• The korean journal of orthodontics
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• v.52 no.2
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• pp.102-111
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• 2022

Objective: To develop and explore the usefulness of an artificial intelligence system for the prediction of the need for dental extractions during orthodontic treatments based on gender, model variables, and cephalometric records. Methods: The gender, model variables, and radiographic records of 214 patients were obtained from an anonymized data bank containing 314 cases treated by two experienced orthodontists. The data were processed using an automated machine learning software (Auto-WEKA) and used to predict the need for extractions. Results: By generating and comparing several prediction models, an accuracy of 93.9% was achieved for determining whether extraction is required or not based on the model and radiographic data. When only model variables were used, an accuracy of 87.4% was attained, whereas a 72.7% accuracy was achieved if only cephalometric information was used. Conclusions: The use of an automated machine learning system allows the generation of orthodontic extraction prediction models. The accuracy of the optimal extraction prediction models increases with the combination of model and cephalometric data for the analytical process.

• Journal of Ginseng Research
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• v.10 no.1
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• pp.80-93
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• 1986

The tail portion of dried 6-year old white ginseng was extracted and sugars and nitrogen compounds were also evaluated for chemical properties depending on varying conditions of extractions. The factors studied were extraction temperature in the range of 70-$100^{\circ}C$, ethanol concentration of 0-90% and the times of extractions which was taken 8 hours per each extraction in water at $80^{\circ}C$. For the effect of ethanol concentration in the extraction solvent, it was found that the amounts of free, reducing and total sugars and starch recovered in extract were almost linearly decreased along with the increase of concentration and the nonprotein nitrogen accounted over 84% of total nitrogen in extract. As ethanol concentration became increased, extractions of total nitrogen and water souluble nonprotein nitrogen were decreased especially in 90% ethanol. For the extraction temperature, all the sugar fractions with water and 70% ethanol except free sugar have tended to increase along with the temperature raised from 70 to $100^{\circ}C$ and it was found there is little changes of nitrogen compounds in the temperature range except a rapidly increase in water soulble protein at $100^{\circ}C$. For the times of extractions, showed that most of extractable compounds were extracted in 3 times of extractions with water at $80^{\circ}C$. It was shown that more than 95f) of sugars and 80% of nitrogen compounds were yielded with water extraction. Accordingly it was efficient to extract with water or 70% ethanol in 3 times in terms of !actor and energy consumption.

• The korean journal of orthodontics
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• v.27 no.6 s.65
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• pp.905-916
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• 1997

The purpose of this investigation were to evaluate facial vortical changes occurring in patients treated orthodontically with first premolar, second remolar and second molar extractions : to compare these changes with those occurring in patients treated orthodontically without extractions : and finally, to evaluate the effects of extractions in facial vortical changes. Cephalometric records of 50 male & female nonextraction patients and 88 male & female extraction patients were obtained from the department of orthodontics at Chosun University, College of Dentistry. The second molar fully erupted pPatients to have little variation according to growth were chosen as the sample for this investigation. For comparisons, the samples of 88 male & female extraction patients were subdivided into 42 first premolar extraction, 24 second premolar extraction, and 22 second molar extraction patients. Fourteen cephalometric measurements were selected to examine whether orthodontic extraction treatment led to vertical changes or not. The pretreatment and posttreatment lateral cephalographs were taken on the same radiographic unit. $SPSS/PC^+$ statistical program was used to compare and to analyze the changes between 'before & after' orthodontic treatment. The results of this study were as follows. 1. There were no statistical significances in any cephalometric measurements between 'before & after' orthodontic treatment regardless of orthodontic extractions for each group. 2. On average, the upper 6 to palatal Plane and the lower 6 to mandibular plane after orthodontic treatment were increased in all group. This means most of orthodontic mechanics are extrusive in nature. Especially, in orthodontic extraction. cases, it may be caused by orthodontic mechanics for space closure and alignments. 3. On average, in the second molar extraction group, the facial vertical dimension was increased after orthodontic treatment. It nay be induced as a result of moving the molars distally to gain enough space to correct the molar relationship and to simultaneously improve the deep bite. 4. There was no statistical significance between orthodontic extractions and facial vertical changes. This means that orthodontic extractions have no influence on facial vortical changes. 5. The cephalometric measurements with statistical significance in ficial vertical changes for each group were PP-MP, Op-MP, $\underline{1}$ to PP and $\overline{1}$ to MP.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 1998.11a
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• pp.183-188
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• 1998

