• 제목/요약/키워드: exposure criteria

검색결과 308건 처리시간 0.024초

Association of added sugar intake with all-cause and cardiovascular disease mortality: a systematic review of cohort studies

  • Song, SuJin;Shim, Jae Eun;Song, YoonJu
    • Nutrition Research and Practice
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    • 제16권sup1호
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    • pp.21-36
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    • 2022
  • BACKGROUND/OBJECTIVES: The long-term health impacts of dietary sugar have begun to be reported. The committee on the 2020 Dietary Reference Intakes for Koreans for sugar intended to update the scientific evidence on the association of added sugar intake with health outcomes, including mortality. This study evaluated the evidence on the association of dietary sugar with the all-cause and cardiovascular disease mortality from cohort studies. SUBJECTS/METHODS: The PubMed and ScienceDirect databases were searched until July 2021. The search terms were based on multiple combinations of keywords, such as added sugar, beverage, and mortality, included in the title or abstract. Two authors independently assessed the eligibility criteria of study selection and extracted the information from each selected article for this systematic review. RESULTS: The literature search identified 276 articles. Seventeen cohort studies met the inclusion criteria and were included in this systematic review. This study extracted information on the cohort and participants, dietary assessment methods, exposure and its comparison groups, health outcomes, and risk measures. Five articles reported added sugar intake, and 15 articles reported the food sources of the added sugar in the association with mortality. Increased mortality was observed in higher added sugar intake and a lower intake of less than 5% of energy, while higher discrepancies between gender, age groups, and countries were noted. In addition, nutritious sugary foods and beverages did not increase mortality. CONCLUSIONS: A 'U' or 'J' shaped relationship between the added sugar intake and mortality was estimated. The observed discrepancy indicated the need for more evidence to establish the dose-response relationship for Koreans.

Review of Shielding Evaluation Methodology for Facilities Using kV Energy Radiation Generating Devices Based on the NCRP-49 Report

  • Na Hye Kwon;Hye Sung Park;Taehwan Kim;Sang Rok Kim;Kum Bae Kim;Jin Sung Kim;Sang Hyoun Choi;Dong Wook Kim
    • 한국의학물리학회지:의학물리
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    • 제33권4호
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    • pp.53-62
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    • 2022
  • In this study, we have investigated the shielding evaluation methodology for facilities using kV energy generators. We have collected and analysis of safety evaluation criteria and methodology for overseas facilities using radiation generators. And we investigated the current status of shielding evaluation of domestic industrial radiation generators. According to the statistical data from the Radiation Safety Information System, as of 2022, a total of 7,679 organizations are using radiation generating devices. Among them, 6,299 facilities use these devices for industrial purposes, which accounts for a considerable portion of radiation. The organizations that use these devices evaluate whether the exposure dose for workers and frequent visitors is suitable as per the limit regulated by the Nuclear Safety Act. Moreover, during this process, the safety shields are evaluated at the facilities that use the radiation generating devices. However, the facilities that use radiating devices having energy less than or equal to 6 MV for industrial purposes are still mostly evaluated and analyzed according to the National Council on Radiation Protection and Measurements 49 (NCRP 49) report published in 1976. We have investigated the technical standards of safety management, including the maximum permissible dose and parameters assessment criteria for facilities using radiation generating devices, based on the NCRP 49 and the American National Standards Institute/Health Physics Society N.43.3 reports, which are the representative reports related to radiation shielding management cases overseas.

과소/과잉노동과 근로환경 (Under and Over Employment and Working Conditions)

