• The Korean Journal of Physiology and Pharmacology
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• v.22 no.3
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• pp.235-248
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• 2018

Ursolic acid (UA) is a natural triterpene compound found in various fruits and vegetables. There is a growing interest in UA because of its beneficial effects, which include anti-inflammatory, anti-oxidant, anti-apoptotic, and anti-carcinogenic effects. It exerts these effects in various tissues and organs: by suppressing nuclear factor-kappa B signaling in cancer cells, improving insulin signaling in adipose tissues, reducing the expression of markers of cardiac damage in the heart, decreasing inflammation and increasing the level of anti-oxidants in the brain, reducing apoptotic signaling and the level of oxidants in the liver, and reducing atrophy and increasing the expression levels of adenosine monophosphate-activated protein kinase and irisin in skeletal muscles. Moreover, UA can be used as an alternative medicine for the treatment and prevention of cancer, obesity/diabetes, cardiovascular disease, brain disease, liver disease, and muscle wasting (sarcopenia). In this review, we have summarized recent data on the beneficial effects and possible uses of UA in health and disease managements.

• Journal of Yeungnam Medical Science
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• v.20 no.1
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• pp.36-44
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• 2003

Background: To evaluate the efficacy of EMG biofeedback and pelvic floor electrical stimulation in the stress urinary incontinence patients by Kontinence HMT2000. Materials and Methods: A group of 14 patients with stress urinary incontinence were treated with combined biofeedback and intravaginal electrical stimulation during 12 sessions from 2 weeks to 6 weeks. Results: At immediate post treatment, subjective cure rate was 28% and improvement rate was 57% and failure rate was 15%. Thus the overall success rate for this treatment was 85%. The result of 3 months after treatment showed cure rate 14% and improvement rate was 43%. Intravaginal pressure increased by an average of 11.9 cmH2O. Increased vaginal pressure was found in 93% of the patients and more than 50% increment of intravaginal pressure was 71%. Conclusions: Combined biofeedback and pelvic floor electrical stimulation by use of Kontinence HMT2000 is effective for the patients who have good compliance, relative low degree stress urinary incontinence. In order to attain good results, a well structured program that teaches specific muscle exercise and the patients should be followed by regular interval reinforcement treatment.

• The Journal of Internal Korean Medicine
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• v.25 no.4
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• pp.464-472
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• 2004

Aortic regurgitation occurs when there is a leakage of the valve backward into the left ventricle during diastole. Chronic aortic regurgitation may be present for decades before any symptoms occur. The left ventricle is able to compensate for the large volume of blood that flows backward by enlarging the cavity and increasing the thickness of the muscle. This mechanism allows the heart to pump out both the amount of blood required by the body and the blood that has gone backward into the left ventricle. One patient who had chest pain from exercise was treated. He was diagnosed with aortic regurgitation LVH by echocardiography. Signs showed him to be of Taeumin-type within Sasang Constitutional Medicine. He was prescribed Gamijoripewontang for 75 days, and improvement of clinical symptoms were observed. Results support prescription of Gamijoripewontang as an effective treatment for Taeumin-type patients suffering chest pain caused by aortic regurgitation.

• Journal of the Korean Society of Physical Medicine
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• v.10 no.3
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• pp.87-93
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• 2015

PURPOSE: The purpose of this study was to investigate the effects of the 8.5seconds cut-off of the 8-foot up-and-go test as a predictor of falling and a good discriminator of fallers and non-fallers in women in their 60s to 80s. METHODS: The final subjects of this study were 98 elderly women from six senior centers of B metropolitan city. The 8-foot up-and-go test evaluated agility and dynamic balance. The chair-stand test measured the muscle strength for of the lower body. Ankle dorsiflexion and plantar flexion were measured to assess the ankle mobility of the subjects in this study. RESULTS: The below 8.5seconds group showed significantly low values in age and high values in chair-stand (times/30 s), plantar flexion ($^{\circ}$), and K-MMSE (score) compared to the over 8.5seconds group. This group was significantly faster compared to the over 8.5seconds group. In the below 8.5seconds group, only plantar flexion ($^{\circ}$) of all the items showed significantly higher values among those in their 60s compared to those in their 70s and 80s. CONCLUSION: The 8.5seconds cut-off on the 8-foot up-and-go test as a good discriminator and predictor of falling showed differences among fall risk factors (age, lower extremity strength, cognition, and ankle mobility) in women in their 60s to 80s without having regular exercise and a fall experience over the past ones year.