The efficiency of removing cadmium, copper, and lead from a contaminated soil of abandoned metal mine was studied in a laboratory investigation where citric acid were used to extract the metal from the soil. The contamination level of Pb, Cu in the soil A were 875.5, 667.5mg/kg respectively. The mobility and bioavailability of the metals in soil were also estimated by Sequential Chemical Extractions. Citric acid were examined for its potential extractive capabilities. Concentrations of the acid examined in this study ranged from 0.025 to 0.15M. The pH of the suspensions and S/S ratio in which the extractions were performed ranged from 2.4 to 8.1, and from 2.1:1 to 20:1. Results showed that the removal of contaminant using citric acid was pH and S/S raton dependent.

• Journal of the Korean Institute of Intelligent Systems
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• v.23 no.5
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• pp.400-405
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• 2013

The purpose of this study is to develop a composite platform for knowledge extractions, visualizations, and inference. Generally, the big data sets were frequently used in the healthcare and medical area. To help the knowledge managers/users working in the field, this study is focused on knowledge management (KM) based on Data Mining (DM), Knowledge Distribution Map (KDM), Decision Tree (DT), RDBMS, and SQL-inference. The proposed mechanism is composed of five key processes. Firstly, in Knowledge Parsing, it extracts logical rules from a big data set by using DM technology. Then it transforms the rules into RDB tables. Secondly, through Knowledge Maintenance, it refines and manages the knowledge to be ready for the computing of knowledge distributions. Thirdly, in Knowledge Distribution process, we can see the knowledge distributions by using the DT mechanism.Fourthly, in Knowledge Hierarchy, the platform shows the hierarchy of the knowledge. Finally, in Inference, it deduce the conclusions by using the given facts and data.This approach presents the advantages of diversity in knowledge representations and inference to improve the quality of computer-based medical diagnosis.

• Journal of Ginseng Research
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• v.4 no.1
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• pp.88-95
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• 1980

Red ginseng was extracted with water and analyzed for yield, saponin, pectin and other chemical composition. It was found that: (1) The total solid content in extract after 6 times of extraction was 46.8%,: including 13.6% of centrifugal residue; (2) 83.7% of total extractable solids and 86% total saponin was extracted after the initial three runs of extraction. (3) No significant changes were observed in HPLC pattern of extracted saponins over a range of extractions; (4) The ratio of centrifugal residue to total solids increased as the number of extractions increased; (5) The ratios of fat, protein, reducing sugar and pectin contents decreased with repeating extraction while those of crude fiber, total sugar and 35% alcohol insoluble residue increased when they were compared with total solids.

• Analytical Science and Technology
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• v.17 no.4
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• pp.295-301
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• 2004

In this study, static and dynamic solvent extractions are compared for more efficient extraction of polychlorinated dibenzofurans (PCDFs) from fly ash. Static solvent extraction rather than dynamic extraction showed a higher recovery of PCDFs, which was adsorbed strongly with fly ash. The effects of parameters, such as temperature, toluene-isopropyl alcohol mixture, static and dynamic time flow rate, and solvent volume on the extraction were investigated and the variations in average recoveries of PCDFs were explained. In both extractions, temperature was an effective parameter because the higher temperature gave the higher recoveries. In dynamic solvent extraction, dynamic time was more effective than flow rate and solvent volume for the extraction of PCDFs from fly ash. Multi-layer column chromatography on neutral and acidic silica gel with n-hexane was used for cleaning up the extracts. The quantification of the PCDFs extracted was performed using HPLC-UV.

