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Antioxidant and Anti-Obesity Effect of SM17 in High-Fat Diet Induced C57BL/6 Mice (고지방식이로 비만을 유도한 C57BL/6 마우스에서 SM17의 항산화 및 항비만 효과)

  • Kim, Soo Hyun;Kim, Su Ji;Kim, Kyeong Jo;Lee, Ah Reum;Roh, Seong-Soo;Lee, Young Cheol
    • The Korea Journal of Herbology
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    • v.32 no.5
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    • pp.47-55
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    • 2017
  • Objectives : Obesity is caused by the excess accumulation of fat in the body due to energy imbalance, and it causes various diseases. The aim of this study was to investigate an anti-obesity efficacy and an antioxidant activity of water from herbal mixture extract (SM17). Methods : The antioxidant activities were evaluated through radical scavenging assays using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radicals. To evaluated anti-obesity effect of SM17, we used a high fat diet fed mouse model. The SM17 (150 mg/kg body weight/day, p.o.) was treated every day for 6 weeks to C57BL/6 mice. Body weight and food intake were measured every day. The changes of reactive oxygen species (ROS), alanine aminotransferanse (ALT), aspartate aminotransferase (AST), triglycerids (TG) and total cholesterol (TC) in serum were analyzed after experiment. Also, expression of lipid metabolism related proteins were investigated by western blot analysis. Results : It was effective in antioxidant measurements, SM17 administration inhibited the biomarkers of lipid metaboism in serum and tissues. The administration of SM17 showed a significant reduction of body and tissue weight. Morever, it decreased ROS, ALT, AST, TG and TC in serum, compared with those of the obese mice. Adipogenesis-related protein expressions increased in obese mice compared to normal mice. However, SM17 group exhibited the down-expression of these proteins. Conclusion : A SM17 aqueous extract has a great effect on the stimulation (AMPK) activation, and may have a benefit to reduce a fatty acid metabolism through inhibition of lipid accumulation.

A Study on the Investment Efficiency of CB(Convertible Bond) (CB(전환사채)의 투자효율성에 관한 실증연구)

  • Sun-Je Kim
    • Journal of Service Research and Studies
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    • v.10 no.4
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    • pp.71-88
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    • 2020
  • CB(Convertible bond) is mezzanine security that have the characteristics of bonds and stocks. From the perspective of investors, the purpose of the research is to empirically investigate the degree of investment efficiency of CB and to suggest efficient investment plans. The research method investigated the maturity interest rate, conversion price, and conversion date for CB, and then linked it with daily stock price fluctuations after the conversion date to determine the degree of investment efficiency and stock conversion effect of CB. As a result of the study, it was analyzed that the ratio of the conversion price exceeded days was only about 1/4 of the conversion date, so the investment efficiency was low. The conversion day yield was -6.3% on average and the maturity day yield was -5.2% on average, showing a minus return on average, which was calculated differently from investor expectations. It was analyzed that the number of stocks with a minus conversion day is 2.4 times greater than the number of plus stocks and 3.7 times more than the number of plus stocks with a minus maturity return, so the expected return on stock conversion of CB is low. The research contribution was derived from the problem that the expected rate of return of CB is not high, and it is that the investor's point of view when purchasing CB was established.

Health Risk Assessment by Exposure to Heavy Metals in PM2.5 in Ulsan Industrial Complex Area (울산 산단지역 PM2.5 중 중금속 노출에 의한 건강위해성평가)

  • Ji-Yun Jung;Hye-Won Lee;Si-Hyun Park;Jeong-Il Lee;Dan-Ki Yoon;Cheol-Min Lee
    • Journal of Environmental Health Sciences
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    • v.49 no.2
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    • pp.108-117
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    • 2023
  • Background: When particles are absorbed into the human body, they penetrate deep into the lungs and interact with the tissues of the body. Heavy metals in PM2.5 can cause various diseases. The main source of PM2.5 emissions in South Korea's atmosphere has been surveyed to be places of business. Objectives: The concentration of heavy metals in PM2.5 near the Ulsan Industrial Complex was measured and a health risk assessment was performed for residents near the industrial complex for exposure to heavy metals in PM2.5. Methods: Concentrations of heavy metals in PM2.5 were measured at four measurement sites (Ulsan, Mipo, Onsan, Maegok) near the industrial complexes. Heavy metals were analyzed according to the Air Pollution Monitoring Network Installation and Operation Guidelines presented by the National Institute of Environmental Research. Among them, only five substances (Mn, Ni, As, Cd, Cr6+) were targeted. The risk assessment was conducted on inhalation exposure for five age groups, and the excess cancer risk and hazard quotient were calculated. Results: In the risk assessment of exposure to heavy metals in PM2.5, As, Cd, and Cr6+ exceeded the risk tolerance standard of 10-6 for carcinogenic hazards. The highest hazard levels were observed in Onsan and Mipo industrial complexes. In the case of non-carcinogenic hazards, Mn was identified as exceeding the hazard tolerance of 1, and it showed the highest hazard in the Ulsan Industrial Complex. Conclusions: This study presented a detailed health risk from exposure to heavy metals in PM2.5 by industrial complexes located in Ulsan among five age groups. It is expected to be utilized as the basis for preparing damage control and industrial emission reduction measures against PM2.5 exposure at the Ulsan Industrial Complex.