  • 이경용;송세욱;김영선
    • 한국산업보건학회지
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    • 제24권4호
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    • pp.536-546
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    • 2014
  • Objectives: The major objective of this paper is compare the exposure work hours and experieence of ill health symptoms among under and over employment and matched group. Workers with over employment have more exposed to hazards than that with under employment because that workers with over employment work more than those with ender employment. Methods: This study as heuristics one used the third Korean Working Conditions Survey done by Occupational Safety and Health Research Institute in 2011. The sample size is 50,023 economic active persons. Over and under employment were measured by matching method of preferred and actual work hours. The exposed work hours to hazards were measured according to 13 hazardous factors and the experience of ill health symptoms were scaled by the number of experienced 14 ill health symptoms. To compare the exposure and the symptoms experience were compared by mean difference test with F test. Results: The proportion of over employment in male employees is 32.1% and that in female employees is 29.3% and under employment rate is 11.2% in mae and 13.9% in female employees. There is significant difference of the rate of over and under emplyment among age groups, industrial sectors, occupational groups and the state of employment. The difference of the exposed work hours to hazards among under, over and matched group were statistically significant in all hazards by gender. The exposed work hours to hazards in over employment were more than those in under employment. The number of experienced symptoms in over employment is statistically significantly more than that in under employment. Conclusions: Workers with over employment may be vulnerable group in the criteria of hazard exposure and health status. The results have some implications and limitations because that this study is heuristic one. The mismatch of preferred and actual working hours may be unfavorable work condition that has impact on safety and health of workers. The impact mechanism may be investigated as future study, Because that this study used cross sectional survey data, some causal relationships cannot be evaluated.

Quantitative Microbial Risk Assessment for Clostridium perfringens in Natural and Processed Cheeses

  • Lee, Heeyoung;Lee, Soomin;Kim, Sejeong;Lee, Jeeyeon;Ha, Jimyeong;Yoon, Yohan
    • Asian-Australasian Journal of Animal Sciences
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    • 제29권8호
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    • pp.1188-1196
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    • 2016
  • This study evaluated the risk of Clostridium perfringens (C. perfringens) foodborne illness from natural and processed cheeses. Microbial risk assessment in this study was conducted according to four steps: hazard identification, hazard characterization, exposure assessment, and risk characterization. The hazard identification of C. perfringens on cheese was identified through literature, and dose response models were utilized for hazard characterization of the pathogen. For exposure assessment, the prevalence of C. perfringens, storage temperatures, storage time, and annual amounts of cheese consumption were surveyed. Eventually, a simulation model was developed using the collected data and the simulation result was used to estimate the probability of C. perfringens foodborne illness by cheese consumption with @RISK. C. perfringens was determined to be low risk on cheese based on hazard identification, and the exponential model ($r=1.82{\times}10^{-11}$) was deemed appropriate for hazard characterization. Annual amounts of natural and processed cheese consumption were $12.40{\pm}19.43g$ and $19.46{\pm}14.39g$, respectively. Since the contamination levels of C. perfringens on natural (0.30 Log CFU/g) and processed cheeses (0.45 Log CFU/g) were below the detection limit, the initial contamination levels of natural and processed cheeses were estimated by beta distribution (${\alpha}1=1$, ${\alpha}2=91$; ${\alpha}1=1$, ${\alpha}2=309$)${\times}$uniform distribution (a = 0, b = 2; a = 0, b = 2.8) to be -2.35 and -2.73 Log CFU/g, respectively. Moreover, no growth of C. perfringens was observed for exposure assessment to simulated conditions of distribution and storage. These data were used for risk characterization by a simulation model, and the mean values of the probability of C. perfringens foodborne illness by cheese consumption per person per day for natural and processed cheeses were $9.57{\times}10^{-14}$ and $3.58{\times}10^{-14}$, respectively. These results indicate that probability of C. perfringens foodborne illness by consumption cheese is low, and it can be used to establish microbial criteria for C. perfringens on natural and processed cheeses.

동결융해 및 제설제에 노출된 고속도로 소구조물 콘크리트의 내구성 개선 연구 (A Study on the Durability Improvement of Highway-Subsidiary Concrete Structure Exposed to Deicing Salt and Freeze-Thaw)

