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Effect of Cosurfactant on Microemulsion Phase Behavior in NP7 Surfactant System (보조계면활성제가 NP7 계면활성제 시스템의 마이크로에멀젼 형성에 미치는 영향에 관한 연구)

  • Lim, HeungKyoon;Lee, Seul;Mo, DaHee;Lim, JongChoo
    • Applied Chemistry for Engineering
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    • v.22 no.4
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    • pp.416-422
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    • 2011
  • In this study, the effect of cosurfactant on the phase equilibrium and dynamic behavior was studied in systems containing NP7 nonionic surfactant solutions and nonpolar hydrocarbon oils. All cosurfactants used during this study such as n-pentanol, n-octanol and n-decanol acted as a hydrophobic additive and thus promoted the transition from an oil in water (O/W) microemulsion (${\mu}E$) in equilibrium with an excess oil phase to a three-phase region containing excess water, excess oil, and a middle-phase microemulsion and further to a water in oil (W/O) ${\mu}E$ in equilibrium with the excess water phase. The transition temperature was found to decrease with both increases in the chain length and amount of addition of a cosurfactant. Dynamic behavior studies under O/W ${\mu}E$ conditions showed that an oil drop size decreased with time due to the solubilization into micelles. On the other hand, both the spontaneous emulsification of water into the oil phase and the expansion of oil drop were observed under W/O ${\mu}E$ conditions because of the diffusion of surfactant and water into the oil phase. Under conditions of a three-phase region including a middle-phase ${\mu}E$, both the rapid solubilization and emulsification of the oil into aqueous solutions were found mainly due to the existence of ultra-low interfacial tension. Dynamic interfacial tension measurements have been found to be in a good agreement with dynamic behavior results.

Cold-Heat and Excess-Deficiency Pattern Identification Based on Questionnaire, Pulse, and Tongue in Cancer Patients: A Feasibility Study (암 환자 대상 설문지, 맥진기, 설진기 결과를 활용한 한열허실변증에 대한 예비 연구)

  • Choi, Yujin;Kim, Soo-Dam;Kwon, Ojin;Park, Hyo-Ju;Kim, JiHye;Choi, Woosu;Ko, Myung-Hyun;Ha, Su-Jeung;Song, Si-Yeon;Park, So-Jung;Yoo, Hwa-Seung;Jeong, Mi-Kyung
    • The Journal of Korean Medicine
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    • v.42 no.1
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    • pp.1-11
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    • 2021
  • Objectives: This pilot study aimed to evaluate the agreement between traditional face-to-face Korean medicine (KM) pattern identification and non-face-to-face KM pattern identification using the data from related questionnaires, tongue image, and pulse features in patients with cancer. Methods: From January to June 2020, 16 participants with a cancer diagnosis were recruited at the one Korean medicine hospital. Three experienced Korean medicine doctors independently diagnosed the participants whether they belong to the cold pattern or not, heat pattern or not, deficiency pattern or not, and excess pattern or not. Another researcher collected KM pattern related data using questionnaires including Cold-Heat Pattern Identification (CHPI), tongue image analysis system, and pulse analyzer. Collected KM pattern related data without participants' identifier was provided for the three Korean medicine doctors in random order, and non-face-to-face KM pattern identification was carried out. The kappa value between face-to-face and non-face-to-face pattern identification was calculated. Results: From the face-to-face pattern identification, there were 13/3 cold/non-cold pattern, 4/12 heat/non-heat pattern, 14/2 deficiency/non-deficiency pattern, and 0/16 excess/non-excess pattern participants. In cold/non-cold pattern, kappa value was 0.455 (sensitivity: 0.85, specificity: 0.67, accuracy: 0.81). In heat/non-heat pattern, the kappa value was 0.429 (sensitivity: 0.75, specificity: 0.72, accuracy: 0.75). The kappa value of deficiency/non-deficiency and excess/non-excess pattern was not calculated because of the few participants of non-deficiency, and excess pattern. Conclusions: The agreement between traditional face-to-face pattern identification and non-face-to-face pattern identification seems to be moderate. The non-face-to-face pattern identification using questionnaires, tongue, and pulse features may feasible for the large clinical study.