• Journal of Acupuncture Research
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• v.31 no.4
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• pp.45-55
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• 2014

Objectives : The main aim of this study was to assess the comparative efficiency of two preparation types of Hwangryunhaedok decoction(HRHD-D) using distilled and mixed extraction by measuring the index components and indicators of antioxidant and anti-inflammatory effects. Methods : The antioxidant activity was assessed by comparing distilled and mixed extractions of HRHD-D using an ELISA reader. The anti-inflammatory effect was determined by measuring NO amounts in RAW 264.7 cells. The contents were analyzed with high performance liquid chromatography-diode array detector(HPLC-DAD). Results : The electron donating ability of mixed and distilled extractions obtained with 500 ppm DPPH(1,1-diphenyl-2-picrylhydrazyl assay) solution were 57.8 % and 4.2 %, respectively. The total phenolic content of mixed extraction was 6.9 times that of distilled extraction and total flavonoid content was 51.5 times higher. The anti-inflammatory effect was assessed by NO measurement, and was found to increase significantly dependent on concentration in all mixed extract concentrations(25, 50, 100, 200, $400{\mu}g/mL$), but the difference in distilled extraction by concentration was only significant at 200 and $400{\mu}g/mL$. The HPLC analysis results of mixed extract of HRHD-D showed detection of all four main active constituents of HRHD-D. However, they were not detected in the distilled extract of HRHD-D. Conclusions : Mixed extraction with distillation added to decoction of HRHD-D showed better efficacy in antioxidant and anti-inflammatory effects, and ingredient quantities compared to distilled extraction. Further stability and clinical efficacy studies for standardization of mixed extractions are required.

• Journal of Pharmacopuncture
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• v.14 no.1
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• pp.79-86
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• 2011

Objective : This study was performed to compare anti-inflammation, anti-oxidation and anti-bacterial effects of Cuscutae Semen(CS) extracted with two kinds of solvents, ethanol and distilled water. Methods : Two kinds of CS extractions were prepared 20, 50, 100 ${\mu}l/mg$. The cytotoxicity was measured by MTT assay in Raw 264.7 cell. The anti-inflammation effect was measured by inhibitory efficacy of NO Production in Raw 264.7 cell. The anti-oxidation effect was measured by DPPH Radical scavenging ability in HaCaT cell. The anti-bacterial effect was measured by inhibition zone diameter on Propionibacterium acnes. Results : 1. Two kinds(100 ${\mu}l/mg$) of CS extraction groups had 50% cytotoxicity in Raw 264.7 cell. 2. All of CS extraction groups were not showed significantly inhibitory effect on NO production. 3. All of CS extracted with ethanol only showed dose-dependently significantly scavenging effect of DPPH radicals. 4. Two kinds of CS extractions did not have a inhibitory effect on Propionibactrium acnes. Conclusion : Two kinds(100 ${\mu}l/mg$) of CS extraction groups have 50% cytotoxicity. Two kinds of CS extractions have not the inhibitory effect on NO production and Propionibactrium acnes. CS groups extracted with ethanol only have a significantly scavenging ability of DPPH radicals. This study suggests that CS extracted with ethanol was effective in anti-oxidation.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.47 no.3
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• pp.190-196
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• 2021

Objectives: The risk of bleeding after tooth extraction in thrombocytopenia patients remains unclear. Therefore, the present study aimed to assess the risk of bleeding after tooth extraction in patients with thrombocytopenia. Materials and Methods: The study included 220 patients who had a medical history of thrombocytopenia and underwent tooth extraction (330 teeth). The patients were divided into those who had thrombocytopenia (platelet count <150k) immediately before the tooth extraction, and those who had platelet counts that were between 150k and 250k before the extraction. Bleeding complications were recorded and compared between the patient groups. Results: Of the 220 patients, 130 underwent tooth extractions while having thrombocytopenia (platelet count <150k), and 90 had platelet counts that were between 150k and 250k before tooth extractions. Bleeding complications occurred in 11 patients (5.0%) of the 220 patients. Among those 11 patients with bleeding complications, 10 patients (7.7%) had thrombocytopenia (platelet count <150k) of the 130 patients, and 1 patient (1.1%) had a normal platelet count of the 90 patients. There was a significant difference between the patient groups regarding bleeding after extractions (P<0.001). No significant difference in the incidence of post-extraction bleeding was found between the subgroups by platelet count within the thrombocytopenia group. Conclusion: Thrombocytopenia (platelet count <150k) increases the risk of post-tooth extraction bleeding. Therefore, bleeding control under the proper evaluation of hemostasis and performing delicate tooth extraction procedures using hemostatic plugs is necessary during the tooth extraction of patients with thrombocytopenia.