  • 이병덕;최윤석;김영근;최재석;김일순
    • 한국구조물진단유지관리공학회 논문집
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    • 제20권4호
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    • pp.128-135
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    • 2016
  • 현재 고속도로의 콘크리트 구조물에서 대부분 지속되고 있는 가장 큰 문제는 동결 융해와 제설염에 의해 발생하는 콘크리트 열화이고, 이는 완전하게 해결되지 않은 쟁점사항이다. 특히, 동결융해만이 작용할 때와는 달리 동결 융해와 제설염의 복합열화 환경에서 콘크리트의 내구성능은 급격하게 저하되고 공용수명이 단축된다. 본 연구에서는 지역별 고속도로 구간의 노출환경등급을 수립하고 콘크리트 손상정도와 염화물량을 조사하였다. 또한 기계타설 소구조물 콘크리트의 내구성 향상을 위해 배합조건을 개선한 콘크리트의 염화물 이온 투과성, 박리저항성, 동결 융해 저항성 시험을 수행하였다. 연구결과에 따르면, 특수환경에 노출된 콘크리트 표면의 손상범위가 광범위하게 나타났으며 내부 염화물량 또한 높게 나타났다. 한편, 물-결합재(W/B) 비 및 단위수량을 적게 하고, 플라이애시를 혼합하여 내구성을 개선한 콘크리트는 기존의 배합비 보다 내구성이 크게 향상되었다. 또한 도출한 최적 배합비는 콘크리트 관련 시방서에서 제시하고 있는 강도 및 공기량, 물-결합재 비 등의 기준에 부합하였고, 내구성 기준에 만족할 뿐 아니라 공용수명이 크게 향상될 것으로 판단된다.

아급성흡입독성시험을 이용한 3-Methylpentane의 GHS 분류·표시 (A Study on GHS Classification of 3-Methylpentane by Subacute Inhalation Toxicity)

  • 정용현;한정희;신서호
    • 한국가스학회지
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    • 제21권1호
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    • pp.6-17
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    • 2017
  • 본 연구는 3-methylpentane에 대한 흡입유해성을 평가하여 국제연합에서 정하는 화학물질의 분류 및 표지에 관한 세계조화시스템(Globally harmonized system, GHS)지침 및 고용노동부고시 제2013-37호에 따른 3-methylpentane의 화학물질 분류 표시 자료를 생산하기 위하여 OECD 화학물질 시험가이드라인 아급성흡입독성시험 TG 412(Subacute inhalation toxicity) 시험법에 따라 수행하였다. 본 연구를 위하여 6주령의 랫드(Rat)를 도입하여 1주간 순화시킨 후 암수 각각 대조군 5마리, 저농도군(284 ppm) 5마리, 중농도군(1,135 ppm) 5마리, 고농도군(4,540 ppm) 5마리 등으로 군을 구성하여 일일 6시간, 주 5일, 4주 동안 시험물질을 랫드에 전신으로 노출시켰다. 시험물질 노출을 종료하고 2주 후 시험동물을 희생하여 시험물질에 의한 시험동물의 영향을 평가하였다. 사료섭취량 변화, 체중 변화, 임상관찰, 혈액검사, 부검 소견, 장기무게 측정, 조직병리검사 등 모든 시험결과에서 시험물질에 의한 영향은 나타나지 않아 3-methylpentane의 무유해영향농도는 암수 모두 4,540 ppm이상으로 판단되어 세계조화시스템(GHS) 지침 및 고용노동부고시 제2013-37호(화학물질의 분류 표시 및 물질안전보건에 관한 기준)의 특정표적장기독성(반복노출) 구분 표시 물질에 해당하지 않은 물질로 판단되었다.

디지털 영상 시스템에서 선량 크리프 최소화를 위한 부가 필터 두께 권고 기준의 재설정에 대한 연구 (The Necessity of Resetting the Filter Criteria for the Minimization of Dose Creep in Digital Imaging Systems)

  • 김교태;김금배;강상식;박지군
    • 한국방사선학회논문지
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    • 제13권5호
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    • pp.757-763
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    • 2019
  • 최근 넓은 동적 범위 특성을 제공하는 평판 디텍터 개발을 바탕으로 의료보건 환경이 디지털화되고 있는 현 시점에서 적절한 필터 두께의 재설정이 요구되고 있으나, 현 임상에서는 기존 아날로그 시스템에서 연구된 정보를 바탕으로 NCRP에서 제안한 권고 기준을 이용하고 있다. 이에 본 연구에서는 디지털방사선 촬영에서 알루미늄 필터를 이용하여 환자선량 최적화와 더불어 선량크리프의 최소화 가능성을 고찰하였다. 연구 결과, 알루미늄 필터의 두께를 증가함에 따라 유사한 선예도를 가지는 의료영상을 획득 시 피폭되는 피부입사선량을 최대 19.3% 저감할 수 있는 것으로 나타났으나, 영상학적 관점에서 중요한 해상력이 1.01 lp/mm의 큰 변화가 분석되었다. 이러한 해상력의 변화는 X선 빔 경화 현상으로 인하여 피사체에서 발생하는 산란선이 증가하기 때문으로 사료되며, 산란 열화 인자를 통하여 산란선량에 의한 영향이 증가하는 것을 정량적으로 검증하였다. 하지만, 최근 개발되어 광범위하게 적용되고 있는 평판 디텍터는 방사선에 대한 민감도가 높고 넓은 동적 범위 특성을 가지므로 필터 두께에 따라 산란선의 비율에 대한 증가분과 대응하여 적정한 해상력을 유지할 수 있을 것으로 사료되며, 더 나아가 피폭선량 저감을 통해 선량크리프를 최소화 할 수 있을 것으로 기대된다.

