• Journal of Digital Convergence
• /
• v.16 no.2
• /
• pp.375-383
• /
• 2018

The purpose of this study was to investigate the effect of exercise training on health-related physical fitness and osteoporosis after 12 weeks of combined training for adults with intellectual disabilities diagnosed with obesity and osteoporosis. The subjects conducted a combined training program consisting of aerobic exercise and strength training twice a week for 12 weeks. Body composition and bone mineral density were measured before exercise, 6, 12 weeks, and health-related physical fitness was measured before and after exercise. Body weight and body fat decreased after exercise and bone density increased after exercise compared to before exercise. Muscle strength, muscle endurance and flexibility were improved after exercise compared to before exercise. It was confirmed that the 12 week compound training increased the leg strength and improved the functions such as walking and running, and increased the health-related fitness and increased bone mineral density.

• Journal of Korean Physical Therapy Science
• /
• v.26 no.3
• /
• pp.1-7
• /
• 2019

Purpose: The purpose of this study was to investigate the effects of the Otago exercise combined with action observation training on changes of the brain activity of the elderly. Design: Randomized controlled trial. Methods: Thirty elderly women in the experiment were included. Participants were randomly assigned to the Otago combined with action observation training group, the Otago exercise group, and the control group (10 in each group). The Otago combined with action observation training group and the Otago exercise group performed the strength and balance exercises of the Otago exercise program for 50 minutes three times a week for 12 weeks. The Otago combined with action observation training group underwent additional action observation training for the Otago movement for 20 minutes three times a week. No intervention was performed in the control group. PolyG-1 (LAXTHA Inc., Daejeon, Korea) was used to measure the changes in the brain activity following intervention. One-way analysis of variance was used to compare the effects among the groups and a post-hoc test was performed. Results: The relative mu rhythms in the F3, C3, and C4 regions were significantly increased in the Otago combined with action observation training group. Relative beta wave activity in the Fp1, F3, F3, and C3 regions was significantly increased in the Otago combined with action observation training group (p<0.05). Conclusion: The results indicated that the Otago exercise combined with action observation training was effective for promoting the brain activity of the elderly.

• Journal of Korean Physical Therapy Science
• /
• v.17 no.1_2
• /
• pp.1-9
• /
• 2010

Background: The objective of this study was to determine whether sensorimotor training using an unstable surface affects dynamic balance and gait function in patients with hemiparesis, and to compare the effect of sensorimotor training with that of cycling exercise. Methods: Two subjects with post-stroke hemiparesis volunteered to participate in this study. Single-subject A-B design with alternating treatment was used for this study. Baseline(A) and intervention(B) phases were performed for 7 and 8 sessions, respectively. Sensorimotor training and cycling exercise were performed for 20 minutes in randomized order. Assessment tools were made by using a step test, timed up and go(TUG) test, and 6-minute walk test(6MWT). Results: Each of the participants improved in all three tests after the two interventions. Participants 1 and 2 showed the improvement for their assessment score after sensorimotor training in the step test by 42.1%(p<.05) and 58%, in the TUG, 31% and 19.5%, and in the 6MWT test, 32.3% and 10.6%(p<.05), respectively. After cycling exercise, participants 1 and 2 also improved in the step test by 32.5% and 53.1%, in the TUG, 27.4% and 18%, and in the 6MWT test, 28.8% and 3%. In statistical analysis between the two interventions, sensorimotor training showed a significant increased values in the step test for participant 1 and the 6MWT for participant 2 as compared with those of cycling exercise. Conclusion: Sensorimotor training and cycling exercise are helpful for improving dynamic balance and gait capacity. Furthermore, sensorimotor training may be more helpful than cycling exercise.