• Journal of Haehwa Medicine
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• v.27 no.2
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• pp.1-10
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• 2018

Objectives : The purpose of this study is to investigate the latest trend of studies on treatments of postoperative rotator cuff tear patients which are published in Korea. Methods : We investigated the studies on the treatments of postoperative rotator cuff tear patients via searching 6(six) Korean web databases(NSDL, RISS, Korean traditional knowledge portal, OASIS, KISTI, KCI). As a result, 16(sixteen) studies were found. We classified the papers by publication date, published journal, method of study, type of treatment, evaluation scale and referencing research ethics. Results : 16(sixteen) papers were published from 2006 to 2017. The papers were published in The journal of Korean shoulder & elbow society, The journal of korean acupuncture & moxibustion medicine, etc. 5(five) randomized controlled trials, 5(five) non-randomized controlled trials, 4(four) case reports and 2(two) Retrospective report have been found. For types of treatment, 6(six) exercise therapies, 3(three) Korean medicine treatments and 7(seven) other treatments have been found. Main evaluation tools were VAS, ROM, NRS and Muscle strength. Conclusions : In this study, we analyzed the latest trend of studies on treatments of postoperative rotator cuff tear patients. Reviewing the international trends of studies on treatments for postoperative rotator cuff tear are essential for the future studies.

• Journal of Korean Society of Rural Planning
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• v.27 no.2
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• pp.35-42
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• 2021

This study was to analyze the Life-Cycle Physical Activity Therapy Programs (PATPs) in Hoseo Region and to suggest the Activation of the program. The subjects were the 81 PATPs performed in 36 of the Community Health Centers in the region. The basic data was collected by Official Documents, the Homepage of the Centers, Telephone Interview, and e-mail with the person in charge of the programs. All the data were classified to the administrative districts (Rural, Urban-Rural Intergration and Urban Region), the Life Cycles (Children, Youth, Adult and Old Adult) and the Health-related Fitness Variables (Strength/Muscle endurance, Flexibility and Aerobics). The ACSM's (American College Sports Medicine) Guidelines for Exercise Testing and Prescription were used to evaluate the PATPs. In the results, the number of the PATPs was too low compared to the population. Also, the PATPs were not considered to the Life-Cycle proportion of the population. The management of the PATPs was principally inadequate. The frequency and duration of the PATPs were deficient in order to improve the Health-related Fitness. In conclusion, the number of the PATPs should be increased proportionally compared to the population, operated and developed on the Specificity of the Life-Cycle Population in the administrative districts. Further, the PATPs should be managed on the scientific knowledge of physical activity therapy.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.16 no.2
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• pp.76-81
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• 2010

Purpose: This study examined how the degrees of muscle activity of Rectus Femoris and Tibialis Anterior during the four phases of walking vary according to three different treadmill slopes of $0^0$, $7^0$, and $15^0$. Methods: Subjects were 14 randomly selected healthy students attending G University in Seoul, Korea who had never had articular problems with lower limb and had no difficulties walking at the time of study. Results: 1) With respect to Rectus Femoris, in every phase of both forward and backward walking, there were significant differences among all of the slope degrees (p <.05), while the activity increased with increased slope degrees in every phase of backward walking. 2) For Tibialis Anterior, only in P2 and P3 of both forward and backward walking there were significant differences in every slope (p <.05). Conclusion: Both Rectus Femoris and Tibialis Anterior were found to be more active during backward walking compared to backward walking. In addition, the activity degree of Rectus Femoris was high between the early part of two foot support phase and the early part of one foot support phase, whereas that of Tibialis Anterior was high between the early part of one foot support phase and the latter part of both foot support phase.

