• Title/Summary/Keyword: experimental warming

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Small Animal Small Animal $[^{18}F]$FDG PET Imaging for Tumor Model Study (종양 모델 연구를 위한 소동물 $[^{18}F]$FDG PET 영상화)

  • Woo, Sang-Keun;Kim, Kyeong-Min;Cheon, Gi-Jeong
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.1
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    • pp.1-7
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    • 2008
  • PET allows non-invasive, quantitative and repetitive imaging of biological function in living animals. Small animal PET imaging with $[^{18}F]$FDG has been successfully applied to investigation of metabolism, receptor-ligand interactions, gene expression, adoptive cell therapy and somatic gene therapy. Experimental condition of animal handling impacts on the biodistribution of $[^{18}F]$FDG in small animal study. The small animal PET and CT images were registered using the hardware fiducial markers and small animal contour point. Tumor imaging in small animal with small animal $[^{18}F]$FDG PET should be considered fasting, warming, and isoflurane anesthesia level. Registered imaging with small animal PET and CT image could be useful for the detection of tumor. Small animal experimental condition of animal handling and registration method will be of most importance for small lesion detection of metastases tumor model.

Effects of the Heated-Humidified Breathing Circuit Applied on the Body Temperature, Shivering, and Thermal Comfort of General Anesthesia Patients (가온가습호흡회로 적용이 전신마취 환자의 체온, 전율, 온도 편안감에 미치는 효과)

  • Son, Won Mi;Park, Jung Suk
    • Journal of East-West Nursing Research
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    • v.26 no.2
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    • pp.149-156
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    • 2020
  • Purpose: The purpose of this study was to identify the effects of the heated-humidified breathing circuit applied on the body temperature, shivering, and thermal comfort of general anesthesia patients. Methods: The participants were patients who received general anesthesia at University Hospital K located in City B, with 25 patients in the experimental group and 25 patients in the control group. The period of this study was from Mar 19 to Apr 26, 2019. The experimental equipment included a heated-humidified breathing circuit, which connects the intubation tube with the anesthesia machine for mechanical ventilation after airway intubation in general anesthesia patients. Results: The body temperature, shivering, and thermal comfort after surgery were significantly different between the two groups (p<.001). However, the body temperature during surgery was slightly different between the experimental group and the control group. Conclusion: A heated-humidified breathing circuit may be actively used in a warming method to prevent the hypothermia of general anesthesia patients.

Effect of Experimental Fluoride Varnish upon the Vickers Hardness of Bovine Teeth (실험용 불소바니쉬가 우치의 비커스 경도에 미치는 영향)

  • Kim, Ah-Jin;Son, Ju-Lee;Oh, Seunghan;Bae, Ji-Myung
    • Korean Journal of Dental Materials
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    • v.43 no.1
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    • pp.81-89
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    • 2016
  • The purpose of this study was to evaluate the effect of the experimental and commercial fluoride varnishes on the Vickers hardness of bovine teeth. The experimental fluoride varnishes with 5 wt.% NaF were fabricated using Bis-GMA or rosin as the resin base. The components were mixed with over-head stirrer under warming up in a double boiler for 30 minutes. Four commercial fluoride varnishes (V-varnish, Flor-opal, Cavity shield, Fluor protector) were compared with the experimental fluoride varnishes. Vickers hardness was measured on the labial surface of bovine anterior teeth after applying fluoride varnish on 5th and 30th day. The surface of bovine teeth was observed with a scanning electron microscope before and after applying fluoride varnish and the change of the components on the bovine teeth surface was measured with EDX. In terms of hardness, the experimental rosin-based fluoride varnish showed significantly higher hardness on the 5th and 30th day than the control (bovine teeth without fluoride treatment)(p<0.05). EDX results showed that the fluoride content on the surface of bovine teeth treated with the experimental rosin-based fluoride varnish was highest on the 1st and 10th day. The higher hardness and fluoride content of experimental rosin-based fluoride varnish can be considered to be used as an effective fluoride varnish to prevent dental caries.

A Study on the Performance Characteristics of the High Temperature Heat Storage Tank using MgO Materials (MgO를 사용한 고온축열탱크의 성능특성에 관한 연구)

  • Cho, So-Ang;Shin, Chang-Hoon;Lee, Su-Sang;Yoon, Seok-Hoon
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.17 no.4
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    • pp.413-418
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    • 2011
  • The global warming by abuse of fossil fuel is going to become an important problem which must be solved by human beings. This research is to develop a high temperature heat storage tank with high efficiency and to investigate the performance characteristics of this tank to help these energy problem. But the researches for this area have not been enough until now and specially the researches for high temperature heat storage tank are very few. For this research, heat storage bricks were made using MgO powder and studied about the performance characteristics of high temperature heat storage tank by experimental method. Through this research, it was confirmed that MgO can be used as a heat storage material for high temperature range.

