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Cold-Heat and Excess-Deficiency Pattern Identification Based on Questionnaire, Pulse, and Tongue in Cancer Patients: A Feasibility Study

암 환자 대상 설문지, 맥진기, 설진기 결과를 활용한 한열허실변증에 대한 예비 연구

  • Choi, Yujin (Clinical Medicine Division, Korea Institute of Oriental Medicine) ;
  • Kim, Soo-Dam (East West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Kwon, Ojin (Clinical Medicine Division, Korea Institute of Oriental Medicine) ;
  • Park, Hyo-Ju (Clinical Medicine Division, Korea Institute of Oriental Medicine) ;
  • Kim, JiHye (Clinical Medicine Division, Korea Institute of Oriental Medicine) ;
  • Choi, Woosu (Future Medicine Division, Korea Institute of Oriental Medicine) ;
  • Ko, Myung-Hyun (East West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Ha, Su-Jeung (East West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Song, Si-Yeon (East West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Park, So-Jung (East West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Yoo, Hwa-Seung (East West Cancer Center, Seoul Korean Medicine Hospital of Daejeon University) ;
  • Jeong, Mi-Kyung (Clinical Medicine Division, Korea Institute of Oriental Medicine)
  • 최유진 (한국한의학연구원임상의학부) ;
  • 김수담 (대전대학교대전한방병원동서암센터) ;
  • 권오진 (한국한의학연구원임상의학부) ;
  • 박효주 (한국한의학연구원임상의학부) ;
  • 김지혜 (한국한의학연구원임상의학부) ;
  • 최우수 (한국한의학연구원미래의학부) ;
  • 고명현 (대전대학교대전한방병원동서암센터) ;
  • 하수정 (대전대학교대전한방병원동서암센터) ;
  • 송시연 (대전대학교대전한방병원동서암센터) ;
  • 박소정 (대전대학교대전한방병원동서암센터) ;
  • 유화승 (대전대학교서울한방병원동서암센터) ;
  • 정미경 (한국한의학연구원임상의학부)
  • Received : 2020.09.01
  • Accepted : 2020.11.12
  • Published : 2021.03.01

Abstract

Objectives: This pilot study aimed to evaluate the agreement between traditional face-to-face Korean medicine (KM) pattern identification and non-face-to-face KM pattern identification using the data from related questionnaires, tongue image, and pulse features in patients with cancer. Methods: From January to June 2020, 16 participants with a cancer diagnosis were recruited at the one Korean medicine hospital. Three experienced Korean medicine doctors independently diagnosed the participants whether they belong to the cold pattern or not, heat pattern or not, deficiency pattern or not, and excess pattern or not. Another researcher collected KM pattern related data using questionnaires including Cold-Heat Pattern Identification (CHPI), tongue image analysis system, and pulse analyzer. Collected KM pattern related data without participants' identifier was provided for the three Korean medicine doctors in random order, and non-face-to-face KM pattern identification was carried out. The kappa value between face-to-face and non-face-to-face pattern identification was calculated. Results: From the face-to-face pattern identification, there were 13/3 cold/non-cold pattern, 4/12 heat/non-heat pattern, 14/2 deficiency/non-deficiency pattern, and 0/16 excess/non-excess pattern participants. In cold/non-cold pattern, kappa value was 0.455 (sensitivity: 0.85, specificity: 0.67, accuracy: 0.81). In heat/non-heat pattern, the kappa value was 0.429 (sensitivity: 0.75, specificity: 0.72, accuracy: 0.75). The kappa value of deficiency/non-deficiency and excess/non-excess pattern was not calculated because of the few participants of non-deficiency, and excess pattern. Conclusions: The agreement between traditional face-to-face pattern identification and non-face-to-face pattern identification seems to be moderate. The non-face-to-face pattern identification using questionnaires, tongue, and pulse features may feasible for the large clinical study.

Keywords

Acknowledgement

This work was supported by grants from the Korea Institute of Oriental Medicine (KSN2013240) and Ministry of Health & Welfare, Republic of Korea (HI19C1046).

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