A Comparative Study of the Efficiency among Korea, Chinese, and Japanese Ports (한·중·일 항만효율성 비교연구)

  • KOO, Jong-soon;LEE, Jung-sun;JEON, Dong-hwa
    • The Journal of shipping and logistics
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    • v.27 no.3
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    • pp.457-474
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    • 2011
  • The aim of this study is to analyze the efficiency of major ports in Northeast Asia such as Korea, China and Japan. For the empirical analysis, we tried to apply the data envelopment analysis (DEA), which is an efficiency evaluation model based on mathematical programming theory, and we also established a model to Northeast Asian ports. In our opinion, DEA analysis which involves multiple inputs as well as multiple outputs in its efficiency valuation makes analysis more suitable for port efficiency measurement because ports produce a number of different outputs. In this paper, we attempted to analyze the relative efficiency of 27 ports (5 Korean ports, 13 Chinese ports, 9 Japanese ports) through DEA-CCR, DEA-BCC models. According to the result, Chinese ports are relatively efficient than Korean and Japanese ports. The result of the analysis shows that 7 Chinese ports are efficient in DEA-CCR model in 2009, but in DEA-BCC model 8 Chinese ports and 1 Koran port are efficient. Most of inefficient ports have a value closed to 1 in efficiency for scale, it means that the reason of inefficiency is caused from the technical aspect. Furthermore, we also verified that there exists excess of input in Korean and Japanese ports than Chinese ports.

Effects of insufficient dietary amino acids on the milk production of dairy cows milked three times daily (사료 내 아미노산의 부족이 하루 착유횟수를 2회에서 3회로 증가시킨 젖소의 유생산 반응에 미치는 영향)

  • Yeo, J.M.;Lee, S.H.;Lee, J.H.;Nho, W.G.;Kim, W.Y.
    • Journal of Practical Agriculture & Fisheries Research
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    • v.8 no.1
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    • pp.43-51
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    • 2006
  • An experiment was conducted to examine how the response of dairy cows to a change from twice to thrice-daily milking is affected by deficiencies in the dietary supplies of three amino acids, His, Met and Lys. The amino acid deficiencies were obtained by feeding the cows a diet of grass silage and a cereal-based supplement containing feather meal as the sole protein supplement. Taken overall, the results show that when cows were given the feather meal diet, even though dietary ME was in considerable excess, a deficiency of specific amino acids prevented any increase in milk yield in response to increasing the frequency of milking from twice to thrice daily. The results of half-udder milking showed that when cows consumed the diet deficient in amino acids, milking one half of the gland more frequently reduced the secretion of protein and lactose by the control gland. Neither MBF nor the ratio of 3-MH/creatinine in urine was affected by thrice-daily milking. The present results go a stage further in showing that, against a background of insufficient dietary amino acids, the stimulus of thrice-daily milking is not sufficient to induce a measurable change in the partition of amino acid use between body and udder.

Reduction of Nitrate-Nitrogen by Zero-valent Iron Nanoparticles Deposited on Aluminum yin Electrophoretic Method (전기영동법으로 알루미늄에 침적된 영가 철 나노입자에 의한 질산성 질소의 환원)

  • Ryoo, Won
    • Clean Technology
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    • v.15 no.3
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    • pp.194-201
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    • 2009
  • Reductive reactivity of zero-valent iron nanoparticles was investigated for removal of nitrate-nitrogen which is considered one of the major water pollutants. To elucidate the difference in reactivity between preparation methods, iron nanoparticles were synthesized respectively from microemulsion and aqueous solution of ferric ions. Iron nanoparticles prepared from microemulsion were deposited on aluminum by electrophoretic method, and their reaction kinetics was compared to that of the same nanoparticles suspended in aqueous batch reaction. With an approximation of pseudo-first-order reaction, rate constants for suspended nanoparticles prepared from microemulsion and dilute aqueous solution were $3.49{\times}10^{-2}min^{-1}$ and $1.40{\times}10^{-2}min^{-1}$, respectively. Iron nanoparticles supported on aluminum showed ca. 30% less reaction rate in comparison with the identical nanoparticles in suspended state. However, supported nanoparticles showed the superior effectiveness in terms of nitrate-nitrogen removal per zero-valent iron input especially when excess amounts of nitrates were present. Iron nanoparticles deposited on aluminum maintained reductive reactivity for more than 3 hours, and produced nitrogen gas as a final reduction product of nitrate-nitrogen.

