and sex in F4, PPE, education level, age and work duration in F5, and work duration and PPE in F6. 3. Hearing thresholds of 4 kHz were significantly higher in workers exposed to noise than that of in the other subjects and tended to be higher in industrial hygienists, safety and health officers and analysts than that of the office workers. 4. Significant variables influencing hearing thresholds of 1 kHz were age, education level, F5 and F6 in workers exposed to noise, and F1 in industrial hygienists. 5. Significant variables influencing hearing thresholds of 4 kHz were age, F6, sex, work duration, F1, F5, F2 and F3 in workers exposed to noise, F1 and age in safety and health officers, and F6, sex and F4 in industrial hygienists. With the above results, it suggested that workers exposed to noise be needed the education of knowledge, attitude and practice about noise in hearing conservation program for the prevention of noise induced hearing loss. Also, it suggested that health managers in workplace be needed countermeasures to prevent hearing loss although they are intermittently exposed to noise.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.5
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• pp.3051-3059
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• 2015

In this study, the effect of corrugation angle on thermal performance of corrugated plate is numerically investigated with an aim to develop humidifying element. Numerical analysis was conducted for a range of corrugation angle (from $0^{\circ}/0^{\circ}$ to $60^{\circ}/60^{\circ}$ for equal angle and from $15^{\circ}/0^{\circ}$ to $15^{\circ}/60^{\circ}$ for unequal angle). Results revealed that both j and f factor increased as corrugation angle increased. Especially, f factor increased significantly at high corrugation angles. j and f factors of unequal angle plates and those of equal angle (obtained by averaging unequal angles) plates were approximately the same. The largest $j/f^{1/3}$, which implies the largest heat transfer rate per consumed power, was obtained at $15^{\circ}/15^{\circ}$. Existing correlations under- or over-predicted the present numerical results.