• Analytical Science and Technology
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• v.14 no.3
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• pp.221-229
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• 2001

The bioequivalence study of two tiropramide products was evaluated in 16 health male volunteers following intra-muscular injection. Test product was Tiram$^{(R)}$ injection (S Pharm. Co, Ltd.) and reference product was Tiropa$^{(R)}$ injection(D Pharm. Co., Ltd.). The drug concentration in plasma was determined by GC/MS for over a period of 8 hours after injection. Analysis of variance reveal that there are no differences in AUC (area under the plasma concentration-time curve from time zero to infinity), Cmax (maximum plasma concentration) and Tmax (time to reach Cmax). The differences of mean AUC, Cmax and Tmax between two products were 0.73, -1.385 and -12.994%, respectively. Minimum detectable differences (%) at ${\alpha}=0.05$ were all less than 20% given as a guideline (10.05, 17.90 and 19.01% for AUC, Cmax and Tmax, respectively). From these results, the two formulations of tiropramide are bioequivalent and thus, may be prescribed interchangeably.

• Analytical Science and Technology
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• v.13 no.5
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• pp.675-682
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• 2000

The concentration of dioxins from flue gases of municipal waste incineration facilities with capacities over 50 tons/day are regulated by the guideline: $0.1ng-TEQ/Nm^3$ for new facilities, and $0.5ng-TEQ/Nm^3$ for existing facilities and it will be strengthened to $0.1ng-TEQ/Nm^3$ until 2003 year. Dioxins from these incineration facilities have to be measured more than 2 times annually by the Official Test Facilities of Dioxins. Seven institutions have been certified so far as the Official Test Facilities of Dioxins. These facilities have to be evaluated by the quality control program provided by National Institute of Environmental Research every year. We reported the results of quality control test performed in 1999. Four institutions certified in 1998 sampled flue gases at stack of M incineration facilitiy and analyzed dioxins by Official Methods of Air Pollution. The isokinetic coefficients, the parameter for evaluation of sampling ability were excellent for all four institutions. They were 100.9%, 102.4%, 102.1% and 99.2%, respectively. The criteria required are as follows; resolution over 10,000, mass calibration within ${\pm}5ppm$, ion abundance ratio within 15%, and the recovery of 50-120%. As results, those institutions also met these parameters of Official Method of Air Pollution.

• Journal of the Korean association of regional geographers
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• v.9 no.1
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• pp.77-85
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• 2003

The purpose of this study is to critically evaluate the DPD development plan of Kyungpook province, which was established in 1996 and slightly revised in 1997 in terms of a theoretical framework, fair distribution and ecological sustainability, and the feasibility of capital supply of the proposed plan. The early part of the proposed plan introduces various theories and approaches developed in regional (or local) development planning as a general after the 1970s. However, the theories and approaches mentioned are not used as a guideline to establish the DPD development plan of Kyungpook province as a historically developed particular place. Most of the plans were tourism-oriented and did not seriously take the local characteristics into account. All the DPDs of Kyungpook province are located in the upper parts of the Nakdong River basin. So those regions are ecologically vulnerable. But a lot of problems remain concerning the environmental impacts of the proposed development plan. In terms of fair distribution and ecological sustainability, it seems that the DPD development plan was routinely made by a handful of professors and administrators, based on a standard format of regional (or local) development as a genera]. Finally, capital is the key factor for successfully implementing the DPD development plan. It came from the national and local government and private investors. The government have generally financed the construction of infrastructures, not profit-oriented projects such as tourism and resort businesses. However, the feasibility of private capital was not carefully examined in the plan.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.29 no.5
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• pp.260-268
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• 2017

In this study, wind characteristics of a shipping container were investigated through the wind tunnel test (high-frequency force balance test), and damage occurrence velocities of various containers with weights were evaluated based on results of the wind tunnel tests. As a result, mean wind force coefficients acting on containers in x-direction increased in the order of 12ft, 20ft, 40ft and 40ft high cube. On the other hand, mean wind force coefficients at y-direction increased in the order of 40ft high cube, 40ft, 20ft and 12ft. It was suggested that the shear layer separated from the corner of windward surface of the container is reattached on the sides of it, and then the mean wind force coefficient is weaker. As a result of the damage occurrence velocity on containers with weights, it was found that the probability of occurrence of sliding is higher rather than that of overturning. Further, the most unfavorable container was 40ft high cube, and the sliding and overturning occurrence velocities were 20.4 m/s and 26.8 m/s, respectively. Furthermore, the regression formula for sliding and overturing occurrence velocitys were proposed based on the results of relationship between weights of containers and damage occurrence velocities. These results are expected to be useful in establishing a guideline for external force estimation acting on container securing equipment and stacking way.

• Korean Journal of Environmental Biology
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• v.32 no.4
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• pp.271-285
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• 2014

Aluminum flows into the river from the abandoned mine leachate, industrial wastewater, and sewage and is responsible for acute toxicity in aquatic organisms. Recently, the number of reports have indicated the increased toxicity in a variety of aquatic organisms' due to the aluminum toxicity. In this study, we reviewed the toxicity of aluminum on aquatic invertebrates, fishes and amphibians and suggested the guideline for management of aluminum residues in aquatic environment and strategies for aluminum toxicity evaluation. In aquatic animals aluminum complexes evoke gill dysfunction primarily, the cytotoxicity, genotoxicity, oxidative stress, disruption of endocrine function, reproductive success, metabolism and homeostasis. Notably, at environmentally relevant concentration, aluminum complex can alter the hormone levels in fish in acidic condition. Further, since the solubility of aluminum is higher in the acidic and basic conditions, thus it is likely that the toxic effects of aluminum may not only occur in acidic water near the abandoned mines but also in lakes and rivers, where pH is raised by algal bloom.