Study on Mechanistic Pattern Identification of Disease for Uterine, Urine and Excrements Parts of DongEuiBoGam NaeGyungPyen ("동의보감(東醫寶鑑)" "내경편(內景篇)"의 포(胞), 소변(小便), 대편(大便)에 나타난 질병(疾病)의 변증화(辨證化) 연구)

  • Kim, Yeong-Mok
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.5
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    • pp.727-736
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    • 2010
  • This study is about researching mechanistic pattern identification of disease for DongEuiBoGam NaeGyungPyen by analysing with pattern identification of modern Traditional Korean medical patholgy as more logical, systematic and standardized theory. Disease pattern mechanisms of uterine, urine and excrements parts of DongEuiBoGam NaeGyun gPyen in NaeGyungPyen of DongEuiBoGam are these. Menstrual irregularities in DongEuiBoGam can be classified flui d-humor depletion, blood deficiency, qi deficiency, qi stagnation, qi stagnation complicated by heat, blood stasis, blood deficiency complicated by heat, syndrome of heat entering blood chamber, syndrome of cold entering blood chamber. The disease pattern of abdominal pain after menstruation in DongEuiBoGam is blood deficiency complicated by heat, and a dysmenorrhea represents blood stasis with heat, fluid-humor deficiency. Advanced menstruation represent dual heat of the qi and blood, delayed menstruation is blood deficiency. The disease pattern of inhibited urination in DongEuiBoGam can be classified deficiency heat pattern of kidney yin deficiency(yin deficiency with effulgent fire), kidney qi deficiency, yin deficiency with yang hyperactivity, fluid-humor depletion, spleen-stomach dual deficiency, and excess he at pattern of bladder excess heat. The disease pattern of urinary incontinence in DongEuiBoGam can be classified deficiency pattern of kidney-bladder qi deficiency, consumptive disease, lung qi deficiency, kidney yin deficiency(yin deficiency with effulgent fire), kidney yang deficiency and excess pattern of lower energizer blood amassment, bladder excess heat. And most of them are deficiency from deficiency-excess Pattern Identification. The disease pattern of diarrhea in DongEuiBoGam can be classified deficiency pattern of qi deficiency, qi fall, spleen yang deficiency, kidney yang deficiency and so on and excess pattern of wind-cold-summerheat-dampness-fire, phlegm-fluid retention, dietary irregularities, qi movement stagnation. And most of them are deficiency from deficiency-excess Pattern Identification. Like these, this study identify pattern of disease in DongEuiBoGam by mechanism of disease theory.

Development of Eyes Inspection Questionnaire(EIQ) and Regression Analysis between EIQ Items and deficiency or excess patterns of Eyes Inspection (안진(眼診) 설문지 개발 및 안진(眼診) 설문의 허실(虛實) 연관성 연구)

  • Seo, Jae-Ho;Choi, Jin-Yong;Oh, Whan-Sup;Park, Young-Bae;Park, Young-Jae
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.18 no.2
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    • pp.75-84
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    • 2014
  • Objectives Eyes, one of visual inspection regions, present important clues to pathological patterns including deficiency and excess patterns to the clinicians. The purpose of this study was to develop Eyes Inspection Questionnaire (EIQ) and to examine which items among the EIQ were more predictive of clinicians' determination for the deficiency and excess patterns. Methods Nine questionnaire items for Visual Inspection of Eyes were extracted through the literature review. These items were presented to the 4 Korean medical doctors who are specialized in visual inspection to conduct the Delphi method. The Korean medical doctors were asked to rate the importance of each items for the corresponding Visual Inspection of Eyes, using a Likert 5-point scale(the 3 points of importance as a cut-off point). Then, out of 75 photographs submitted to the Society of HyungSang Medicine in 2009, 30 portrait pictures were selected as samples. The samples were copied to make 60 sample pictures, and then randomly assigned to 4 clinicians. The 4 clinicians evaluated the 60 samples for excess and deficiency of the eyes and were asked to check the 6 questionnaire items. The results were recorded as 5-points-scale, and their average and standard deviations were calculated. Intra- class reliability test and multi regression test were performed using SPSS 13. Results Intra-class correlation coefficient (ICC) was between 0.750 to 0.841 (P<0.05). Indices for visual inspection of the eyes were: endowment of the bone structure around the eyes; brightness of the eyes; upward deviation of the eyes; eye shapes; and definition of iris. 76.92% of deficiency symptom patterns and 86.42% of the excess symptom patterns matched the patterns predicted by the visual inspection of the eyes, according to the frequency analysis. According to the multiple regression analysis, were significantly related to the excessive symptoms, and to the deficiency symptoms. Conclusion This study is the first attempt of development for checklist of excess and deficiency of Visual Inspection of Eyes and quantitative measurement of excess and deficiency using the Visual Inspection of Eyes by the visual inspection experts. Still, additional studies are needed regarding the relationship visual inspection methods have with existing standards of diagnosis.

