• 한국학교보건학회지
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• 제18권2호
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• pp.73-84
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• 2005

Purpose : This study was designed to apply a "stage of change" exercise intervention program to obese children in elementary school and to examine its effects on their BMI. stage of change. process . and self-efficacy in exercise. Methods : The experimental group included 64 children in the fourth . fifth and sixth grades. from one elementary school. whose BMI was in the H5th percentile or more for their age groups. The control group had 6 1 students from a different one elementary school whose conditions were the same as those of the experimental group. Results: After the stage of change exercise intervention was applied, the BMI of the experimental group decreased by a significant enough degree to conclude that the program was effective in decreasing BMI. After the application of the program. the experimental group experienced a significant increase in their helping relationships. counter-conditioning . reinforcement management and stimulus control compared 10 the control group. After the program. self-efficacy in terms of exercise increased significantly in the experimental group. Conclusion: A stages of change exercise intervention program has been shown to engage individual students and encourage them 10 maintain a higher fitness level that promote s self-efficacy in exercise and therefore moves them towards healthier lifestyles. Moreover. the study proved that a significant reduction of BMI was achieved by the stages of change exercise intervention program.

• The Journal of Korean Physical Therapy
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• 제21권3호
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• pp.53-59
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• 2009

Purpose: The purpose of this study was to investigate the effects of proprioceptive exercise on the body alignment of elderly women. Method: The experimental group consisted of twenty elderly women who participated in proprioceptive exercise for 8 weeks. The subjects were measured using Global Posture System equipment for assessing their body alignment. Body alignment was measured at the ear, shoulder joint, knee joint and calcaneocuboid joint on the sagittal plane, and the left and right acromion process positions, the ASIS and the medial malleoulus on the coronal plane. The body alignment data was used to assess the changes before and after proprioceptive exercise. The data of the experimental group was compared and analyzed using the Wilcoxon singed-rank test between before and after proprioceptive exercise. The Mann-Whithney test was used to compare the experimental group and the control group. Result: The result of this study was that the body alignment of the experimental group at the ear and knee joint on the sagittal plane was significantly in alignment with the line of gravity (p<0.05) before and after proprioceptive exercise. The body alignment was statistically different (p<0.05) between the experimental group and the control group on the frontal plane and sagittal plane. Conclusion: This study showed that proprioceptive exercise does affect the body alignment in elderly women. This indicates that there is interaction that plays a crucial role for proprioceptive stimuli and the body alignment.

• Journal of Community Nutrition
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• 제4권3호
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• pp.187-194
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• 2002

This study was investigated the effects of exercise and supplementation of L-carnitine and antioxidants on hepatic mitochondrial function, especially oxidative phosphorylation (OXPHOS). Isolated hepatic mitochondria from 4 rat groups were functionally tested by an analysis of respiration and the coupling of this process to ATP synthesis in the presence of ADP. Four groups were non-trained, non-supplemented group (NTNS), non-trained, supplemented group (NTS), long term-trained, non-supplemented group (LTNS) , and long term-trained, supplemented group (LTS). The trained rats run on a treadmill (grade 10°,20 m/min) for 60min/day for 8 weeks. The supplemented rats were treated with L-carnitine (0.5% diet), vitamin E(0.5mg/g BW), vitamin C (0.5mg/g BW) and melatonin (1 $\mu$ g/g BW) for 8 weeks. There were exercise effects on improving mitochondrial OXPHOS. Within non-supplemented groups, exercised rats resulted in a significant decrease in state 4 oxygen consumption, which increased the respiratory control (RC) ratio and ADP : O (P/O) ratio. There were supplementation effects on improving mitochondrial OXPHOS, too. Within non-exercised rats, supplemented rats resulted in a significant decrease in state 4 oxygon consumption. which increased the RC ratio and P/O ratio. There were additive effects of exercise and supplementation on OXPHOS. Within supplemented rats, exercise resulted in an increase in RC ratio. Significant effects of exercise-supplement interaction on improving OXPHOS were identified. It suggests that exercise and supplementation of L-carnitine and antioxidants might improve more efficiently the impaired OXPHOS efficiency in mitochondrial dysfunction that recognized as is an important cause of degenerative diseases. (J Community Nutrition 4(3) : 187∼194, 2002)

• Journal of Animal Science and Technology
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• 제58권4호
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• pp.17.1-17.7
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• 2016

Background: The Sapsaree (Canis familiaris) is a Korean native dog that is very friendly, protective, and loyal to its owner, and is registered as a natural monument in Korea (number: 368). To investigate large-scale gene expression profiles and identify the genes related to exercise-induced stress in the Sapsaree, we performed whole-transcriptome RNA sequencing and analyzed gene expression patterns before and after exercise performance. Results: We identified 525 differentially expressed genes in ten dogs before and after exercise. Gene Ontology classification and KEGG pathway analysis revealed that the genes were mainly involved in metabolic processes, such as programmed cell death, protein metabolic process, phosphatidylinositol signaling system, and cation binding in cytoplasm. The ten Sapsarees could be divided into two groups based on the gene expression patterns before and after exercise. The two groups were significantly different in terms of their basic body type ($p{\leq}0.05$). Seven representative genes with significantly different expression patterns before and after exercise between the two groups were chosen and characterized. Conclusions: Body type had a significant effect on the patterns of differential gene expression induced by exercise. Whole-transcriptome sequencing is a useful method for investigating the biological characteristics of the Sapsaree and the large-scale genomic differences of canines in general.

