• Title/Summary/Keyword: ethylene oxide

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EFFECT OF DIFFERENT STERILIZATION METHODS ON THE SURFACE MORPHOLOGY OF PPDO-hybrid-PLGA NANOFIBER SCAFFOLD AND ATTACHMENTS OF PC12 CELL (다양한 소독방법이 PPDO-hybrid-PLGA nanofiber scaffold의 형태와 세포부착에 미치는 영향에 관한 연구)

  • Lee, Ju-Hyon;Min, Hyun-Gi;Jung, Ju-Young;Kang, Na-Ra
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.34 no.6
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    • pp.635-639
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    • 2008
  • Objectives : the effect of different sterilization methods on the surface morphology of PPDO-hybrid-PLGA nanofiber scaffold and attachments of PC12 cell were investigated. Methods : Poly (p-dioxone)-hybrid-Poly (lactide-glycolide) (PPDO-hybrid-PLGA) nanofiber scaffold, fabricated in a tube form with 1.5 mm internal diameter, 0.2 mm thickness and 5 mm length, was prepared using electrospinning method. To study the surface morphology using SEM, The study group and control group in respective were; Control:Non-sterilized scaffold, Group I:scaffold sterilized with 70% Alcohol, Group II: scaffold sterilized with Ethylene Oxide at $65^{\circ}C$, and Group III: scaffold sterilized with Ethylene Oxide at $37^{\circ}C$. To investigate viability of the PC12 cell on the scaffold, The study group and control group in respective were; Control: sterilized with 70% Alcohol, Group I: sterilized with Ethylene Oxide at $65^{\circ}C$, and Group II: sterilized with Ethylene Oxide at $37^{\circ}C$. Results : 1. The surface morphology was slightly changed in Group I, II and Group III, compared with control. 2. The attachment of PC12 cells in Group I, II was not higher than in control Discussion : The attachment of PC12 cell is not influenced by different sterilization methods.

Effect of Chemical Fumigant and ${\gamma}- Rays$ on the Physicochemical Properties of Dried Oak Mushrooms (표고버섯의 이화학적 특성에 대한 훈증제와 ${\gamma}-Rays$의 영향)

  • Kwon, Joong-Ho;Byun, Myung-Woo;Cho, Han-Ok;Kim, Young-Jae;Kim, Jong-Goon
    • Korean Journal of Food Science and Technology
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    • v.19 no.3
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    • pp.273-278
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    • 1987
  • The physicochemical properties of dried oak mushrooms were investigated to determine the comparative effects of ethylene oxide (E.O) fumigation and gamma irradiation with doses at 1 and 5 kGy. The total amino acid content was relatively stable in irradiated groups in comparison with the control. Treatments with gamma irradiation did not effect the content of reducing sugar but caused en increase in free sugars, such as mannitol, arabitol and trehalose. There were no significant differences in concentrations of minerals. The amount of water and fat soluble pigments and the rancidity of the samples stored at $25^{\circ}C$ increased with increasing the storage time and the relative humidity, and the tendency to change was more apparent in E.O. fumigated sample than gamma irradiated one.

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Synthesis of Polystyrene-b-Poly(ethylene oxide)-b-Polylactide Copolymers via Sequential Anionic and Ring-Opening Polymerizations (순차적 음이온 및 개환중합반응을 통한 폴리스티렌-폴리에틸렌옥사이드-폴리락티드 블록공증합체의 합성)

  • Song, Jie;Cho, Byoung-Ki
    • Polymer(Korea)
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    • v.33 no.5
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    • pp.458-462
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    • 2009
  • We have synthesized ABC linear triblock copolymers, i.e., polystyrene-b-poly(ethylene oxide)-b-polylactide, via sequential anionic and ring-opening polymerizations. In the first anionic polymerization step, styrene was polymerized in cyclohexane using sec-butyllithium as the initiator. Poly (styryl) lithium was hydroxylated by the addition of ethylene oxide, and the subsequent protonation with methanolic HCl. In the second anionic polymerization step, potassium naphthalenide was used to deprotonate the hydroxyl group of the PS to generate the macroinitiator of PS-$O^-K^+$. Polymerization of ethylene oxide was performed in THF and terminated with methanolic HCl. In the ring-opening polymerization step, the PS-b-PEO-$AlEt_2$ macroinitiator was prepared from an $AlEt_3$/pyridine system in THF, and the polymerization of lactide was performed at $90^{\circ}C$. The resulting block copolymers showed well-defined molecular weights and narrow molecular weight distributions as revealed by $^1H$- NMR spectroscopy and gel permeation chromatography (GPC).