Excess Flow Valves for Underground Gas Pipeline and their Performance Testing Equipment Development (연료가스 매몰배관용 과류차단밸브와 성능시험 장치 개발)

  • Lee, Ugwiyeon;Joo, Yukyung;Lee, Jinhan
    • Journal of the Korean Institute of Gas
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    • v.22 no.4
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    • pp.74-81
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    • 2018
  • The Korean Government has proceeded petroleum gas pipeline construction business since 2014 for rural districts. The operating pressure of petroleum gas pipeline are from 25kPa to 75kPa which are different from that of natural gas pipeline. Petroleum gas pipeline pressure is ten or forty times higher than natural gas operating pressure. For this reason, petroleum gas pipeline has higher probability of accident occurrence from massive gas leakage. Korea Gas Safety Corporation begins to development excess flow valves and their performance testing equipment since 2017. The excess flow valves stop the gas flow when a overflow happened in gas pipeline. The excess flow valves are generally not installed in main pipeline, because that may block massive gas supply. So, the valves are installed in starting points of branch pipes. According to the number of house and amount of gas use, a shut-off point of exxcess flow valve is determined called as Trip Flow. The trip point is the most important thing of excess flow valve, so, it is required a equipment testing the performances of excess flow valve as trip point.

Nitrogen-15 Determination in Tissues of Laying Hens Fed on Different Levels of $^{15}N-Chlorocholine$ Chloride ($^{15}N-CCC$) Diets

  • Nurhayati, Nurhayati;Thinggaard, Grete;Chakeredza, S.;Reineking, A.;Langel, R.;ter Meulen, U.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.3
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    • pp.412-417
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    • 2007
  • An experiment was conducted to determine the distribution of nitrogen-15 in tissues of laying hens receiving different levels of $^{15}N$-CCC in diets. Twenty brown laying hens were divided into four groups and randomly assigned into one of four dietary treatment groups consisting of 0, 5, 50 and 100 ppm $^{15}N$-CCC inclusion. The hens were individually fed with the $^{15}N$-CCC diets in battery cages for 11 days and then all hens restored to feeding on the control diet for 7 days. After eleven days, eight hens were slaughtered, and the others were slaughtered seven days after $^{15}N$-CCC diets withdrawal. Samples of blood, liver, heart and meat were collected and their $^{15}N$ contents were determined. The ${\delta}^{15}N$ excess (${\delta}^{15}N$-ex) and atom percentage excess in $^{15}N$ were calculated. The ${\delta}^{15}N$-ex and atom percentage excess $^{15}N$ increased significantly (p<0.05) with increasing levels of $^{15}N$-CCC in diets in all tissues after feeding $^{15}N$-CCC diets for eleven days. The highest concentration of ${\delta}^{15}N$-ex and atom percentage excess $^{15}N$ were detected in blood, followed in order by liver, heart and thigh meat. The concentrations reduced significantly (p<0.05) after $^{15}N$-CCC diets were withdrawn. Comparison between treatment groups showed that ${\delta}^{15}N$-ex and atom percentage excess $^{15}N$ were still higher in hens that had been fed diets with higher levels of $^{15}N$-CCC. This study showed that nitrogen-15 was distributed in blood, liver, heart and meat of laying hens.