• Journal of Engineering Education Research
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• v.10 no.1
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• pp.77-85
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• 2007

Though accreditation demands considerable ongoing effort on the part of the college, about 10 percent of Korean engineering colleges has been accredited for 5years by ABEEK. It is true that engineering accreditation contributed the Korean engineering education to improve. Many engineering colleges which had prepared the engineering accreditation developed the integrating system for the engineering education, and over 50 engineering education research centers which assisted to programs in accreditation were founded. Also the faculty commitment to quality programs and excellence in teaching, continuous counseling for students, portfolio guiding and continuous quality improvement(CQI) etc. were performed for accreditation preparation. The engineering colleges preparing accreditation has made efforts for satisfying accreditation criteria, but it is difficult of modifying education systems which have been maintained by now. In addition, engineering colleges need guideline how to satisfy standards. The purpose of this study is to analyze draft statement of 4 universities which were evaluated in 2006 and to suggest the minimal resources for engineering colleges to prepare accreditation.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2008.11a
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• pp.170-175
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• 2008

The research team for the virtual construction development was established with the support of Korea Ministry of Construction and Transportation, and KICTEP (Korea Institute of Construction and Transportation Technology Evaluation and Planning). Its aims are to develop system that is to improve productivity & quality, to create a higher value-added business, and to cultivate international competitiveness in the construction industry. The virtual construction system is a design, engineering, and construction management information system that allows the project participants to effectively share the information throughout the construction life cycle with the support of 3D and design information. To achieve this, the research team focuses on developing several systems. First, the team focuses on developing for the pre-planning, the structural engineering, MEP, and the 3D based estimation system. Second, they focus on developing a simulation system for the construction process planning and feasibility study with help of the virtual reality technologies. Third, they focus on developing the CPLM (Construction Project Life-cycle Management) system for managing construction project data, and the decision support system that makes the collaboration among the project participants based on 3D technologies and information. We also focus on developing the SDAI (Standard Data Access Interface), the localized guideline for 3D design, and a training program. In addition, we focus on developing the undeveloped area of the commercial system and building an environment that can support the communication and collaboration in the construction life-cycle rather than developing the existing and commercialized system.

• Journal of Conservation Science
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• v.28 no.1
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• pp.53-62
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• 2012

The archival objects are tangible evidence related to the public service. They are unique and offer information representing the specific events, time or person. The archival objects as modern cultural heritage do not have the guideline to classify, manage and conserve them. Especially, it is difficult to apply general conservation process for burial artifacts, because there are few study example of conservation for metal archival objects and they have complex administrative value. We tried to find suitable material and application method for consolidation of copper alloy archival object. We choose three kinds of wax and acrylic resin for burial artifacts and had done comparative analysis of their characterizations following kinds and coating methods. As a result of evaluation by several surface analysis such as optical microscope, measuring film thickness, adhesive strength, contact angle and yellowing test, acrylic resin can use to archival objects of copper alloy, effectively but the method of heating after dip-coating with Wax B used before can get best effect of consolidation.

• Journal of Korean Society of Environmental Engineers
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• v.37 no.5
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• pp.277-284
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• 2015

In order to analyze the contamination level of sediment samples taken from Chusori and Chudong areas in Daechung Reservoir, the particle size and concentrations of organics and nutrients were analyzed and phosphorus fractionation analysis was conducted. The average fraction of silt-sized particles was 92% in the sediments taken from Chudong area and Chusori area at the site adjacent to main current, which was higher than that from the upper Chusori area. The concentrations of total phosphorus in the sediments at Chusori and Chudong area were 999 (${\pm}98$) and 1,123 (${\pm}119$) mg/kg sediment, respectively. The fractions of autochthonous phosphorus, which can be readily eluted by change of environmental conditions, were much higher than those of allochthonous phosphorus, indicating the internal load can contribute the eutrophication in these areas. The concentrations of total nitrogen were over 5,600 mg/kg sediment in all samples, which is the guideline of Contamination Assessment of River and Lake Sediments of the Ministry of Environment, indicating the contamination level of total nitrogen is serious in the sediments. It is concluded that the countermeasures to manage the quality of sediments are required to improve the water quality in the Daechung Reservoir.

• Spatial Information Research
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• v.5 no.2
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• pp.133-146
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• 1997

While occasional disasters have occurred recently in urban facilities such as bridges, buildings, subways, roads and others, the systematic safety management of urban facilities is greatly needed to prevent the disaster or to minimize the damages. This study proposes the way of setting-up and managing an building disaster information system so that this experience can be applied to other urban facilities to minimize trials and errors. With such a purpose, this study presents a building safety management information system and utilizes it for the building disasten information system. This study includes research agendas as follows : building maintenance and management infonnation system, setting-up and utilization the building safety management infonnation system, building disaster infonnation system using GIS. The results suggest that the building safety management infonnation system which can be related to the urban disaster infonnation system should be constructed in advance in order to utilize the building disaster infonnation system, and that, under this condition, it proved to be easily connected to the related database, especially GIS. And, to utilize such an infonnation system, the application programs such as safety evaluation program, cost estimation program and documents management program should be readily available. In addition, other functional programs related with maintenance and management should be designed and established. The schemes or devices for practical usage should be supplemented through a standardization and a pilot project in central government or Seoul Metropolitan Government level in order to set up and utilize the building safety management infonnation system, and the related laws or regulations should be prepared or amended to support the system.