• 전기전자학회논문지
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• 제23권1호
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• pp.74-79
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• 2019

인구 고령화와 웰빙 열풍으로 인해 건강관리 욕구가 증가하면서 피트니스에 대한 관심은 점점 더 높아지고 있다. 사람들은 운동을 하기 위해 헬스장을 가지만, 많은 이들이 운동하는 방법을 몰라 운동 순서나 운동 자세를 틀리게 하는 경우가 많다. 이러면 운동 효과도 미비할 뿐만 아니라 부상의 위험도 커진다. 본 논문에서는 스마트 거울 앞에서 영상을 보며 혼자서 운동을 따라 할 수 있고 운동 자세가 잘못되었을 경우 실시간으로 틀린 곳을 확인시켜주는 스마트 거울을 활용한 피트니스 시스템의 개발 내용에 대해 기술한다. 이 시스템을 사용함으로써 사람들은 혼자서도 트레이너의 도움 없이 바른 자세로 운동을 할 수 있게 될 것이며, 이로 인해 그룹 또는 개인 트레이너를 기다려야 하는 시간이나 비용의 제약에 얽매이지 않고 운동을 할 수 있게 될 것이다.

• 운동영양학회지
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• 제25권4호
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• pp.38-44
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• 2021

[Purpose] Exercise can prevent conditions such as atrophy and degenerative brain diseases. However, owing to individual differences in athletic ability, exercise supplements can be used to improve a person's exercise capacity. Schisandra chinensis (SC) is a natural product with various physiologically active effects. In this study, we analyzed SC using a pharmacological network and determined whether it could be used as an exercise supplement. [Methods] The active compounds of SC and target genes were identified using the Traditional Chinese Medicine Database and Analysis Platform (TCMSP). The active compound and target genes were selected based on pharmacokinetic (PK) conditions (oral bioavailability (OB) ≥ 30%, Caco-2 permeability (Caco-2) ≥ -0.4, and drug-likeness (DL) ≥ 0.18). Gene ontology (GO) was analyzed using the Cytoscape software. [Results] Eight active compounds were identified according to the PK conditions. Twenty-one target genes were identified after excluding duplicates in the eight active compounds. The top 10 GOs were analyzed using GO-biological process analysis. GO was subsequently divided into three representative categories: postsynaptic neurotransmitter receptor activity (53.85%), an intracellular steroid hormone receptor signaling pathway (36.46%), and endopeptidase activity (10%). SC is related to immune function. [Conclusion] According to the GO analysis, SC plays a role in immunity and inflammation, promotes liver metabolism, improves fatigue, and regulates the function of steroid receptors. Therefore, we suggest SC as an exercise supplement with nutritional and anti-fatigue benefits.

• 운동영양학회지
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• 제25권3호
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• pp.28-35
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• 2021

[Purpose] As Panax ginseng C. A. Meyer (ginseng) exhibits various physiological activities and is associated with exercise, we investigated the potential active components of ginseng and related target genes through network pharmacological analysis. Additionally, we analyzed the association between ginseng-related genes, such as the G-protein-coupled receptors (GPCRs), and improved exercise capacity. [Methods] Active compounds in ginseng and the related target genes were searched in the Traditional Chinese Medicine Database and Analysis Platform (TCMSP). Gene ontology functional analysis was performed to identify biological processes related to the collected genes, and a compound-target network was visualized using Cytoscape 3.7.2. [Results] A total of 21 ginseng active compounds were detected, and 110 targets regulated by 17 active substances were identified. We found that the active compound protein was involved in the biological process of adrenergic receptor activity in 80%, G-protein-coupled neurotransmitter in 10%, and leucocyte adhesion to arteries in 10%. Additionally, the biological response centered on adrenergic receptor activity showed a close relationship with G protein through the beta-1 adrenergic receptor gene reactivity. [Conclusion] According to bioavailability analysis, ginseng comprises 21 active compounds. Furthermore, we investigated the ginseng-stimulated gene activation using ontology analysis. GPCR, a gene upregulated by ginseng, is positively correlated to exercise. Therefore, if a study on this factor is conducted, it will provide useful basic data for improving exercise performance and health.