• Journal of Korean Biological Nursing Science
• /
• v.3 no.1
• /
• pp.29-40
• /
• 2001

The purpose of this study was to investigate the effect of exercise training on work capacity, psychologic functions and quality of life in hemodialysis patients. Forteen hemodialysis patients, 3 males, 11 females, age ranged from $23{\sim}58$ years($42.3{\pm}0.4$) were selected and assessed using a modified Bruce protocol on a treadmill. The 3 months supervised exercise training consisted of 60 minites session thrice weekly on the treadmill, bicycle and arm ergometer at $40{\sim}60%$ of maximum $O_2$ consumption. The changes of maximum $O_2$ consumption, psychologic test and quality of life questionnaire in 14 patients before and after 3 months exercise training have been measured. The mean maximum $O_2$ consumption($VO_2$ max) of exercises increased by 23% after training(pre-and postexercise $26.3{\pm}4.6ml$/kg/min vs $29.8{\pm}4.9ml$/kg/min, p=0.013). There was significant reduction in anxiety score(p=0.004) and significant improvement in quality of life score(p=0.031) after training. The result of this study indicated that a structured exercise training for hemodialysis patients provides many benefits. These result suggest the exercise training can improve the work capacity, psychologic functions and quality of life outcomes in hemodialysis patients.

• The Korean Journal of Physiology and Pharmacology
• /
• v.21 no.6
• /
• pp.633-641
• /
• 2017

The aim of this study is to investigate the effects of intermittent ladder-climbing exercise training on mitochondrial biogenesis and ER stress of the cardiac muscle in high fat diet-induced obese middle-aged rats. We induced obesity over 6 weeks of period in 40 male Sprague-Dawley rats around 50 weeks old, and were randomly divided into four experimental groups: chow, HFD, exercise+HFD, and exercise+chow. The exercising groups underwent high-intensity intermittent training using a ladder-climbing and weight exercise 3 days/week for a total of 8 weeks. High-fat diet and concurrent exercise resulted in no significant reduction in body weight but caused a significant reduction in visceral fat weight (p<0.05). Expression of $PPAR{\delta}$ increased in the exercise groups and was significantly increased in the high-fat diet+exercise group (p<0.05). Among the ER stress-related proteins, the expression levels of p-PERK and CHOP, related to cardiac muscle damage, were significantly higher in the cardiac muscle of the high-fat diet group (p<0.05), and were significantly reduced by intermittent ladder-climbing exercise training (p<0.05). Specifically, this reduction was greater when the rats underwent exercise after switching back to the chow diet with a reduced caloric intake. Collectively, these results suggest that the combination of intermittent ladder-climbing exercise training and a reduced caloric intake can decrease the levels of ER stress-related proteins that contribute to cardiac muscle damage in obesity and aging. However, additional validation is required to understand the effects of these changes on mitochondrial biogenesis during exercise.

• Journal of Life Science
• /
• v.27 no.3
• /
• pp.361-369
• /
• 2017

Mitochondrial homeostasis is tightly regulated by two major processes: mitochondrial biogenesis and mitochondrial degradation by autophagy (mitophagy). Research in mitochondrial biogenesis in skeletal muscle in response to endurance exercise training has been well established, while the mechanisms regulating mitophagy and the relationship between mitochondrial biogenesis and degradation following endurance exercise training are not yet well defined. Studies have demonstrated that endurance exercise training increases the expression levels of mitochondrial biogenesis-, dynamics-, mitophagy-related genes in skeletal muscle. However, the increased levels of mitochondrial biogenesis marker proteins such as Cox IV and citrate synthase, by endurance exercise training were abolished when autophagy/mitophagy was inhibited in skeletal muscle. This suggests that both autophagy/mitophagy plays an important role in mitochondrial biogenesis/homeostasis and the coordination between the opposing processes may be important for skeletal muscle adaptation to endurance exercise training to improve metabolic function and endurance exercise performance. It is considered that endurance exercise training regulates each of these processes, mitochondrial biogenesis, fusion and fission events and autophagy/mitophagy, ensuring a relatively constant mitochondrial population. Exercise training may also have contributed to mitochondrial quality control which replaces old and/or unhealthy mitochondria with new and/or healthy ones in skeletal muscle. In this review paper, the molecular mechanisms regulating mitochondrial biogenesis and mitophagy and the coordination between the opposing processes is involved in the cellular adaptation to endurance exercise training in skeletal muscle will be discussed.