Synthesis of High-purity Silicon Carbide Powder using the Silicon Wafer Sludge (실리콘 기판 슬러지로부터 고순도 탄화규소 분말 합성)

  • Hanjung Kwon;Minhee Kim;Jihwan Yoon
    • Resources Recycling
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    • v.31 no.6
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    • pp.60-65
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    • 2022
  • This study presents the carburization process for recycling sludge, which was formed during silicon wafer machining. The sludge used in the carburization process is a mixture of silicon and silicon carbide (SiC) with iron as an impurity, which originates from the machine. Additionally, the sludge contains cutting oil, a fluid with high viscosity. Therefore, the sludge was dried before carburization to remove organic matter. The dried sludge was washed by acid cleaning to remove the iron impurity and subsequently carburized by heat treatment under vacuum to form the SiC powder. The ratio of silicon to SiC in the sludge was varied depending on the sources and thus carbon content was adjusted by the ratio. With increasing SiC content, the carbon content required for SiC formation increased. It was demonstrated that substoichiometric SiCx (x<1) was easily formed when the carbon content was insufficient. Therefore, excess carbon is required to obtain a pure SiC phase. Moreover, size reduction by high-energy milling had a beneficial effect on the suppression of SiCx, forming the pure SiC phase.

Yield Formations of Sesame(Sesamum indicum L.) as Affected by Different Conditions of Soil Drainage (토양의 배수조건 차이가 참깨 수량성에 미치는 영향)

  • Choi, H.K.;Goo, J.O.;Kim, Y.Z.;Lee, D.G.
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.27 no.3
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    • pp.276-282
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    • 1982
  • To estimate the responses of sesame plant in growth and yielding traits to different soil drainage conditions, a pot trial was conducted by using of sesame variety "Suweon-9" were introduced with 5 different mixing combinations of clay and sea-sand soils as 0:100, 25:75, 50:50, 75:25, and 100:0 percents in volumetric ratio. Also two irrigation methods as 20mm/6 days interval and 10mm/3 days interval were detected. As a result, water drainage was linearly decreased with increament of clay contents. And the excess drainage condition(such as pure sand soil) required more irrigation, however in crop growths, no significant differences among various soil drainage conditions except the pure sand were recognized. On the other hand, number of capsules per plant, among other yielding components, was most contributed factor to the yield, which was effectively given from the soil mixed with clay and sea-sand as 75% and 25%, respectively. Therefore, much similar responses were also detected from the seed yields per a sesame plant. However, the number of seeds per capsule and maturity function were more effectively composed under the soil mixed with clay and sea-sand as 25% and 75% respectively better than under the soil of 75% and 25%. As a conclusion, the yielding responses of sesame plant was advanced more effectively at the soil conditions of water conserved type (e.g. 25%/75% in clay/sand ratio) than of water-draining type (e.g. 75%/25% in clay/sand ratio).nd ratio).

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Methods of Estimating Growing Degree Days to Predict Growth Duration in Maize (옥수수의 생육기간 예측을 위한 Growing Degree Days의 계산방법)

  • Jong, Seung-Keun;Lee, Suk-Soon;Park, Keun-Yong
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.31 no.2
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    • pp.186-194
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    • 1986
  • In an attempt to find better ways to relate growth with temperature and to estimate maturity differences in corn (Zea mays L.), various formulas of computing Growing Degree Days (GDD) were evaluated. Utilizing data from 17 plantings of a single cross, Suweon 19, over a 3 year period, 24 different methods of computing GDD were compared for their ability to reduce variations over different plantings. The best equation was to compute GDD with a base temperature of 10$^{\circ}C$ and an optimum of 30$^{\circ}C$. The excess temperature above 30$^{\circ}C$ was subtracted to account for high temperature stress. GDDs required for emergence and silking of Suweon 19 were 64${\pm}$12$^{\circ}$ and 794${\pm}$19$^{\circ}$, respectively. Based on these GDD values, emergence and silking dates could be estimated with a variation less than 3 days. The observed and estimated number of days from planting to emergence and silking were not significantly different.

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Evaluation of Dynamic Group Pile Effect in Sand by 1 g Shaking Table Tests (1g 진동대 실험을 이용한 사질토 지반에서의 동적 군말뚝 효과 분석)

  • Yang, Eui-Kyu;Choi, Jung-In;Han, Jin-Tae;Kim, Myoung-Mo
    • Journal of the Korean Geotechnical Society
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    • v.26 no.8
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    • pp.77-88
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    • 2010
  • In this study, 1 g shaking table group pile tests were performed for various conditions of subgrade and pile spacing. The pile spacing was changed from three to seven times of pile diameters. It could be confirmed that the dynamic p-y curves for the group pile observed as the results of a series of shaking table tests show difference according to the pile spacing, the pile location within the pile group, the relative density of subgrade and the excess pore pressure during earthquake. The dynamic p-multipliers were calculated by comparing the dynamic p-y backbone curves of a single pile suggested by Yang (2009) and dynamic p-y curves for the group pile. Dynamic p-multiplier values overall increase as the relative density of subgrade and amplitude of input acceleration increase. The dynamic group pile effect was neglected, if the pile spacing was seven times as large as pile diameters. It was found that the exisiting p-multiplier values suggested by various researchers for the static and dynamic loading, and the values recommended by globally used specifications show difference with the test results by up to 0.7 (approximately 70%). Therefore, the dynamic p-multipliers were newly suggested according to the pile spacing and the relative density of subgrade using the test results.