작업자세와 작업시간을 고려한 농작업의 인간공학적위험성 평가 방법의 제안 (Suggestion of a Method to Assess the Risk Level of Agricultural Works Considering Work Posture and Working Time)

  • 박희석;이윤근;김효철;이경숙
    • 대한인간공학회지
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    • 제36권5호
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    • pp.601-607
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    • 2017
  • Objective: A method to assess the risk level of agricultural works considering work posture and working time was suggested, and the method was applied to the major fruit crops. Background: It is not complete to analyze only work postures when assessing risk level of agricultural works. Method: $3{\times}3$ matrix was employed, in which the severity level was taken from the REBA method and exposure level was taken from the working time, using the criteria of caution zone/hazard zone. Results: Among the 5 major fruit crops(apple, pear, grape, peach, persimmon), the highest level of ergonomic risk was found in the apple and pear, while medium level was found in other 3 crops, mainly because the working time was less in the 3 crops. Conclusion: It was found that when assessing the overall ergonomic risk of agricultural works, work posture and working time should be considered at the same time. Application: The suggested method could be applied to other non-cyclic tasks.

모바일 RFID 서비스 환경에서의 성인 인증 시스템 (Adult Certification System on Mobile RFID Service Environments)

  • 김영수;박남제;홍도원;원동호
    • 한국콘텐츠학회논문지
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    • 제9권1호
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    • pp.131-138
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    • 2009
  • 본 논문은 유비쿼터스 환경의 핵심 기술인 RFID(Radio Frequency IDentification) 기술과 이동통신 기술의 접목을 통해 도래하게 될 모바일 RFID 서비스 환경에서의 성인 인증에 관한 것으로, 기존의 인터 넷에서 행하고 있는 단순한 성인 인증의 단점을 극복하기 위하여, 콘텐츠의 내용에 기반한 등급 분류 체계를 갖추고, 이를 통한 성인 인증 시스템을 제안한 것이다. 우선 기존의 성인 인증 방법에 대하여 설명하고, 청소년들에게 유해 정보가 노출되는 것을 막기 위한 콘텐츠 내용에 기반한 등급 분류 기준에 대하여 알아본다. 그리고, 제안하는 모바일 RFID 성인 인증 데이터의 구성을 살펴본 후, 모바일 RFID 성인 인증 시스템을 제안하고 결론을 맺는다.

두경부 재건에 융용한 두가지 도서형 피판 : 대흉근피판과 외측 승모근피판 (Versatile Two Island Flaps for Head and Neck Reconstruction)

  • 이혜경;신극선;김광문
    • 대한두경부종양학회지
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    • 제7권2호
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    • pp.92-98
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    • 1991
  • Numerous mycoutaneous island flaps or free flaps have been used to reconstruct a defect which resulted from the wide resection of tumor mass in head and neck region. Since the curative resection of tumor usually include muscles and bones as well as skin and mucosa, the anatomical and functional restoration of the defect depend on which and what amount of tissues were provided to cover the defect; good aesthetic appearance subsequently follows the result. Furthermore, a simultaneous neck nodes dissection usually results in exposure of major neck vessels., which should be protected with sufficient padding. The ideal method to reconstruct a defect in the head and neck region requires a sufficient coverage by muscle layer with good vascularity, a wide arc of rotation, and minimization of donor site defect. The pectoralis major myocutaneous flap which was first decribed by Ariyan and lateral trapezius myocutaneous flap by Demergasso meet these criteria. We describe the use of these myocutaneous flaps in reconstruction of mandible and oral cavity.

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