• Journal of International Academy of Physical Therapy Research
• /
• v.7 no.1
• /
• pp.915-918
• /
• 2016

The purpose of this study was to assess the effects of Ankle exercise on balance ability of stroke patients. Participants' balance ability were measured prior to the training and they conducted ankle exercise. As for ankle exercises, ankle stretching training and ankle muscle strengthening training were performed for 10 minutes respectively. They did warm up exercise for 5 minutes and then ankle exercise for 20 minutes. And then they did cooldown exercise for 5 minutes. Their balance ability was measured after 9 weeks. According to the results of analyzing the change of balance ability that timed up and go and Berg balance scale score significantly improved but in the control group it did not significantly decrease. In comparison between the groups, Berg balance scale score significantly improved in the ankle exercise group compared to the control group. Ankle exercise performed by stroke patients are considered to be effective in improving balance ability.

• Physical Therapy Korea
• /
• v.13 no.3
• /
• pp.18-23
• /
• 2006

The limited walking ability after a stroke restricts a patient's independent mobility at home and in the community. It also brings about significant social handicaps. Therefore, it is necessary to improve walking ability in community-dwelling persons with stroke. The purpose of this study was to evaluate the effectiveness of gait training and muscle strengthening exercise of lower extremities in persons with chronic stroke. Nineteen community-dwelling individuals with stroke participated in this program. The exercise program lasted for seven weeks, with a 1-hour program twice per week, and it consisted of balance training, gait training, and strengthening of lower extremities. The outcome of the program was assessed by the gait speed, Wisconsin Gait Scale (WGS), Berg Balance Scale (BBS), and Stroke Impact Scale (SIS). Significant effects were found for the WGS, BBS, and mobility and hand function domain of the SIS (p<.05). It was found that short-term gait training exercise could improve quality of gait, balance, and mobility. Therefore, a more effective exercise program is required for community-based persons with stroke.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.15 no.1
• /
• pp.367-376
• /
• 2014

The purpose of this study was to investigate the effect of either endurance training only or endurance and weight training on muscle morphology and oxidative enzyme activities in human skeletal muscles. Fourteen healthy males were randomly divided into one of two experimental training groups, either swim exercise training (n=7, ST) or combined exercise training (swim and resistance exercise training; n=7, SWT). The change of muscle fiber type was not significantly different between ST and SWT following 6 weeks of exercise training. Mean cross sectional areas as well as the numbers of capillary of different types of muscle fiber were not also significantly different from baseline for both exercise training groups (p>.05) although the tendency of increase were more notable in SWT. All oxidative enzyme activities (i.e., ${\beta}$-hydroxyl acyl dehydrogenase, citrate synthase, and carnitine palmitoyl transferase) were marginally higher in SWT compared to ST even though statistical power did not reach the level of significance. Based on these results, it was concluded that performing of combined (swimming and weight) exercise training could be the better modality for improving muscle morphological changes and oxidative enzyme activities than performing of only single aerobic exercise intervention in young healthy human skeletal muscles.

• Journal of Korean Physical Therapy Science
• /
• v.2 no.4
• /
• pp.779-783
• /
• 1995

The number of the subjects of this study were all sixteen including 8 male and 8 female. They were chronic low back pain patients and treated at hospital out patient. The patients took lumbar extension strength training. The results of examination and analysis isometric lumbar extension muscular strength before and after the training are as follows; 1. TFT increased after lumbar extension muscular strength exercise than before the exercise. Inspire of difference of each angle. The reciprocal action didn't happen between training and angle. 2. NMT increased after lumbar extension muscular strength exercise than the before the exercise and the difference of each angle didn't happen. The reciprocal action also didn't happen between the training and angle. 3. Comparing presented standard point with individual point, 13persons' muscle strength of first step increased, on the other and 3 person's muscle strength a little increased in a same category. 4. The grade of low back pain decreased for all subjects. Concluding this study, lumbar extension muscular strength exercise through isokinetic device decreases the grade of low back pain and increase lumbar extension muscular strength. It is that equal exercise effect happen in full range of motion, for the exercise effect doesn't show the difference of each angle.