Poly(ethylene oxide)/AgBF4/Al(NO3)3/Ag2O Composite Membrane for Olefin/Paraffin Separation (올레핀/파라핀 분리를 위한 poly(ethylene oxide)/AgBF4/Al(NO3)3/Ag2O 복합체 분리막)

  • Jeong, Sooyoung;Kang, Sang Wook
    • Membrane Journal
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    • v.27 no.4
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    • pp.313-318
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    • 2017
  • For the separation of olefins/paraffins, $Poly(ethylene oxide)(PEO)/AgBF_4/Al(NO_3)_3/Ag_2O$ composite membranes were prepared. When $Ag_2O$ was introduced, the initial selectivity and permeance of composite membranes were observed to be 13.7 and 21.7 GPU, respectively. The increase in performance compared to the initial performance of $PEO/AgBF_4/Al(NO_3)_3$ membrane (selectivity 13 and permeance 7.5 GPU) was thought to be due to the increase of Ag ion activity due to the addition of $Ag_2O$. However, performance degradation over time was observed, which was thought to be due to the polymer matrix PEO. Since the PEO polymer could not stabilize the $Ag_2O$ particles, the $Ag_2O$ particles becmae aggregated together as the solvent evaporates, and $Ag_2O$ acts as a barrier. As a result, the permeance decreases over time.

Fabrication of Poly(ethylene oxide)/Ag Nanoparticles/p-benzoquinone Composite Membrane Using AgNO3 Precursor for Olefin/Paraffin Separation (올레핀/파라핀 분리용 AgNO3 전구체를 활용한 poly(ethylene oxide)/Ag nanoparticles/p-benzoquinone 복합체 분리막 제조)

  • kim, Minsu;Kang, Sang Wook
    • Membrane Journal
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    • v.28 no.4
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    • pp.260-264
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    • 2018
  • Poly (ethylene oxide) (PEO)/Ag nanoparticles (AgNPs)(precursor : $AgBF_4$)/p-benzoquinone (p-BQ) composite membrane was prepared for olefin/paraffin separation. As a result, the performance of composite membrane was observed to be maintained at selectivity of 10 and permeance of 15 GPU up to 100 hours. The performance of the membrane was maintained for 100 hours was attributable to that Ag ions could be converted into stable Ag NPs by addition of p-BQ. Furthermore, the surface was partially polarized by the electron acceptor p-BQ, resulting in the formation of olefin carrier. In this study, since the cost of $AgBF_4$ used as a precursor of Ag NPs was relatively higher, $AgNO_3$ was utilized. As a result, it was confirmed that $AgNO_3$ couldn't show the stable formation of nanoparticle, resulting in the poor separation performance.

Comparative Effects of Gamma Irradiation and Ethylene Oxide Fumigation on Some Chemical Quality of White Ginseng Powder (백삼분말의 몇가지 화학적 품질 특성에 대한 감마선과 에틸렌 옥시드 처리의 영향)

  • Kwon, Joong-Ho;Byun, Myung-Woo;Cho, Han-Ok;Han, Byung-Hoon
    • Korean Journal of Food Science and Technology
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    • v.26 no.3
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    • pp.278-282
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    • 1994
  • Ginseng saponins and proximate components were considerably resistant to both gamma irradiation at less than 10 kGy and commercial ethylene oxide cycle, while sulfur-containing amino acids, reducing sugar, pH, and acidity of white ginseng powder were significantly changed by EO fumigation. The contents of saponins, reducing sugar, pH and acidity were relatively liable to change under the higher relative humidity (90%), especially in the non-treated control sample. However, irradiated samples at optimum-dose range (5 to 10 kGy) depending on the microbial load following airtight packaging showed a good chemical quality for 7 months of storage at $30{\pm}2^{\circ}C$ irrespective of relative humidity.

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Effects of Ethylene Oxide Fumigation and Gamma Irradiation on the Quality of Ground Red and Black Peppers (Ethylene Oxide처리와 감마선 조사가 고추 및 후추가루의 품질에 미치는 영향)

  • Cho, Han-Ok;Kwon, Joong-Ho;Byun, Myung-Woo;Kim, Young-Jae;Yang, Jae-Seung
    • Korean Journal of Food Science and Technology
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    • v.18 no.4
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    • pp.294-300
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    • 1986
  • Ethylene oxide (E.O) fumigation and gamma irradiation were applied to comparative researches on the sterilizing effect and physicochemical quality of sound red and black peppers. The microorganisms contaminated in the sample, including total bacteria, aerobic spores, acid tolerant bacteria, fungi, osmophilic molds and coliforms were sterilized with irradiation doses of 7 10 kGy, while E.O fumigation in a commonly used condition proved insufficient for the destruction of them. Both treatments affected more or less chemical components of the sample, such as pungent principle, pigment, essential oils and volatile flavors, but the gamma irradiation at the doses for radurization and radicidation was shown to be safer than E.O fumigation.

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Quality Evaluation of Ground Garlic and Onions Treated with Chemical Fumigants and Ionizing Radiation (마늘 및 양파 분말의 품질에 대한 화학 훈증제와 감마선 처리의 비교 연구)

  • Kwon, Joong-Ho;Byun, Myung-Woo;Cho, Han-Ok
    • Korean Journal of Food Science and Technology
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    • v.19 no.2
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    • pp.107-112
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    • 1987
  • Comparative effects of ethylene oxide and gamma radiation treatment of the microbiological and physicochemical qualities of ground garlic and onions were investigated. The standard ethylene oxide cycle employed was substantially less effective in reducing microbial counts than were 7 and 10 kGy of gamma radiation, and was roughly comparable to 5 kGy. Effects of gamma radiation on pungency, nutrient and color were relativey small in comparison with ethylene oxide which adversely affected physicochemical properties. Sensory evaluation indicated that no significant difference was observed between the nontreated control group and 10 kGy irradiated smaples.

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