Effects of supplementation with antifreeze proteins on the follicular integrity of vitrified-warmed mouse ovaries: Comparison of two types of antifreeze proteins alone and in combination

  • Kim, Min Kyung;Kong, Hyun Sun;Youm, Hye Won;Jee, Byung Chul
    • Clinical and Experimental Reproductive Medicine
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    • v.44 no.1
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    • pp.8-14
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    • 2017
  • Objective: The aim of this study was to analyze the effect of supplementing vitrification and warming solutions with two types of antifreeze proteins (AFPs) and the combination thereof on the follicular integrity of vitrified-warmed mouse ovaries. Methods: Ovaries (n=154) were obtained from 5-week-old BDF1 female mice (n=77) and vitrified using ethylene glycol and dimethyl sulfoxide with the supplementation of 10 mg/mL of Flavobacterium frigoris ice-binding protein (FfIBP), 10 mg/mL of type III AFP, or the combination thereof. Ovarian sections were examined by light microscopy after hematoxylin and eosin staining, and follicular intactness was assessed as a whole and according to the type of follicle. Apoptosis within the follicles as a whole was detected by a terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick-end labeling assay. Results: The proportion of overall intact follicles was significantly higher in the type III AFP-supplemented group (60.5%) and the combination group (62.9%) than in the non-supplemented controls (43.8%, p<0.05 for each). The proportion of intact primordial follicles was significantly higher in the FfIBP-supplemented (90.0%), type III AFP-supplemented (92.3%), and combination (89.7%) groups than in the non-supplemented control group (46.2%, p<0.05 for each). The proportions of non-apoptotic follicles were similar across the four groups. Conclusion: Supplementation of the vitrification and warming solutions with FfIBP, type III AFP, or the combination thereof was equally beneficial for the preservation of primordial follicles in vitrified mouse ovaries.

Variation of Ecological Niche of Quercus serrata under Elevated $CO_2$ Concentration and Temperature ($CO_2$ 농도 및 온도 상승에 의한 졸참나무의 생태적 지위 변화)

  • Cho, Kyu-Tae;Jeong, Heon-Mo;Han, Young-Sub;Lee, Seung-Hyuk
    • Korean Journal of Environmental Biology
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    • v.32 no.2
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    • pp.95-101
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    • 2014
  • In order to investigate effects of elevated $CO_2$ concentration and temperature on the ecological niche of Quercus serrata in Korea. We divided experimental condition in the greenhouse that are control (ambient condition) and treatment with elevated $CO_2$ (approximately 1.6 above than control) and increased air temperature (approximately $2.2^{\circ}C$ above than control). We measured twenty kind characters of seedlings and calculated the ecological niche breadth. As a result, the ecological niche breadth, treatment was widened in the light gradient than the control, was narrowed in the moisture and nutrient gradient. This is may be predicted when the global warming progress, Q. serrata is increases resistance to light environment, and decrease resistance to moisture and nutrient environment. According to the principal component analysis (PCA), control and treatment were arranged based on factor 1 and 2 in each environment gradients. Ecological response is involved variety characters. Among them, indicating that Characters of production is involved in many a parts.

Performance Evaluation of R435A on Refrigeration System of Water Purifiers (R435A를 적용한 정수기 냉동시스템의 성능평가)

  • Lee, Yo-Han;Kang, Dong-Gyu;Choi, Hyun-Joo;Jung, Dong-Soo
    • Journal of the Korean Solar Energy Society
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    • v.33 no.1
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    • pp.15-23
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    • 2013
  • In this study, thermodynamic performance of R435A is examined both numerically and experimentally in an effort to replace HFC134a used in the refrigeration system of domestic water purifiers. Even though HFC134a is used predominantly in such a system these days, it needs to be phased out in the near future in Europe and most of the developed countries due to its high global warming potential. To solve this problem, cycle simulation and experimental measurements are carried out with a new refrigerant mixture of 20%R152a/80%RE170 using actual domestic water purifiers. This mixture is numbered and listed as R435A by ASHRAE recently. Test results show that the system performance with R435A is greatly influenced by the amount of charge due to the small internal volume of the refrigeration system of the domestic water purifiers. With the optimum amount of charge of 21 to 22 grams, about 50% of HFC134a, the energy consumption of R435A is 11.8% lower than that of HFC134a. The compressor discharge temperature of R435A $8^{\circ}C$ lower than that of HFC134a at the optimum charge. Overall, R435A, a new long term environmentally safe refrigerant, is a good alternative for HFC134a requiring little change in the refrigeration system of the domestic water purifiers.