Effect of Microbubble Ozonation Process on Performance of Biological Reactor System for Excess Sludge Solubilisation (마이크로버블오존을 이용한 잉여슬러지 가용화 처리가 생물반응조의 성능에 미치는 영향)

  • Lee, Shun-Hwa;Jung, Kye-Ju;Kwon, Jin-Ha;Lee, Se-Han
    • Journal of Korean Society of Environmental Engineers
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    • v.33 no.2
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    • pp.113-119
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    • 2011
  • The study purpose was to examine an effect of zero emission of excess sludge on biological reactor and treated water quality within the biological reactor in the process of biological treatment combined with excess sludge reduction system with ozone. Under an ozone injection rate 0.03 g $O_3/g$ SS, Sludge Disintegration Number (SDN) 3 and less than pH 4 as pre-treatment process, it was possible to maintain a stable biological treatment process without sludge disintegration. In the test of $OUR_{max}$, of sludge, its value was hardly under the condition of ozone injection rate 0.03 g $O_3/g$ SS. There were almost no changes of MLVSS/MLSS within biological reactor followed by a solubilization of excess sludge. Accumulation of microorganism within biological reactor was also not observed. After solubilization of excess sludge, an increase for organic matter and SS concentrations of an effluent was not observed and T-N concentration was reduced by increasing nitrification and denitrification rate within biological reactor. Most of T-P was not removed by zero emission of excess sludge and was leaked by being included in effluents.

Study on the Relationship between Korean Standard of Pattern Identification (II) and Pattern Identification of Cold-Heat and Deficiency-Excess (한국형 중풍 변증 표준안 - II와 한열허실 변증지표의 연관성 연구)

  • Kim, So-Yeon;Lee, Jung-Sup;Oh, Dal-Seok;Kang, Byoung-Kab;Ko, Mi-Mi;Kim, Jeong-Cheol;Kwon, Se-Hyug;Bang, Ok-Sun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.1
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    • pp.15-21
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    • 2010
  • Previously standardization study for identifying 5 types of pattern identification of stroke patients has been performed and the Korean standard of pattern identification (II) was developed. In the present study we investigated the interactions between total indices designated by the Korean standard of pattern identification(KSPI II) and indices for PI of Cold-Heat and Deficiency-Excess. Indicators for Cold-Heat and Deficiency-Excess are isolated from 58 indices through the survey of oriental medicine doctors and their relationship with KSPI-II indices was analyzed by corresponding analysis method using data of 1581 stroke patients. Means and standard deviations indicated that 2 Cold indices, 14 Heat indices, 12 Deficiency indices, and 5 Excess indices were included for Cold-Heat and Deficiency-Excess pattern identification. The results of corresponding analysis shows the relationship of 57 indices and 4 types of pattern identification (excluding 1 index and 1 pattern among 58 indices and 5 patterns) using the cross-tabulation which was obtained from the clinical data. Most of Cold and Heat index were divided to dimension 1(inertia 51.9%) obtained from the result of corresponding analysis. Deficiency and Excess index were partially associated with dimension 2(inertia 31.7%). These data suggest that pattern identification of Cold-Heat plays an role in the standardization of pattern identification in stroke, although further studies are required by various trials such as analysis of surveys and clinical data.

Deformation Characteristics of Non-liquefied, Reconstituted, Weathered Residual Soils due to the Cyclic Loading (반복재하에 의한 미액상화 재성형 풍화토의 변형 특성)

  • Choi Yeon-Su;Yune Chan-Young;Jang Eui-Ryong;Chung Choong-Ki
    • Journal of the Korean Geotechnical Society
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    • v.22 no.6
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    • pp.41-49
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    • 2006
  • This paper deals with development and dissipation of excess pore pressure induced by the cyclic load. Cyclic triaxial tests on reconstituted samples of weathered residual soils, which were widely used as construction materials in Korea, were performed. Test results showed that excess pore pressures developed under undrained condition increased with the increase of cyclic loads and confining pressures. And a new concept based on modified excess pore pressure ratio (MEPPR) was proposed for simply estimating excess pore pressures in terms of the number of cyclic load, irrespective of cyclic loads and confining pressures. Also, it was proposed that excess pore pressure ratio (EPPR) could be effectively utilized to estimate volumetric strains during dissipation which decreased as confining pressures increased. Consequently, concept and method to effectively estimate settlements under non-liquefied condition, induced by dynamic loads such as earthquake loads were evaluated based on laboratory test results for reconstituted weathered residual soils.