• 운동영양학회지
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• 제23권3호
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• pp.13-21
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• 2019

[Purpose] Chronic stress is a precipitating factor for depression, whereas exercise is beneficial for both the mood and cognitive process. The current study demonstrates the anti-depressive effects of regular exercise and the mechanisms linked to hippocampal neurogenesis. [Methods] Mice were subjected to 14 consecutive days of restraint, followed by 3 weeks of treadmill running, and were then subjected to behavioral tests that included the forced swimming and Y-maze tests. Protein levels were assessed using western blot analysis and newborn cells were detected using 5-bromo-2'-deoxyuridine (BrdU). [Results] Three weeks of treadmill running ameliorated the behavioral depression caused by 14 days of continuous restraint stress. The exercise regimen enhanced BrdU-labeled cells and class III β-tubulin levels in the hippocampal dentate gyrus, as well as those of thioredoxin-1 (TRX-1) and synaptosomal β2-adrenergic receptors (β2-AR) under stress. In vitro experiments involving treatment with recombinant human TRX-1 (rhTRX-1) augmented the levels of phospho-extracellular signal-regulated kinases 1 and 2 (ERK1/2), nuclear β-catenin, and proliferating cell nuclear antigens, which were previously inhibited by U0216 and FH535 (inhibitors of ERK1/2 and β-catenin/T cell factor-mediated transcription, respectively). The hippocampal neurogenesis elicited by a 7-day exercise regimen was abolished by a selective inhibitor of β2-AR, butoxamine. [Conclusion] These results suggest that TRX-1-mediated hippocampal neurogenesis by β2-AR function is a potential mechanism underlying the psychotropic effect of exercise.

• 정보보호학회논문지
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• 제30권5호
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• pp.805-821
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• 2020

사이버 방어 훈련은 최신 사이버공격을 고려한 훈련을 수행해야 할 뿐만 아니라 사이버공격 대응 과정이 실전과 유사해야 그 효과가 크다고 할 수 있다. 또한 최근에는 사이버공격에 관계없이 정상업무를 수행하거나 그에 준하는 업무를 지원할 수 있는 사이버 회복력에 대한 훈련 역시 중요하다. 이에 본 논문에서는 국내에서 사이버공격 발생 시 발령되는 사이버위기 경보를 기반으로 실시간 사이버훈련을 수행함으로 사이버 회복력의 요소들을 강화시킬 수 있는 사이버 방어 훈련장을 제안한다. 사이버위기 경보 수준에 따라 관심·주의·경계·심각 경보 발령 시, 사이버 방어 훈련장은 해당 경보에 따라, 보안 요소를 점검하는 예방보안, 실시간으로 사이버공격 방어를 수행하는 실시간대응, 피해 시스템의 사고조사를 수행하는 사후대응 훈련을 수행할 수 있는 환경을 지원한다. 본 논문에서 제안하는 사이버 방어 훈련장은 사이버위기 환경에서 국내 실정에 맞는 사이버 방어 훈련을 수행함으로써 훈련생들이 사이버위협에 대한 실질적인 대응 역량을 제고 할 수 있다.

• 한국노년학
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• 제29권2호
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• pp.657-667
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• 2009

본 연구는 규칙적인 유산소 운동이 성장에 따른 세포 복제현상에 미치는 영향을 살펴보기 위하여 염색체 말단에 위치한 텔로미어의 길이와 결합단백질인 TRF 2(telomere repeat binding factor 2)의 발현량을 분석하였다. 흰쥐를 대상으로 장기간 운동집단, 단기간 운동집단, 비교집단 그리고 기준수준 검증을 위한 기준집단의 4집단으로 각각 7마리씩 총28마리를 배정하였으며, 수영 운동은 무부하 자유유영의 형태로 주 5회, 매회 1시간씩 실시하였다. 마지막 운동 종료 후 24시간 뒤 쥐를 희생시켜 심장, 간, 가자미근을 적출하여 genomic DNA를 추출, 텔로미어의 길이와 관련단백질인 TRF 2의 발현량을 분석하였다. 연구 결과, 간조직의 텔로미어 길이와 TRF 2 단백질의 발현량은 집단 간 차이를 발견할 수 없었으나, 심장조직의 텔로미어 길이는 장기간 운동집단이 비교집단 및 단기간 운동집단에 비해 길게 나타났고, TRF 2의 단백질 발현 또한 높게 나타나, 장기간의 수영 운동이 성장에 따른 심장의 텔로미어 단축현상을 지연시키는 효과가 있는 것으로 나타났다. 또한, 가자미근에서는 4주령의 기준집단에 비해 비교집단과 단기간 운동집단의 텔로미어의 길이는 유의하게 짧았으나, 장기간 운동집단과는 유의한 차이가 나타나지 않은 것으로 미루어 장기간의 수영 운동이 골격근의 복제적 노화현상도 억제할 수 있는 가능성을 관찰할 수 있었다.