Performance of R430A on Refrigeration System of Domestic Water Purifiers (대체냉매 R430A를 적용한 정수기 냉동시스템의 성능 평가)

  • Park, Ki-Jung;Lee, Yo-Han;Jung, Dong-Soo;Kim, Kyoung-Kee
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.21 no.2
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    • pp.109-117
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    • 2009
  • In this study, thermodynamic performance of R430A is examined both numerically and experimentally in an effort to replace HFC134a used in the refrigeration system of domestic water purifiers. Even though HFC134a is used predominantly in such a system these days, it needs to be phased out in the near future in Europe and most of the developed countries due to its high global warming potential. To solve this problem, cycle simulation and experimental measurements are carried out with a new refrigerant mixture of 76%R152a124% R600a using actual domestic water purifiers. This mixture is numbered and listed as R430A by ASHRAE recently. Test results show that the system performance with R430A is greatly influenced by the amount of charge due to the small internal volume of the refrigeration system of the domestic water purifiers. With the optimum amount of charge of 21 to 22 grams, about 50% of HFC134a, the energy consumption of R430A is 13.4% lower than that of HFC 134a. The compressor dome and discharge temperatures and condenser center temperature of R430A are very similar to those of HFC134a at the optimum charge. Overall, R430A, a new long term environmentally safe refrigerant, is a good alternative for HFC134a requiring little change in the refrigeration system of the domestic water purifiers.

Effects of ASPAN's Evidence-based Clinical Practice Guidelines for Promotion of Hypothermia of Patients with Total Knee Replacement Arthroplasty (슬관절 전치환술 환자의 저체온 관리를 위한 ASPAN의 근거기반 임상실무 가이드라인 적용 효과)

  • Yoo, Je Bog;Park, Hyun Ju;Chae, Ji Yeoun;Lee, Eun Ju;Shin, Yoo Jung;Ko, Justin Sangwook;Kim, Nam Cho
    • Journal of Korean Academy of Nursing
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    • v.43 no.3
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    • pp.352-360
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    • 2013
  • Purpose: In this study an examination was done of the effects of the American Society of PeriAnesthesia Nurses (ASPAN) Evidence-Based Clinical Practice Guidelines on body temperature, shivering, thermal discomfort, and time to achieve normothermia in patients undergoing total knee replacement arthroplasty (TKRA) under spinal anesthesia. Methods: This study was an experimental study with a randomized controlled trial design. Participants (n=60) were patients who underwent TKRA between December 2011 and March 2012. Experimental group (n=30) received active and passive warming measures as described in the ASPAN's guidelines. Control group (n=30) received traditional care. Body temperature, shivering, thermal discomfort, time to achieve normothermia were measured in both groups at 30 minute intervals. Results: Experimental group had slightly higher body temperature compared to control group (p=.002). Thermal discomfort was higher in the experimental group before surgery but higher in the control group after surgery (p=.034). It decreased after surgery (p=.041) in both groups. Time to achieve normothermia was shorter in the experimental group (p=.010). Conclusion: ASPAN's guidelines provide guidance on measuring patient body temperature at regular intervals and on individualized and differentiated hypothermia management which can be very useful in nursing care, particularly in protecting patient safety and improving quality of nursing.

The Effect of Dance Therapy on Pulmonary and Cognitive Function in the Elderly (무용요법이 노인의 폐기능과 인지기능에 미치는 효과)

  • 이영란;유숙자
    • Journal of Korean Academy of Nursing
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    • v.29 no.6
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    • pp.1273-1283
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    • 1999
  • This study was done to explore the effects of dance therapy on pulmonary and cognitive functions in the elderly. The design of this study was a non-equivalent pre-post test experiment. The subjects consisted of elderly persons living in a facility located in Kyoungi-Do. Fifty eight subjects had normal cognition, sensory function and resting blood pressure. They underwent tests of pulmonary and cognitive function as baseline data before dance therapy, and at 6th week and at the end of 12nd week after following dance therapy. Twenty seven elderly persons were assigned to the experimental group and participated with the dance therapy. This therapy was based on the Marian Chace's dance therapy and Korean traditional dance with music. The dance therapy consisted of 50 minutes session, 3 times a week for 12 weeks. One session consisted of warming-up, expression, catharsis, sharing and closing stage. the intensity of the dance therapy was at the 40% of age-adjusted maximum heart rates. Data were analyzed with mean, standard deviation, Chi-square test, unpaired t-test, repeated measures ANOVA, and Bonferroni multiple regression using SAS program. The results were as follows : 1. Pulmonary function(forced expiratory volume at one second and forced vital capacity) of the experimental subjects significantly increased over time more than that of the control subjects. 2. The experimental group had significantly higher score for pulmonary function than the control group at the 12nd week after dance therapy. 3. Cognitive function of the experimental subjects significantly increased over time more than that of the control subjects. 4. The experimental group had significantly higher score for cognitive function than the control group at the 6th week and 12nd week after dance therapy. The findings showed the dance therapy could be effective in improving the pulmonary and cognitive function of the elderly.

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