• Physical Therapy Korea
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• v.2 no.1
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• pp.44-50
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• 1995

The purpose of this study was to investigate which of 4 positions produced the highest action potential in the rectus femoris muscle of normal adult subjects. Testing was performed in supine with the right leg performing a simple straight leg raise with the knee fully extended. The left leg, however, was placed in 4 different positions: 1. Full support with $0^{\circ}$ flexion. 2. Flexed on the plinth with $60^{\circ}$ knee flexion and foot flat. 3. Same as N0.2 but with $90^{\circ}$ knee flexion. 4. Left leg hanging over the end of the plinth with $90^{\circ}$ knee flexion, $0^{\circ}$ hip flexion and no foot support. This study was designed to compare the level of electromyographic activity of the rectus femoris under 4 positions. Fourty-three healthy young adults performed three trials of each exercise condition in random order in the supine position. Electromyographic activity was recorded from surface electrodes. Rectus femoris action potentials in all 4 positions were significantly different. The highest action potential at the end of movement of the right leg occurred with the left leg hanging over the end of the plinth with $90^{\circ}$ knee flexion. It is therefore recommended the straight leg raising be performed with the contralateral leg flexed at $90^{\circ}$ over the end of the supporting surface to obtain a maximum rectus femoris isometric contraction.

• Physical Therapy Korea
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• v.19 no.1
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• pp.19-27
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• 2012

The purpose of this study was to determine the effect of contralateral hip adduction (CHA) on thickness of lumbar stabilizers during hip abduction in side-lying. Twenty healthy subjects without back pain were recruited for this study. The thickness of transverse abdominis (TrA), internal oblique (IO) and quadratus lumborum (QL) were measured by ultrasonography. Pelvic lateral tilting motion was measured using a three-dimensional motion analysis system. Measurements were performed at rest position (RP), $35^{\circ}$preferred hip abduction (PHA) and $35^{\circ}$abduction with $10^{\circ}$contralateral hip adduction (CHA) in side-lying at the end of expiration. During the measurements, subjects were asked to maintain steady trunk alignment without hand support. Thickness of TrA and IO was significantly greater in CHA than in PHA and RP conditions. There was no significant difference in thickness of TrA and IO between PHA and RP conditions. Medio-lateral (M-L) thickness of QL was not significant between PHA and CHA conditions. Anterio-posterior (A-P) thickness of QL in PHA and CHA significantly decreased compared to RP condition. Angle of pelvic lateral tilting was significantly decreased in CHA compared to PHA condition. In conclusion, CHA can be recommended for increasing trunk stability without compensatory pelvic motion during hip abduction exercise in side-lying.

• Food Science of Animal Resources
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• v.32 no.5
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• pp.584-590
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• 2012

This study evaluated the effects of carnosine supplementation on carnosine concentration in muscles and blood biochemical indices of rats. Thirty-two eight-week-old Sprague-Dawley male rats were randomly divided into a control group (CON) as well as three carnosine-treated groups. The carnosine-treated groups included groups fed diets composed of 0.01% carnosine (LC), 0.1% carnosine (MC), and 1.0% carnosine (HC). Body weight gain, food intake, feed efficacy rate, protein efficacy rate, and organ weights were not significantly different among the groups. In all groups, the mean carnosine levels in gastrocnemius muscles were higher than the mean carnosine levels in soleus muscles. Carnosine concentrations in soleus muscles and gastrocnemius muscles were significantly higher in the HC group compared to all other groups (p<0.05). Serum triglyceride and LDL-cholesterol concentrations in all of the carnosine-supplemented groups were significantly lower than those of the control group (p<0.05), while HDL-cholesterol levels were significantly higher than those of the control group (p<0.05). Aspartate aminotransferase levels in rats supplemented with carnosine were significantly higher than those of the control group. In conclusion, diets supplemented with high levels of carnosine can increase carnosine concentrations in skeletal muscles, which might contribute to increased exercise capacity. Furthermore, these findings suggest that high levels of dietary carnosine improve the lipid profile of rats by lowering blood LDL-cholesterol and increasing HDL-cholesterol levels.